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Volumn 211, Issue 3, 2012, Pages 257-265

Possible aryl hydrocarbon receptor-independent pathway of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced antiproliferative response in human breast cancer cells

Author keywords

3 Methylcholanthrene (3MC); Aryl hydrocarbon receptor (AhR); Dioxin; Estrogen receptor (ER); Polychlorinated biphenyl (PCB); Real Time Cell Analyzer

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DNA;

EID: 84860296339     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.04.005     Document Type: Article
Times cited : (26)

References (50)
  • 2
    • 0037764668 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells
    • Abdelrahim M., Smith R., Safe S. Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Molecular Pharmacology 2003, 63:1373-1381.
    • (2003) Molecular Pharmacology , vol.63 , pp. 1373-1381
    • Abdelrahim, M.1    Smith, R.2    Safe, S.3
  • 3
    • 0025666708 scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cell growth and the secretion of the estrogen-induced 34-, 52- and 160-kDa proteins in human breast cancer cells
    • Biegel L., Safe S. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cell growth and the secretion of the estrogen-induced 34-, 52- and 160-kDa proteins in human breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology 1990, 37:725-732.
    • (1990) Journal of Steroid Biochemistry and Molecular Biology , vol.37 , pp. 725-732
    • Biegel, L.1    Safe, S.2
  • 4
    • 33745965633 scopus 로고    scopus 로고
    • Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions
    • Bock K.W., Kohle C. Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions. Biochemical Pharmacology 2006, 72:393-404.
    • (2006) Biochemical Pharmacology , vol.72 , pp. 393-404
    • Bock, K.W.1    Kohle, C.2
  • 5
    • 0029893731 scopus 로고    scopus 로고
    • Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison
    • Cummings A.M., Metcalf J.L., Birnbaum L. Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison. Toxicology and Applied Pharmacology 1996, 138:131-139.
    • (1996) Toxicology and Applied Pharmacology , vol.138 , pp. 131-139
    • Cummings, A.M.1    Metcalf, J.L.2    Birnbaum, L.3
  • 7
    • 0028177952 scopus 로고
    • High passage T47D human breast cancer cells: altered endocrine and 2,3,7,8-tetrachlorodibenzo-p-dioxin responsiveness
    • Fernandez P., Burghardt R., Smith R., Nodland K., Safe S. High passage T47D human breast cancer cells: altered endocrine and 2,3,7,8-tetrachlorodibenzo-p-dioxin responsiveness. European Journal of Pharmacology 1994, 270:53-65.
    • (1994) European Journal of Pharmacology , vol.270 , pp. 53-65
    • Fernandez, P.1    Burghardt, R.2    Smith, R.3    Nodland, K.4    Safe, S.5
  • 8
    • 0026780139 scopus 로고
    • Growth inhibitory and antimitogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in T47D human breast cancer cells
    • Fernandez P., Safe S. Growth inhibitory and antimitogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in T47D human breast cancer cells. Toxicology Letters 1992, 61:185-197.
    • (1992) Toxicology Letters , vol.61 , pp. 185-197
    • Fernandez, P.1    Safe, S.2
  • 9
    • 33751166800 scopus 로고    scopus 로고
    • Stable knockdown of estrogen receptor α by vector-based RNA interference suppresses proliferation and enhances apoptosis in breast cancer cells
    • Fu H.J., Jia L.T., Bao W., Zhao J., Meng Y.L., Wang C.J., Yao L.B., Chen S.Y., Yang A.G. Stable knockdown of estrogen receptor α by vector-based RNA interference suppresses proliferation and enhances apoptosis in breast cancer cells. Cancer Biology and Therapy 2006, 5:842-847.
    • (2006) Cancer Biology and Therapy , vol.5 , pp. 842-847
    • Fu, H.J.1    Jia, L.T.2    Bao, W.3    Zhao, J.4    Meng, Y.L.5    Wang, C.J.6    Yao, L.B.7    Chen, S.Y.8    Yang, A.G.9
  • 10
    • 0027214018 scopus 로고
    • Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Bennett J.A., Bradley L.M., Cutler D.S. Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Research 1993, 53:3149-3153.
