Inhibition of amyloid precursor protein beta-secretase cleavage site affects survival and motor functions of amyotrophic lateral sclerosis transgenic mice

Neurodegenerative Diseases

Volumn 10, Issue 1-4, 2012, Pages 30-33

  Rabinovich Toidman, Polina ^a   Becker, Maria ^a   Barbiro, Beika ^a   Solomon, Beka ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Secretase cleavage; Amyloid precursor protein; Amyotrophic lateral sclerosis; Motor function; Survival

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; MONOCLONAL ANTIBODY; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; MALE; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SURVIVAL;

AGE FACTORS; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIBODIES, MONOCLONAL; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; ROTAROD PERFORMANCE TEST; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84860217270     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000334774     Document Type: Article

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