-
1
-
-
0030794516
-
Long-Term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: A cooperative group study
-
Saxman SB, Propert KJ, Einhorn LH, et al. Long-Term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: A cooperative group study. J Clin Oncol 1997;15:2564-2569
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 2564-2569
-
-
Saxman, S.B.1
Propert, K.J.2
Einhorn, L.H.3
-
2
-
-
29144434734
-
Seven year update of an EORTC phase III trial of high-dose intensity M-VAC chemotherapy and G-CSF versus classic M-VAC in advanced urothelial tract tumours
-
Sternberg CN, De Mulder P, Schornagel JH, et al. Seven year update of an EORTC phase III trial of high-dose intensity M-VAC chemotherapy and G-CSF versus classic M-VAC in advanced urothelial tract tumours. Eur J Cancer 2006;42:50-54
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 50-54
-
-
Sternberg, C.N.1
De Mulder, P.2
Schornagel, J.H.3
-
3
-
-
23044501890
-
Long-Term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer
-
von der Maase H, Sengelov L, Roberts JT, et al. Long-Term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer. J Clin Oncol 2005;23:4602-4608
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 4602-4608
-
-
Von Der Maase, H.1
Sengelov, L.2
Roberts, J.T.3
-
4
-
-
36549023828
-
Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine (PCG) and gemcitabine/cisplatin (GC) in patients with locally advanced (LA) or metastatic (M) urothelial cancer without prior systemic therapy; EORTC30987/Intergroup study
-
(Meeting Abstracts)
-
Bellmunt J, von der Maase H, Mead GM, et al. Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine (PCG) and gemcitabine/cisplatin (GC) in patients with locally advanced (LA) or metastatic (M) urothelial cancer without prior systemic therapy; EORTC30987/Intergroup Study. J Clin Oncol (Meeting Abstracts) 2007;25:LBA5030
-
(2007)
J. Clin. Oncol.
, vol.25
-
-
Bellmunt, J.1
Von Der Maase, H.2
Mead, G.M.3
-
5
-
-
0041429507
-
Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer
-
Grossman HB, Natale RB, Tangen CM, et al. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003;349:859-866
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 859-866
-
-
Grossman, H.B.1
Natale, R.B.2
Tangen, C.M.3
-
6
-
-
79957960529
-
International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: Long-Term results of the BA06 30894 trial
-
Griffiths G, Hall R, Sylvester R, et al. International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: Long-Term results of the BA06 30894 trial. J Clin Oncol 2011;29:2171-2177
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2171-2177
-
-
Griffiths, G.1
Hall, R.2
Sylvester, R.3
-
7
-
-
21844450899
-
Medical research council clinical trials unit, neoadjuvant chemotherapy in invasive bladder cancer: Update of a systematic review and meta-Analysis of individual patient data advanced bladder cancer (ABC) meta-Analysis collaboration
-
Meta-Analysis Group discussion 205-6. 222 Euston Road, London NW1 2DA, UK
-
Vale CL, Meta-Analysis Group, Medical Research Council Clinical Trials Unit, Neoadjuvant chemotherapy in invasive bladder cancer: Update of a systematic review and meta-Analysis of individual patient data advanced bladder cancer (ABC) meta-Analysis collaboration. Eur Urol 2005;48:202-5; discussion 205-6. 222 Euston Road, London NW1 2DA, UK
-
(2005)
Eur. Urol.
, vol.48
, pp. 202-205
-
-
Vale, C.L.1
-
8
-
-
70149108534
-
Quality of pathologic response and surgery correlate with survival for patients with completely resected bladder cancer after neoadjuvant chemotherapy
-
Sonpavde G, Goldman BH, Speights VO, et al. Quality of pathologic response and surgery correlate with survival for patients with completely resected bladder cancer after neoadjuvant chemotherapy. Cancer 2009;115:4104-4109
-
(2009)
Cancer
, vol.115
, pp. 4104-4109
-
-
Sonpavde, G.1
Goldman, B.H.2
Speights, V.O.3
-
9
-
-
79952012493
-
A consensus definition of patients with metastatic urothelial carcinoma who are unfit for cisplatin-based chemotherapy
-
Galsky MD, Hahn NM, Rosenberg J, et al. A consensus definition of patients with metastatic urothelial carcinoma who are unfit for cisplatin-based chemotherapy. Lancet Oncol 2011;12:211-214
-
(2011)
Lancet Oncol.
, vol.12
, pp. 211-214
-
-
Galsky, M.D.1
Hahn, N.M.2
Rosenberg, J.3
-
10
-
-
79959191493
-
Treatment of patients with metastatic urothelial cancer unfit for Cisplatin-based chemotherapy
-
Galsky MD, Hahn NM, Rosenberg J, et al. Treatment of patients with metastatic urothelial cancer "unfit" for Cisplatin-based chemotherapy. J Clin Oncol 2011;29:2432-2438
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2432-2438
-
-
Galsky, M.D.1
Hahn, N.M.2
Rosenberg, J.3
-
11
-
-
84863011634
-
Comparative effectiveness of cisplatin-based and carboplatin-based chemotherapy for treatment of advanced urothelial carcinoma
-
Galsky MD, Chen GJ, Oh WK, et al. Comparative effectiveness of cisplatin-based and carboplatin-based chemotherapy for treatment of advanced urothelial carcinoma. Ann Oncol 2012;23(2):406-410
-
(2012)
Ann. Oncol.
, vol.23
, Issue.2
, pp. 406-410
-
-
Galsky, M.D.1
Chen, G.J.2
Oh, W.K.3
-
12
-
-
84855583390
-
Randomized Phase II/III Trial assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC Study 30986
-
De Santis M, Bellmunt J, Mead G, et al. Randomized Phase II/III Trial assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC Study 30986. J Clin Oncol 2009;30:191-199
-
(2009)
J. Clin. Oncol.
, vol.30
, pp. 191-199
-
-
De Santis, M.1
Bellmunt, J.2
Mead, G.3
-
13
-
-
75149128685
-
Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract
-
Bellmunt J, Theodore C, Demkov T, et al. Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract. J Clin Oncol 2009;27:4454-4461
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4454-4461
-
-
Bellmunt, J.1
Theodore, C.2
Demkov, T.3
-
14
-
-
0032887956
-
Long-Term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy
-
Bajorin DF, Dodd PM, Mazumdar M, et al. Long-Term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy. J Clin Oncol 1999;17:3173-3181
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3173-3181
-
-
Bajorin, D.F.1
Dodd, P.M.2
Mazumdar, M.3
-
15
-
-
77951626194
-
Prognostic factors in patients with advanced transitional cell carcinoma of the urothelial tract experiencing treatment failure with platinum-containing regimens
-
Bellmunt J, Choueiri TK, Fougeray R, et al. Prognostic factors in patients with advanced transitional cell carcinoma of the urothelial tract experiencing treatment failure with platinum-containing regimens. J Clin Oncol 2009;28:1850-1855
-
(2009)
J. Clin. Oncol.
, vol.28
, pp. 1850-1855
-
-
Bellmunt, J.1
Choueiri, T.K.2
Fougeray, R.3
-
17
-
-
0033949997
-
The natural history of bladder cancer. Implications for therapy
-
vii
-
Lee R, Droller MJ. The natural history of bladder cancer. Implications for therapy. Urol Clin North Am 2000;27:1-13; vii.
