Randomised trial of intravenous infusion of ephedrine or mephentermine for management of hypotension during spinal anaesthesia for Caesarean section

Anaesthesia

Volumn 60, Issue 1, 2005, Pages 28-34

  Kansal, A ^a   Mohta, Medha ^a   Sethi, A K ^a   Tyagi, A ^a   Kumar, P ^a  

^a UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; DOBUTAMINE; DOPAMINE; EPHEDRINE; HYPERTENSIVE AGENT; MEPHENTERMINE; METARAMINOL; METHOXAMINE; PHENYLEPHRINE;

ACID BASE BALANCE; ACIDOSIS; ADULT; ANGINA PECTORIS; APGAR SCORE; ARTERIAL PRESSURE; ARTICLE; BRADYCARDIA; CESAREAN SECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE DURATION; DIZZINESS; DRUG INFUSION; ECG ABNORMALITY; ELECTIVE SURGERY; FEMALE; HEADACHE; HEART VENTRICLE EXTRASYSTOLE; HEMODYNAMIC PARAMETERS; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; NAUSEA AND VOMITING; PREGNANT WOMAN; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; RR INTERVAL; SPINAL ANESTHESIA; STATISTICAL ANALYSIS; SYSTOLIC BLOOD PRESSURE; TITRIMETRY;

ADRENERGIC AGENTS; ADULT; ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; APGAR SCORE; CESAREAN SECTION; DOUBLE-BLIND METHOD; EPHEDRINE; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; HYPOTENSION; INFUSIONS, INTRAVENOUS; MEPHENTERMINE; PREGNANCY; PREGNANCY OUTCOME; VASOCONSTRICTOR AGENTS;

EID: 11444261265     PISSN: 00032409     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2044.2004.03994.x     Document Type: Article

References (34)

