Adverse perinatal events associated with ART

Seminars in Reproductive Medicine

Volumn 30, Issue 2, 2012, Pages 84-91

  Skora, Daniel ^a   Frankfurter, David ^a  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

assisted reproduction; cerebral palsy; congenital malformation; methylation disorder; multiple birth; perinatal morbidity and mortality

Indexed keywords

FERTILITY PROMOTING AGENT;

ANENCEPHALUS; ARTICLE; ASSISTED REPRODUCTIVE TECHNOLOGY; BECKWITH WIEDEMANN SYNDROME; BRAIN MALFORMATION; BREAST CANCER; CANCER RISK; CARDIOVASCULAR MALFORMATION; CHROMOSOME ABERRATION; CLEFT LIP; CLEFT PALATE; CONGENITAL MALFORMATION; CRYPTORCHISM; EDWARDS SYNDROME; EPISPADIAS; ESOPHAGUS ATRESIA; FALLOT TETRALOGY; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GASTROINTESTINAL MALFORMATION; GENETIC DISORDER; GENOME IMPRINTING; HAPPY PUPPET SYNDROME; HEART ATRIUM SEPTUM DEFECT; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HYDROCEPHALUS; HYDRONEPHROSIS; HYPOSPADIAS; INFERTILITY THERAPY; LOW BIRTH WEIGHT; MATERNAL AGE; MATERNAL HYPERTENSION; MOSAICISM; MULTIPLE PREGNANCY; NEUROBLASTOMA; OVARY CANCER; OVARY POLYCYSTIC DISEASE; PATENT DUCTUS ARTERIOSUS; PATIENT SAFETY; PERINATAL MORBIDITY; PERINATAL MORTALITY; PREMATURITY; PYLORUS STENOSIS; REPRODUCTION; SEX CHROMOSOME ABERRATION; SITUS INVERSUS; SPINA BIFIDA; SPINE MALFORMATION; SPONTANEOUS ABORTION; THYROID DISEASE; TRISOMY 21; UROGENITAL TRACT MALFORMATION; UTERUS MYOMA;

CEREBRAL PALSY; CONGENITAL ABNORMALITIES; FEMALE; GENOMIC IMPRINTING; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFERTILITY, FEMALE; MALE; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY, MULTIPLE; PREMATURE BIRTH; REPRODUCTIVE TECHNIQUES, ASSISTED;

EID: 84860283493     PISSN: 15268004     EISSN: 15264564     Source Type: Journal    
DOI: 10.1055/s-0032-1307416     Document Type: Article

References (78)

