Multifunctional targeted radiotherapy system for induced tumours expressing gastrin-releasing peptide receptors

Current Nanoscience

Volumn 8, Issue 2, 2012, Pages 193-201

  Jiménez Mancilla, Nallely ^a,b   Ferro Flores, Guillermina ^a   Ocampo García, Blanca ^a   Luna Gutiérrez, Myrna ^a,b   de María Ramírez, Flor ^a   Pedraza López, Martha ^c   Torres García, Eugenio ^b  

^a INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MÉXICO   (Mexico)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

177Lu gold nanoparticles; 99mTcgold nanoparticles; Radiolabelled gold nanoparticles; Radiolabelled Lys3 bombesin Tat(49 57); Targeted radiotherapy

Indexed keywords

ABSORBED DOSE; CANCER CELLS; CELL-PENETRATING PEPTIDE; ENERGY DEPOSITIONS; GOLD NANOPARTICLE; GOLD NANOPARTICLES; HIGH AFFINITY; HIV TAT; MULTIFUNCTIONAL SYSTEMS; PEPTIDE RECEPTOR; PROSTATE CANCERS; RADIOCHEMICAL PURITY; RADIOLABELLED LYS3-BOMBESIN-TAT(49-57); SH GROUPS; SPONTANEOUS REACTIONS; TARGETED RADIONUCLIDE THERAPIES; TARGETED RADIOTHERAPY; THIOL GROUPS;

AMINO ACIDS; AUGERS; CELLS; DNA; ELECTRON EMISSION; METAL NANOPARTICLES; RADIOTHERAPY; TUMORS;

PEPTIDES;

BOMBESIN; CYSTEINE; GASTRIN RELEASING PEPTIDE RECEPTOR; GOLD NANOPARTICLE; LUTETIUM 177; PEPTIDE; PEPTIDE TAT (49 57); TECHNETIUM 99M; TETRAXETAN; THIOL GROUP; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RADIOTHERAPY; CELL NUCLEUS; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG PURITY; FAR INFRARED SPECTROSCOPY; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; ISOTOPE LABELING; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; RADIATION DOSE; RADIOCHEMISTRY; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY;

MUS;

EID: 84860315703     PISSN: 15734137     EISSN: 18756786     Source Type: Journal    
DOI: 10.2174/157341312800167678     Document Type: Article

References (36)

