Co-expression of SNAIL and TWIST determines prognosis in estrogen receptor-positive early breast cancer patients

Breast Cancer Research and Treatment

Volumn 133, Issue 1, 2012, Pages 49-59

  Van Nes, Johanna G H ^a,b   De Kruijf, Esther M ^a   Putter, Hein ^a   Faratian, Dana ^c   Munro, Alison ^c   Campbell, Fiona ^c   Smit, Vincent T H B M ^a   Liefers, Gerrit Jan ^a   Kuppen, Peter J K ^a   Van De Velde, Cornelis J H ^a   Bartlett, John M S ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Early breast cancer; Prognostic factors; SLUG; SNAIL; TWIST

Indexed keywords

ESTROGEN RECEPTOR; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER RELAPSE; COHORT ANALYSIS; EPITHELIAL MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NETHERLANDS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RELAPSE FREE PERIOD; RETROSPECTIVE STUDY; TISSUE MICROARRAY; UNIVERSITY HOSPITAL;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CADHERINS; CARCINOMA, DUCTAL, BREAST; FEMALE; GENE EXPRESSION; HUMANS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; NUCLEAR PROTEINS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECEPTORS, ESTROGEN; RETROSPECTIVE STUDIES; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; TWIST TRANSCRIPTION FACTOR; YOUNG ADULT;

EID: 84860337922     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1684-y     Document Type: Article

References (32)

