Sexually transmissible viral pathogens: Human papillomaviruses and herpes simplex viruses

Nucleic Acid Testing for Human Disease

Volumn , Issue , 2016, Pages 243-273

  Lorincz, Attila T ^a,b,c   Smith, Jennifer S ^d  

^a Digene Corporation   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84859993142     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (205)

1. Lorincz A. Human papillomaviruses, in Lennette EH, Lennette DA, Lennette ET, Eds., Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections, 7th ed. Washington: American Public Health Association, 1995. pp. 465-480.
2. de Villiers E-M, Fauquet C, Broker TR, Bernard H-U, zur Hausen H. Classification of papillomaviruses. Virology 2004; 324 (1): 17-27.
3. Bosch FX, Lorincz A, Munoz N, Meijer CJLM, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002; 55 (4): 244-265.
4. Walboomers JMM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, Snijders PJF, Peto J, Meijer CJLM, Munoz N. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999; 189 (1): 12-19.
5. Lorincz AT, Richart RM. Human papillomavirus DNA testing as an adjunct to cytology in cervical screening programs. Arch Pathol Lab Med 2003; 127 (8): 959-968.
6. Bosch FX, Manos MM, Munoz N, Sherman M, Jansen AM, Peto J, Schiffman MH, Moreno V, Kurman R, Shah KV. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. J Natl Cancer Inst 1995; 87 (11): 796-802.
7. Herrero R, Hildesheim A, Bratti C, Sherman ME, Hutchinson M, Morales J, Balmaceda I, Greenberg MD, Alfaro M, Burk RD, Wacholder S, Plummer M, Schiffman M. Population-based study of human papillomavirus infection and cervical neoplasia in rural Costa Rica. J Natl Cancer Inst 2000; 92 (6): 464-474.
8. Thomas DB, Qin Q, Kuypers J, Kiviat N, Ashley RL, Koetsawang A, Ray RM, Koetsawang S. Human papillomaviruses and cervical cancer in Bangkok. II. Risk factors for in situ and invasive squamous cell cervical carcinomas. Am J Epidemiol 2001; 153 (8): 732-739.
9. Clavel C, Masure M, Bory J-P, Putaud I, Mangeonjean C, Lorenzato F, Nazeyrollas P, Gabriel R, Quereux C, Birembaut P. Human papillomavirus testing in primary screening for the detection of high-grade cervical lesions: a study of 7932 women. Br J Cancer 2001; 84 (12): 1616-1623.
10. Petry K-U, Menton S, Menton M, van Loenen-Frosch F, de Carvalho Gomes H, Holz B, Schopp B, Garbrecht-Buettner S, Davies P, Boehmer G, van den Akker E, Iftner T. Inclusion of HPV testing in routine cervical cancer screening for women above 29 years in Germany: results for 8468 patients. Br J Cancer 2003; 88 (10): 1570-1577.
11. Hildesheim A, Herrero R, Castle PE, Wacholder S, Bratti MC, Sherman ME, Lorincz AT, Burk RD, Morales J, Rodriguez AC, Helgesen K, Alfaro M, Hutchinson M, Balmaceda I, Greenberg M, Schiffman M. HPV co-factors related to the development of cervical cancer: results from a populationbased study in Costa Rica. Br J Cancer 2001; 84 (9): 1219-1226.
12. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55 (2): 74-108.
13. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ. Cancer statistics 2005 CA Cancer J Clin 2005; 55 (1): 10-30.
14. Monsonego J. HPV infections and cervical cancer prevention. Priorities and new directions: highlights of EUROGIN International Expert Meeting, Nice, France, October 21-23, 2004. Gynecol Oncol 2005; 96 (3): 830-839.
15. Fahey MT, Irwig L, Macaskill P. Meta-analysis of Pap test accuracy. Am J Epidemiol 1995; 141 (7): 680-689.
16. Nanda K, McCrory DC, Myers ER, Bastian LA, Hasselblad V, Hickey JD, Matchar DB. Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: a systematic review. Ann Intern Med 2000;132 (10): 810-819.
