-
1
-
-
35548943647
-
Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis
-
Aerbajinai W., Zhu J., Gao Z., Chin K., Rodgers G.P. Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis. Blood 2007, 110:2864-2871.
-
(2007)
Blood
, vol.110
, pp. 2864-2871
-
-
Aerbajinai, W.1
Zhu, J.2
Gao, Z.3
Chin, K.4
Rodgers, G.P.5
-
2
-
-
33746531759
-
Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins
-
Anfosso L., Efferth T., Albini A., Pfeffer U. Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins. Pharmacogenomics J. 2006, 6:269-278.
-
(2006)
Pharmacogenomics J.
, vol.6
, pp. 269-278
-
-
Anfosso, L.1
Efferth, T.2
Albini, A.3
Pfeffer, U.4
-
3
-
-
0021254508
-
Embryotoxicity and teratogenicity studies on artemether in mice, rats and rabbits
-
Chen L.J., Wang M.Y., Sun W.K., Liu M.Z. Embryotoxicity and teratogenicity studies on artemether in mice, rats and rabbits. Zhongguo yao li xue bao 1984, 5:118-122.
-
(1984)
Zhongguo yao li xue bao
, vol.5
, pp. 118-122
-
-
Chen, L.J.1
Wang, M.Y.2
Sun, W.K.3
Liu, M.Z.4
-
4
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987, 162:156-159.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
5
-
-
51449116958
-
Artesunate: developmental toxicity and toxicokinetics in monkeys
-
Clark R.L., Arima A., Makori N., Nakata Y., Bernard F., Gristwood W., Harrell A., White T.E., Wier P.J. Artesunate: developmental toxicity and toxicokinetics in monkeys. Birth Defects Res. 2008, 83:418-434.
-
(2008)
Birth Defects Res.
, vol.83
, pp. 418-434
-
-
Clark, R.L.1
Arima, A.2
Makori, N.3
Nakata, Y.4
Bernard, F.5
Gristwood, W.6
Harrell, A.7
White, T.E.8
Wier, P.J.9
-
6
-
-
51449116532
-
Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count
-
Clark R.L., Lerman S.A., Cox E.M., Gristwood W.E., White T.E. Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count. Birth Defects Res. 2008, 83:397-406.
-
(2008)
Birth Defects Res.
, vol.83
, pp. 397-406
-
-
Clark, R.L.1
Lerman, S.A.2
Cox, E.M.3
Gristwood, W.E.4
White, T.E.5
-
7
-
-
11344258568
-
Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit
-
Clark R.L., White T.E.S.A.C., Gaunt I., Winstanley P., Ward S.A. Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit. Birth Defects Res. 2004, 71:380-394.
-
(2004)
Birth Defects Res.
, vol.71
, pp. 380-394
-
-
Clark, R.L.1
White, T.E.S.A.C.2
Gaunt, I.3
Winstanley, P.4
Ward, S.A.5
-
8
-
-
35348978361
-
Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity
-
D'Alessandro S., Gelati M., Basilico N., Parati E.A., Haynes R.K., Taramelli D. Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity. Toxicology 2007, 241:66-74.
-
(2007)
Toxicology
, vol.241
, pp. 66-74
-
-
D'Alessandro, S.1
Gelati, M.2
Basilico, N.3
Parati, E.A.4
Haynes, R.K.5
Taramelli, D.6
-
9
-
-
20444365167
-
Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy
-
Efferth T. Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy. Drug Resist. Updat. 2005, 8:85-97.
-
(2005)
Drug Resist. Updat.
, vol.8
, pp. 85-97
-
-
Efferth, T.1
-
10
-
-
34250344275
-
Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin-from bench to bedside
-
Efferth T. Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin-from bench to bedside. Planta Med. 2007, 73:299-309.
-
(2007)
Planta Med.
, vol.73
, pp. 299-309
-
-
Efferth, T.1
-
11
-
-
0032407144
-
Techniques for studying stimulation of fetal hemoglobin production in human erythroid cultures
-
Fibach E. Techniques for studying stimulation of fetal hemoglobin production in human erythroid cultures. Hemoglobin 1998, 22:445-458.
-
(1998)
Hemoglobin
, vol.22
, pp. 445-458
-
-
Fibach, E.1
-
12
-
-
0024581574
-
Proliferation and maturation of human erythroid progenitors in liquid culture
-
Fibach E., Manor D., Oppenheim A., Rachmilewitz E.A. Proliferation and maturation of human erythroid progenitors in liquid culture. Blood 1989, 73:100-103.
