Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice

Biochemical Journal

Volumn 443, Issue 3, 2012, Pages 829-839

  Jeoung, Nam Ho ^a,b,d   Rahimi, Yasmeen ^a,b   Wu, Pengfei ^a,b   Lee, W N Paul ^c   Harris, Robert A ^a,b  

^a RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARBOR UCLA MEDICAL CENTER   (United States)

^d Catholic University of Daegu   (South Korea)

Author keywords

Glucose; Heart; Hypothermia; Ketoacidosis; Liver; Pyruvate dehydrogenase complex (PDH complex); Pyruvate dehydrogenase kinase (PDHK); Skeletal muscle

Indexed keywords

GLUCOSE; INSULIN; PYRUVATE DEHYDROGENASE KINASE 2; PYRUVATE DEHYDROGENASE KINASE 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; ENZYME ACTIVITY; ENZYME REGULATION; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HYPOGLYCEMIA; HYPOTHERMIA; INSULIN SENSITIVITY; KETOACIDOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY;

ANIMALS; FASTING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYPOTHERMIA; ISOENZYMES; KETOSIS; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES;

EID: 84860161803     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20112197     Document Type: Article

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