Hypoxia and TP53 deficiency for induced pluripotent stem cell-like properties in gastrointestinal cancer

International Journal of Oncology

Volumn 40, Issue 5, 2012, Pages 1423-1430

  Hoshino, Hiromitsu ^a   Nagano, Hiroaki ^a   Haraguchi, Naotsugu ^a   Nishikawa, Shimpei ^a   Tomokuni, Akira ^a   Kano, Yoshihiro ^a   Fukusumi, Takahito ^a   Saito, Toshiyuki ^b   Ozaki, Miyuki ^a   Sakai, Daisuke ^a   Satoh, Taroh ^a   Eguchi, Hidetoshi ^a   Sekimoto, Mitsugu ^a   Doki, Yuichiro ^a   Mori, Masaki ^a   Ishii, Hideshi ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Cancer reprogramming; Epigenome normalisation; Hypoxia; Tumour suppressor genes

Indexed keywords

KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P53; TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL HYPOXIA; CELL INVASION; CELL PROLIFERATION; CELL STRAIN HCT116; COLONY FORMATION; COLORECTAL CANCER; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; MOUSE; NONHUMAN; ONCOGENE C MYC; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RETROVIRUS INFECTION;

ANIMALS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HCT116 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LENTIVIRUS; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PROTO-ONCOGENE PROTEINS C-MYC; RETROVIRIDAE; RNA INTERFERENCE; SOXB1 TRANSCRIPTION FACTORS; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84860287098     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1346     Document Type: Article

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