Process development and large-scale synthesis of MK-6186, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV

Organic Process Research and Development

Volumn 16, Issue 4, 2012, Pages 605-611

  Goodyear, Adrian ^a   Linghu, Xin ^b   Bishop, Brian ^a   Chen, Cheng ^b   Cleator, Ed ^a   McLaughlin, Mark ^b   Sheen, Faye J ^a   Stewart, Gavin W ^a   Xu, Yingju ^b   Yin , Jingjun ^b  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEPROTECTION; DRUG CANDIDATES; HYDRAZONES; LARGE SCALE SYNTHESIS; N-ALKYLATION; NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS; PROCESS DEVELOPMENT; REGIOCONTROL; SYNTHETIC ROUTES;

ALKYLATION;

EID: 84860145183     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200334x     Document Type: Article

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