17. Solomon D, Schiffman M, Tarone B. Comparison of three management strategies for patients with atypical squamous cells of undetermined significance (ASCUS): baseline results from a randomized trial. J Natl Cancer Inst 2001; 93 (4): 293-299.
18. Kulasingam SL, Hughes JP, Kiviat NB, Mao C, Weiss NS, Kuypers JM, Koutsky LA. Evaluation of human papillomavirus testing in primary screening for cervical abnormalities: comparison of sensitivity, specificity, and frequency of referral. JAMA 2002; 288 (14): 1749-1757.
19. Lorincz AT, Reid R, Jenson AB, Greenberg MD, Lancaster W, Kurman RJ. Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types. Obstet Gynecol 1992; 79 (3): 328-337.
20. Schiffman MH, Bauer HM, Hoover RN, Glass AG, Cadell DM, Rush BB, Scott DR, Sherman ME, Kurman RJ, Wacholder S, Stanton CK, Manos MM. Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst 1993; 85 (12): 958-964.
21. Franco EL, Villa LL, Sobrinho JP, Prado JM, Rousseau M-C, Desy M, Rohan TE. Epidemiology of acquisition and clearance of cervical human papillomavirus infection in women from a high-risk area for cervical cancer. J Infect Dis 1999; 180 (5): 1415-1423.
22. Wright TC, Jr., Cox JT, Massad LS, Twiggs LB. 2001 consensus guidelines for the management of women with cervical cytological abnormalities. JAMA 2002; 287 (16): 2120-2129.
23. O'Meara AT. Present standards for cervical cancer screening. Curr Opin Oncol 2002; 14 (5): 505-511.
24. Wright TC, Jr., Schiffman M, Solomon D, Cox JT, Garcia F, Goldie S, Hatch K, Noller KL, Roach N, Runowicz C, Saslow D. Interim guidance for the use of human papillomavirus DNA testing as an adjunct to cervical cytology for screening. Obstet Gynecol 2004; 103 (2): 304-309.
25. Kim JJ, Wright TC, Goldie SJ. Cost-effectiveness of alternative triage strategies for atypical squamous cells of undetermined significance. JAMA 2002; 287 (18): 2382-2390.
26. Goldie SJ, Kim JJ, Wright TC. Cost-effectiveness of human papillomavirus DNA testing for cervical cancer screening in women aged 30 years or more. Obstet Gynecol 2004; 103 (4): 619-631.
27. Mandelblatt J, Lawrence W, Yi B, King J. The balance of harms, benefits, and costs of screening for cervical cancer in older women: the case for continued screening. Arch Intern Med 2004; 164 (3): 245-247; rebuttal: 248.
28. Elfgren K, Rylander E, Radberg T, Strander B, Strand A, Paajanen K, Sjoberg I, Ryd W, Silins I, Dillner J. Colposcopic and histopathologic evaluation of women participating in population-based screening for human papillomavirus deoxyribonucleic acid persistence. Am J Obstet Gynecol 2005; 193 (3, Pt 1): 650-657.
29. Cuzick J, Szarewski A, Cubie H, Hulman G, Kitchener H, Luesley D, McGoogan E, Menon U, Terry G, Edwards R, Brooks C, Desai M, Gie C, Ho L, Jacobs I, Pickles C, Sasieni P. Management of women who test positive for high-risk types of human papillomavirus: the HART study. Lancet 2003; 362 (9399): 1871-1876.
30. Bory J-P, Cucherousset J, Lorenzato M, Gabriel R, Quereux C, Birembaut P, Clavel C. Recurrent human papillomavirus infection detected with the hybrid capture II assay selects women with normal cervical smears at risk for developing high grade cervical lesions: a longitudinal study of 3091 women. Int J Cancer 2002; 102 (5): 519-525.
31. Sherman ME, Lorincz AT, Scott DR, Wacholder S, Castle PE, Glass AG, Mielzynska-Lohnas I, Rush BB, Schiffman M. Baseline cytology, human papillomavirus testing, and risk for cervical neoplasia: a 10-year cohort analysis. J Natl Cancer Inst 2003; 95 (1): 46-52.
