Engineering cellular trafficking via glycosyltransferase-programmed stereosubstitution

Annals of the New York Academy of Sciences

Volumn 1253, Issue 1, 2012, Pages 193-200

  Sackstein, Robert ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cell migration; GPS; HCELL; Hematopoietic stem cell; Mesenchymal stem cell

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCAN; GLYCOSYLTRANSFERASE; HERMES ANTIGEN; INTERLEUKIN 1; MESSENGER RNA; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VERY LATE ACTIVATION ANTIGEN 4;

CELL HOMING; CELL MIGRATION; CELL VIABILITY; GLYCOSYLATION; HEMATOPOIETIC STEM CELL; HUMAN; NONHUMAN; PHENOTYPE; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVIEW; THROMBOCYTE;

EID: 84860259545     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.06421.x     Document Type: Review

References (31)

1. Bernardo, M.E., F. Locatelli & W.E. Fibbe. 2009. Mesenchymal stromal cells. Ann. N. Y. Acad. Sci. 1176: 101-117.
2. Sackstein, R. 2009. Glycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migration. Immunol. Rev. 230: 51-74.
3. Lawrence, M.B. et al. 1997. Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L, P, E). J. Cell Biol. 136: 717-727.
4. Sackstein, R. 2005. The lymphocyte homing receptors: gatekeepers of the multistep paradigm. Curr. Opin. Hematol. 12: 444-450.
5. Li, Y. et al. 2006. ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding. Blood 108: 2275-2279.
6. Schweitzer, K.M. et al. 1996. Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues. Am. J. Pathol. 148: 165-175.
7. Weninger, W. et al. 2000. Specialized contributions by alpha(1, 3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Immunity 12: 665-676.
8. Yao, L. et al. 1999. Divergent inducible expression of P-selectin and E-selectin in mice and primates. Blood 94: 3820-3828.
9. Liu, Z. et al. 2010. Differential regulation of human and murine P-selectin expression and function in vivo. J. Exp. Med. 207: 2975-2987.
10. Ohmori, K. et al. 2000. P- and E-selectins recognize sialyl 6-sulfo Lewis X, the recently identified L-selectin ligand. Biochem. Biophys. Res. Commun. 278: 90-96.
11. Lawrence, M.B. & T.A. Springer. 1993. Neutrophils roll on E-selectin. J. Immunol. 151: 6338-6346.
12. Lawrence, M.B. et al. 1995. Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM-1 in shear flow. Eur. J. Immunol. 25: 1025-1031.
13. Jung, U. et al. 1996. Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo. Am. J. Physiol. 271: H2740-H2747.
14. Jung, U. & K. Ley. 1999. Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin. J. Immunol. 162: 6755-6762.
15. Merzaban, J.S. et al. 2011. Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells. Blood 118: 1774-1783.
16. Sackstein, R. & M. Borenstein. 1995. The effects of corticosteroids on lymphocyte recirculation in humans: analysis of the mechanism of impaired lymphocyte migration to lymph node following methylprednisolone administration. J. Investig. Med. 43: 68-77.
17. Sackstein, R. & C.J. Dimitroff. 2000. A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity. Blood 96: 2765-2774.
18. Dimitroff, C.J. et al. 2000. A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells. Proc. Natl. Acad. Sci. U. S. A. 97: 13841-13846.
19. Dimitroff, C.J. et al. 2001. CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J. Cell. Biol. 153: 1277-1286.
20. Sackstein, R. & R. Fuhlbrigge. 2009. Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assay. Methods Mol. Biol. 536: 343-354.
21. Patel, K.D., M.U. Nollert & R.P. McEver. 1995. P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils. J. Cell. Biol. 131: 1893-1902.
22. von Andrian, U.H. et al. 1995. A central role for microvillous receptor presentation in leukocyte adhesion under flow. Cell 82: 989-999.
23. Sipkins, D.A. et al. 2005. In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. Nature 435: 969-973.
24. Sackstein, R. 2004. The bone marrow is akin to skin: HCELL and the biology of hematopoietic stem cell homing. J. Invest. Dermatol. 122: 1061-1069.
25. Greenberg, A.W., W.G. Kerr & D.A. Hammer. 2000. Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development. Blood 95: 478-486.
26. Dagia, N.M. et al. 2006. G-CSF induces E-selectin ligand expression on human myeloid cells. Nat. Med. 12: 1185-1190.
27. Dimitroff, C.J. et al. 2001. Differential L-selectin binding activities of human hematopoietic cell L-selectin ligands, HCELL and PSGL-1. J. Biol. Chem. 276: 47623-47631.
28. Sackstein, R. 2011. The biology of CD44 and HCELL in hematopoiesis: the 'step 2-bypass pathway' and other emerging perspectives. Curr. Opin. Hematol. 18: 239-248.
29. Sackstein, R. 2010. Directing stem cell trafficking via GPS. Methods Enzymol. 479: 93-105.
30. Sackstein, R. et al. 2008. Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nat. Med. 14: 181-187.
31. Thankamony, S.P. & R. Sackstein. 2011. Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells. Proc. Natl. Acad. Sci. U. S. A. 108: 2258-2263.