    • (1993) Cancer Research , vol.53 , pp. 3149-3153
    • Gierthy, J.F.1    Bennett, J.A.2    Bradley, L.M.3    Cutler, D.S.4
  • 11
    • 0024232945 scopus 로고
    • Inhibition of postconfluent focus production in cultures of MCF-7 human breast cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Lincoln D.W. Inhibition of postconfluent focus production in cultures of MCF-7 human breast cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Breast Cancer Research and Treatment 1988, 12:227-233.
    • (1988) Breast Cancer Research and Treatment , vol.12 , pp. 227-233
    • Gierthy, J.F.1    Lincoln, D.W.2
  • 12
    • 0023475365 scopus 로고
    • Suppression of estrogen-regulated extracellular tissue plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Lincoln D.W., Gillespie M.B., Seeger J.I., Martinez H.L., Dickerman H.W., Kumar S.A. Suppression of estrogen-regulated extracellular tissue plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Research 1987, 47:6198-6203.
    • (1987) Cancer Research , vol.47 , pp. 6198-6203
    • Gierthy, J.F.1    Lincoln, D.W.2    Gillespie, M.B.3    Seeger, J.I.4    Martinez, H.L.5    Dickerman, H.W.6    Kumar, S.A.7
  • 13
    • 0028122471 scopus 로고
    • Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists
    • Harper N., Wang X., Liu H., Safe S. Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists. Molecular and Cellular Endocrinology 1994, 104:47-55.
    • (1994) Molecular and Cellular Endocrinology , vol.104 , pp. 47-55
    • Harper, N.1    Wang, X.2    Liu, H.3    Safe, S.4
  • 15
    • 0028285283 scopus 로고
    • Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Holcomb M., Safe S. Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Letters 1994, 82:43-47.
    • (1994) Cancer Letters , vol.82 , pp. 43-47
    • Holcomb, M.1    Safe, S.2
  • 16
    • 0036935333 scopus 로고    scopus 로고
    • Altered protein profile and possible hypoxia in the placenta of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed rats
    • Ishimura R., Ohsako S., Kawakami T., Sakaue M., Aoki Y., Tohyama C. Altered protein profile and possible hypoxia in the placenta of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed rats. Toxicology and Applied Pharmacology 2002, 185:197-206.
    • (2002) Toxicology and Applied Pharmacology , vol.185 , pp. 197-206
    • Ishimura, R.1    Ohsako, S.2    Kawakami, T.3    Sakaue, M.4    Aoki, Y.5    Tohyama, C.6
  • 18
    • 0022602024 scopus 로고
    • Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues
    • Kimura S., Gonzalez F.J., Nebert D.W. Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues. Molecular and Cellular Biology 1986, 6:1471-1477.
    • (1986) Molecular and Cellular Biology , vol.6 , pp. 1471-1477
    • Kimura, S.1    Gonzalez, F.J.2    Nebert, D.W.3
  • 21
    • 0037026632 scopus 로고    scopus 로고
    • Increased aryl hydrocarbon receptor expression offers a potential therapeutic target in pancreatic cancer
    • Koliopanus A., Kleeff J., Xiao Y., Safe S., Zimmerman A., Buchler M.W., Friess H. Increased aryl hydrocarbon receptor expression offers a potential therapeutic target in pancreatic cancer. Oncogene 2002, 21:6059-6070.
    • (2002) Oncogene , vol.21 , pp. 6059-6070
    • Koliopanus, A.1    Kleeff, J.2    Xiao, Y.3    Safe, S.4    Zimmerman, A.5    Buchler, M.W.6    Friess, H.7
  • 22
    • 0028884592 scopus 로고
    • Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells
    • Krishnan V., Porter W., Santostefano M., Wang X., Safe S. Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells. Molecular and Cellular Biology 1995, 15:6710-6719.
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 6710-6719
    • Krishnan, V.1    Porter, W.2    Santostefano, M.3    Wang, X.4    Safe, S.5
  • 23
    • 0027335891 scopus 로고
    • Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships
    • Krishnan V., Safe S. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships. Toxicology and Applied Pharmacology 1993, 120:55-61.