1. Rout CC, Rocke DA. Prevention of hypotension following spinal anesthesia for cesarean section. International Anesthesiology Clinics 1994; 32: 117-35.
2. Roberts SW, Leveno KJ, Sidawi JE, Lucas MJ, Kelly MA, Fetal acidemia associated with regional anesthesia for elective cesarean delivery. Obstetrics and Gynecology 1995; 85: 79-83.
3. Robson SC, Boys RJ, Rodeck C, Morgan B. Maternal and fetal haemodynamic effects of spinal and extradural anaesthesia for elective caesarean section. British Journal of Anaesthesia 1992; 68: 54-9.
4. Wright RG, Shnider SM. Hypotension and regional anesthesia. In: Shnider SM, Levinson G, eds. Anesthesia for Obstetrics, 3rd edn. Baltimore: Williams & Wilkins, 1993: 397-406.
5. Sharma SK, Gajraj NM, Sidawi JE. Prevention of hypotension during spinal anesthesia: a comparison of intravascular administration of hetastarch versus lactated Ringer's solution. Anesthesia and Analgesia 1997; 84: 111-4.
6. Clark RB, Thompson DS, Thompson CH. Prevention of spinal hypotension associated with cesarean section. Anesthesiology 1976; 45: 670-4.
7. Kang YG, Abouleish E, Caritis S. Prophylactic intravenous ephedrine infusion during spinal anesthesia for cesarean section. Anesthesia and Analgesia 1982; 61: 839-42.
8. Thomas DG, Robson SC, Redfern N, Hughes D, Boys RJ. Randomized trial of bolus phenylephrine or ephedrine for maintenance of arterial pressure during spinal anaesthesia for caesarean section. British Journal of Anaesthesia 1996; 76: 61-5.
9. Ramin SM, Ramin KD, Cox K, Magness RR, Shearer VE, Gant NF. Comparison of prophylactic angiotensin II versus ephedrine infusion for prevention of maternal hypotension during spinal anesthesia. American Journal of Obstetrics and Gynecology 1994; 171: 734-9.
10. Ngan Kee WD, Lau TK, Khaw KS, Lee BB. A comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section. Anesthesiology 2001; 95: 307-13.
11. Stoelting RK. Sympathomimetics. In: Stoelting RK, ed. Pharmacology and Physiology in Anesthetic Practice, 3rd edn. Philadelphia: Lippincott-Raven, 1999: 259-77.
12. Burns SM, Cowan CM, Wilkes RG. Prevention and management of hypotension during spinal anaesthesia for elective Caesarean section: a survey of practice. Anaesthesia 2001; 56: 794-8.
13. Shearer VE, Ramin SM, Wallace DH, Dax JS, Gilstrap LC III. Fetal effects of prophylactic ephedrine and maternal hypotension during regional anesthesia for cesarean section. Journal of Maternal and Fetal Medicine 1996; 5: 79-84.
14. Hoffman BB. Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In: Hardman JG, Limbird LE, Gilman AG, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 10th edn. New Delhi: McGraw-Hill, 2001: 215-68.
15. Hodge RL, Dornhorst AC. Clinical pharmacology of vasoconstrictors. Clinical Pharmacology and Therapeutics 1966; 7 639-47.
16. Li TH, Shimosato S, Gamble CA, Etsten BE. Hemodynamics of mephentermine during spinal anesthesia in man. Anesthesiology 1963; 24: 817-27.
17. Sahu D, Kothari D, Mehrotra A. Comparison of bolus phenylephrine, ephedrine and mephentermine for maintenance of arterial pressure during spinal anaesthesia in caesarean section - a clinical study. Indian Journal of Anaesthesia 2003; 47: 125-8.
18. 2 and bicarbonate following uncomplicated term vaginal deliveries. American Journal of Obstetrics and Gynecology 1985; 151: 798-800.
19. Crawford JS. Caesarean section. In: Crawford JS, ed. Principles and Practice of Obstetric Anaesthesia, 4th edn. Oxford: Blackwell Scientific Publications, 1978: 243-84.
20. Park GE, Hauch MA, Curlin F, Datta S, Bader AM. The effects of varying volumes of crystalloid administration before Cesarean delivery on maternal hemodynamics and colloid osmotic pressure. Anesthesia and Analgesia 1996; 83: 299-303.
21. Hon EH, Reid BL, Hehre FW. The electronic evaluation of fetal heart rate. II. Changes with maternal hypotension. American Journal of Obstetrics and Gynecology 1960; 79: 209-15.
22. Corke BC, Datta S, Ostheimer GW, Weiss JB, Alper MH. Spinal anaesthesia for caesarean section. The influence of hypotension on neonatal outcome. Anaesthesia 1982; 37: 658-62.
23. Thorp JA, Rushing RS. Umbilical cord blood gas analysis. Obstetrics and Gynecology Clinics of North America 1999; 26: 695-709.
24. Ramin SM, Gilstrap LC III, Leveno KJ, Burris J, Little BB. Umbilical artery acid-base status in the preterm infant. Obstetrics and Gynecology 1989; 74: 256-8.
25. Jouppila P, Jouppila R, Barinoff T, Koivula A. Placental blood flow during caesarean section performed under subarachnoid blockade. British Journal of Anaesthesia 1984; 56: 1379-83.
26. Greiss F Jr. Concepts of Uterine Blood Flow. In: Wynn RM, ed. Obstetrics and Gynecology Annual. New York: Appelton, Century-Crofts, 1973: 55-83.
27. Defalque RJ. Compared effects of spinal and extradural anesthesia upon the blood pressure. Anesthesiology 1962; 23: 627-30.
28. Loughrey JPR, Walsh F, Gardiner J. Prophylactic intravenous bolus ephedrine for elective caesarean section under spinal anaesthesia. European Journal of Anaesthesiology 2002; 19: 63-8.
29. Morgan P. The role of vasopressors in the management of hypotension induced by spinal and epidural anaesthesia. Canadian Journal of Anaesthesia 1994; 41: 404-13.
30. Rolbin SH, Cole AF, Hew EM, Pollard A, Virgint S. Prophylactic intramuscular ephedrine before epidural anaesthesia for caesarean section. efficacy and actions on the fetus and newborn. Canadian Anaesthesia Society Journal 1982; 29: 148-53.
31. Pel M, Treffers PE. The reliability of the result of the umbilical cord pH. Journal of Perinatal Medicine 1983; 11: 169-74.
32. Ngan Kee WD, Lee A. Multivariate analysis of factors associated with umbilical arterial pH and standard base excess after caesarean section under spinal anaesthesia. Anaesthesia 2003; 58 125-30.
33. Mercier FJ, Piley ET, Frederickson WL, Roger-Christoph S, Benhamou D, Cohen SE. Phenylephrine added to prophylactic ephedrine infusion during spinal anesthesia for elective cesarean section. Anesthesiology 2001; 95: 668-74.
34. Casey BM, McIntire DD, Leveno KJ. The continuing value of the APGAR score for the assessment of newborn infants. New England Journal of Medicine 2001; 344: 467-71.