P-glycoprotein: Why this drug transporter may be clinically important

Current Psychiatry

Volumn 11, Issue 3, 2012, Pages 38-40

  Levin, Gary M ^a  

^a ROSEMAN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450; GLYCOPROTEIN P; INDINAVIR; LAMIVUDINE; VENLAFAXINE; ZIDOVUDINE;

ADULT; ANHEDONIA; AREA UNDER THE CURVE; CASE REPORT; CONCENTRATION (PARAMETERS); DRUG ABSORPTION; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG EFFICACY; DRUG HALF LIFE; DRUG TREATMENT FAILURE; FATIGUE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETHARGY; MAJOR DEPRESSION; MALE; NOTE; PROTEIN FUNCTION; PROTEIN TRANSPORT; VIRUS LOAD; VIRUS REPLICATION; WEIGHT REDUCTION;

EID: 84860330509     PISSN: 15378276     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (9)

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5. Ehret MJ, Levin GM, Narasimhan M, et al. Venlafaxine induces P-glycoprotein in human Caco-2 cells. Hum Psychopharmacol. 2007;22(1):49-53.
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7. Rosenberg MF, Bikadi Z, Chan J, et al. The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone. Structure. 2010;18(4):482-493.
8. Oesterheld J. P-glycoprotein (PGP) table - the effect of drugs and foods. http://www.genemedrx.com/PGPtable.php. Accessed February 3, 2012.
9. Kim RB. Drugs as P-glycoprotein substrates, inhibitors, and inducers. Drug Metab Rev. 2002;34(1-2):47-54.