    • (1993) Toxicology and Applied Pharmacology , vol.120 , pp. 55-61
    • Krishnan, V.1    Safe, S.2
  • 24
    • 33846827373 scopus 로고    scopus 로고
    • Endocrine therapy resistance can be associated with high estrogen receptor α (ERα) expression and reduced ERα phosphorylation in breast cancer models
    • Kuske B., Naughton C., Moore K., Macleod K.G., Miller W.R., Clarke R., Langdon S.P., Cameron D.A. Endocrine therapy resistance can be associated with high estrogen receptor α (ERα) expression and reduced ERα phosphorylation in breast cancer models. Endocrine-related Cancer 2006, 13:1121-1133.
    • (2006) Endocrine-related Cancer , vol.13 , pp. 1121-1133
    • Kuske, B.1    Naughton, C.2    Moore, K.3    Macleod, K.G.4    Miller, W.R.5    Clarke, R.6    Langdon, S.P.7    Cameron, D.A.8
  • 25
    • 69049092783 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation
    • Lew B.J., Collins L.L., O'Reilly M.A., Lawrence B.P. Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation. Toxicological Sciences 2009, 111:151-162.
    • (2009) Toxicological Sciences , vol.111 , pp. 151-162
    • Lew, B.J.1    Collins, L.L.2    O'Reilly, M.A.3    Lawrence, B.P.4
  • 26
    • 0026674353 scopus 로고
    • Inhibition of insulin-like growth factor-I responses in MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds
    • Liu H., Biegel L., Narasimhan T.R., Rowlands C., Safe S. Inhibition of insulin-like growth factor-I responses in MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Molecular and Cellular Endocrinology 1992, 87:19-28.
    • (1992) Molecular and Cellular Endocrinology , vol.87 , pp. 19-28
    • Liu, H.1    Biegel, L.2    Narasimhan, T.R.3    Rowlands, C.4    Safe, S.5
  • 27
    • 0030175873 scopus 로고    scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on insulin-induced responses in MCF-7 human breast cancer cells
    • Liu H., Safe S. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on insulin-induced responses in MCF-7 human breast cancer cells. Toxicology and Applied Pharmacology 1996, 138:242-250.
    • (1996) Toxicology and Applied Pharmacology , vol.138 , pp. 242-250
    • Liu, H.1    Safe, S.2
  • 29
    • 34347348554 scopus 로고    scopus 로고
    • Estrogen receptor and aryl hydrocarbon receptor signaling pathways
    • Matthews J., Gustafsson J.A. Estrogen receptor and aryl hydrocarbon receptor signaling pathways. Nucleic Receptor Signal 2006, 4:e016.
    • (2006) Nucleic Receptor Signal , vol.4
    • Matthews, J.1    Gustafsson, J.A.2
  • 30
    • 0035872466 scopus 로고    scopus 로고
    • Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective Ah receptor modulator
    • McDougal A., Wormke M., Calvin J., Safe S. Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective Ah receptor modulator. Cancer Research 2001, 61:3901-3907.
    • (2001) Cancer Research , vol.61 , pp. 3901-3907
    • McDougal, A.1    Wormke, M.2    Calvin, J.3    Safe, S.4
  • 32
    • 1542269170 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation
    • Morrow D., Qin C., Smith R., Safe S. Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation. Journal of Steroid Biochemistry and Molecular Biology 2004, 88:27-36.
    • (2004) Journal of Steroid Biochemistry and Molecular Biology , vol.88 , pp. 27-36
    • Morrow, D.1    Qin, C.2    Smith, R.3    Safe, S.4
  • 33
    • 33645131216 scopus 로고    scopus 로고
    • Organotin compounds enhance 17β-hydroxysteroid dehydrogenase type I activity in human choriocarcinoma JAr cells: potential promotion of 17β-estradiol biosynthesis in human placenta
    • Nakanishi T., Hiromori Y., Yokoyama H., Koyanagi M., Itoh N., Nishikawa J., Tanaka K. Organotin compounds enhance 17β-hydroxysteroid dehydrogenase type I activity in human choriocarcinoma JAr cells: potential promotion of 17β-estradiol biosynthesis in human placenta. Biochemical Pharmacology 2006, 71:1349-1357.
