Magnetic nanoparticles sensitize MCF-7 breast cancer cells to doxorubicin-induced apoptosis

World Journal of Surgical Oncology

Volumn 10, Issue , 2012, Pages

  Aljarrah, Khaled ^a   Mhaidat, Nizar M ^a   Al Akhras, M Ali H ^a   Aldaher, Ahmad N ^a   Albiss, B A ^a   Aledealat, Khaled ^a   Alsheyab, Fawzi M ^a  

^a JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

Breast cancer; Doxorubicin; Mcf 7; Nanoparticles

Indexed keywords

DOXORUBICIN; IRON OXIDE NANOPARTICLE; MAGNETIC NANOPARTICLE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; HUMAN; HUMAN CELL; MAGNETIC FIELD; SENSITIZATION;

APOPTOSIS; BREAST NEOPLASMS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; FERRIC COMPOUNDS; HUMANS; MAGNETICS; METAL NANOPARTICLES; TUMOR CELLS, CULTURED;

EID: 84860186424     PISSN: None     EISSN: 14777819     Source Type: Journal    
DOI: 10.1186/1477-7819-10-62     Document Type: Article

References (44)

1. Pecorelli S, Favalli G, Zigliani L, Odicino F. Cancer in women. Int J Gynaecol Obstet 2003, 82:369-379. 10.1016/S0020-7292(03)00225-X, 14499983.
2. Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer 2010, 46:765-781. 10.1016/j.ejca.2009.12.014, 20116997.
3. Desantis C, Siegel R, Bandi P, Jemal A. Breast cancer statistics, 2011. CA Cancer J Clin 2011, 2011:20134.
4. Jordan Breast Cancer Program Jordan Breast Cancer Program., http://www.jbcp.jo/node/14
5. Peng XH, Qian X, Mao H, Wang AY, Chen ZG, Nie S, Shin DM. Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy. Int J Nanomed 2008, 3:311-321.
6. Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004, 56:185-229. 10.1124/pr.56.2.6, 15169927.
7. Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med 1998, 339:900-905. 10.1056/NEJM199809243391307, 9744975.
8. Amstad E, Textor M, Reimhult E. Stabilization and functionalization of iron oxide nanoparticles for biomedical applications. Nanoscale 2011, 3:2819-2843. 10.1039/c1nr10173k, 21629911.
9. Loo C, Lowery A, Halas N, West J, Drezek R. Immunotargeted nanoshells for integrated cancer imaging and therapy. Nano Lett 2005, 5:709-711. 10.1021/nl050127s, 15826113.
10. Park SI, Kwon BJ, Park JH, Jung H, Yu KH. Synthesis and characterization of 3-[131I]iodo-L-tyrosine grafted Fe3O4@SiO2 nanocomposite for single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). SO-J Nanosci Nanotechnol 2011, 11:1818-1821.
11. Qu X, Wang J, Zhang Z, Koop N, Rahmanzadeh R, Huttmann G. Imaging of cancer cells by multiphoton microscopy using gold nanoparticles and fluorescent dyes. J Biomed Opt 2008, 13:031217. 10.1117/1.2942373, 18601541.
12. Sosnovik DE, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol 2008, 103:122-130. 10.1007/s00395-008-0710-7, 2597271, 18324368.
13. Ajima K, Yudasaka M, Murakami T, Maigne A, Shiba K, Iijima S. Carbon nanohorns as anticancer drug carriers. Mol Pharm 2005, 2:475-480. 10.1021/mp0500566, 16323954.
14. Cho K, Wang X, Nie S, Chen ZG, Shin DM. Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res 2008, 14:1310-1316. 10.1158/1078-0432.CCR-07-1441, 18316549.
15. Gong X, Peng S, Wen W, Sheng P, Li W. Design and fabrication of magnetically functionalized core/shell microspheres for smart drug delivery. Adv Funct Mater 2009, 19:292-297.
16. Souza GR, Christianson DR, Staquicini FI, Ozawa MG, Snyder EY, Sidman RL, Miller JH, Arap W, Pasqualini R. Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents. Proc Natl Acad Sci USA 2006, 103:1215-1220. 10.1073/pnas.0509739103, 1346765, 16434473.
17. Yu MK, Jeong YY, Park J, Park S, Kim JW, Min JJ, Kim K, Jon S. Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo. Angew Chem Int Ed Engl 2008, 47:5362-5365. 10.1002/anie.200800857, 18551493.
18. Chen J, Wang D, Xi J, Au L, Siekkinen A, Warsen A, Li ZY, Zhang H, Xia Y, Li X. Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells. Nano Lett 2007, 7:1318-1322. 10.1021/nl070345g, 2504471, 17430005.
19. DeNardo SJ, DeNardo GL, Miers LA, Natarajan A, Foreman AR, Gruettner C, Adamson GN, Ivkov R. Development of tumor targeting bioprobes ((111)In-chimeric L6 monoclonal antibody nanoparticles) for alternating magnetic field cancer therapy. Clin Cancer Res 2005, 11:7087s-7092s. 10.1158/1078-0432.CCR-1004-0022, 16203807.
20. Dennis CL, Jackson AJ, Borchers JA, Hoopes PJ, Strawbridge R, Foreman AR, van Lierop J, Gruttner C, Ivkov R. Nearly complete regression of tumors via collective behavior of magnetic nanoparticles in hyperthermia. Nanotechnology 2009, 20:395103. 10.1088/0957-4484/20/39/395103, 19726837.