-
(2000)
Urol Clin North Am
, vol.27
, pp. 1-13
-
-
Lee, R.1
Droller, M.J.2
-
18
-
-
0028036255
-
Two molecular pathways to transitional cell carcinoma of the bladder
-
Spruck CH III, Ohneseit PF, Gonzalez-Zulueta M, et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 1994;54:784-788
-
(1994)
Cancer Res.
, vol.54
, pp. 784-788
-
-
Spruck III, C.H.1
Ohneseit, P.F.2
Gonzalez-Zulueta, M.3
-
19
-
-
10744222289
-
FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder
-
Bakkar AA, Wallerand H, Radvanyi F, et al. FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder. Cancer Res 2003;63:8108-8112
-
(2003)
Cancer Res.
, vol.63
, pp. 8108-8112
-
-
Bakkar, A.A.1
Wallerand, H.2
Radvanyi, F.3
-
20
-
-
34548407864
-
FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
-
Tomlinson DC, Baldo O, Harnden P, et al. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J Pathol 2007;213:91-98
-
(2007)
J. Pathol.
, vol.213
, pp. 91-98
-
-
Tomlinson, D.C.1
Baldo, O.2
Harnden, P.3
-
22
-
-
27544438631
-
Chromosomal changes in uroepithelial carcinomas
-
Fadl-Elmula I. Chromosomal changes in uroepithelial carcinomas. Cell Chromosome 2005;4:1
-
(2005)
Cell Chromosome
, vol.4
, pp. 1
-
-
Fadl-Elmula, I.1
-
23
-
-
33644868287
-
Molecular subtypes of bladder cancer: Jekyll and hyde or chalk and cheese
-
Knowles MA. Molecular subtypes of bladder cancer: jekyll and Hyde or chalk and cheese? Carcinogenesis 2006;27:361-373
-
(2006)
Carcinogenesis
, vol.27
, pp. 361-373
-
-
Knowles, M.A.1
-
24
-
-
55249109226
-
Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: A long-Term study
-
Salinas-Sanchez AS, Lorenzo-Romero JG, Gimenez-Bachs JM, et al. Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: A long-Term study. Urol Oncol 2008;26:620-626
-
(2008)
Urol. Oncol.
, vol.26
, pp. 620-626
-
-
Salinas-Sanchez, A.S.1
Lorenzo-Romero, J.G.2
Gimenez-Bachs, J.M.3
-
25
-
-
68149179652
-
P53 predictive value for pT1-2 N0 disease at radical cystectomy
-
Shariat SF, Lotan Y, Karakiewicz PI, et al. p53 predictive value for pT1-2 N0 disease at radical cystectomy. J Urol 2009;182:907-913
-
(2009)
J. Urol.
, vol.182
, pp. 907-913
-
-
Shariat, S.F.1
Lotan, Y.2
Karakiewicz, P.I.3
-
26
-
-
0029985494
-
Loss of heterozygosity at the p53, RB, DCC and APC tumor suppressor gene loci in human bladder cancer
-
Miyamoto H, Shuin T, Ikeda I, et al. Loss of heterozygosity at the p53, RB, DCC and APC tumor suppressor gene loci in human bladder cancer. J Urol 1996;155:1444-1447
-
(1996)
J. Urol.
, vol.155
, pp. 1444-1447
-
-
Miyamoto, H.1
Shuin, T.2
Ikeda, I.3
-
27
-
-
0033965916
-
Bladder cancer: Allelic deletions at and around the retinoblastoma tumor suppressor gene in relation to stage and grade
-
Wada T, Louhelainen J, Hemminki K, et al. Bladder cancer: Allelic deletions at and around the retinoblastoma tumor suppressor gene in relation to stage and grade. Clin Cancer Res 2000;6:610-615
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 610-615
-
-
Wada, T.1
Louhelainen, J.2
Hemminki, K.3
-
28
-
-
69849115183
-
Generation of a concise gene panel for outcome prediction in urinary bladder cancer
-
Mitra AP, Pagliarulo V, Yang D, et al. Generation of a concise gene panel for outcome prediction in urinary bladder cancer. J Clin Oncol 2009;27:3929-3937
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3929-3937
-
-
Mitra, A.P.1
Pagliarulo, V.2
Yang, D.3
-
29
-
-
33846469888
-
Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
-
Karam JA, Lotan Y, Karakiewicz PI, et al. Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy. Lancet Oncol 2007;8:128-136
-
(2007)
Lancet Oncol.
, vol.8
, pp. 128-136
-
-
Karam, J.A.1
Lotan, Y.2
Karakiewicz, P.I.3
-
30
-
-
1842457693
-
P53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer
-
Shariat SF, Tokunaga H, Zhou J, et al. p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer. J Clin Oncol 2004;22:1014-1024
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1014-1024
-
-
Shariat, S.F.1
Tokunaga, H.2
Zhou, J.3
-
31
-
-
69549114870
-
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
-
Chan KS, Espinosa I, Chao M, et al. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc. Natl. Acad. Sci. USA 2009;106:14016-21
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14016-21
-
-
Chan, K.S.1
Espinosa, I.2
Chao, M.3
-
32
-
-
68049148065
-
Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma
-
He X, Marchionni L, Hansel DE, et al. Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma. Stem Cells 2009;27:1487-1495
-
(2009)
Stem. Cells
, vol.27
, pp. 1487-1495
-
-
He, X.1
Marchionni, L.2
Hansel, D.E.3
-
33
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
34
-
-
0032521539
-
Molecular mediators of angiogenesis in bladder cancer
-
Campbell SC, Volpert OV, Ivanovich M, et al. Molecular mediators of angiogenesis in bladder cancer. Cancer Res 1998;58:1298-1304
-
(1998)
Cancer Res.
, vol.58
, pp. 1298-1304
-
-
Campbell, S.C.1
Volpert, O.V.2
Ivanovich, M.3
-
35
-
-
1642578897
-
The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion
-
Wu X, Obata T, Khan Q, et al. The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion. BJU Int 2004;93:143-150
-
(2004)
BJU Int.
, vol.93
, pp. 143-150
-
-
Wu, X.1
Obata, T.2
Khan, Q.3
-
36
-
-
14644429809
-
Expression of angiopoietin-1 and -2, and its clinical significance in human bladder cancer
-
Oka N, Yamamoto Y, Takahashi M, et al. Expression of angiopoietin-1 and -2, and its clinical significance in human bladder cancer. BJU Int 2005;95:660-663
-
(2005)
BJU Int.
, vol.95
, pp. 660-663
-
-
Oka, N.1
Yamamoto, Y.2
Takahashi, M.3
-
37
-
-
66349120144
-
Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-Activated protein kinase pathway in bladder cancer
-
Tomlinson DC, Lamont FR, Shnyder SD, et al. Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-Activated protein kinase pathway in bladder cancer. Cancer Res 2009;69:4613-4620
-
(2009)
Cancer Res.
