2-Aminothiophenes as building blocks in heterocyclic synthesis: Synthesis and antimicrobial evaluation of a new class of pyrido[1,2-a]thieno[3,2-e] pyrimidine, quinoline and pyridin-2-one derivatives

European Journal of Medicinal Chemistry

Volumn 52, Issue , 2012, Pages 51-65

  Behbehani, Haider ^a   Ibrahim, Hamada Mohamed ^b   Makhseed, Saad ^a   Elnagdi, Mohamed H ^a   Mahmoud, Huda ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b Fayoum University   (Egypt)

Author keywords

2 Aminothiophene; Antimicrobial activity; Cyanoacetamides; Cyanoacetic acid; Pyridin 2 one; Pyrido 1,2 a thieno 3,2 e pyrimidine

Indexed keywords

2 AMINOTHIOPHENE; 4 AMINOPYRAZOLE; 5 AMINOPYRAZOLE; ACETIC ACID DERIVATIVE; ACETIC ANHYDRIDE; ANTIINFECTIVE AGENT; CYANOACETAMIDE; CYANOACETIC ACID; CYCLOHEXIMIDE; ENAMINE; HYDRAZINE; NEW DRUG; PENICILLIN DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDIN 2 ONE; PYRIDO[1,2 A]THIENO[3,2 E]PYRIMIDINE; QUINOLINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; GAS CHROMATOGRAPHY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MASS SPECTROMETRY; MICROWAVE IRRADIATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; YEAST;

ANTI-INFECTIVE AGENTS; CHEMISTRY TECHNIQUES, SYNTHETIC; PYRIDONES; PYRIMIDINES; QUINOLINES; THIOPHENES;

EID: 84860330558     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.03.004     Document Type: Article

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