Combination of Low-Dose Bupivacaine and Opioids Provides Satisfactory Analgesia with Less Intraoperative Hypotension for Spinal Anesthesia in Cesarean Section

CNS Neuroscience and Therapeutics

Volumn 18, Issue 5, 2012, Pages 426-432

  Qiu, Man Tang ^a,b   Lin, Fu Qing ^a   Fu, Shu Kun ^a   Zhang, Heng Bin ^a,b   Li, Hui Hua ^c   Zhang, Li Ming ^c   Li, Quan ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Bupivacaine; Cesarean section; Hypotension; Opioids; Spinal anesthesia

Indexed keywords

BUPIVACAINE; EPHEDRINE; FENTANYL; PETHIDINE; SUFENTANIL;

ANALGESIA; ARTICLE; CESAREAN SECTION; COCHRANE LIBRARY; DRUG MEGADOSE; EMBASE; HUMAN; HYPOTENSION; INCIDENCE; INTRAOPERATIVE PERIOD; LOW DRUG DOSE; MEDLINE; META ANALYSIS; POSTOPERATIVE NAUSEA; POSTOPERATIVE VOMITING; PRURITUS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RELIABILITY; SHIVERING; SPINAL ANESTHESIA;

ANALGESIA, OBSTETRICAL; ANALGESICS, OPIOID; ANESTHESIA, SPINAL; BUPIVACAINE; DATABASES, BIBLIOGRAPHIC; FEMALE; HUMANS; HYPERTENSION; POSTOPERATIVE COMPLICATIONS;

EID: 84860287208     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/j.1755-5949.2012.00306.x     Document Type: Article

References (27)

1. Fan SZ, Susetio L, Wang YP, Cheng YJ, Liu CC. Low dose of intrathecal hyperbaric bupivacaine combined with epidural lidocaine for cesarean section: A balance block technique. Anesth Analg 1994;78:474-477.
2. Yu SC, Ngan Kee WD, Kwan AS. Addition of meperidine to bupivacaine for spinal anesthesia for Cesarean section. Br J Anaesth 2002;33:379-383.
3. Rout CC, Rocke DA. Prevention of hypotension following spinal anesthesia for cesarean section. Int Anesthesiol Clin 1994;32:117-135.
4. Kansal A, Mohta M, Sethi AK, Tyagi A, Kumar P. Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anesthesia for caesarean section. Anesthesia 2005;60:28-34.
5. Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology 2002;97:1582-1590.
6. Kang FC, Tsai YC, Chang PJ, Chen TS. Subarachnoid fentanyl with diluted small-dose bupivacaine for cesarean section delivery. Acta Anaesthesiol Sin 1998;36:207-214.
7. Roofthooft E, Van de Velde M. Low-dose spinal anesthesia for Caesarean section to prevent spinal-induced hypotension. Curr Opin Anaesthesiol 2008;21:259-262.
8. Dahlgren G, Hultstrand C, Jakobsson J, Norman M, Errikson EW, Martin H. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for cesarean section. Anesth Analg 1997;85:1288-1293.
9. Hunt CO, Naulty S, Bader AM, et al. Perioperative analgesia with subarachnoid fentanyl-bupivacaine for cesarean delivery. Anesthesiology 1989;71:535-540.
10. Ng K, Parsons J, Cyna AM, Middleton P. Spinal versus epidural anesthesia for caesarean section. Cochrane Database Syst Rev 2004;2:CD003765
11. Turhanoglu S, Kaya S, Erdogan H. Is there an advantage in using low-dose intrathecal bupivacaine for cesarean section? J Anesth 2009;23:353-357.
12. Kiran S, Singal NK. A comparative study of three different doses of 0.5% hyperbaric bupivacaine for spinal anesthesia in elective caesarean section. Int J Obstet Anesth 2002;11:185-189.
13. Ben-David B, Miller G, Gavriel R, Gurevitch A. Low-dose bupivacaine-fentanyl spinal anesthesia for cesarean delivery. Reg Anesth Pain Med 2000;25:235-239.
14. Atalay C, Aksoy M, Aksoy AN, Dogan N, KÜrasd H. Combining intrathecal bupivacaine and meperidine during caesarean section to prevent spinal anesthesia-induced hypotension and other side-effects. J Int Med Res 2010;38:1626-1636.
15. Benhamou D, Wong C. Neuraxial anesthesia for cesarean delivery: What criteria define the "optimal" technique? Anesth Analg 2009;109:1370-1373.
16. Agrawal A, Agrawal S, Asthana V, Payal YS, Sharam J, Gupta V. Comparison of intrathecal fentanyl and sufentanil in addition to bupivacaine for caesarean section under spinal anesthesia. J of Anaesth Clin Pharma 2009;25:154-156.
17. Tolia G, Kumar A, Jain A, Pandey M. Low dose intrathecal bupivacaine with fentanyl for cesarean delivery. J of Anaesth Clin Pharma 2008;24:201-204.
18. Sivevski A. Spinal anesthesia for cesarean section with reduced dose of intrathecal bupivacaine plus fentanyl. Prilozi 2006;27:225-236.
19. Chung CJ, Bae SH, Chae KY, Chin YJ. Spinal anesthesia with 0.25% hyperbaric bupivacaine for Caesarean section: Effects of volume. Br J Anaesth 1996;77:145-149.
20. Thorén T, Holmström B, Rawal N, Schollin J, Lindeberg C, Skeppner G. Sequential combined spinal epidural block versus spinal block for cesarean section: Effects on maternal hypotension and neurobehavioral function of the newborn. Anesth Analg 1994;78:1087-1092.
21. Pedersen H, Santos AC, Steinberg ES, Schapiro HM, Harmon TW, Finster M. Incidence of visceral pain during cesarean section: The effect of varying doses of spinal bupivacaine. Anesth Analg 1989;69:46-49.
22. Seyedhejazi M, Madarek E. The effect of small dose bupivacaine-fentanyl in spinal anesthesia on hemodynamic nausea and vomiting in cesarean section. Pak J Med Sci 2007;23:747-750.
23. Gunusen I, Karaman S, Sargin A, Firat V. A randomized comparison of different doses of intrathecal levobupivacaine combined with fentanyl for elective cesarean section: Prospective, double-blinded study. J Anesth 2011;25:205-212.
24. Kafle SK. Intrathecal meperidine for elective Caesarean section: A comparison with lidocaine. Can J Anaesth 1993;40:718-721.
25. Lui AC, Polis TZ, Cicutti NJ. Densities of cerebrospinal fluid and spinal anaesthetic solutions in surgical patients at body temperature. Can J Anaesth 1998;45:297-303.
26. Balki M, Carvalho JC. Intraoperative nausea and vomiting during cesarean section under regional anesthesia. Int J Obstet Anesth 2005;14:230-241.
27. Klöhr S, Roth R, Hofmann T, Rossaint R, Heesen M. Definitions of hypotension after spinal anesthesia for caesarean section: Literature search and application to parturients. Acta Anaesthesiol Scand 2010;54:909-921.