Hereditary breast cancer in Middle Eastern and North African (MENA) populations: Identification of novel, recurrent and founder BRCA1 mutations in the Tunisian population

Molecular Biology Reports

Volumn 39, Issue 2, 2012, Pages 1037-1046

  Mahfoudh, Wijden ^a   Bouaouina, Noureddine ^a,b   Ahmed, Slim Ben ^b   Gabbouj, Sallouha ^a   Shan, Jingxuan ^c   Mathew, Rebecca ^c   Uhrhammer, Nancy ^d   Bignon, Yves Jean ^d   Troudi, Wafa ^e   Ammar Elgaaied, Amel Ben ^e   Hassen, Elham ^a   Chouchane, Lotfi ^c  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b FARHAT HACHED HOSPITAL   (Tunisia)

^c WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^d CENTRE JEAN PERRIN   (France)

^e FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

Author keywords

BRCA1 mutations; Founder effect; Hereditary breast cancer; Tunisians

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CLINICAL ARTICLE; DNA FLANKING REGION; EXON; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; HAPLOTYPE; HIGH RISK POPULATION; HUMAN; INTRON; MALE; MICROSATELLITE MARKER; MIDDLE EAST; NORTH AFRICA; ONCOGENE; PEDIGREE ANALYSIS; TUNISIA; BREAST TUMOR; DNA SEQUENCE; ETHNOLOGY; GENE DELETION; GENETIC COUNSELING; GENETIC PREDISPOSITION; GENETICS; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PEDIGREE; POPULATION GENETICS; TUMOR SUPPRESSOR GENE;

MICROSATELLITE DNA;

BASE SEQUENCE; BREAST NEOPLASMS; FEMALE; GENES, BRCA1; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; GERM-LINE MUTATION; HAPLOTYPES; HUMANS; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; PEDIGREE; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TUNISIA;

EID: 84860318904     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-011-0829-8     Document Type: Article

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