Murine collagen antibody induced arthritis (CAIA) and primary mouse hepatocyte culture as models to study cytochrome P450 suppression

Biochemical Pharmacology

Volumn 83, Issue 12, 2012, Pages 1682-1689

  Dickmann, Leslie J ^a   McBride, Helen J ^b   Patel, Sonal K ^a   Miner, Kent ^b   Wienkers, Larry C ^a   Slatter, J Greg ^a  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

Author keywords

Cytochrome P450; Hepatocyte; Inflammation; Interleukin 1 ; Interleukin 6; Tumor necrosis factor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COLLAGEN ANTIBODY; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C29; CYTOCHROME P450 2E1; CYTOCHROME P450 3A11; CYTOCHROME P450 3A13; CYTOCHROME P450 REDUCTASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; SERUM AMYLOID A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; COLLAGEN ANTIBODY INDUCED ARTHRITIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CELL CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENE EXPRESSION; HEPATOCYTES; MICE; MICE, INBRED BALB C;

EID: 84860143501     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.03.001     Document Type: Article

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