Noninvasive, quantitative analysis of drug mixtures in containers using spatially offset raman spectroscopy (SORS) and multivariate statistical analysis

Applied Spectroscopy

Volumn 66, Issue 5, 2012, Pages 530-537

  Olds, William J ^a   Sundarajoo, Shankaran ^a   Selby, Mark ^a   Cletus, Biju ^a   Fredericks, Peter M ^a   Izake, Emad L ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Drug mixtures; Forensic analysis; Partial least squares; PCA; Pharmaceutical analysis; PLS; Principal component analysis; Quantitative analysis; SORS; Spatially offset Raman spectroscopy

Indexed keywords

FORENSIC ANALYSIS; PARTIAL LEAST SQUARE (PLS); PCA; PHARMACEUTICAL ANALYSIS; PLS; SORS;

CHEMICAL ANALYSIS; DRUG PRODUCTS; GLUCOSE; MULTIVARIANT ANALYSIS; PLASTIC CONTAINERS; PRINCIPAL COMPONENT ANALYSIS; RAMAN SCATTERING; RAMAN SPECTROSCOPY;

MIXTURES;

CAFFEINE; COUNTERFEIT DRUG; PARACETAMOL; PHENYLEPHRINE; STREET DRUG;

ARTICLE; DRUG MIXTURE; FORENSIC SCIENCE; METHODOLOGY; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; RAMAN SPECTROMETRY; REGRESSION ANALYSIS;

ACETAMINOPHEN; CAFFEINE; COMPLEX MIXTURES; COUNTERFEIT DRUGS; FORENSIC SCIENCES; LEAST-SQUARES ANALYSIS; MULTIVARIATE ANALYSIS; PHENYLEPHRINE; PRINCIPAL COMPONENT ANALYSIS; SPECTRUM ANALYSIS, RAMAN; STREET DRUGS;

EID: 84860199901     PISSN: 00037028     EISSN: None     Source Type: Journal    
DOI: 10.1366/11-06554     Document Type: Article

References (24)