-
(1989)
Blood
, vol.73
, pp. 100-103
-
-
Fibach, E.1
Manor, D.2
Oppenheim, A.3
Rachmilewitz, E.A.4
-
14
-
-
75749097693
-
Severe embryotoxicity of artemisinin derivatives in experimental animals, but possibly safe in pregnant women
-
Li Q., Weina P.J. Severe embryotoxicity of artemisinin derivatives in experimental animals, but possibly safe in pregnant women. Molecules 2010, 15:40-57.
-
(2010)
Molecules
, vol.15
, pp. 40-57
-
-
Li, Q.1
Weina, P.J.2
-
15
-
-
48949116218
-
Investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) using the Frog Embryo Teratogenesis Assay-Xenopus (FETAX)
-
Longo M., Zanoncelli S., Della Torre P., Rosa F., Giusti A., Colombo P., Brughera M., Mazue G., Olliaro P. Investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) using the Frog Embryo Teratogenesis Assay-Xenopus (FETAX). Reprod. Toxicol. 2008, 25:433-441.
-
(2008)
Reprod. Toxicol.
, vol.25
, pp. 433-441
-
-
Longo, M.1
Zanoncelli, S.2
Della Torre, P.3
Rosa, F.4
Giusti, A.5
Colombo, P.6
Brughera, M.7
Mazue, G.8
Olliaro, P.9
-
16
-
-
30044436035
-
Effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos in vitro
-
Longo M., Zanoncelli S., Manera D., Brughera M., Colombo P., Lansen J., Mazue G., Gomes M., Taylor W.R.J., Olliaro P. Effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos in vitro. Reprod. Toxicol. 2006, 21:83-93.
-
(2006)
Reprod. Toxicol.
, vol.21
, pp. 83-93
-
-
Longo, M.1
Zanoncelli, S.2
Manera, D.3
Brughera, M.4
Colombo, P.5
Lansen, J.6
Mazue, G.7
Gomes, M.8
Taylor, W.R.J.9
Olliaro, P.10
-
17
-
-
33750007435
-
In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos
-
Longo M., Zanoncelli S., Torre P.D., Riflettuto M., Cocco F., Pesenti M., Giusti A., Colombo P., Brughera M., Mazue G., Navaratman V., Gomes M., Olliaro P. In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos. Reprod. Toxicol. 2006, 22:797-810.
-
(2006)
Reprod. Toxicol.
, vol.22
, pp. 797-810
-
-
Longo, M.1
Zanoncelli, S.2
Torre, P.D.3
Riflettuto, M.4
Cocco, F.5
Pesenti, M.6
Giusti, A.7
Colombo, P.8
Brughera, M.9
Mazue, G.10
Navaratman, V.11
Gomes, M.12
Olliaro, P.13
-
18
-
-
33751253121
-
The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria
-
McGready R., Stepniewska K., Lindegardh N., Ashley E.A., La Y., Singhasivanon P., White N.J., Nosten F. The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria. Eur. J. Clin. Pharmacol. 2006, 62:1021-1031.
-
(2006)
Eur. J. Clin. Pharmacol.
, vol.62
, pp. 1021-1031
-
-
McGready, R.1
Stepniewska, K.2
Lindegardh, N.3
Ashley, E.A.4
La, Y.5
Singhasivanon, P.6
White, N.J.7
Nosten, F.8
-
19
-
-
33646536090
-
Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria
-
McGready R., Stepniewska K., Ward S.A., Cho T., Gilveray G., Looareesuwan S., White N.J., Nosten F. Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria. Eur. J. Clin. Pharmacol. 2006, 62:367-371.
-
(2006)
Eur. J. Clin. Pharmacol.
, vol.62
, pp. 367-371
-
-
McGready, R.1
Stepniewska, K.2
Ward, S.A.3
Cho, T.4
Gilveray, G.5
Looareesuwan, S.6
White, N.J.7
Nosten, F.8
-
20
-
-
33846317129
-
Reducing the burden of malaria in pregnancy by preventive strategies
-
Menendez C., D'Alessandro U., ter Kuile F.O. Reducing the burden of malaria in pregnancy by preventive strategies. Lancet Infect. Dis. 2007, 7:126-135.