1. Finn H. "The Baby Chaseo". July 23, 2011. Wall Street Journal Online. URL: http://online.wsj.com/article/ SB10001424053111903461104576458134196248312.html
2. Centers for Disease Control and Prevention. MMWR surveillance summary: Assisted reproductive technologyUnited States. Available at: http://www.cdc.gov/media/pressrel/fs040430.htm. Accessed February 9, 2012
3. Pezeshki K, Feldman J, Stein DE, Lobel SM, Grazi RV. Bleeding and spontaneous abortion after therapy for infertility. Fertil Steril: 2000; 74 3 504 508
4. Wang JX, Norman RJ, Wilcox AJ. Incidence of spontaneous abortion among pregnancies produced by assisted reproductive technology. Hum Reprod: 2004; 19 2 272 277 (Pubitemid 38219992)
5. Schieve LA, Tatham L, Peterson HB, Toner J, Jeng G. Spontaneous abortion among pregnancies conceived using assisted reproductive technology in the United States. Obstet Gynecol: 2003; 101 5 Pt 1 959 967 (Pubitemid 36561262)
6. Templeton A, Morris JK. Reducing the risk of multiple births by transfer of two embryos after in vitro fertilization. N Engl J Med: 1998; 339 573 577 (Pubitemid 28385653)
7. Bhattacharya S, Templeton A. In treating infertility, are multiple pregnancies unavoidable? N Engl J Med: 2000; 343 58 59
8. Guzick DS, Carson SA, Coutifaris C., et al. Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network. N Engl J Med: 1999; 340 3 177 183 (Pubitemid 29063213)
9. Gardner DK, Schoolcraft WB, Wagley L., et al. A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization. Hum Repord: 1998; 13 12 3434 3440 (Pubitemid 29002638)
10. Frankfurter D, Trimarchi JF, Silva CP, Keefe DL. Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer. Fertil Steril: 2004; 81 5 1273 1277 (Pubitemid 38609310)
11. Gelbaya TA, Tsoumpou I, Nardo LG. The likelihood of live birth and multiple birth after single versus double embryo transfer at the cleavage stage: a systematic review and meta-analysis. Fertil Steril: 2010; 94 3 936 945
12. Bergh C. Single embryo transfer: a mini-review. Hum Reprod: 2005; 20 323 327 (Pubitemid 40277598)
13. Thurin A, Hausken J, Hillensjo T., et al. Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization. N Engl J Med: 2004; 351 2392 2402 (Pubitemid 40485991)
14. Centers for Disease Control and Prevention. Assisted reproductive technology (ART) report. Available at: http://apps.nccd.cdc.gov/art/Apps/ NationalSummaryReport.aspx. Accessed February 9, 2012
15. Pinborg A. IVF/ICSI twin pregnancies: risk and prevention. Hum Repord Update: 2005; 11 6 575 593 (Pubitemid 41631308)
16. Helmerhorst FM, Perquin DA, Donker D, Keirse MJ. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ: 2004; 328 7434 261
17. Derom C, Vlietinck R, Derom R, Van den Berghe H, Thiery M., et al. Increased monozygotic twinning rate after ovulation induction. Lancet: 1987; 1 1236 1238 (Pubitemid 17070809)
18. Derom C, Derom R, Vlietinck R, Maes H, Van den Berghe H. Iatrogenic multiple pregnancies in East Flanders, Belgium. Fertil Steril: 1993; 60 493 496 (Pubitemid 23278807)
19. Hershlag A, Paine T, Cooper GW, Scholl GM, Rawlinson K, Kvapil G. Monozygotic twinning associated with mechanical assisted hatching. Fertil Steril: 1999; 71 144 146 (Pubitemid 29042358)
20. Schieve LA, Meikle SF, Peterson HB, Jeng G, Burnett NM, Wilcox LS. Does assisted hatching pose a risk for monozygotic twinning in pregnancies conceived through in vitro fertilization? Fertil Steril: 2000; 74 2 288 294 (Pubitemid 30604192)