32. Dalstein V, Riethmuller D, Pretet J-L, Le Bail Carval K, Sautiere J-L, Carbillet J-P, Kantelip B, Schaal J-P, Mougin C. Persistence and load of high-risk HPV are predictors for development of high-grade cervical lesions: a longitudinal French cohort study. Int J Cancer 2003; 106 (3): 396-403.
33. Kjaer SK, van den Brule AJC, Paull G, Svare EI, Sherman ME, Thomsen BL, Suntum M, Bock JE, Poll PA, Meijer CJLM. Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow-up study. Br Med J 2002; 325 (7364): 572-578.
34. Rozendaal L, Westerga J, van der Linden JC, Walboomers JMM, Voorhorst FJ, Risse EKJ, Boon ME, Meijer CJLM. PCR-based high risk HPV testing is superior to neural network based screening for predicting incident CIN III in women with normal cytology and borderline changes. J Clin Pathol 2000; 53 (8): 606-611.
35. Franceschi S, Clifford GM. Re: A study of the impact of adding HPV types to cervical cancer screening and triage tests. J Natl Cancer Inst 2005; 97 (12): 938-941.
36. Cogliano V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F. Carcinogenicity of human papillomaviruses. Lancet Oncol 2005; 6 (4): 204.
37. Khan MJ, Castle PE, Lorincz AT, Wacholder S, Sherman M, Scott DR, Rush BB, Glass AG, Schiffman M. The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice. J Natl Cancer Inst 2005; 97 (14): 1072-1079.
38. Castle PE, Solomon D, Schiffman M, Wheeler CM, for the ALTS Group. Human papillomavirus type 16 infections and 2-year absolute risk of cervical precancer in women with equivocal or mild cytologic abnormalities. J Natl Cancer Inst 2005; 97 (14): 1066-1071.
39. Munoz N, Bosch FX, de Sanjose S, Herrero R, Castellsague X, Shah KV, Snijders PJF, Meijer CJLM. Epidemiologic classification of human papillomavirus types associated with cervical cancer. New Engl J Med 2003; 348 (6): 518-527.
40. Schiffman M, Khan MJ, Solomon D, Herrero R, Wacholder S, Hildesheim A, Rodriguez AC, Bratti MC, Wheeler CM, Burk RD. Study of the impact of adding HPV types to cervical cancer screening and triage tests. J Natl Cancer Inst 2005; 97 (2): 147-150.
41. Clifford GM, Gallus S, Herrero R, Munoz N, Snijders PJF, Vacarella S, Anh PTH, Ferreccio C, Hieu NT, Matos E, Molano M, Rajkumar R, Ronco G, de Sanjose S, Shin HR, Sukvirach S, Thomas JO, Tunsakul S, Meijer CJLM, Franceschi S. Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: a pooled analysis. Lancet 2005; 366 (9490): 991-998.
42. Cooper K, Herrington CS, Graham AK, Evans MF, McGee JO. In situ evidence for HPV 16, 18, 33 integration in cervical squamous cell cancer in Britain and South Africa. J Clin Pathol 1991; 44 (5): 406-409.
43. Wolber RA, Clement PB. In situ DNA hybridization of cervical small cell carcinoma and adenocarcinoma using biotin-labeled human papillomavirus probes. Mod Pathol 1991; 4 (1): 96-100.
44. Samama B, Plas-Roser S, Schaeffer C, Chateau D, Fabre M, Boehm N. HPV DNA detection by in situ hybridization with catalyzed signal amplification on thin-layer cervical smears. J Histochem Cytochem 2002; 50 (10): 1417-1420.
45. Hesselink AT, van den Brule AJC, Brink AATP, Berkhof J, van Kemenade FJ, Verheijen RHM, Snijders PJF. Comparison of Hybrid Capture 2 with in situ hybridization for the detection of high-risk human papillomavirus in liquid-based cervical samples. Cancer Cytopathol 2004; 102 (1): 11-18.
46. Bewtra C, Xie Q, Soundararajan S, Gatalica Z, Hatcher L. Genital human papillomavirus testing by in situ hybridization in liquid atypical cytologic materials and follow-up biopsies. Acta Cytol 2005; 49 (2): 127-131.