, vol.69
, pp. 4613-4620
-
-
Tomlinson, D.C.1
Lamont, F.R.2
Shnyder, S.D.3
-
38
-
-
33644867290
-
Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
-
Sanchez-Carbayo M, Socci ND, Lozano J, et al. Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J Clin Oncol 2006;24:778-789
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 778-789
-
-
Sanchez-Carbayo, M.1
Socci, N.D.2
Lozano, J.3
-
40
-
-
36148957497
-
Loss of P16 expression and chromosome 9p21 LOH in predicting outcome of patients affected by superficial bladder cancer
-
Bartoletti R, Cai T, Nesi G, et al. Loss of P16 expression and chromosome 9p21 LOH in predicting outcome of patients affected by superficial bladder cancer. J Surg Res 2007;143:422-427
-
(2007)
J. Surg. Res.
, vol.143
, pp. 422-427
-
-
Bartoletti, R.1
Cai, T.2
Nesi, G.3
-
41
-
-
33847290778
-
Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk
-
Garcia-Closas M, Malats N, Real FX, et al. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet 2007;3:e29
-
(2007)
Plos. Genet.
, vol.3
-
-
Garcia-Closas, M.1
Malats, N.2
Real, F.X.3
-
42
-
-
77953847133
-
Molecular genetics of bladder cancer: Emerging mechanisms of tumor initiation and progression
-
McConkey DJ, Lee S, Choi W, et al. Molecular genetics of bladder cancer: Emerging mechanisms of tumor initiation and progression. Urol Oncol 2010;28:429-440
-
(2010)
Urol. Oncol.
, vol.28
, pp. 429-440
-
-
McConkey, D.J.1
Lee, S.2
Choi, W.3
-
43
-
-
27144524894
-
RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors
-
Kim WJ, Kim EJ, Jeong P, et al. RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. Cancer Res 2005;65:9347-9354
-
(2005)
Cancer Res.
, vol.65
, pp. 9347-9354
-
-
Kim, W.J.1
Kim, E.J.2
Jeong, P.3
-
44
-
-
0035893756
-
Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features
-
Maruyama R, Toyooka S, Toyooka KO, et al. Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features. Cancer Res 2001;61:8659-8663
-
(2001)
Cancer Res.
, vol.61
, pp. 8659-8663
-
-
Maruyama, R.1
Toyooka, S.2
Toyooka, K.O.3
-
45
-
-
0033896830
-
Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer
-
Muto S, Horie S, Takahashi S, et al. Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer. Cancer Res 2000;60:4021-4025
-
(2000)
Cancer Res.
, vol.60
, pp. 4021-4025
-
-
Muto, S.1
Horie, S.2
Takahashi, S.3
-
46
-
-
0027167033
-
Expression of basic fibroblast growth factor and its receptor in an invasive bladder carcinoma cell line
-
Allen LE, Maher PA. Expression of basic fibroblast growth factor and its receptor in an invasive bladder carcinoma cell line. J Cell Physiol 1993;155:368-375
-
(1993)
J. Cell Physiol.
, vol.155
, pp. 368-375
-
-
Allen, L.E.1
Maher, P.A.2
-
47
-
-
0030678133
-
Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer
-
Crew JP, O'Brien T, Bradburn M, et al. Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer. Cancer Res 1997;57:5281-5285
-
(1997)
Cancer Res.
, vol.57
, pp. 5281-5285
-
-
Crew, J.P.1
O'Brien, T.2
Bradburn, M.3
-
48
-
-
68549125346
-
Effect of vascular endothelial growth factor and its receptor inhibitor on proliferation and invasion in bladder cancer
-
Nakanishi R, Oka N, Nakatsuji H, et al. Effect of vascular endothelial growth factor and its receptor inhibitor on proliferation and invasion in bladder cancer. Urol Int 2009;83:98-106
-
(2009)
Urol. Int.
, vol.83
, pp. 98-106
-
-
Nakanishi, R.1
Oka, N.2
Nakatsuji, H.3
-
49
-
-
0027502358
-
Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients
-
Nguyen M, Watanabe H, Budson AE, et al. Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients. J Natl Cancer Inst 1993;85:241-242
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 241-242
-
-
Nguyen, M.1
Watanabe, H.2
Budson, A.E.3
-
50
-
-
0028961523
-
Different angiogenic pathways characterize superficial and invasive bladder cancer
-
O'Brien T, Cranston D, Fuggle S, et al. Different angiogenic pathways characterize superficial and invasive bladder cancer. Cancer Res 1995;55:510-513
-
(1995)
Cancer Res.
, vol.55
, pp. 510-513
-
-
O'Brien, T.1
Cranston, D.2
Fuggle, S.3
-
51
-
-
0346499095
-
Correlation of metastasis related gene expression and relapse-free survival in patients with locally advanced bladder cancer treated with cystectomy and chemotherapy
-
Slaton JW, Millikan R, Inoue K, et al. Correlation of metastasis related gene expression and relapse-free survival in patients with locally advanced bladder cancer treated with cystectomy and chemotherapy. J Urol 2004;171:570-574
-
(2004)
J. Urol.
, vol.171
, pp. 570-574
-
-
Slaton, J.W.1
Millikan, R.2
Inoue, K.3
-
52
-
-
6444226075
-
Alteration of the vascular endothelial growth factor and angiopoietins-1 and -2 pathways in transitional cell carcinomas of the urinary bladder associated with tumor progression
-
Quentin T, Schlott T, Korabiowska M, et al. Alteration of the vascular endothelial growth factor and angiopoietins-1 and -2 pathways in transitional cell carcinomas of the urinary bladder associated with tumor progression. Anticancer Res 2004;24:2745-2756
-
(2004)
Anticancer Res.
, vol.24
, pp. 2745-2756
-
-
Quentin, T.1
Schlott, T.2
Korabiowska, M.3
-
53
-
-
48849100188
-
Microvessel density (MVD) and cyclooxygenase-2 (COX-2)/beta-catenin interaction are associated with relapse in patients with transitional carcinoma receiving adjuvant chemotherapy with paclitaxel/carboplatin: A hellenic cooperative oncology group (HECOG) study
-
Bamias A, Kyriakou F, Chorti M, et al. Microvessel density (MVD) and cyclooxygenase-2 (COX-2)/beta-catenin interaction are associated with relapse in patients with transitional carcinoma receiving adjuvant chemotherapy with paclitaxel/carboplatin: A hellenic cooperative oncology group (HECOG) study. Anticancer Res 2008;28:2479-2486
-
(2008)
Anticancer Res.