-
(2007)
Lancet Infect. Dis.
, vol.7
, pp. 126-135
-
-
Menendez, C.1
D'Alessandro, U.2
ter Kuile, F.O.3
-
21
-
-
58449099020
-
The role of bioactivation in the pharmacology and toxicology of the artemisinin-based antimalarials
-
Mercer A.E. The role of bioactivation in the pharmacology and toxicology of the artemisinin-based antimalarials. Curr. Opin. Drug Discov. Devel. 2009, 12:125-132.
-
(2009)
Curr. Opin. Drug Discov. Devel.
, vol.12
, pp. 125-132
-
-
Mercer, A.E.1
-
22
-
-
0029894037
-
Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy
-
Meshnick S.R., Taylor T.E., Kamchonwongpaisan S. Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy. Microbiol. Rev. 1996, 60:301-315.
-
(1996)
Microbiol. Rev.
, vol.60
, pp. 301-315
-
-
Meshnick, S.R.1
Taylor, T.E.2
Kamchonwongpaisan, S.3
-
23
-
-
38149059827
-
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells
-
Moutouh-de Parseval L.A., Verhelle D., Glezer E., Jensen-Pergakes K., Ferguson G.D., Corral L.G., Morris C.L., Muller G., Brady H., Chan K. Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells. J. Clin. Invest. 2008, 118:248-258.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 248-258
-
-
Moutouh-de Parseval, L.A.1
Verhelle, D.2
Glezer, E.3
Jensen-Pergakes, K.4
Ferguson, G.D.5
Corral, L.G.6
Morris, C.L.7
Muller, G.8
Brady, H.9
Chan, K.10
-
24
-
-
0036251289
-
Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo
-
Neildez-Nguyen T.M., Wajcman H., Marden M.C., Bensidhoum M., Moncollin V., Giarratana M.C., Kobari L., Thierry D., Douay L. Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo. Nat. Biotechnol. 2002, 20:467-472.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 467-472
-
-
Neildez-Nguyen, T.M.1
Wajcman, H.2
Marden, M.C.3
Bensidhoum, M.4
Moncollin, V.5
Giarratana, M.C.6
Kobari, L.7
Thierry, D.8
Douay, L.9
-
25
-
-
33749519678
-
Antimalarial drugs in pregnancy: a review
-
Nosten F., McGready R., d'Alessandro U., Bonell A., Verhoeff F., Menendez C., Mutabingwa T., Brabin B. Antimalarial drugs in pregnancy: a review. Curr. Drug Saf. 2006, 1:1-15.
-
(2006)
Curr. Drug Saf.
, vol.1
, pp. 1-15
-
-
Nosten, F.1
McGready, R.2
d'Alessandro, U.3
Bonell, A.4
Verhoeff, F.5
Menendez, C.6
Mutabingwa, T.7
Brabin, B.8
-
26
-
-
41949100415
-
Ontogeny of erythropoiesis
-
Palis J. Ontogeny of erythropoiesis. Curr. Opin. Hematol. 2008, 15:155-161.
-
(2008)
Curr. Opin. Hematol.
, vol.15
, pp. 155-161
-
-
Palis, J.1
-
27
-
-
0034909083
-
Yolk-sac hematopoiesis: the first blood cells of mouse and man
-
Palis J., Yoder M.C. Yolk-sac hematopoiesis: the first blood cells of mouse and man. Exp. Hematol. 2001, 29:927-936.
-
(2001)
Exp. Hematol.
, vol.29
, pp. 927-936
-
-
Palis, J.1
Yoder, M.C.2
-
28
-
-
4544318700
-
Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin
-
Parapini S., Basilico N., Mondani M., Olliaro P., Taramelli D., Monti D. Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin. FEBS Lett. 2004, 575:91-94.
-
(2004)
FEBS Lett.
, vol.575
, pp. 91-94
-
-
Parapini, S.1
Basilico, N.2
Mondani, M.3
Olliaro, P.4
Taramelli, D.5
Monti, D.6
-
29
-
-
0006899513
-
Safety of artemisinin and its derivatives. A review of published and unpublished clinical trials
-
Ribeiro I.R., Olliaro P. Safety of artemisinin and its derivatives. A review of published and unpublished clinical trials. Med. Trop. (Mars) 1998, 58:50-53.
