Predicting outcome in patients with acute liver failure: What works best?

Critical Care Medicine

Volumn 40, Issue 5, 2012, Pages 1666-1667

  Harbrecht, Brian G ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Acute liver failure; critical care; endothelium; liver; liver function; multiple organ dysfunction

Indexed keywords

ANGIOPOIETIN 2;

ACUTE LIVER FAILURE; CARBOHYDRATE METABOLISM; CYTOKINE PRODUCTION; DETOXIFICATION; DISEASE SEVERITY; EDITORIAL; ENERGY METABOLISM; HUMAN; LIVER DYSFUNCTION; LIVER FUNCTION TEST; LIVER TRANSPLANTATION; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PREDICTION; PRIORITY JOURNAL;

ANGIOPOIETIN-2; FEMALE; HUMANS; LIVER FAILURE, ACUTE; MALE;

EID: 84860261337     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182451f9f     Document Type: Editorial

References (17)

1. Knaus WA, Draper EA, Wagner DP, et al: APACHE II: A severity of disease classification system. Crit Care Med 1985; 13:818-829
2. Knaus WA, Wagner DP, Draper EA, et al: The APACHE III prognostic system: Risk prediction of hospital mortality for critically ill hospitalized patients. Chest 1991; 100:1619-1636
3. Marshall JC, Cook DJ, Christou NV, et al: Multiple Organ Dysfunction Score: A reliable description of a complex clinical outcome. Crit Care Med 1995; 23:1638-1652
4. Vincent JL, Moreno R, Takala J, et al: The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996; 22:707-710
5. Jungermann K, Kietzmann T: Oxygen: Modulator of metabolic zonation and disease of the liver. Hepatology 2000; 31:255-260
6. Ohno K, Maier P: Tumor necrosis factor a differentially modulates the cellular response of rat hepatocytes in periportal-and pericentral-equivalent cultures. Eur J Pharm 1995; 292:205-214
7. Jungermann K, Katz N: Functional specialization of different hepatocyte populations. Physiol Rev 1989; 69:708-764
8. Koo DJ, Chaudry IH, Wang P: Kupffer cells are responsible for producing inflammatory cytokines and hepatocellular dysfunction during early sepsis. J Surg Res 1999; 83:151-157
9. Salerno F, Borroni G, Moser P, et al: Prognostic value of the galactose test in predicting survival of patients with cirrhosis evaluated for liver transplantation: A prospective multicenter Italian study. J Hepatol 1996; 25: 474-480
10. Chandel B, Shapiro MJ, Kurtz M, et al: MEGX (monoethylglycinexylidide): a novel in vivo test to measure early hepatic dysfunction after hypovolemic shock. Shock 1995; 3:51-53
11. Harbrecht BG, Frye RF, Zenati MS, et al: Cytochrome P450 activity is differentially altered in severely injured patients. Crit Care Med 2005; 33:541-546
12. Ecochard M, Boillot O, Guillaud O, et al: Could metabolic liver function tests predict mortality on waiting list for liver transplant? A study on 560 patients. Clin Transplant 2011; 25:755-765
13. Zipprich A, Kuss O, Rogowski S, et al: Incorporating indocyanine green clearance into the Model for End Stage Liver Disease (MELD-ICG) improves prognostic accuracy in intermediate to advanced cirrhosis. Gut 2010; 59:963-968
14. Pelaez-Luna M, Martinez-Salgado J, Olivera-Martinez MA: Utility of the MAYO End-Stage Liver Disease score, King's College criteria, and a new in-hospital mortality score in the prognosis of in-hospital mortality in acute liver failure. Transplant Proceed 2006; 38:927-929
15. Bechmann LP, Jochum C, Kocabayoglu P, et al: Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury. J Hepatol 2010; 53:639-647
16. Hadem J, Bockmeyer CL, Lukasz A, et al: Angiopoietin-2 in acute liver failure. Crit Care Med 2012; 40:1499-1505
17. Schmidt LE, Larsen FS: Prognostic implications of hyperlactatemia, multiple organ failure, and systemic inflammatory response syndrome in patients with acetaminophen-induced acute liver failure. Crit Care Med 2006; 34:337-343