47. Davis-Devine S, Day SJ, Freund GG. Test performance comparison of Inform HPV and Hybrid Capture 2 high-risk HPV DNA tests using the SurePath liquid-based Pap test as the collection method. Am J Clin Pathol 2005; 124 (1): 24-30.
48. Quint WGV, Scholte G, van Doom LJ, Kleter B, Smits PHM, Lindeman J. Comparative analysis of human papillomavirus infections in cervical scrapes and biopsy specimens by general SPF10 PCR and HPV genotyping. J Pathol 2001; 194 (1): 51-58.
49. Coutlee F, Gravitt P, Kornegay J, Hankins C, Richardson H, Lapointe N, Voyer H, Canadian Women's HIV Study Group, Franco E. Use of PGMY primers in L1 consensus PCR improves detection of human papillomavirus DNA in genital samples. J Clin Microbiol 2002; 40 (3): 902-907.
50. Kornegay JR, Shepard AP, Hankins C, Franco E, Lapointe N, Richardson H, Canadian Women's HIV Study Group, Coutlee F. Nonisotopic detection of human papillomavirus DNA in clinical specimens using a consensus PCR and a generic probe mix in an enzyme-linked immunosorbent assay format. J Clin Microbiol 2001; 39 (10): 3530-3536.
51. Schiffman M, Castle PE, Solomon D, Stoler M, Wheeler C. A study of the impact of adding HPV types to cervical cancer screening and triage tests. J Natl Cancer Inst 2005; 97 (12): 939-941. Authors' response to letter by Franceschi, et al.: 938-939.
52. Kulmala S-M, Syrjanen S, Shabalova I, Petrovichev N, Kozachenko V, Podistov J, Ivanchenko O, Zakharenko S, Nerovina R, Kljukina L, Branovskaja M, Grunberga V, Juschenko A, Tosi P, Santopietro R, Syrjanen K. Human papillomavirus testing with the Hybrid Capture 2 assay and PCR as screening tools. J Clin Microbiol 2004; 42 (6): 2470-2475.
53. Massad LS, Schneider MF, Watts DH, Strickler HD, Melnick S, Palefsky J, Anastos K, Levine AM, Minkoff H. HPV testing for triage of HIV-infected women with Papanicolaou smears read as atypical squamous cells of uncertain significance. J Women's Health 2004; 13 (2): 147-153.
54. Sotlar K, Diemer D, Dethleffs A, Hack Y, Stubner A, Vollmer N, Menton S, Menton M, Dietz K, Wallwiener D, Kandolf R, Bultmann B. Detection and typing of human papillomavirus by E6 nested multiplex PCR. J Clin Microbiol 2004; 42 (7): 3176-3184.
55. Chan JK, Monk BJ, Brewer C, Keefe KA, Osann K, McMeekin S, Rose GS, Youssef M, Wilczynski SP, Meyskens FL, Berman ML. HPV infection and number of lifetime sexual partners are strong predictors for 'natural' regression of CIN 2 and 3. Br J Cancer 2003; 89 (6): 1062-1066.
56. Depuydt CE, Vereecken AJ, Salembier GM, Vanbrabant AS, Boels LA, van Herck E, Arbyn M, Segers K, Bogers JJ. Thin-layer liquid-based cervical cytology and PCR for detecting and typing human papillomavirus DNA in Flemish women. Br J Cancer 2003; 88 (4): 560-566.
57. Xi LF, Toure P, Critchlow CW, Hawes SE, Dembele B, Sow PS, Kiviat NB. Prevalence of specific types of human papillomavirus and cervical squamous intraepithelial lesions in consecutive, previously unscreened, West African women over 35 years of age. Int J Cancer 2003; 103 (6): 803-809.
58. Garcia F, Barker B, Santos C, Mendez Brown E, Nuno T, Giuliano A, Davis J. Cross-sectional study of patient-and physician-collected cervical cytology and human papillomavirus. Obstet Gynecol 2003; 102 (2): 266-272.