, vol.28
, pp. 2479-2486
-
-
Bamias, A.1
Kyriakou, F.2
Chorti, M.3
-
54
-
-
79955006416
-
Phase II trial of cisplatin, gemcitabine, and bevacizumab as first-line therapy for metastatic urothelial carcinoma: Hoosier Oncology Group GU 04-75
-
Hahn NM, Stadler WM, Zon RT, et al. Phase II trial of cisplatin, gemcitabine, and bevacizumab as first-line therapy for metastatic urothelial carcinoma: Hoosier Oncology Group GU 04-75. J Clin Oncol 2011;29:1525-1530
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1525-1530
-
-
Hahn, N.M.1
Stadler, W.M.2
Zon, R.T.3
-
55
-
-
84857209343
-
Phase II trial of gemcitabine, carboplatin, and bevacizumab in chemotherapy-naive patients (Pts) with advanced/metastatic urothelial carcinoma
-
abstract
-
Balar AV, Milowsky MI, Apolo AB, et al. Phase II trial of gemcitabine, carboplatin, and bevacizumab in chemotherapy-naive patients (Pts) with advanced/metastatic urothelial carcinoma. J Clin Oncol 2011;29(suppl 7):abstract 248
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.7
, pp. 248
-
-
Balar, A.V.1
Milowsky, M.I.2
Apolo, A.B.3
-
56
-
-
84906801956
-
Memorial sloan-kettering cancer center New York NY: Vascular thromboembolic events in patients (pts) with advanced urothelial cancer (UC) treated with carboplatin/gemcitabine alone or in combination with bevacizumab
-
Apolo AB, Regazzi AM, Milowsky MI, Bajorin DF. Memorial Sloan-Kettering Cancer Center, New York, NY: Vascular thromboembolic events in patients (pts) with advanced urothelial cancer (UC) treated with carboplatin/gemcitabine alone or in combination with bevacizumab. Presented at the 2009 ASCO Annual Meeting; 2009
-
(2009)
Presented at the 2009 ASCO Annual Meeting
-
-
Apolo, A.B.1
Regazzi, A.M.2
Milowsky, M.I.3
Bajorin, D.F.4
-
57
-
-
84906805449
-
Phase II trial of neoadjuvant cisplatin gemcitabine and bevacizumab followed by radical cystectomy (RC) in patients with muscle-invasive transitional cell carcinoma (TCC) of the bladder [abstract 276]
-
Chaudhary UB, Golshayan AR, Brisendine A, et al. Phase II trial of neoadjuvant cisplatin, gemcitabine and bevacizumab followed by radical cystectomy (RC) in patients with muscle-invasive transitional cell carcinoma (TCC) of the bladder [abstract 276]. Genitourinar cancer symposium; 2011
-
(2011)
Genitourinar Cancer Symposium
-
-
Chaudhary, U.B.1
Golshayan, A.R.2
Brisendine, A.3
-
58
-
-
84860242276
-
Neoadjuvant chemotherapy with DD-MVAC and bevacizumab in high-risk urothelial cancer: Results from a phase II trial at the MD anderson cancer center
-
abstract
-
Siefker-Radtke AO, Kamat A, Corn PG, et al. Neoadjuvant chemotherapy with DD-MVAC and bevacizumab in high-risk urothelial cancer: Results from a phase II trial at the M. D. Anderson Cancer Center. J Clin Oncol 2012;30(Suppl 5):abstract 261
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.SUPPL. 5
, pp. 261
-
-
Siefker-Radtke, A.O.1
Kamat, A.2
Corn, P.G.3
-
59
-
-
77957756488
-
Phase II study of Aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a california cancer consortium trial
-
Twardowski P, Stadler WM, Frankel P, et al. Phase II study of Aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial. Urology 2010;76:923-926
-
(2010)
Urology
, vol.76
, pp. 923-926
-
-
Twardowski, P.1
Stadler, W.M.2
Frankel, P.3
-
60
-
-
67649354223
-
Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model
-
Sonpavde G, Jian W, Liu H, et al. Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model. Urol Oncol 2009;27:391-399
-
(2009)
Urol. Oncol.
, vol.27
, pp. 391-399
-
-
Sonpavde, G.1
Jian, W.2
Liu, H.3
-
61
-
-
80053270703
-
Phase II study of sunitinib as first-line treatment of urothelial cancer patients ineligible to receive cisplatin-based chemotherapy: Baseline interleukin-8 and tumor contrast enhancement as potential predictive factors of activity
-
Bellmunt J, Gonzalez-Larriba JL, Prior C, et al. Phase II study of sunitinib as first-line treatment of urothelial cancer patients ineligible to receive cisplatin-based chemotherapy: Baseline interleukin-8 and tumor contrast enhancement as potential predictive factors of activity. Ann Oncol 2011;22:2646-2653
-
(2011)
Ann. Oncol.
, vol.22
, pp. 2646-2653
-
-
Bellmunt, J.1
Gonzalez-Larriba, J.L.2
Prior, C.3
-
62
-
-
77950474660
-
Phase II study of sunitinib in patients with metastatic urothelial cancer
-
Gallagher DJ, Milowsky MI, Gerst SR, et al. Phase II study of sunitinib in patients with metastatic urothelial cancer. J Clin Oncol 2010;28:1373-1379
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1373-1379
-
-
Gallagher, D.J.1
Milowsky, M.I.2
Gerst, S.R.3
-
63
-
-
84860232170
-
Randomized phase II trial of maintenance sunitinib versus placebo following response to chemotherapy (CT) for patients (pts) with advanced urothelial carcinoma (UC)
-
abstract
-
Grivas P, Nanus DM, Stadler WM, et al. Randomized phase II trial of maintenance sunitinib versus placebo following response to chemotherapy (CT) for patients (pts) with advanced urothelial carcinoma (UC). J Clin Oncol 2012;30(Suppl 5):abstract 265
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.5
, pp. 265
-
-
Grivas, P.1
Nanus, D.M.2
Stadler, W.M.3
-
64
-
-
77958460273
-
Phase II study of gemcitabine, cisplatin, and sunitinib in patients with advanced urothelial carcinoma
-
(suppl; abstr 4573)
-
Galsky MD, Sonpavde G, Hellerstedt BA, et al. Phase II study of gemcitabine, cisplatin, and sunitinib in patients with advanced urothelial carcinoma. J Clin Oncol 2010;28:15s (suppl; abstr 4573)
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Galsky, M.D.1
Sonpavde, G.2
Hellerstedt, B.A.3
-
65
-
-
70149124507
-
Phase 2 trial of sorafenib in patients with advanced urothelial cancer: A trial of the Eastern Cooperative Oncology Group
-
Dreicer R, Li H, Stein M, et al. Phase 2 trial of sorafenib in patients with advanced urothelial cancer: A trial of the Eastern Cooperative Oncology Group. Cancer 2009;115:4090-4095
-
(2009)
Cancer
, vol.115
, pp. 4090-4095
-
-
Dreicer, R.1
Li, H.2
Stein, M.3
-
66
-
-
84856071311
-
A phase II trial of sorafenib in first-line metastatic urothelial cancer: A study of the PMH Phase II Consortium
-
Sridhar SS, Winquist E, Eisen A, et al. A phase II trial of sorafenib in first-line metastatic urothelial cancer: A study of the PMH Phase II Consortium. Investigational new drugs 2011;29:1045-1049
-
(2011)
Investigational new drugs
, vol.29
, pp. 1045-1049
-
-
Sridhar, S.S.1
Winquist, E.2
Eisen, A.3
-
67
-
-
84906796873
-
-
Roswell Park Cancer Institute, Buffalo, NY;Mayo Clinic Rochester, Rochester, MN; Metro Minnesota, Minneapolis, MN; Washington University School of Medicine, St Louis, MO; Sir Charles Gairdner Hospital, Nedlands, Australia; Prince of Wales Hospital, Shatin, Hong Kong; Mayo Clinic Jacksonville, Jacksonville, FL; Karmanos Cancer Institute, Wayne State University, Detroit, MI: MC0553: A phase II safety and efficacy study with the VEGF receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer.