    • (2006) Biochemical Pharmacology , vol.71 , pp. 1349-1357
    • Nakanishi, T.1    Hiromori, Y.2    Yokoyama, H.3    Koyanagi, M.4    Itoh, N.5    Nishikawa, J.6    Tanaka, K.7
  • 36
    • 4744375490 scopus 로고    scopus 로고
    • TCDD and PCBs inhibit breast cancer cell proliferation in vitro
    • Oenga G.N., Spink D.C., Carpenter D.O. TCDD and PCBs inhibit breast cancer cell proliferation in vitro. Toxicological In Vitro 2004, 18:811-819.
    • (2004) Toxicological In Vitro , vol.18 , pp. 811-819
    • Oenga, G.N.1    Spink, D.C.2    Carpenter, D.O.3
  • 39
    • 34447530842 scopus 로고    scopus 로고
    • An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI
    • Okey A.B. An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicological Sciences 2007, 98:5-38.
    • (2007) Toxicological Sciences , vol.98 , pp. 5-38
    • Okey, A.B.1
  • 40
    • 30344473144 scopus 로고    scopus 로고
    • Pharmacokinetics of ovarian steroids in Sprague-Dawley rats after acute exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Petroff B.K., Mizinga K.M. Pharmacokinetics of ovarian steroids in Sprague-Dawley rats after acute exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Reproductive Biology 2003, 3:131-141.
    • (2003) Reproductive Biology , vol.3 , pp. 131-141
    • Petroff, B.K.1    Mizinga, K.M.2
  • 41
    • 0034723264 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest
    • Puga A., Barnes S.J., Dalton T.P., Chang C., Knudsen E.S., Maier M.A. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. Journal of Biological Chemistry 2000, 275:2943-2950.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 2943-2950
    • Puga, A.1    Barnes, S.J.2    Dalton, T.P.3    Chang, C.4    Knudsen, E.S.5    Maier, M.A.6
  • 42
    • 0032897801 scopus 로고    scopus 로고
    • 3,3',4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary cells and in human breast cancer cells
    • Ramamoorthy K., Gupta M.S., Sun G., McDougal A., Safe S.H. 3,3',4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary cells and in human breast cancer cells. Carcinogenesis 1999, 20:115-123.
    • (1999) Carcinogenesis , vol.20 , pp. 115-123
    • Ramamoorthy, K.1    Gupta, M.S.2    Sun, G.3    McDougal, A.4    Safe, S.H.5
  • 43
    • 0034485357 scopus 로고    scopus 로고
    • Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells
    • Safe S., Wormke M., Samudio I. Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. Journal of Mammary Gland Biology and Neoplasia 2000, 5:295-306.
    • (2000) Journal of Mammary Gland Biology and Neoplasia , vol.5 , pp. 295-306
    • Safe, S.1    Wormke, M.2    Samudio, I.3
  • 44
    • 0029118684 scopus 로고
    • Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds
    • Safe S.H. Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Pharmacology & Therapeutics 1995, 67:247-281.
    • (1995) Pharmacology & Therapeutics , vol.67 , pp. 247-281
    • Safe, S.H.1
  • 46
    • 0031426303 scopus 로고    scopus 로고
    • Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Wang W.L., Porter W., Burghardt R., Safe S.H. Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Carcinogenesis 1997, 18:925-933.
    • (1997) Carcinogenesis , vol.18 , pp. 925-933
    • Wang, W.L.1    Porter, W.2    Burghardt, R.3    Safe, S.H.4
  • 49
    • 0028285855 scopus 로고
    • Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17β-estradiol-induced pS2 expression
    • Zacharewski T.R., Bondy K.L., McDonell P., Wu Z.F. Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17β-estradiol-induced pS2 expression. Cancer Research 1994, 54:2707-2713.
    • (1994) Cancer Research , vol.54 , pp. 2707-2713
    • Zacharewski, T.R.1    Bondy, K.L.2    McDonell, P.3    Wu, Z.F.4
  • 50
    • 72749083607 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy
    • Zhang S., Lei P., Liu X., Li X., Walker K., Kotha L., Rowlands C., Safe S. The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy. Endocrine-related Cancer 2009, 16:835-844.
    • (2009) Endocrine-related Cancer , vol.16 , pp. 835-844
    • Zhang, S.1    Lei, P.2    Liu, X.3    Li, X.4    Walker, K.5    Kotha, L.6    Rowlands, C.7    Safe, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.