21. Frankfurter D, Trimarchi J, Hackett R, Meng L, Keefe D. Monozygotic pregnancies from transfers of zona-free blastocysts. Fertil Steril: 2004; 82 2 483 485 (Pubitemid 39092060)
22. Wright V, Schieve LA, Vahratian A, Reynolds MA. Monozygotic twinning associated with day 5 embryo transfer in pregnancies conceived after IVF. Hum Reprod: 2004; 19 8 1831 1836 (Pubitemid 39144632)
23. Rufat P, Olivennes F, de Mouzon J, Dehan M, Frydman R. Task force report on the outcome of pregnancies and children conceived by in vitro fertilization (France: 1987 to 1989). Fertil Steril: 2004; 61 2 324 330
24. Koudstaal J, Braat DD, Bruinse HW., et al. Obstetric outcome of singleton pregnancies after IVF: a matched control study in four Dutch university hospitals. Hum Reprod: 2000; 15 1819 1825 (Pubitemid 30636076)
25. Schieve LA, Ferre C, Peterson HB., et al. Perinatal outcome among singleton infants conceived through assisted reproductive technology in the United States. Obstet Gynecol: 2004; 103 6 1144 1153 (Pubitemid 40458943)
26. Schieve LA, Meikle SF, Ferre C, Peterson HB, Jeng G, Wilcox LS. Low and very low birth weight in infants conceived with use of assisted reproductive technology. N Engl J Med: 2002; 346 731 737 (Pubitemid 34983993)
27. Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet Gynecol: 2004; 103 551 556
28. Basso O, Weinberg CR, Baird DD, Wilcox AJ, Olsen J. Subfecundity as a correlate of preeclampsia: a study within the Danish National Birth Cohort. Am J Epidemiol: 2003; 157 195 202 (Pubitemid 36152432)
29. Manipalviratn S, DeCherney A, Segars J. Imprinting disorders and assisted reproductive technology. Fertil Steril: 2009; 91 2 305 315
30. Rivera RM, Stein P, Weaver JR., et al. Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development. Hum Mol Genet: 2008; 17 1 1 14
31. Marques CJ, Carvalho F, Sousa M, Barros A. Genomic imprinting in disruptive spermatogenesis. Lancet: 2004; 363 9422 1700 1702 (Pubitemid 38670329)
32. Fauque P, Jouannet P, Lesaffre C., et al. Assisted Reproductive Technology affects developmental kinetics, H19 Imprinting Control Region methylation and H19 gene expression in individual mouse embryos. BMC Dev Biol: 2007; 7 116
33. Kishino T, Lalande M, Wagstaff J. UBE3A/E6-AP mutations cause Angelman syndrome. Nat Genet: 1997; 15 1 70 73 (Pubitemid 27014952)
34. Junien C. Beckwith-Wiedemann syndrome, tumourigenesis and imprinting. Curr Opin Genet Dev: 1992; 2 431 438
35. Doornbos ME, Maas SM, McDonnell J, Vermeiden JP, Hennekam RC. Infertility, assisted reproduction technologies and imprinting disturbances: a Dutch study. Hum Reprod: 2007; 22 9 2476 2480 (Pubitemid 47289064)
36. Maher ER, Brueton LA, Bowdin SC., et al. Beckwith-Wiedemann syndrome and assisted reproduction technology (ART). J Med Genet: 2003; 40 1 62 64 (Pubitemid 36115128)
37. Gicquel C, Gaston V, Mandelbaum J, Siffroi JP, Flahault A, Le Bouc Y. In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN10T gene. Am J Hum Genet: 2003; 72 5 1338 1341 (Pubitemid 36530023)
38. Halliday J, Oke K, Breheny S, Algar E., J Amor D. Beckwith-Wiedemann syndrome and IVF: a case-control study. Am J Hum Genet: 2004; 75 3 526 528 (Pubitemid 39095829)
39. Lidegaard O, Pinborg A, Andersen AN. Imprinting diseases and IVF: Danish National IVF cohort study. Hum Reprod: 2005; 20 4 950 954 (Pubitemid 40674198)
40. Källn B, Finnstrom O, Nygren KG, Olausson PO. In vitro fertilization (IVF) in Sweden: risk for congenital malformations after different IVF methods. Birth Defects Res A Clin Mol Teratol: 2005; 73 3 162 169 (Pubitemid 40478241)