-
Pili R, Qin R, Flynn PJ, et al. Roswell Park Cancer Institute, Buffalo, NY;Mayo Clinic Rochester, Rochester, MN; Metro Minnesota, Minneapolis, MN; Washington University School of Medicine, St. Louis, MO; Sir Charles Gairdner Hospital, Nedlands, Australia; Prince of Wales Hospital, Shatin, Hong Kong; Mayo Clinic Jacksonville, Jacksonville, FL; Karmanos Cancer Institute, Wayne State University, Detroit, MI: MC0553: A phase II safety and efficacy study with the VEGF receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer. Presented at the 2011 Genitourinary cancers symposium; 2011
-
(2011)
Presented at the 2011 Genitourinary Cancers Symposium
-
-
Pili, R.1
Qin, R.2
Flynn, P.J.3
-
68
-
-
83455209334
-
-
Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy; Institute for Cancer Research and Treatment Turin Italy; Azienda Ospedaliera Universitaria Integrata Verona Verona Italy; Ospedali Riuniti di Bergamo Bergamo Italy;University Hospital of Udine Udine Italy: Updated results of INT70/09 phase II study of pazopanib (PZP) monotherapy for patients with relapsed/refractory urothelial cancer (UC) (Suppl):abstract
-
Necchi A, Nicolai N, Ortega C, et al. Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Institute for Cancer Research and Treatment, Turin, Italy; Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy; Ospedali Riuniti di Bergamo, Bergamo, Italy;University Hospital of Udine, Udine, Italy: Updated results of INT70/09 phase II study of pazopanib (PZP) monotherapy for patients with relapsed/refractory urothelial cancer (UC). J Clin Oncol 2011;29(Suppl):abstract 4618
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4618
-
-
Necchi, A.1
Nicolai, N.2
Ortega, C.3
-
69
-
-
84856851592
-
Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer
-
Choueiri TK, Ross RW, Jacobus S, et al. Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer. J Clin Oncol 2012;30(5):507-512
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.5
, pp. 507-512
-
-
Choueiri, T.K.1
Ross, R.W.2
Jacobus, S.3
-
70
-
-
0028883362
-
Prognostic value of amplification of c-erb-B2 in bladder carcinoma
-
Lonn U, Lonn S, Friberg S, et al. Prognostic value of amplification of c-erb-B2 in bladder carcinoma. Clin Cancer Res 1995;1:1189-1194
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1189-1194
-
-
Lonn, U.1
Lonn, S.2
Friberg, S.3
-
71
-
-
0032989236
-
Epidermal growth factor receptor expression: Predictive value for the outcome after cystectomy for bladder cancer
-
Sriplakich S, Jahnson S, Karlsson MG. Epidermal growth factor receptor expression: Predictive value for the outcome after cystectomy for bladder cancer? BJU Int 1999;83:498-503
-
(1999)
BJU Int.
, vol.83
, pp. 498-503
-
-
Sriplakich, S.1
Jahnson, S.2
Karlsson, M.G.3
-
72
-
-
18544389657
-
Analysis of HER2 expression in primary urinary bladder carcinoma and corresponding metastases
-
Gardmark T, Wester K, De la Torre M, et al. Analysis of HER2 expression in primary urinary bladder carcinoma and corresponding metastases. BJU Int 2005;95:982-986
-
(2005)
BJU Int.
, vol.95
, pp. 982-986
-
-
Gardmark, T.1
Wester, K.2
De La Torre, M.3
-
73
-
-
69349087756
-
MIR-200 expression regulates epithelial-To-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy
-
Adam L, Zhong M, Choi W, et al. miR-200 expression regulates epithelial-To-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res 2009;15:5060-5072
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5060-5072
-
-
Adam, L.1
Zhong, M.2
Choi, W.3
-
74
-
-
84906799355
-
-
Fox Chase Cancer Center, Philadelphia, PA; University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Pottstown Cancer Center, Pottstown, PA; Hematology Oncology Associates, Mt. Holly, NJ; Paoli Cancer Center, Paoli, PA; Fox Chase Extramural Research Network, Philadelphia, PA: Effect of EGFR inhibition with cetuximab (CET) on the efficacy of paclitaxel (TAX) in previously treated metastatic (MET) urothelial cancer. Presented at the ASCO 2011 (Suppl):abstract
-
Wong Y, Litwin S, Vaughn DJ, et al. Fox Chase Cancer Center, Philadelphia, PA; University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Pottstown Cancer Center, Pottstown, PA; Hematology Oncology Associates, Mt. Holly, NJ; Paoli Cancer Center, Paoli, PA; Fox Chase Extramural Research Network, Philadelphia, PA: Effect of EGFR inhibition with cetuximab (CET) on the efficacy of paclitaxel (TAX) in previously treated metastatic (MET) urothelial cancer. Presented at the ASCO 2011. J Clin Oncol 2011;29(Suppl):abstract 4617
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4617
-
-
Wong, Y.1
Litwin, S.2
Vaughn, D.J.3
-
75
-
-
3242702175
-
Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer
-
Dominguez-Escrig JL, Kelly JD, Neal DE, et al. Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer. Clin Cancer Res 2004;10:4874-4884
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4874-4884
-
-
Dominguez-Escrig, J.L.1
Kelly, J.D.2
Neal, D.E.3
-
76
-
-
83455179375
-
Investigation of the EGFR gene variations in bladder cancer patients using INFINITITM Analyzer
-
Tiryakioglu Ok NO, Cakir OO, Tunali NE. Investigation of the EGFR gene variations in bladder cancer patients using INFINITITM Analyzer. J Cell Mol Biol 2011;9:83-86
-
(2011)
J. Cell Mol. Biol.
, vol.9
, pp. 83-86
-
-
Tiryakioglu Ok, N.O.1
Cakir, O.O.2
Tunali, N.E.3
-
78
-
-
75149171017
-
Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium
-
Petrylak DP, Tangen CM, Van Veldhuizen PJ Jr, et al. Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium. BJU Int 2010;105(3):317-321
-
(2010)
BJU Int.
, vol.105
, Issue.3
, pp. 317-321
-
-
Petrylak, D.P.1
Tangen, C.M.2
Van Veldhuizen Jr., P.J.3
-
79
-
-
77953434938
-
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results
-
Pruthi RS, Nielsen M, Heathcote S, et al. A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results. BJU Int 2010;106:349-356
-
(2010)
BJU Int.
, vol.106
, pp. 349-356
-
-
Pruthi, R.S.1
Nielsen, M.2
Heathcote, S.3
-
80
-
-
77953434938
-
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results
-
Pruthi RS, Nielsen M, Heathcote S, et al. A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results. BJU Int 2010;106:349-354
-
(2010)
BJU Int.
, vol.106
, pp. 349-354
-
-
Pruthi, R.S.1
Nielsen, M.2
Heathcote, S.3
-
81
-
-
66149084012
-
A phase II trial of cisplatin (C), gemcitabine (G) and gefitinib for advanced urothelial tract carcinoma: Results of Cancer and Leukemia Group B (CALGB) 90102
-
Philips GK, Halabi S, Sanford BL, et al. A phase II trial of cisplatin (C), gemcitabine (G) and gefitinib for advanced urothelial tract carcinoma: Results of Cancer and Leukemia Group B (CALGB) 90102. Ann Oncol 2009;20(6):1074-1079
-
(2009)
Ann. Oncol.