1. 3] octreotate. Q. J. Nucl. Med. Mol. Imaging., 2006, 50, 265-271.
2. Panigone, S.; Nunn, A.D. Lutetium-177-labeled gastrin releasing peptide receptor binding analogs: a novel approach to radionuclide therapy. Q. J. Nucl. Med. Mol. Imaging., 2006, 50, 310-321.
3. 177Lulabeled bombesin derivatives with amino acidic spacers for selective targeting of human PC-3 prostate tumor cells. Q. J. Nucl. Med. Mol. Imaging., 2011, 55, 310-323.
4. 177Lu-DOTATATE in athymic mice with induced pancreatic malignant tumours: preclinical studies. Radiat. Eff. Defects Solids., 2007, 162, 791-796.
5. Buchegger, F.; Perillo-Adamer, F.; Dupertuis, Y.M.; Bischof, A. Auger radiation targeted into DNA: a therapy perspective. Eur. J. Nucl. Med. Mol. Imaging, 2006, 33, 1352-1363.
6. 99mTc Auger electrons for targeted tumor radiotherapy by computational methods. Med. Phys., 2010, 37, 3551-3559.
7. 3]-bombesin for imaging gastrin-releasing peptide receptor-positive tumours. Nucl. Med. Commun., 2006, 27, 371-376.
8. 3-bombesin. Appl. Radiat. Isot., 2010, 68, 2274-2278.
9. 3]-bombesin: biokinetics and dosimetry in women. Nucl. Med. Commun., 2008, 29, 741-747.
10. 111In]-labelled HIV-1 tat peptide radioimmunoconjugates in tumorbearing mice following intravenous or intratumoral injection. Nucl. Med. Biol., 2008, 35, 101-110.
11. Costantini, D.L.; Hu, M.; Reilly, R. Peptide motifs for insertion of radiolabeled biomolecules into cells and routing to the nucleus for cancer imaging or radiotherapeutic applications. Cancer Biother. Radiopharm., 2008, 23, 3-24.
12. 2-Tat(49-57)-bombesin: a target-specific hybrid radiopharmaceutical. Int. J. Pharm., 2009, 375, 75-83.
13. 2-Tat(49-57)-bombesin internalized in nuclei of prostate and breast cancer cells: kinetics, dosimetry and effect on cellular proliferation. Nucl. Med. Commun., 2011, 32, 303-313.
14. Levy, R.; Thanh, N.T.K.; Doty, R.C.; Hussain, I.; Nichols, R.J.; Schiffrin, D.J. Rational and combinatorial design of peptide capping ligands for gold nanoparticles. J. Am. Chem. Soc., 2004, 126, 10076-10084.
15. De la Fuente, J.M.; Berry, C.C. Tat peptide as an efficient molecule to translocate gold nanoparticles into the cell nucleus. Bioconjug. Chem., 2005, 16, 1176-1180.
16. Porta, F.; Speranza, G.; Krpetic, Z.; Santo, V.D.; Francescato, P.; Scari, G. Gold nanoparticles capped by peptides. Mater. Sci. Eng. B., 2007, 140, 187-194.
17. 2 can modify the conjugation and stability of gold nanoparticles and their affinity for betaamyloid fibrils. Bioconjug. Chem., 2008, 19, 1154-1163.
18. 3]octreotide peptide. Biophys. Chem., 2008, 138, 83-90.
19. 99mTc-labeled gold nanoparticles for in vivo gastrin releasing peptide-receptor imaging. J. Biomed. Nanotech., 2010, 6, 375-384.
20. 99mTc-labeled gold nanoparticles capped with HYNIC-peptide/mannose for sentinel lymph node detection. Nucl. Med. Biol., 2011, 38, 1-11.
21. 3 expression. Bioconjug. Chem., 2011, 22, 913-922.
22. Wang, H.; Dimitrov, K. Conjugation of immunoglobulin M to gold nanoparticles. Curr. Nanosci., 2011, 7, 874-878.
23. Elfeky, S.A.; Al-Sherbini, A.A. Synthesis and spectral characteristics of gold nanoparticles labelled with fluorescein sodium. Curr. Nanosci., 2011, 7, 1028-1033.
24. Chanda, N.; Kattumuri, V.; Shukla, R.; Zambre, A.; Katti, K.; Upendran, A. Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity. Proc. Natl. Acad. Sci. USA, 2010, 107, 8760-8765.
25. Jadzinsky, P.D.; Calero, G.; Ackerson, C.J.; Bushnell, D.A.; Komberg, R.D. Structure of a thiol monolayer-protected gold nanoparticle at 1.1 A resolution. Science, 2007, 318, 430-433.
26. 99mTcradiopharmaceuticals based on gold nanoparticles. Nucl. Med. Commun., 2011, 32, 1095-1104.
27. 177Lu radionuclides. Cancer Biother. Radiopharm., 2005, 20, 436-449.
28. Kogan, M.J.; Olmedo, I.; Hosta, L.; Guerrero, A.R.; Cruz, L.J.; Albericio, F. Peptides and metallic nanoparticles for biomedical applications. Nanomedicine, 2007, 2, 287-306.
29. Petroski, J.; Chou, M.; Creutz, C. The coordination chemistry of gold surface: formation and far-infrared spectra of alkanethiolate-capped gold nanoparticles. J. Org. Chem., 2009, 694, 1138-1143.
30. Kato, H.S.; Noh, J.; Hara, M.; Kawai, M.; An HREELS Study of Alkanethiol Self-Assembled Monolayers on Au(111). J. Phys. Chem. B., 2002, 106, 9655-9658.
31. Hirsch, L.R.; Stafford, R.J.; Bankson, J.A.; Sershen, S.R.; Rivera, B.; Price, R.E.; Hazle, J.D.; Hals, N.J. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc. Natl. Acad. Sci. USA, 2003, 100, 13549-13554.
32. Huang, X.; Neretina, S.; El-Sayed, M.A. Gold nanorods: from synthesis and properties to biological and biomedical applications. Adv. Mater., 2009, 21, 4880-4910.
33. Elbialy, N.; Abdelhamid, M.; Youssef, T. Low power argon laser-induced thermal therapy for subcutaneous ehrlich carcinoma in mice using spherical gold nanoparticles. J. Biomed. Nanotech., 2010, 6, 687-693.
34. Huang, X.; Qian, W.; El-Sayed, I.H.; El-Sayed, M.A. The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal cancer therapy. Lasers Surg. Med., 2007, 39, 747-753.
35. 188Re-pharmaceuticals. Adv. Drug Deliv. Rev., 2008, 60, 1389-1401.
36. Berry, C.C.; de la Fuente, J.M.; Mullin, M.; Chu, S.W.; Curtis A.S. Nuclear Localization of HIV-1 Tat Functionalized Gold Nanoparticles. IEEE Trans. Nanobiosci., 2007, 6, 262-269.