A meta-analysis evaluating stereotactic radiosurgery, whole-brain radiotherapy, or both for patients presenting with a limited number of brain metastases

Cancer

Volumn 118, Issue 9, 2012, Pages 2486-2493

  Tsao, May ^a   Xu, Wei ^b   Sahgal, Arjun ^a,c  

^a DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

brain metastases; meta analysis; neurocognition; stereotactic radiosurgery; whole brain radiotherapy

Indexed keywords

APHASIA; ARTICLE; BLOOD BRAIN BARRIER; BRAIN METASTASIS; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CAUSE OF DEATH; CLINICAL EFFECTIVENESS; COGNITION; CONSCIOUSNESS DISORDER; DISTANT BRAIN CONTROL; HOPKINS VERBAL LEARNING TEST; HUMAN; INTERMETHOD COMPARISON; LEUKOENCEPHALOPATHY; LOCAL CONTROL; MENTAL PERFORMANCE; META ANALYSIS; MINI MENTAL STATE EXAMINATION; MONOTHERAPY; MOTOR NEUROPATHY; NEUROLOGIC DISEASE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PSYCHOLOGIC TEST; QUALITY OF LIFE; RADIATION NECROSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEIZURE; STEREOTACTIC RADIOSURGERY; SYSTEMATIC REVIEW; WHOLE BRAIN RADIOTHERAPY;

BRAIN NEOPLASMS; COGNITION; COMBINED MODALITY THERAPY; HUMANS; QUALITY OF LIFE; RADIOSURGERY; TREATMENT OUTCOME;

EID: 84860222241     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26515     Document Type: Article

References (16)

1. Gaspar L, Scott C, Rotman M, et al. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys. 1997; 37: 745-751.
2. Sperduto PW, Chao ST, Sneed PK, et al. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. Int J Radiat Oncol Biol Phys. 2010; 77: 655-661.
3. Borgelt B, Gelber R, Kramer S, et al. The palliation of brain metastases: final results of the first two studies by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1980; 6: 1-9.
4. Sahgal A, Ma L, Chang E, et al. Advances in technology for intracranial stereotactic radiosurgery. Technol Cancer Res Treat. 2009; 8: 271-280.
5. Andrews DW, Scott CB, Sperduto PW, et al. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet. 2004; 363: 1665-1672.
6. Kondziolka D, Patel A, Lunsford LD, Kassam A, Flickinger JC,. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int J Radiat Oncol Biol Phys. 1999; 45: 427-434.
7. Aoyama H, Shirato H, Tago M, et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA. 2006; 295: 2483-2491.
8. Chang EL, Wefel JS, Hess KR, et al. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol. 2009; 10: 1037-1044.
9. Kocher M, Soffietti R, Abacioglu U, et al. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol. 2010; 29: 134-141.
10. Roos DE, Wirth A, Burmeister BH, et al. Whole brain irradiation following surgery or radiosurgery for solitary brain metastases: mature results of a prematurely closed randomized Trans-Tasman Radiation Oncology Group trial (TROG 98.05). Radiother Oncol. 2006; 80: 318-322.
11. Parmar MK, Torri V, Stewart L,. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med. 1998; 17: 2815-2834.
12. Meyers CA, Wefel JS,. The use of the mini-mental state examination to assess cognitive functioning in cancer trials: no ifs, ands, buts, or sensitivity. J Clin Oncol. 2003; 21: 3557-3558.
13. Slotman B, Faivre-Finn C, Kramer G, et al. Prophylactic cranial irradiation in extensive small-cell lung cancer. N Engl J Med. 2007; 357: 664-672.
14. Auperin A, Arriagada R, Pignon JP, et al. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med. 1999; 341: 476-484.
15. Gore EM, Bae K, Wong SJ, et al. Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: primary analysis of radiation therapy oncology group study RTOG 0214. J Clin Oncol. 2011; 29: 272-278.
16. Sun A, Bae K, Gore EM, et al. Phase III trial of prophylactic cranial irradiation compared with observation in patients with locally advanced non-small-cell lung cancer: neurocognitive and quality-of-life analysis. J Clin Oncol. 2011; 29: 279-286.