, vol.20
, Issue.6
, pp. 1074-1079
-
-
Philips, G.K.1
Halabi, S.2
Sanford, B.L.3
-
82
-
-
34250218955
-
Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: Results of a multicenter phase II National Cancer Institute trial
-
Hussain MH, MacVicar GR, Petrylak DP, et al. Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: Results of a multicenter phase II National Cancer Institute trial. J Clin Oncol 2007;25:2218-2224
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 2218-2224
-
-
Hussain, M.H.1
MacVicar, G.R.2
Petrylak, D.P.3
-
83
-
-
67649579849
-
A single-Arm, multicenter, open-label phase 2 study of lapatinib as the second-line treatment of patients with locally advanced or metastatic transitional cell carcinoma
-
Wulfing C, Machiels JP, Richel DJ, et al. A single-Arm, multicenter, open-label phase 2 study of lapatinib as the second-line treatment of patients with locally advanced or metastatic transitional cell carcinoma. Cancer 2009;115:2881-2890
-
(2009)
Cancer
, vol.115
, pp. 2881-2890
-
-
Wulfing, C.1
Machiels, J.P.2
Richel, D.J.3
-
84
-
-
79958168255
-
Oncogenic role of fibroblast growth factor receptor 3 in tumorigenesis of urinary bladder cancer
-
Available online 6 September 2010. PMID: 20822928
-
Pandith AA, Shah ZA, Siddiqi MA. Oncogenic role of fibroblast growth factor receptor 3 in tumorigenesis of urinary bladder cancer. Urol Oncol 2010 Available online 6 September 2010. PMID: 20822928
-
(2010)
Urol. Oncol.
-
-
Pandith, A.A.1
Shah, Z.A.2
Siddiqi, M.A.3
-
85
-
-
66349135677
-
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
-
Qing J, Du X, Chen Y, et al. Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Investig 2009;119:1216-1229
-
(2009)
J. Clin. Investig.
, vol.119
, pp. 1216-1229
-
-
Qing, J.1
Du, X.2
Chen, Y.3
-
86
-
-
77249137893
-
1-Tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino) -pyr ido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest
-
Miyake M, Ishii M, Koyama N, et al. 1-Tert-butyl-3-[6-(3,5-dimethoxy- phenyl)-2-(4-diethylamino-butylamino)-pyr ido[2,3-d]pyrimidin-7-yl]-urea (PD173074), a selective tyrosine kinase inhibitor of fibroblast growth factor receptor-3 (FGFR3), inhibits cell proliferation of bladder cancer carrying the FGFR3 gene mutation along with up-regulation of p27/Kip1 and G1/G0 arrest. J Pharmacol Exp Ther 2010;332:795-802
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 795-802
-
-
Miyake, M.1
Ishii, M.2
Koyama, N.3
-
87
-
-
78650875209
-
Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo
-
Lamont FR, Tomlinson DC, Cooper PA, et al. Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo. Br J Cancer 2011;104:75-82
-
(2011)
Br. J. Cancer
, vol.104
, pp. 75-82
-
-
Lamont, F.R.1
Tomlinson, D.C.2
Cooper, P.A.3
-
88
-
-
49849098119
-
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies
-
Garcia JA, Danielpour D. Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. Mol Cancer Ther 2008;7:1347-1354
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1347-1354
-
-
Garcia, J.A.1
Danielpour, D.2
-
89
-
-
77953180987
-
Mammalian target of rapamycin (Mtor) regulates cellular proliferation and tumor growth in urothelial carcinoma
-
Hansel DE, Platt E, Orloff M, et al. Mammalian target of rapamycin (Mtor) regulates cellular proliferation and tumor growth in urothelial carcinoma. Am J Pathol 2010;176:3062-3072
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 3062-3072
-
-
Hansel, D.E.1
Platt, E.2
Orloff, M.3
-
90
-
-
79955505851
-
Effects of Mtor inhibitor everolimus (RAD001) on bladder cancer cells
-
Chiong E, Lee IL, Dadbin A, et al. Effects of Mtor inhibitor everolimus (RAD001) on bladder cancer cells. Clin Cancer Res 2011;17:2863-2873
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 2863-2873
-
-
Chiong, E.1
Lee, I.L.2
Dadbin, A.3
-
92
-
-
84860247115
-
Final results of a phase II study of everolimus (RAD001) in metastatic transitional cell carcinoma (TCC) of the urothelium
-
Suppl):abstract
-
Milowsky MI, Regazzi AM, Garcia-Grossman IR, et al. Final results of a phase II study of everolimus (RAD001) in metastatic transitional cell carcinoma (TCC) of the urothelium. J Clin Oncol 2011;29(Suppl):abstract 4606
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4606
-
-
Milowsky, M.I.1
Regazzi, A.M.2
Garcia-Grossman, I.R.3
-
93
-
-
78449243490
-
Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy
-
Callahan MK, Wolchok JD, Allison JP. Anti-CTLA-4 antibody therapy: Immune monitoring during clinical development of a novel immunotherapy. Semin Oncol 2010;37:473-484
-
(2010)
Semin. Oncol.
, vol.37
, pp. 473-484
-
-
Callahan, M.K.1
Wolchok, J.D.2
Allison, J.P.3
-
94
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011;364:2517-2526
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
95
-
-
77952337834
-
Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial
-
Carthon BC, Wolchok JD, Yuan J, et al. Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 2010;16:2861-2871
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
-
96
-
-
0025761943
-
Human chorionic gonadotropin expression by bladder cancers: Biology and clinical potential
-
Iles RK, Chard T. Human chorionic gonadotropin expression by bladder cancers: Biology and clinical potential. J Urol 1991;145:453-458
-
(1991)
J. Urol.
, vol.145
, pp. 453-458
-
-
Iles, R.K.1
Chard, T.2
-
97
-
-
79959545223
-
Phase I study utilizing a novel antigen-presenting cell-Targeted vaccine with Toll-like receptor stimulation to induce immunity to self-Antigens in cancer patients
-
Morse MA, Chapman R, Powderly J, et al. Phase I study utilizing a novel antigen-presenting cell-Targeted vaccine with Toll-like receptor stimulation to induce immunity to self-Antigens in cancer patients. Clin Cancer Res 2011;17:4844-4853
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 4844-4853
-
-
Morse, M.A.1
Chapman, R.2
Powderly, J.3
-
98
-
-
79959569674
-
CDX-1307: A novel vaccine under study as treatment for muscle-invasive bladder cancer
-
Morse MA, Bradley DA, Keler T, et al. CDX-1307: A novel vaccine under study as treatment for muscle-invasive bladder cancer. Expert Rev Vaccines 2011;10:733-742
-
(2011)
Expert Rev. Vaccines
, vol.10
, pp. 733-742
-
-
Morse, M.A.1
Bradley, D.A.2
Keler, T.3
-
99
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010;363:411-422
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
100
-
-
77952174698
-
Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling
-
Levitt JM, Yamashita H, Jian W, et al. Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling. Mol Cancer Ther 2010;9:1128-1135
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 1128-1135
-
-
Levitt, J.M.1
Yamashita, H.2
Jian, W.3
-
101
-
-
77953190164
-
The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-Activated protein kinase-dependent activation of paxillin
-
Metalli D, Lovat F, Tripodi F, et al. The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-Activated protein kinase-dependent activation of paxillin. Am J Pathol 2010;176:2997-3006
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 2997-3006
-
-
Metalli, D.1
Lovat, F.2
Tripodi, F.3
-
102
-
-
77950552463
-
Targeting the HGF/Met signalling pathway in cancer
-
Cecchi F, Rabe DC, Bottaro DP. Targeting the HGF/Met signalling pathway in cancer. Eur J Cancer 2010;46:1260-1270
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 1260-1270
-
-
Cecchi, F.1
Rabe, D.C.2
Bottaro, D.P.3
-
103
-
-
32944481043
-
Phase I and pharmacokinetics trial of ABI-007, a novel nanoparticle formulation of paclitaxel in patients with advanced nonhematologic malignancies
-
Nyman DW, Campbell KJ, Hersh E, et al. Phase I and pharmacokinetics trial of ABI-007, a novel nanoparticle formulation of paclitaxel in patients with advanced nonhematologic malignancies. J Clin Oncol 2005;23:7785-7793
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 7785-7793
-
-
Nyman, D.W.1
Campbell, K.J.2
Hersh, E.3
-
104
-
-
84906802175
-
-
Princess Margaret Hospital, Toronto, ON, Canada; Ottawa Regional Cancer Center, Ottawa, ON, Canada; Juravinski Cancer Centre, Hamilton, ON, Canada; London Regional Cancer Centre, London, ON, Canada; Sunnybrook Odette Cancer Centre, Toronto, ON, Canada A phase II study of single-Agent nab-paclitaxel as second-line therapy in patients with metastatic urothelial carcinoma.