1. DM Parkin F Bray J Ferlay 2005 Pisani P: global cancer statistics, 2002 CA Cancer J Clin 55 74 108 15761078 10.3322/canjclin.55.2.74 (Pubitemid 40372904)
2. Early Breast Cancer Trialists' Collaborative Group 2005 Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials Lancet 365 1687 1717 10.1016/S0140-6736(05)66544-0 (Pubitemid 40719106)
3. JP Thiery H Acloque RY Huang MA Nieto 2009 Epithelial-mesenchymal transitions in development and disease Cell 139 871 890 19945376 10.1016/j.cell.2009.11.007 1:CAS:528:DC%2BC3cXksFWltA%3D%3D
4. W Birchmeier J Behrens 1994 Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness Biochim Biophys Acta 1198 11 26 8199193 1:CAS:528:DyaK2cXktlaisrs%3D (Pubitemid 24159061)
5. JP Thiery 2002 Epithelial-mesenchymal transitions in tumor progression Nat Rev Cancer 2 442 454 12189386 10.1038/nrc822 1:CAS:528:DC%2BD38Xksl2ltr8%3D
6. J Yang RA Weinberg 2008 Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis Dev Cell 14 818 829 18539112 10.1016/j.devcel.2008.05.009 1:CAS:528:DC%2BD1cXnsVCrs7g%3D (Pubitemid 351757205)
7. H Peinado D Olmeda A Cano 2007 Snail, Zeb and bHLH factors in tumor progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7 415 428 17508028 10.1038/nrc2131 1:CAS:528:DC%2BD2sXls1Kjs70%3D (Pubitemid 46809165)
8. E Rosivatz I Becker K Specht E Fricke B Luber R Busch H Hofler KF Becker 2002 Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer Am J Pathol 161 1881 1891 12414534 10.1016/S0002-9440(10)64464-1 1:CAS:528:DC%2BD38XptV2gtbk%3D (Pubitemid 35265545)
9. GQ Ru HJ Wang WJ Xu ZS Zhao 2010 Upregulation of twist in gastric carcinoma associated with tumor invasion and poor prognosis Pathol Oncol Res 17 2 341 347 21104359 10.1007/s12253-010-9332-0
10. JJ Hung MH Yang HS Hsu WH Hsu JS Liu KJ Wu 2009 Prognostic significance of hypoxia-inducible factor-1alpha, TWIST1 and Snail expression in resectable non-small cell lung cancer Thorax 64 1082 1089 19778933 10.1136/thx.2009.115691
11. WK Kwok MT Ling TW Lee TC Lau C Zhou X Zhang CW Chua KW Chan FL Chan C Glackin YC Wong X Wang 2005 Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target Cancer Res 65 5153 5162 15958559 10.1158/0008-5472.CAN-04-3785 1:CAS:528:DC%2BD2MXltFemurw%3D (Pubitemid 40827324)
12. TA Martin A Goyal G Watkins WG Jiang 2005 Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer Ann Surg Oncol 12 488 496 15864483 10.1245/ASO.2005.04.010 (Pubitemid 40884264)
13. MH Yang CL Chen GY Chau SH Chiou CW Su TY Chou WL Peng JC Wu 2009 Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma Hepatology 50 1464 1474 19821482 10.1002/hep.23221 1:CAS:528:DC%2BD1MXhsV2js7zN
14. MH Yang MZ Wu SH Chiou PM Chen SY Chang CJ Liu SC Teng KJ Wu 2008 Direct regulation of TWIST by HIF-1alpha promotes metastasis Nat Cell Biol 10 295 305 18297062 10.1038/ncb1691 1:CAS:528:DC%2BD1cXislaksrc%3D (Pubitemid 351331016)
15. SH Park LW Cheung AS Wong PC Leung 2008 Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha Mol Endocrinol 22 2085 2098 18550773 10.1210/me.2007-0512 1:CAS:528:DC%2BD1cXhtV2itL%2FP
16. M Shioiri T Shida K Koda K Oda K Seike M Nishimura S Takano M Miyazaki 2006 Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients Br J Cancer 94 1816 1822 16773075 10.1038/sj.bjc.6603193 1:CAS:528:DC%2BD28XlsFequ7s%3D (Pubitemid 43882571)
17. Y Uchikado S Natsugoe H Okumura T Setoyama M Matsumoto S Ishigami T Aikou 2005 Slug expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma Clin Cancer Res 11 1174 1180 15709186 1:CAS:528:DC%2BD2MXht1yntL4%3D (Pubitemid 40175768)
18. Q Yu K Zhang X Wang X Liu Z Zhang 2010 Expression of transcription factors snail, slug, and twist in human bladder carcinoma J Exp Clin Cancer Res 29 119 20809941 10.1186/1756-9966-29-119 1:CAS:528:DC%2BC3cXmtVKhsLw%3D
19. T Kosaka E Kikuchi S Mikami A Miyajima S Shirotake M Ishida Y Okada M Oya 2010 Expression of snail in upper urinary tract urothelial carcinoma: prognostic significance and implications for tumor invasion Clin Cancer Res 16 5814 5823 20947514 10.1158/1078-0432.CCR-10-0230 1:CAS:528:DC%2BC3cXhsFamtLvO
20. K Shibata H Kajiyama K Ino M Terauchi E Yamamoto A Nawa S Nomura F Kikkawa 2008 Twist expression in patients with cervical cancer is associated with poor disease outcome Ann Oncol 19 81 85 17925286 10.1093/annonc/mdm344 1:STN:280:DC%2BD1c%2FgtVequw%3D%3D
21. SE Moody D Perez TC Pan CJ Sarkisian CP Portocarrero CJ Sterner KL Notorfrancesco RD Cardiff LA Chodosh 2005 The transcriptional repressor Snail promotes mammary tumor recurrence Cancer Cell 8 197 209 16169465 10.1016/j.ccr.2005.07.009 1:CAS:528:DC%2BD2MXhtV2gt7rF (Pubitemid 41317591)
22. LM McShane DG Altman W Sauerbrei SE Taube M Gion GM Clark 2005 Reporting recommendations for tumor marker prognostic studies J Nath Cancer Inst 97 1180 1184 10.1093/jnci/dji237 1:CAS:528:DC%2BD2MXpsVaks7s%3D (Pubitemid 41258223)
23. JGH van Nes EM de Kruijf D Faratian CJ van de Velde H Putter C Falconer VT Smit C Kay MJ van de Vijver PJ Kuppen JM Bartlett 2011 COX2 expression in prognosis and in prediction to endocrine therapy in early breast cancer patients Breast Cancer Res Treat 125 671 685 20358279 10.1007/s10549-010-0854-7
24. T Kirkegaard J Edwards S Tovey LM McGlynn SN Krishna R Mukherjee L Tam AF Munro B Dunne JM Bartlett 2006 Observer variation in immunohistochemical analysis of protein expression, time for a change? Histopathology 48 787 794 16722926 10.1111/j.1365-2559.2006.02412.x 1:STN:280:DC%2BD283ptleqsw%3D%3D (Pubitemid 43800937)
25. H Putter M Fiocco RB Geskus 2007 Tutorial in biostatistics: competing risks and multi-state models Stat Med 26 2389 2430 17031868 10.1002/sim.2712 1:STN:280:DC%2BD2s3hs1agsA%3D%3D (Pubitemid 46730255)
26. Altman DG, Machin D, Bryant TN, Gardner MJ (2000) Statistics with confidence. British Medical Journal Books, Bristol
27. SA Mani W Guo MJ Liao EN Eaton A Ayyanan AY Zhou M Brooks F Reinhard CC Zhang M Shipitsin LL Campbell K Polyak C Brisken J Yang RA Weinberg 2008 The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 704 715 18485877 10.1016/j.cell.2008.03.027 1:CAS:528: DC%2BD1cXmsVOru7w%3D (Pubitemid 351636299)
28. YT Ip RE Park D Kosman K Yazdanbakhsh M Levine 1992 Dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo Genes Dev 6 1518 1530 1644293 10.1101/gad.6.8.1518 1:CAS:528:DyaK38XlsVOmsbs%3D
29. MA Smit TR Geiger JY Song I Gitelman DS Peeper 2009 A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis Mol Cell Biol 29 3722 3737 19414595 10.1128/MCB.01164-08 1:CAS:528:DC%2BD1MXotlCqurs%3D
30. C Come V Arnoux F Bibeau P Savagner 2004 Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression J Mammary Gland Biol Neoplasia 9 183 193 15300012 10.1023/B:JOMG.0000037161.91969.de (Pubitemid 39177502)
31. D Gallo C Ferlini G Scambia 2010 The epithelial-mesenchymal transition and the estrogen-signaling in ovarian cancer Curr Drug Targets 11 474 481 20015012 10.2174/138945010790980385 1:CAS:528:DC%2BC3cXkvV2jsbc%3D
32. RB Hazan GR Phillips RF Qiao L Norton SA Aaronson 2000 Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis J Cell Biol 148 779 790 10684258 10.1083/jcb.148.4.779 1:CAS:528:DC%2BD3cXhsVOqsLw%3D