59. Ferreccio C, Bratti MC, Sherman ME, Herrero R, Wacholder S, Hildesheim A, Burk RD, Hutchinson M, Alfaro M, Greenberg MD, Morales J, Rodriguez AC, Schussler J, Schiffman M. A comparison of single and combined visual, cytologic, and virologic tests as screening strategies in a region at high risk of cervical cancer. Cancer Epidemiol Biomarkers Prev 2003; 12 (9): 815-823.
60. Hughes SA, Sun D, Gibson C, Bellerose B, Rushing L, Chen H, Harlow BL, Genest DR, Sheets EE, Crum CP. Managing atypical squamous cells of undetermined significance (ASCUS): human papillomavirus testing, ASCUS subtyping, or follow-up cytology? Am J Obstet Gynecol 2002; 186 (3): 396-403.
61. Castellsague X, Menendez C, Loscertales M-P, Kornegay JR, dos Santos F, Gomez-Olive FX, Lloveras B, Abarca N, Vaz N, Barreto A, Bosch FX, Alonso P. Human papillomavirus genotypes in rural Mozambique. Lancet 2001; 359 (9291): 1429-1430.
62. Schneider A, Hoyer H, Lotz B, Leistritz S, Kuhne-Heid R, Nindl I, Muller B, Haerting J, Durst M. Screening for high-grade cervical intra-epithelial neoplasia and cancer by testing for high-risk HPV, routine cytology or colposcopy. Int J Cancer 2000; 89 (6): 529-534.
63. Adam E, Berkova Z, Daxnerova Z, Icenogle J, Reeves WC, Kaufman RH. Papillomavirus detection: demographic and behavioral characteristics influencing the identification of cervical disease. Am J Obstet Gynecol 2000; 182 (2): 257-264.
64. Cuzick J, Beverley E, Ho L, Terry G, Sapper H, Mielzynska I, Lorincz A, Chan W-K, Krausz T, Soutter P. HPV testing in primary screening of older women. Br J Cancer 1999; 81 (3): 554-558.
65. Qu W, Jiang G, Cruz Y, Chang CJ, Ho GYF, Klein RS, Burk RD. PCR detection of human papillomavirus: comparison between MY09/MY11 and GP5+/GP6+ primer systems. J Clin Microbiol 1997; 35 (6): 1304-1310.
66. Karlsen F, Kalantari M, Jenkins A, Pettersen E, Kristensen G, Holm R, Johansson B, Hagmar B. Use of multiple PCR primer sets for optimal detection of human papillomavirus. J Clin Microbiol 1996; 34 (9): 2095-2100.
67. Lorincz AT. Hybrid Capture™ method for detection of human papillomavirus DNA in clinical specimens: a tool for clinical management of equivocal Pap smears and for population screening. J Obstet Gynaecol Res 1996; 22 (6): 629-636.
68. Lorincz A, Anthony J. Advances in HPV detection by Hybrid Capture®. Pap Rep 2001; 12 (6): 145-154.
69. Salmeron J, Lazcano-Ponce E, Lorincz A, Hernandez M, Hernandez P, Leyva A, Uribe M, Manzanares H, Antunez A, Carmona E, Ronnett BM, Sherman ME, Bishai D, Ferris D, Flores Y, Yunes E, Shah KV. Comparison of HPV-based assays with Papanicolaou smears for cervical cancer screening in Morelos State, Mexico. Cancer Causes Control 2003; 14 (6): 505-512.
70. Belinson JL, Qiao YL, Pretorius RG, Zhang WH, Rong SD, Huang MN, Zhao FH, Wu LY, Ren SD, Huang RD, Washington MF, Pan QJ, Li L, Fife D. Shanxi Province cervical cancer screening study II: self-sampling for high-risk human papillomavirus compared to direct sampling for human papillomavirus and liquid based cervical cytology. Int J Gynecol Cancer 2003; 13 (6): 819-826.
71. Belinson J, Qiao YL, Pretorius R, Zhang WH, Elson P, Li L, Pan QJ, Fischer C, Lorincz A, Zahniser D. Shanxi Province cervical cancer screening study: a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia. Gynecol Oncol 2001; 83 (2): 439-444.
72. Wright TC, Jr., Denny L, Kuhn L, Pollack A, Lorincz A. HPV DNA testing of self-collected vaginal samples compared with cytologic screening to detect cervical cancer. JAMA 2000; 283 (1): 81-86.
73. Schiffman M, Herrero R, Hildesheim A, Sherman ME, Bratti M, Wacholder S, Alfaro M, Hutchinson M, Morales J, Greenberg MD, Lorincz AT. HPV DNA testing in cervical cancer screening: results from women in a high-risk province of Costa Rica. JAMA 2000; 283 (1): 87-93.
74. Ratnam S, Franco EL, Ferenczy A. Human papillomavirus testing for primary screening of cervical cancer precursors. Cancer Epidemiol Biomarkers Prev 2000; 9 (9): 945-951.
75. Carozzi FM, Del Mistro A, Confortini M, Sani C, Puliti D, Trevisan R, De Marco L, Tos AG, Girlando S, Dalla Palma P, Pellegrini A, Schiboni ML, Crucitti P, Pierotti P, Vignato A, Ronco G. Reproducibility of HPV DNA testing by Hybrid Capture 2 in a screening setting: intralaboratory and interlaboratory quality control in seven laboratories participating in the same clinical trial. Am J Clin Pathol 2005; 124 (5): 1-6.
76. Cubie HA, Moore C, Waller M, Moss S. Development of a quality assurance programme for HPV testing with the UK NHS cervical screening LBC/HPV studies. J Clin Virol 2005; 33 (4): 287-292.
77. Peyton CL, Schiffman M, Lorincz AT, Hunt WC, Mielzynska I, Bratti C, Eaton S, Hildesheim A, Morera LA, Rodriguez AC, Sherman ME, Wheeler CM. Comparison of PCR-and Hybrid Capturebased HPV detection systems using multiple cervical specimen collection strategies. J Clin Microbiol 1998; 36 (11): 3248-3254.
78. Erratum: 1999; 37 (2): 478.
79. Terry G, Ho L, Londesborough P, Cuzick J, Mielzynska-Lohnas I, Lorincz A. Detection of high-risk HPV types by the Hybrid Capture 2 test. J Med Virol 2001; 65 (1): 155-162.
80. Snijders PJF, van den Brule AJC, Meijer CJLM. The clinical relevance of human papillomavirus testing: relationship between analytical and clinical sensitivity. J Pathol 2003; 201 (1): 1-6.
81. Arbyn M, Buntinx F, Van Ranst M, Paraskevaidis E, Martin-Hirsch P, Dillner J. Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect highgrade intraepithelial neoplasia. J Natl Cancer Inst 2004; 96 (4): 280-293.
82. Paraskevaidis E, Arbyn M, Sotiriadis A, Diakomanolis E, Martin-Hirsch P, Koliopoulos G, Markydimas G, Tofoski J, Roukos DH. The role of HPV DNA testing in the follow-up period after treatment for CIN: a systematic review of the literature. Cancer Treat Rev 2004; 30 (2): 205-211.
83. Clavel C, Masure M, Bory J-P, Putaud I, Mangeonjean C, Lorenzato M, Gabriel R, Quereux C, Birembaut P. Hybrid Capture II-based human papillomavirus detection, a sensitive test to detect in routine high-grade cervical lesions: a preliminary study on 1518 women. Br J Cancer 1999; 80 (9): 1306-1311.
84. Bulkmans NWJ, Rozendaal L, Voorhorst FJ, Snijders PJF, Meijer CJLM. Long-term protective effect of high-risk human papillomavirus testing in population-based cervical screening. Br J Cancer 2005; 92 (9): 1800-1802.
85. Bigras G, de Marval F. The probability for a Pap test to be abnormal is directly proportional to HPV viral load: results from a Swiss study comparing HPV testing and liquid-based cytology to detect cervical cancer precursors in 12,842 women. Br J Cancer 2005; 93 (5): 575-581.
86. Nieminen P, Vuorma S, Viikki M, Hakama M, Anttila A. Comparison of HPV test versus conventional and automation-assisted Pap screening as potential screening tools for preventing cervical cancer. BJOG 2004; 111 (8): 842-848.
87. Kuhn L, Denny L, Pollack A, Lorincz A, Richart RM, Wright TC. Human papillomavirus DNA testing for cervical cancer screening in low-resource settings. J Natl Cancer Inst 2000; 92 (10): 818-825.
88. Fetterman B, Shaber R, Pawlick G, Kinney W. 2005. Lessons from practice: the first hundred thousand Pap and HPV cotests for general population screening. Abstr C-02. Poster presented at 22nd International Papillomavirus Conference, Vancouver, April 30-May 6, 2005.
89. Mandelblatt JS, Lawrence WF, Womack SM, Jacobson D, Yi B, Hwang Y, Gold K, Barter J, Shah K. Benefits and costs of using HPV testing to screen for cervical cancer. JAMA 2002; 287 (18): 2372-2381.
90. Hill AB. The environment and disease: association or causation? President's address. Proc Royal Soc Med 1965; 58: 295-300.
91. Saslow D, Runowicz CD, Solomon D, Moscicki A-B, Smith RA, Eyre HJ, Cohen C. American Cancer Society guidelines for the early detection of cervical neoplasia and cancer. CA Cancer J Clin 2002; 52 (6): 342-362.
92. Erratum in 2003; 53 (2): 126-127.
93. ACOG. Clinical management guidelines for obstetrician-gynecologists: cervical cytology screening. Obstet Gynecol 2003; 102 (2): 417-427. Practice Bulletin Number 45, August 2003; replaces Committee Opinion 152, March 1995.
94. ACOG. Clinical management guidelines for obstetrician-gynecologists: human papillomavirus. Obstet Gynecol 2005; 105 (4): 905-918. ACOG Practice Bulletin 61, April 2005.
95. ACOG. Clinical management guidelines for obstetrician-gynecologists: management of abnormal cervical cytology and histology. Obstet Gynecol 2005; 106 (3): 645-664. ACOG Practice Bulletin 66, September 2005.
96. Corey L, Wald A. Genital herpes, in Holmes KK, Mardh P-A, Sparling PF, Lemon SM, Stamm WE, Piot P, Wasserheit JN, Eds., Sexually Transmitted Diseases. 3rd ed., New York: McGraw-Hill, 1999. pp. 285-312.
97. Nahmias AJ, Lee FK, Beckman-Nahmias S. Sero-epidemiological and -sociological patterns of herpes simplex virus infection in the world. Scand J Infect Dis Suppl 1990; 69: 19-36.
98. Smith JS, Robinson NJ. Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review. J Infect Dis 2002; 186 (Suppl 1): S3-S28.
99. Wald A, Corey L, Cone R, Hobson A, Davis G, Zeh J. Frequent genital herpes simplex virus 2 shedding in immunocompetent women: effect of acyclovir treatment. J Clin Invest 1997; 99 (5): 1092-1097.
100. Brugha R, Keersmaekers K, Renton A, Meheus A. Genital herpes infection: a review. Int J Epidemiol 1997; 26 (4): 698-709.
101. Tran T, Druce JD, Catton MC, Kelly H, Birch CJ. Changing epidemiology of genital herpes simplex virus infection in Melbourne, Australia, between 1980 and 2003. Sex Transm Infect 2004; 80 (4): 277-279.
102. Dolan A, Jamieson FE, Cunningham C, Barnett BC, McGeoch DJ. The genome sequence of herpes simplex virus type 2. J Virol 1998; 72 (3): 2010-2021.
103. Mertz GJ, Coombs RW, Ashley R, Jourden J, Remington M, Winter C, Fahnlander A, Guinan M, Ducey H, Corey L. Transmission of genital herpes in couples with one symptomatic and one asymptomatic partner: a prospective study. J Infect Dis 1998; 157 (6): 1169-1177.
104. Koelle DM, Wald A. Herpes simplex virus: the importance of asymptomatic shedding. J Antimicrob Chemother 2000; 45: 1-8.
105. Benedetti JK, Zeh J, Corey L. Clinical reactivation of genital herpes simplex virus infection decreases in frequency over time. Ann Intern Med 1999; 131 (1): 14-20.
106. Wald A, Zeh J, Selke S, