Validity, significance, strengths, limitations, and evidentiary value of real-world clinical data for combination therapy in Alzheimer's disease: Comparison of efficacy and effectiveness studies

Neurodegenerative Diseases

Volumn 10, Issue 1-4, 2012, Pages 170-174

  Atri, Alireza ^a,b,c   Rountree, Susan D ^d   Lopez, Oscar L ^e   Doody, Rachelle S ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Comparative effectiveness; Dementia treatment; Donepezil; Evidence grade; Galantamine; Memantine; Observational trial; Rivastigmine

Indexed keywords

CHOLINESTERASE INHIBITOR; DONEPEZIL; MEMANTINE; PLACEBO;

ALZHEIMER DISEASE; ARTICLE; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; COST; DATA COLLECTION METHOD; DRUG EFFICACY; EXTERNAL VALIDITY; FUNCTIONAL STATUS; HOSPITAL ADMISSION; HUMAN; LONG TERM CARE; LONG TERM OBSERVATIONAL CONTROLLED STUDY; MONOTHERAPY; NURSING HOME; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESEARCH ETHICS; SYSTEMATIC REVIEW; TREATMENT OUTCOME;

ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; COHORT STUDIES; DATABASES, BIBLIOGRAPHIC; DRUG THERAPY, COMBINATION; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; MEMANTINE; MENTAL STATUS SCHEDULE; META-ANALYSIS AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REPRODUCIBILITY OF RESULTS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84860222723     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000335156     Document Type: Article

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