-
(1998)
Med. Trop. (Mars)
, vol.58
, pp. 50-53
-
-
Ribeiro, I.R.1
Olliaro, P.2
-
30
-
-
0036009409
-
From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs
-
Robert A., Dechy-Cabaret O., Cazelles J., Meunier B. From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs. Acc. Chem. Res. 2002, 35:167-174.
-
(2002)
Acc. Chem. Res.
, vol.35
, pp. 167-174
-
-
Robert, A.1
Dechy-Cabaret, O.2
Cazelles, J.3
Meunier, B.4
-
31
-
-
38949133445
-
Erythroid differentiation and maturation from peripheral CD34+ cells in liquid culture: cellular and molecular characterization
-
Ronzoni L., Bonara P., Rusconi D., Frugoni C., Libani I., Cappellini M.D. Erythroid differentiation and maturation from peripheral CD34+ cells in liquid culture: cellular and molecular characterization. Blood Cells Mol. Dis. 2008, 40:148-155.
-
(2008)
Blood Cells Mol. Dis.
, vol.40
, pp. 148-155
-
-
Ronzoni, L.1
Bonara, P.2
Rusconi, D.3
Frugoni, C.4
Libani, I.5
Cappellini, M.D.6
-
32
-
-
34548293148
-
Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs
-
Stocks P.A., Bray P.G., Barton V.E., Al-Helal M., Jones M., Araujo N.C., Gibbons P., Ward S.A., Hughes R.H., Biagini G.A., Davies J., Amewu R., Mercer A.E., Ellis G., O'Neill P.M. Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs. Angew. Chem. Int. Ed. Engl. 2007, 46:6278-6283.
-
(2007)
Angew. Chem. Int. Ed. Engl.
, vol.46
, pp. 6278-6283
-
-
Stocks, P.A.1
Bray, P.G.2
Barton, V.E.3
Al-Helal, M.4
Jones, M.5
Araujo, N.C.6
Gibbons, P.7
Ward, S.A.8
Hughes, R.H.9
Biagini, G.A.10
Davies, J.11
Amewu, R.12
Mercer, A.E.13
Ellis, G.14
O'Neill, P.M.15
-
33
-
-
0030856294
-
Hemopoiesis in human fetal and embryonic liver
-
Timens W., Kamps W.A. Hemopoiesis in human fetal and embryonic liver. Microsc. Res. Tech. 1997, 39:387-397.
-
(1997)
Microsc. Res. Tech.
, vol.39
, pp. 387-397
-
-
Timens, W.1
Kamps, W.A.2
-
34
-
-
77949661216
-
Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation
-
Wang J., Huang L., Li J., Fan Q., Long Y., Li Y., Zhou B. Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation. PLoS One 2010, 5:e9582.
-
(2010)
PLoS One
, vol.5
-
-
Wang, J.1
Huang, L.2
Li, J.3
Fan, Q.4
Long, Y.5
Li, Y.6
Zhou, B.7
-
35
-
-
33846314664
-
Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance
-
Ward S.A., Sevene E.J., Hastings I.M., Nosten F., McGready R. Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance. Lancet Infect. Dis. 2007, 7:136-144.
-
(2007)
Lancet Infect. Dis.
, vol.7
, pp. 136-144
-
-
Ward, S.A.1
Sevene, E.J.2
Hastings, I.M.3
Nosten, F.4
McGready, R.5
-
36
-
-
33750445619
-
Artesunate-induced depletion of embryonic erythroblasts precedes embryolethality and teratogenicity in vivo
-
White T.E., Bushdid P.B., Ritter S., Laffan S.B., Clark R.L. Artesunate-induced depletion of embryonic erythroblasts precedes embryolethality and teratogenicity in vivo. Birth Defects Res. 2006, 77:413-429.
-
(2006)
Birth Defects Res.
, vol.77
, pp. 413-429
-
-
White, T.E.1
Bushdid, P.B.2
Ritter, S.3
Laffan, S.B.4
Clark, R.L.5
-
37
-
-
51449124524
-
Sensitive periods for developmental toxicity of orally administered artesunate in the rat
-
White T.E., Clark R.L. Sensitive periods for developmental toxicity of orally administered artesunate in the rat. Birth Defects Res. 2008, 83:407-417.
-
(2008)
Birth Defects Res.
, vol.83
, pp. 407-417
-
-
White, T.E.1
Clark, R.L.2
|