41. Cox GF, Burger JB, Lip V, Ulrike AM, Sperling K, Wu BL, Horsthemke B. Intracytoplasmic sperm injection may increase the risk of imprinting defects. Am J Hum Genet: 2002; 71 162 164 (Pubitemid 34734717)
42. Orstavik KH, Eiklid K, van der Hagen CV., et al. Another case of imprinting defect in a girl with Angelman syndrome who was conceived by intracytoplasmic semen injection. Am J Hum Genet: 2003; 72 1 218 219 (Pubitemid 36056860)
43. Ludwig M, Katalinic A, Gross S, Sutcliffe A, Varon R, Horsthemke B. Increased prevalence of imprinting defects in patients with Angelman syndrome born to subfertile couples. J Med Genet: 2005; 42 4 289 291 (Pubitemid 40523949)
44. Whittemore AS. The risk of ovarian cancer after treatment for infertility. N Engl J Med: 1994; 331 12 805 806 (Pubitemid 24284773)
45. Whittemore AS, Harris R, Itnyre J. Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer. Collaborative Ovarian Cancer Group. Am J Epidemiol: 1992; 136 10 1212 1220 (Pubitemid 23026892)
46. Rossing MA, Daling JF, Weiss NS, Moore DE, Self SG. Ovarian tumors in a cohort of infertile women. N Engl J Med: 1994; 331 12 771 776 (Pubitemid 24284766)
47. Venn A, Watson L, Lumley J, Giles G, King C, Healy D. Breast and ovarian cancer incidence after infertility and in vitro fertilization. Lancet: 1995; 346 8981 995 1000
48. Potashnik G, Lergner-Geva L, Genkin L, Chetrit A, Lunenfeld E, Porath A. Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study. Fertil Steril: 1999; 71 5 853 859 (Pubitemid 29206910)
49. Nygren KG, Finnstrom O, Källn B, Olausson PO. Population-based Swedish studies of outcomes after in vitro fertilization. Acta Obstet Gynecol Scand: 2007; 86 7 774 782 (Pubitemid 47035838)
50. Ness RB, Cramer DW, Goodman MT., et al. Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies. Am J Epidemiol: 2002; 155 3 217 224 (Pubitemid 34117299)
51. Kashyap S, Moher D, Fung MF, Rosenwaks Z. Assisted reproductive technology and the incidence of ovarian cancer: a meta-analysis. Obstet Gynecol: 2004; 103 4 785 794 (Pubitemid 40459044)
52. Kramer S, Ward E, Meadows AT, Malone KE. Medical and drug risk factors associated with neuroblastoma: a case-control study. J Natl Cancer Inst: 1987; 78 5 797 804 (Pubitemid 17093003)
53. Michalek AM, Buck GM, Nasca PC., et al. Gravid health status, medication use, and risk of neuroblastoma. Am J Epidemiol: 1996; 143 10 996 1001 (Pubitemid 26140326)
54. Lerner-Geva L, Toren A, Chetrit A., et al. The risk for cancer among children of women who underwent in vitro fertilization. Cancer: 2000; 88 12 2845 2847 (Pubitemid 30417948)
55. Bruinsma F, Venn A, Lancaster P, Speirs A, Healy D. Incidence of cancer in children born after in-vitro fertilization. Hum Repord: 2000; 15 3 604 607 (Pubitemid 30142369)
56. Källn B, Finnstrom O, Nygren KG, Olausson PO. In vitro fertilization in Sweden: child morbidity including cancer risk. Fertil Steril: 2005; 84 3 605 610 (Pubitemid 41317717)
57. Klip H, Burger CW, de Kraker J, van Leeuwen FE.; OMEGA-project group. Risk of cancer in the offspring of women who underwent ovarian stimulation for IVF. Hum Reprod: 2001; 16 11 2451 2458 (Pubitemid 33054154)
58. Draper ES, Kurinczuk JJ, Abrams KR, Clarke M. Assessment of separate contribution to perinatal motality of infertility history and treatment: a case-control analysis. Lancet: 1999; 353 9166 1746 1749 (Pubitemid 29240373)
59. De Sutter P, Veldeman L, Kok P., et al. Comparison of outcome of pregnancy after intra-uterine insemination (IUI) and IVF. Hum Reprod: 2005; 20 6 1642 1646 (Pubitemid 40852261)