1. E. Izake. "Forensic and homeland security applications of modern portable Raman spectroscopy". Forensic Sci. Int. 2010. 202(1-3): 1-8.
2. P. Matousek. "Deep non-invasive Raman spectroscopy of living tissue and powders". Chem. Soc. Rev: 2007. 36(8): 1292-1304.
3. C. Ricci, C. Eliasson, N.A. Macleod, P.N. Newton, P. Matousek, S.G. Kazarian. "Characterization of genuine and fake artesunate anti-malarial tablets using Fourier transform infrared imaging and spatially offset Raman spectroscopy through blister packs". Anal. Bioanal. Chem. 2007. 389(5): 1525-1532. (Pubitemid 350023676)
4. C. Eliasson, P. Matousek. "Noninvasive Authentication of Pharmaceutical Products through Packaging Using Spatially Offset Raman Spectroscopy". Anal. Chem. 2007. 79(4): 1696-1701.
5. P. Matousek, A.W. Parker. "Non-invasive probing of pharmaceutical capsules using transmission Raman spectroscopy". J. Raman Spectrosc. 2007. 38(5): 563-567.
6. P.N. Newton, M.D. Green, F.M. Fernández, N.P.J. Day, N.J. White. "Counterfeit anti-infective drugs". Lancet. Infect. Dis. 2006. 6(9): 602-613.
7. C.J. Strachan, T. Rades, K.C. Gordon, J. Rantanen. "Raman spectroscopy for quantitative analysis of pharmaceutical solids". J. Pharm. Pharmacol. 2007. 59(2): 179-192. (Pubitemid 46203057)
8. M. Pelletier. Analytical applications of Raman spectroscopy. New York: Wiley-Blackwell, 1999.
9. K.Y. Noonan, L.A. Tonge, O.S. Fenton, D.B. Damiano, K.A. Frederick. "Rapid Classification of Simulated Street Drug Mixtures Using Raman Spectroscopy and Principal Component Analysis". Appl. Spectrosc. 2009. 63(7): 742-747.
10. C. Eliasson, N.A. Macleod, L.C. Jayes, F.C. Clarke, S.V. Hammond, M.R. Smith, P. Matousek. "Non-invasive quantitative assessment of the content of pharmaceutical capsules using transmission Raman spectroscopy". J. Pharm. Biomed. Anal. 2008. 47(2): 221-229.
11. A.G. Ryder, G. O'Connor, T.J. Glynn. "Identifications and Quantitative Measurements of Narcotics in Solid Mixtures Using Near-IR Raman Spectroscopy and Multivariate Analysis". J. Forensic Sci. 1999. 44(5): 1013-1019. (Pubitemid 29420387)
12. A.G. Ryder, G.M. O'Connor, T.J. Glynn. "Quantitative analysis of cocaine in solidmixtures using Raman spectroscopy and chemometric methods". J. Raman Spectrosc. 2000. 31(3): 221-227.
13. O.S. Fenton, L.A. Tonge, T.H. Moot, K.A. Frederick. "Quantitative Analysis of Simulated Illicit Street-Drug Samples Using Raman Spectroscopy and Partial Least Squares Regression". Spectrosc. Lett. 2011. 44(4): 229-234.
14. P. Matousek, I.P. Clark, E.R.C. Draper, M.D. Morris, A.E. Goodship, N. Everall, M. Towrie, W.F. Finney, A.W. Parker. "Subsurface Probing in Diffusely Scattering Media Using Spatially Offset Raman Spectroscopy". Appl. Spectrosc. 2005. 59(4): 393-400. (Pubitemid 40538304)
15. P. Matousek. "Inverse Spatially Offset Raman Spectroscopy for Deep Noninvasive Probing of Turbid Media". Appl. Spectrosc. 2006. 60(11): 1341-1347. (Pubitemid 44876070)
16. M.V. Schulmerich, K.A. Dooley, M.D. Morris, T.M. Vanasse, S.A. Goldstein. "Transcutaneous fiber optic Raman spectroscopy of bone using annular illumination and a circular array of collection fibers". J. Biomed. Opt. 11, 6, 060502, 2006.
17. B.B. Das, F. Liu, R.R. Alfano. "Time-resolved fluorescence and photon migration studies in biomedical and model random media". Rep. Prog. Phys. 1997. 60(2): 227-292. (Pubitemid 127494945)
18. W.J. Olds, E. Jaatinen, P. Fredericks, B. Cletus, H. Panayiotou, E.L. Izake. "Spatially offset Raman spectroscopy (SORS) for the analysis and detection of packaged pharmaceuticals and concealed drugs". Forensic Sci. Int. 2011. 212: 69-77.
19. P. Matousek, A.W. Parker. "Bulk Raman Analysis of Pharmaceutical Tablets." Appl. Spectrosc. 2006. 60(12): 1353-1357. (Pubitemid 46034501)
20. B. Cletus, W. Olds, E.L. Izake, P.M. Fredericks, H. Panayiotou, E. Jaatinen. "Toward non-invasive detection of concealed energetic materials in-field under ambient-light conditions". In: M.A. Druy, R.A. Crocombe, editors. Next-Generation Spectroscopic Technologies IV. Orlando, USA: SPIE, 2011. Vol. 8032, p. 80320I.
21. M. Bloomfield, P.W. Loeffen, P. Matousek. "Detection of concealed substances in sealed opaque plastic and coloured glass containers using SORS". In: C. Lewis, D. Burgess, R. Zamboni, F. Kajzar, E.M. Heckman, editors. Optics and Photonics for Counterterrorism and Crime Fighting VI and Optical Materials in Defence Systems Technology VII. Toulouse, France: SPIE, 2010. Vol. 7838, p. 783808-15. doi: 10.1117/12.874724.
22. M.D. Hargreaves, P. Matousek. "Threat detection of liquid explosive precursor mixtures by Spatially Offset Raman Spectroscopy (SORS)". In: C. Lewis, editor. Optics and Photonics for Counterterrorism and Crime Fighting V. Berlin, Germany: SPIE, 2009. Vol. 7486, p. 74860B.
23. P.W. Loeffen, G. Maskall, S. Bonthron, M. Bloomfield, C. Tombling, P. Matousek. "Chemical and explosives point detection through opaque containers using spatially offset Raman spectroscopy (SORS)". In: A.W. Fountain, III, P.J. Gardner, editors. Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XII. Orlando, USA: SPIE, 2011. Vol. 8018, p. 80181E-1.
24. P.J. Gemperline. "Principal Component Analysis". In: P.J. Gemperline, editor. Practical Guide to Chemometrics. Boca Raton: CRC/Taylor & Francis, 2006. P. 86.