-
Sridhar SS, Canil CM, Mukherjee SD, et al. Princess Margaret Hospital, Toronto, ON, Canada; Ottawa Regional Cancer Center, Ottawa, ON, Canada; Juravinski Cancer Centre, Hamilton, ON, Canada; London Regional Cancer Centre, London, ON, Canada; Sunnybrook Odette Cancer Centre, Toronto, ON, Canada A phase II study of single-Agent nab-paclitaxel as second-line therapy in patients with metastatic urothelial carcinoma. Presented at the Proceedings of the 2010 Genitourinary Cancers Symposium; 2010
-
(2010)
Presented at the Proceedings of the 2010 Genitourinary Cancers Symposium
-
-
Sridhar, S.S.1
Canil, C.M.2
Mukherjee, S.D.3
-
105
-
-
84906797379
-
A phase II trial of neoadjuvant ABI-007 carboplatin and gemcitabine (ACG) in patients with locally advanced carcinoma of the bladder [abstract 244]
-
Smith DC, Grivas P, Daignault S, et al. A phase II trial of neoadjuvant ABI-007, carboplatin and gemcitabine (ACG) in patients with locally advanced carcinoma of the bladder [abstract 244]. Genitourinary cancer symposium; 2011
-
(2011)
Genitourinary Cancer Symposium
-
-
Smith, D.C.1
Grivas, P.2
Daignault, S.3
-
106
-
-
84856341746
-
Eribulin mesylate a novel microtubule inhibitor in the treatment of breast cancer
-
Cortes J, Montero AJ, Gluck S. Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer. Cancer Treat Rev 2012;38(2):143-151
-
(2012)
Cancer Treat Rev.
, vol.38
, Issue.2
, pp. 143-151
-
-
Cortes, J.1
Montero, A.J.2
Gluck, S.3
-
107
-
-
79952487463
-
Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): A phase 3 open-label randomised study
-
Cortes J, O'Shaughnessy J, Loesch D, et al. Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): A phase 3 open-label randomised study. Lancet 2011;377:914-923
-
(2011)
Lancet
, vol.377
, pp. 914-923
-
-
Cortes, J.1
O'Shaughnessy, J.2
Loesch, D.3
-
108
-
-
84906804215
-
-
California Cancer Consortium; University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, CA; University of Texas M. D. Anderson Cancer Center, Houston, TX; University of Southern California, Los Angeles, CA; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA; City of Hope, Duarte, CA University of Chicago, Chicago, IL; University of California, Davis, Sacramento, CA Phase II study of eribulin E7389) in patients (pts) with advanced urothelial cancer (UC)-Final report: A California Cancer Consortium-led NCI/CTEP-sponsored trial.
-
Quinn DI, Aparicio A, Tsao-Wei DD, et al. California Cancer Consortium; University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, CA; University of Texas M. D. Anderson Cancer Center, Houston, TX; University of Southern California, Los Angeles, CA; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA; City of Hope, Duarte, CA; University of Chicago, Chicago, IL; University of California, Davis, Sacramento, CA Phase II study of eribulin (E7389) in patients (pts) with advanced urothelial cancer (UC)-Final report: A California Cancer Consortium-led NCI/CTEP-sponsored trial. Presented at the 2010 ASCO Annual Meeting; 2010
-
(2010)
Presented at the 2010 ASCO Annual Meeting
-
-
Quinn, D.I.1
Aparicio, A.2
Tsao-Wei, D.D.3
-
109
-
-
33847681504
-
Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy
-
Bellmunt J, Paz-Ares L, Cuello M, et al. Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy. Ann Oncol 2007;18:522-528
-
(2007)
Ann. Oncol.
, vol.18
, pp. 522-528
-
-
Bellmunt, J.1
Paz-Ares, L.2
Cuello, M.3
-
111
-
-
77958049428
-
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
-
53ra75
-
Dedes KJ, Wetterskog D, Mendes-Pereira AM, et al. PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors. Sci Transl Med 2010;2:53ra75
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Dedes, K.J.1
Wetterskog, D.2
Mendes-Pereira, A.M.3
-
112
-
-
81255185302
-
Interdependent genotoxic mechanisms of monomethylarsonous acid: Role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells
-
Wnek SM, Kuhlman CL, Camarillo JM, et al. Interdependent genotoxic mechanisms of monomethylarsonous acid: Role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells. Toxicol Appl Pharmacol 2011;257:1-13
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.257
, pp. 1-13
-
-
Wnek, S.M.1
Kuhlman, C.L.2
Camarillo, J.M.3
-
113
-
-
78650376422
-
BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer
-
Font A, Taron M, Gago JL, et al. BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer. Ann Oncol 2011;22:139-144
-
(2011)
Ann. Oncol.
, vol.22
, pp. 139-144
-
-
Font, A.1
Taron, M.2
Gago, J.L.3
-
114
-
-
34249984161
-
Efficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma
-
Sonpavde G, Okuno N, Weiss H, et al. Efficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma. Urology 2007;69:1221-1226
-
(2007)
Urology
, vol.69
, pp. 1221-1226
-
-
Sonpavde, G.1
Okuno, N.2
Weiss, H.3
-
115
-
-
33745187848
-
Expression of estrogen receptors-Alpha and -beta in bladder cancer cell lines and human bladder tumor tissue
-
Shen SS, Smith CL, Hsieh JT, et al. Expression of estrogen receptors-Alpha and -beta in bladder cancer cell lines and human bladder tumor tissue. Cancer 2006;106:2610-2616
-
(2006)
Cancer
, vol.106
, pp. 2610-2616
-
-
Shen, S.S.1
Smith, C.L.2
Hsieh, J.T.3
-
116
-
-
43049129660
-
Phase II study of bortezomib in patients with previously treated advanced urothelial tract transitional cell carcinoma: CALGB 90207
-
Rosenberg JE, Halabi S, Sanford BL, et al. Phase II study of bortezomib in patients with previously treated advanced urothelial tract transitional cell carcinoma: CALGB 90207. Ann Oncol 2008;19:946-950
-
(2008)
Ann. Oncol.
