-
2
-
-
79952043187
-
Navigating the road toward optimal initial therapy for chronic myeloid leukemia
-
Okimoto RA, Van Etten RA. Navigating the road toward optimal initial therapy for chronic myeloid leukemia. Curr Opin Hematol. 2011;18:89-97.
-
(2011)
Curr Opin Hematol
, vol.18
, pp. 89-97
-
-
Okimoto, R.A.1
Van Etten, R.A.2
-
3
-
-
51649123760
-
A review of Judah Folkman's remarkable achievements in biomedicine
-
Cao Y, Langer R. A review of Judah Folkman's remarkable achievements in biomedicine. Proc Natl Acad Sci USA. 2008;105:13203-13205.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13203-13205
-
-
Cao, Y.1
Langer, R.2
-
4
-
-
80051739930
-
Chronic myeloid leukemia 2011: Successes, challenges, and strategies: Proceedings of the 5th annual BCR-ABL1 positive and BCR-ABL1 negative myeloproliferative neoplasms workshop
-
Mughal TI, Radich JP, Van Etten RA, Quintas-Cardama A, Skorski T, Ravandi F, DeAngelo DJ, Gambacorti-Passerini C, Martinelli G, Tefferi A. Chronic myeloid leukemia 2011: successes, challenges, and strategies: Proceedings of the 5th annual BCR-ABL1 positive and BCR-ABL1 negative myeloproliferative neoplasms workshop. Am J Hematol. 2011; 86:811-819.
-
(2011)
Am J Hematol
, vol.86
, pp. 811-819
-
-
Mughal, T.I.1
Radich, J.P.2
Van Etten, R.A.3
Quintas-Cardama, A.4
Skorski, T.5
Ravandi, F.6
Deangelo, D.J.7
Gambacorti-Passerini, C.8
Martinelli, G.9
Tefferi, A.10
-
5
-
-
79959950762
-
Novel therapeutic targets for the treatment of heart failure
-
Tamargo J, Lopez-Sendon J. Novel therapeutic targets for the treatment of heart failure. Nat Rev Drug Disc. 2011;10:536-555.
-
(2011)
Nat Rev Drug Disc
, vol.10
, pp. 536-555
-
-
Tamargo, J.1
Lopez-Sendon, J.2
-
6
-
-
79551610758
-
Cardiotoxicity of kinase inhibitors: The prediction and translation of preclinical models to clinical outcomes
-
Force T, Kolaja KL. Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes. Nat Rev Drug Disc. 2011;10:111-126.
-
(2011)
Nat Rev Drug Disc
, vol.10
, pp. 111-126
-
-
Force, T.1
Kolaja, K.L.2
-
7
-
-
50949132320
-
Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics
-
Chen MH, Kerkela R, Force T. Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics. Circulation. 2008;118:84-95.
-
(2008)
Circulation
, vol.118
, pp. 84-95
-
-
Chen, M.H.1
Kerkela, R.2
Force, T.3
-
8
-
-
84860346274
-
Pulmonary arterial hypertension in patients treated by dasatinib
-
Montani D, Bergot E, Gunther S, Savale L, Bergeron A, Bourdin A, Bouvaist H, Canuet M, Pison C, Macro M, Poubeau P, Girerd B. Natali D, Guignabert C, Perros F, O'Callaghan DS, Jais X, Tubert-Bitter P, Zalcman G, Sitbon O, Simonneau G, Humbert M. Pulmonary arterial hypertension in patients treated by dasatinib. Circulation. 2012;125:2128-2137.
-
(2012)
Circulation
, vol.125
, pp. 2128-2137
-
-
Montani, D.1
Bergot, E.2
Gunther, S.3
Savale, L.4
Bergeron, A.5
Bourdin, A.6
Bouvaist, H.7
Canuet, M.8
Pison, C.9
MacRo, M.10
Poubeau, P.11
Girerd, B.12
Natali, D.13
Guignabert, C.14
Perros, F.15
O'Callaghan, D.S.16
Jais, X.17
Tubert-Bitter, P.18
Zalcman, G.19
Sitbon, O.20
Simonneau, G.21
Humbert, M.22
more..
-
9
-
-
63349083357
-
Reversible severe pulmonary hypertension secondary to dasatinib in a patient with chronic myeloid leukemia
-
Rasheed W, Flaim B, Seymour JF. Reversible severe pulmonary hypertension secondary to dasatinib in a patient with chronic myeloid leukemia. Leuk Res. 2009;33:861-864.
-
(2009)
Leuk Res
, vol.33
, pp. 861-864
-
-
Rasheed, W.1
Flaim, B.2
Seymour, J.F.3
-
10
-
-
79955500900
-
A phase 2 trial of dasatinib in advanced melanoma
-
Kluger HM, Dudek AZ, McCann C, Ritacco J, Southard N, Jilaveanu LB, Molinaro A, Sznol M. A phase 2 trial of dasatinib in advanced melanoma. Cancer. 2011;117:2202-2208.
