Delivery of a DNA vaccine for Alzheimer's disease by electroporation versus gene gun generates potent and similar immune responses

Neurodegenerative Diseases

Volumn 10, Issue 1-4, 2012, Pages 261-264

  Davtyan, Hayk ^a,b   Ghochikyan, Anahit ^a   Movsesyan, Nina ^b   Ellefsen, Barry ^d   Petrushina, Irina ^b   Cribbs, David H ^b,c   Hannaman, Drew ^d   Evans, Claire F ^d   Agadjanyan, Michael G ^a,b  

^a INSTITUTE FOR MOLECULAR MEDICINE   (United States)

^b Institute for Memory Impairments and Neurological Disorders   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Ichor Medical Systems Inc   (United States)

Author keywords

Alzheimer's disease; DNA epitope vaccine; Electroporation; Gene gun; Immune responses

Indexed keywords

AMYLOID BETA PROTEIN ANTIBODY; AMYLOID BETA PROTEIN[1-42]; DNA VACCINE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANTIBODY RESPONSE; ANTIGEN BINDING; BRAIN TISSUE; CELLULAR IMMUNITY; DNA IMMUNIZATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SCREENING; ELECTROPORATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; GENE GUN; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; TRANSLATIONAL RESEARCH;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIBODIES; BIOLISTICS; DISEASE MODELS, ANIMAL; ELECTROPORATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; MALARIA VACCINES; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; THYMIDINE; TIME FACTORS; TRITIUM; VACCINES, DNA;

EID: 84860220147     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000333359     Document Type: Review

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