, vol.19
, pp. 946-950
-
-
Rosenberg, J.E.1
Halabi, S.2
Sanford, B.L.3
-
117
-
-
4444235841
-
The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo
-
Kamat AM, Karashima T, Davis DW, et al. The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo. Mol Cancer Ther 2004;3:279-290
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 279-290
-
-
Kamat, A.M.1
Karashima, T.2
Davis, D.W.3
-
118
-
-
84906799311
-
California cancer consortium phase II study of vorinostat (suberoylanilide hydroxamic acid saha) in patients with advanced transitional cell urothelial cancer (TCC) after platinum-based therapy-California cancer consortium/ university of pittsburgh nci/ctep-sponsored trial
-
Cheung EM, Quinn DI, Tsao-Wei DD, et al. California Cancer Consortium Phase II study of vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in patients with advanced transitional cell urothelial cancer (TCC) after platinum-based therapy-California Cancer Consortium/University of Pittsburgh NCI/CTEP-sponsored trial. Presented at the 2008 ASCO Annual Meeting; 2008
-
(2008)
Presented at the 2008 ASCO Annual Meeting
-
-
Cheung, E.M.1
Quinn, D.I.2
Tsao-Wei, D.D.3
-
119
-
-
84860242308
-
Clinical outcome of single agent volasertib (BI 6727) as second-line treatment of patients (pts) with advanced or metastatic urothelial cancer
-
(Suppl):abstract
-
Stadler WM, Vaughn DJ, Sonpavde G, et al. Clinical outcome of single agent volasertib (BI 6727) as second-line treatment of patients (pts) with advanced or metastatic urothelial cancer. J Clin Oncol 2011;29(Suppl):abstract 4567
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4567
-
-
Stadler, W.M.1
Vaughn, D.J.2
Sonpavde, G.3
-
120
-
-
70350536600
-
Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy
-
Williams PD, Cheon S, Havaleshko DM, et al. Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy. Cancer Res 2009;69:8302-8309
-
(2009)
Cancer Res.
, vol.69
, pp. 8302-8309
-
-
Williams, P.D.1
Cheon, S.2
Havaleshko, D.M.3
-
121
-
-
20244368343
-
Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling
-
Takata R, Katagiri T, Kanehira M, et al. Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling. Clin Cancer Res 2005;11:2625-2636
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2625-2636
-
-
Takata, R.1
Katagiri, T.2
Kanehira, M.3
-
122
-
-
33751345359
-
Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy
-
Takata R, Katagiri T, Kanehira M, et al. Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy. Cancer Sci 2007;98:113-117
-
(2007)
Cancer Sci.
, vol.98
, pp. 113-117
-
-
Takata, R.1
Katagiri, T.2
Kanehira, M.3
-
123
-
-
78650376422
-
BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer
-
Font A, Taron M, Gago JL, et al. BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer. Ann Oncol 2011;22:139-144
-
(2011)
Ann. Oncol.
, vol.22
, pp. 139-144
-
-
Font, A.1
Taron, M.2
Gago, J.L.3
-
124
-
-
60549084195
-
Detection of circulating tumor cells in patients with urothelial cancer
-
Gallagher DJ, Milowsky MI, Ishill N, et al. Detection of circulating tumor cells in patients with urothelial cancer. Ann Oncol 2009;20:305-308
-
(2009)
Ann. Oncol.
, vol.20
, pp. 305-308
-
-
Gallagher, D.J.1
Milowsky, M.I.2
Ishill, N.3
-
125
-
-
83455191894
-
Germline single-nucleotide polymorphisms (SNPs) associated with response of urothelial carcinoma (UC) to platinum-based therapy: The role of the host
-
:abstract
-
Gallagher D, Joseph V, Garcia-Grossman IR, et al. Germline single-nucleotide polymorphisms (SNPs) associated with response of urothelial carcinoma (UC) to platinum-based therapy: The role of the host. J Clin Oncol 2011;29(Suppl 7):abstract 236
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.7
, pp. 236
-
-
Gallagher, D.1
Joseph, V.2
Garcia-Grossman, I.R.3
-
127
-
-
33746298622
-
Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder
-
Dash A, Galsky MD, Vickers AJ, et al. Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder. Cancer 2006;107:506-513
-
(2006)
Cancer
, vol.107
, pp. 506-513
-
-
Dash, A.1
Galsky, M.D.2
Vickers, A.J.3
-
128
-
-
77957597563
-
First-line systemic therapy trials for advanced transitional-cell carcinoma of the urothelium should we stop separating cisplatin-eligible and -ineligible patients
-
author reply e443-e444
-
Sonpavde G, Galsky MD, Vogelzang NJ. First-line systemic therapy trials for advanced transitional-cell carcinoma of the urothelium: Should we stop separating cisplatin-eligible and -ineligible patients? J Clin Oncol 2010;28:e441-2.author reply e443-e444
-
(2010)
J Clin. Oncol.
, vol.28
-
-
Sonpavde, G.1
Galsky, M.D.2
Vogelzang, N.J.3
-
129
-
-
77956191168
-
Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium
-
Sonpavde G, Sternberg CN, Rosenberg JE, et al. Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium. Lancet Oncol 2010;11:861-870
-
(2010)
Lancet Oncol.
, vol.11
, pp. 861-870
-
-
Sonpavde, G.1
Sternberg, C.N.2
Rosenberg, J.E.3
-
130
-
-
77952303284
-
Suggestions for regulatory agency approval of second-line systemic therapy for metastatic transitional cell carcinoma
-
author reply e208
-
Sonpavde G, Rosenberg JE, Hahn NM, et al. Suggestions for regulatory agency approval of second-line systemic therapy for metastatic transitional cell carcinoma. J Clin Oncol 2010;28:e205-7.author reply e208
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Sonpavde, G.1
Rosenberg, J.E.2
Hahn, N.M.3
-
131
-
-
70249128736
-
Final results of sequential doxorubicin plus gemcitabine and ifosfamide, paclitaxel, and cisplatin chemotherapy in patients with metastatic or locally advanced transitional cell carcinoma of the urothelium
-
Milowsky MI, Nanus DM, Maluf FC, et al. Final results of sequential doxorubicin plus gemcitabine and ifosfamide, paclitaxel, and cisplatin chemotherapy in patients with metastatic or locally advanced transitional cell carcinoma of the urothelium. J Clin Oncol 2009;27:4062-4067
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4062-4067
-
-
Milowsky, M.I.1
Nanus, D.M.2
Maluf, F.C.3
-
132
-
-
33750585961
-
Sequential gemcitabine and cisplatin followed by docetaxel as first-line treatment of advanced urothelial carcinoma: A multicenter phase II study of the hellenic oncology research group
-
Boukovinas I, Androulakis N, Vamvakas L, et al. Sequential gemcitabine and cisplatin followed by docetaxel as first-line treatment of advanced urothelial carcinoma: A multicenter phase II study of the Hellenic Oncology Research Group. Ann Oncol 2006;17:1687-1692
-
(2006)
Ann. Oncol.
, vol.17
, pp. 1687-1692
-
-
Boukovinas, I.1
Androulakis, N.2
Vamvakas, L.3
-
133
-
-
84906805464
-
Sunitinib in BCG-refractory non-muscle-invasive transitional cell carcinoma of the bladder
-
abstract
-
Garcia JA, Stephenson AJ, Ireland J, et al. Sunitinib in BCG-refractory non-muscle-invasive transitional cell carcinoma of the bladder. J Clin Oncol 2011;29(Suppl 7):abstract 262
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.7
, pp. 262
-
-
Garcia, J.A.1
Stephenson, A.J.2
Ireland, J.3
|