21. Hirsch LR, Stafford RJ, Bankson JA, Sershen SR, Rivera B, Price RE, Hazle JD, Halas NJ, West JL. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci USA 2003, 100:13549-13554. 10.1073/pnas.2232479100, 263851, 14597719.
22. Liu T-Y, Liu K-H, Liu D-M, Chen S-Y, Chen I-W. Temperature-sensitive nanocapsules for controlled drug release caused by magnetically triggered structural disruption. Adv Funct Mater 2008, 18:1-8.
23. Maier-Hauff K, Rothe R, Scholz R, Gneveckow U, Wust P, Thiesen B, Feussner A, von Deimling A, Waldoefner N, Felix R, Jordan A. Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme. J Neurooncol 2007, 81:53-60.
24. Bae JE, Huh MI, Ryu BK, Do JY, Jin SU, Moon MJ, Jung JC, Chang Y, Kim E, Chi SG, Lee GH, Chae KS. The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles. Biomaterials 2011, 32:9401-9414. 10.1016/j.biomaterials.2011.08.075, 21911251.
25. Mhaidat NM, Zhang XD, Allen J, Avery-Kiejda KA, Scott RJ, Hersey P. Temozolomide induces senescence but not apoptosis in human melanoma cells. Br J Cancer 2007, 97:1225-1233. 10.1038/sj.bjc.6604017, 2360470, 17968428.
26. Gillespie SK, Zhang XD, Hersey P. Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. Mol Cancer Ther 2004, 3:1651-1658.
27. Box HC, Maccubbin AE. Lipid peroxidation and DNA damage. Nutrition 1997, 13:920-921. 10.1016/S0899-9007(97)00260-8, 9357035.
28. Meneghini R. Iron homeostasis, oxidative stress, and DNA damage. Free Radic Biol Med 1997, 23:783-792. 10.1016/S0891-5849(97)00016-6, 9296456.
29. Grzegorczyk J. Apoptosis-programmed cell death (PCD)-current conceptions. Int J Biomed Res 1999, 1:2-7.
30. Jajte JM. Chemical-induced changes in intracellular redox state and in apoptosis. Int J Occup Med Environ Health 1997, 10:203-212.
31. Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-257. 10.1038/bjc.1972.33, 2008650, 4561027.
32. Sarafian TA, Bredesen DE. Is apoptosis mediated by reactive oxygen species?. Free Radical Res 1994, 21:1-8.
33. Lai H, Singh NP. Acute exposure to a 60Hz magnetic field increases DNA strand breaks in rat brain cells. Bioelectromagnetics 1997, 18:156-165. 10.1002/(SICI)1521-186X(1997)18:2<156::AID-BEM8>3.0.CO;2-1, 9084866.
34. Singh N, Lai H. 60Hz magnetic field exposure induces DNA crosslinks in rat brain cells. Mutat Res 1998, 400:313-320. 10.1016/S0027-5107(98)00017-7, 9685689.
35. Zmyslony M, Palus J, Jajte J, Dziubaltowska E, Rajkowska E. DNA damage in rat lymphocytes treated in vitro with iron cations and exposed to 7 mT magnetic fields (static or 50Hz). Mutat Res 2000, 453:89-96. 10.1016/S0027-5107(00)00094-4, 11006416.
36. Hisamitsu T, Narita K, Kasahara T, Seto A, Yu Y, Asano K. Induction of apoptosis in human leukemic cells by magnetic fields. Jpn J Physiol 1997, 47:307-310. 10.2170/jjphysiol.47.307, 9271162.
37. Reipert BM, Allan D, Reipert S, Dexter TM. Apoptosis in haemopoietic progenitor cells exposed to extremely low-frequency magnetic fields. Life Sci 1997, 61:1571-1582. 10.1016/S0024-3205(97)00736-4, 9353166.
38. Simko M, Kriehuber R, Weiss DG, Luben RA. Effects of 50Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines. Bioelectromagnetics 1998, 19:85-91. 10.1002/(SICI)1521-186X(1998)19:2<85::AID-BEM5>3.0.CO;2-#, 9492164.
39. Blumenthal NC, Ricci J, Breger L, Zychlinsky A, Solomon H, Chen GG, Kuznetsov D, Dorfman R. Effects of low-intensity AC and/or DC electromagnetic fields on cell attachment and induction of apoptosis. Bioelectromagnetics 1997, 18:264-272. 10.1002/(SICI)1521-186X(1997)18:3<264::AID-BEM10>3.0.CO;2-P, 9096845.
40. Sarvestani AS, Abdolmaleki P, Mowla SJ, Ghanati F, Heshmati E, Tavasoli Z, Jahromi AM. Static magnetic fields aggravate the effects of ionizing radiation on cell cycle progression in bone marrow stem cells. Micron 2010, 2:101-104.
41. Chionna A, Dwikat M, Panzarini E, Tenuzzo B, Carla EC, Verri T, Pagliara P, Abbro L, Dini L. Cell shape and plasma membrane alterations after static magnetic fields exposure. Eur J Histochem 2003, 47:299-308.
42. Mhaidat NM, Alali FQ, Matalqah SM, Matalka II, Jaradat SA, Al-Sawalha NA, Thorne RF. Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78. Anticancer Drugs 2009, 20:601-606. 10.1097/CAD.0b013e32832e3120, 19521235.
43. Chow K, Tung WL. Magnetic field exposure enhances DNA repair through the induction of DnaK/J synthesis. FEBS Lett 2000, 478:133-136. 10.1016/S0014-5793(00)01822-6, 10922484.
44. Robison JG, Pendleton AR, Monson KO, Murray BK, O'Neill KL. Decreased DNA repair rates and protection from heat induced apoptosis mediated by electromagnetic field exposure. Bioelectromagnetics 2002, 23:106-112. 10.1002/bem.103, 11835257.