60. Bonduelle M, Liebaers I, Deketekaere V., et al. Neonatal data on a cohort of 2889 infants born after ICSI (1991-1999) and of 2995 infants born after IVF (1983-1999). Human Reproduction: 2002; 17 3 671 694 (Pubitemid 34232438)
61. Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet Gynecol: 2004; 103 3 551 563 (Pubitemid 40459073)
62. Sutcliffe AG, Ludwig M. Outcome of assisted reproduction. Lancet: 2007; 370 9584 351 359 (Pubitemid 47094972)
63. Sutcliffe AG, Taylor B, Saunder K., et al. Outcome in the second year of life after in-vitro fertilization by intracytoplasmic sperm injection: a UK case-control study. Lancet: 2001; 357 9274 2080 2084 (Pubitemid 32607450)
64. Sutcliffe AG, Taylor B, Grudzinskas G, Thornton S, Liberman B. Children conceived by intracytoplasmic sperm injection. Lancet: 1998; 352 9127 578 579 (Pubitemid 28372245)
65. Reddy UM, Wapner RJ, Rebar RW, Tasca RJ. Infertility, assisted reproductive technology, and adverse pregnancy outcomes: executive summary of a National Institute of Child Health and Human Development workshop. Obstet Gynecol: 2007; 109 4 967 977 (Pubitemid 46559087)
66. Stromberg B, Dahlquist G, Ericson A, Finnstrom O, Koster M, Stjernqvist K. Neurological sequelae in children born after in-vitro fertilisation: a population-based study. Lancet: 2002; 359 9305 461 465 (Pubitemid 34164291)
67. Ericson A, Nygren KG, Olausson PO, Källn B. Hospital care utilization of infants born after IVF. Hum Reprod: 2002; 17 4 929 932 (Pubitemid 34411124)
68. Pharoah PO, Adi Y. Consequences of in-utero death in a twin pregnancy. Lancet: 2000; 355 1597 1602 (Pubitemid 30240504)
69. Pinborg A, Lidegaard O, la Cour Freiesleben N, Andersen AN. Consequences of vanishing twins in IVF/ICSI pregnancies. Hum Reprod: 2005; 20 2821 2829 (Pubitemid 41487639)
70. Barnes J, Sutcliffe AG, Kristoffersen I., et al. The influence of assisted reproduction on family functioning and children's socio-emotional development: results from a European study. Hum Reprod: 2004; 19 6 1480 1487 (Pubitemid 38807728)
71. Van Balen F. Child rearing following in vitro fertilization. J Child Psychol Psychiatry: 1996; 37 687 693 (Pubitemid 26302347)
72. Westergaard HB, Tranberg Johansen AM, Erb K, Nyboe Andersen A. Danish National IN-Bitro Fertilization Registry 1994 and 1995: a controlled study of births, malformations and cytogenetic findings. Hum Reprod: 1999; 14 7 1896 1902 (Pubitemid 29358723)
73. Ericson A, Källn B. Congenital malformations in infants born after IVF: a population-based study. Hum Reprod: 2001; 16 3 504 509 (Pubitemid 32218802)
74. Anthony S, Buitendijk SE, Dorrepaal CA., et al. Congenital malformations in 4224 children conceived after IVF. Hum Reprod: 2002; 17 8 2089 2095
75. Wennerholm UB, Bergh C, Hamberger L., et al. Incidence of congenital malformations in children born after ICSI. Hum Reprod: 2000; 15 4 944 948 (Pubitemid 30192750)
76. Lie RT, Lyngstadaas A, Orstavik KH, Bakketeig LS, Jacobsen G, Tanbo T. Birth defects in children conceived by ICSI compared with children conceived by other IVF-methods; a meta-analysis. Int J Epidemiol: 2005; 34 3 696 701 (Pubitemid 40852590)
77. Koivurova S, Hartikainen AL, Gissler M, Hemminki E, Sovio U, Jarvelin MR. Neonatal outcome an congenital malformations in children born after in-vitro fertilization. Hum Reprod: 2002; 17 5 1392 1398
78. Hansen M, Kurinczuk J, Bower C, Webb S. The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization. NEJM: 2002; 346 10 725 729