-
(2011)
Cancer
, vol.117
, pp. 2202-2208
-
-
Kluger, H.M.1
Dudek, A.Z.2
McCann, C.3
Ritacco, J.4
Southard, N.5
Jilaveanu, L.B.6
Molinaro, A.7
Sznol, M.8
-
11
-
-
77956709644
-
Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy
-
Ghofrani HA, Morrell NW, Hoeper MM, Olschewski H, Peacock AJ, Barst RJ, Shapiro S, Golpon H, Toshner M, Grimminger F, Pascoe S. Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy. Am J Respir Crit Care Med. 2010;182:1171-1177.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1171-1177
-
-
Ghofrani, H.A.1
Morrell, N.W.2
Hoeper, M.M.3
Olschewski, H.4
Peacock, A.J.5
Barst, R.J.6
Shapiro, S.7
Golpon, H.8
Toshner, M.9
Grimminger, F.10
Pascoe, S.11
-
12
-
-
78649719727
-
Targeting non-malignant disorders with tyrosine kinase inhibitors
-
Grimminger F, Schermuly RT, Ghofrani HA. Targeting non-malignant disorders with tyrosine kinase inhibitors. Nat Rev Drug Disc. 2010;9: 956-970.
-
(2010)
Nat Rev Drug Disc
, vol.9
, pp. 956-970
-
-
Grimminger, F.1
Schermuly, R.T.2
Ghofrani, H.A.3
-
13
-
-
26444540768
-
Reversal of experimental pulmonary hypertension by PDGF inhibition
-
Schermuly RT, Dony E, Ghofrani HA, Pullamsetti S, Savai R, Roth M, Sydykov A, Lai YJ, Weissmann N, Seeger W, Grimminger F. Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clinical Invest. 2005;115:2811-2821.
-
(2005)
J Clinical Invest
, vol.115
, pp. 2811-2821
-
-
Schermuly, R.T.1
Dony, E.2
Ghofrani, H.A.3
Pullamsetti, S.4
Savai, R.5
Roth, M.6
Sydykov, A.7
Lai, Y.J.8
Weissmann, N.9
Seeger, W.10
Grimminger, F.11
-
14
-
-
78650657590
-
Tinkering outside the kinase ATP box: Allosteric (type IV) and bivalent (type V) inhibitors of protein kinases
-
Cox KJ, Shomin CD, Ghosh I. Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases. Future Med Chem. 2011;3:29-43.
-
(2011)
Future Med Chem
, vol.3
, pp. 29-43
-
-
Cox, K.J.1
Shomin, C.D.2
Ghosh, I.3
-
15
-
-
68949147006
-
Measuring and interpreting the selectivity of protein kinase inhibitors
-
Smyth LA, Collins I. Measuring and interpreting the selectivity of protein kinase inhibitors. J Chem Biol. 2009;2:131-151.
-
(2009)
J Chem Biol
, vol.2
, pp. 131-151
-
-
Smyth, L.A.1
Collins, I.2
-
16
-
-
36849056267
-
An anti-cancer c-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic
-
Fernández A, Sanguino A, Peng Z, Ozturk E, Chen J, Crespo A, Wulf S, Shavrin A, Qin C, Ma J, Trent J, Lin Y, Han HD, Mangala LS, Bankson JA, Gelovani J, Samarel A, Bornmann W, Sood AK, Lopez-Berestein G. An anti-cancer c-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic. J Clin Invest. 2007;117:4044-4054.
-
(2007)
J Clin Invest
, vol.117
, pp. 4044-4054
-
-
Fernández, A.1
Sanguino, A.2
Peng, Z.3
Ozturk, E.4
Chen, J.5
Crespo, A.6
Wulf, S.7
Shavrin, A.8
Qin, C.9
Ma, J.10
Trent, J.11
Lin, Y.12
Han, H.D.13
Mangala, L.S.14
Bankson, J.A.15
Gelovani, J.16
Samarel, A.17
Bornmann, W.18
Sood, A.K.19
Lopez-Berestein, G.20
more..
-
17
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med. 2007;356:115-124.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
18
-
-
36849023013
-
Cardiotoxicity associated with tyronise kinase inhibitor sunitinib
-
Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, Schoen FJ, Van den Abbeele AD, Demetri GD, Force T, Chen MH. Cardiotoxicity associated with tyronise kinase inhibitor sunitinib. Lancet. 2007:370;2011-2019.
-
(2007)
Lancet
, vol.370
, pp. 2011-2019
-
-
Chu, T.F.1
Rupnick, M.A.2
Kerkela, R.3
Dallabrida, S.M.4
Zurakowski, D.5
Nguyen, L.6
Woulfe, K.7
Pravda, E.8
Cassiola, F.9
Desai, J.10
George, S.11
Morgan, J.A.12
Harris, D.M.13
Ismail, N.S.14
Chen, J.H.15
Schoen, F.J.16
Van Den Abbeele, A.D.17
Demetri, G.D.18
Force, T.19
Chen, M.H.20
more..
|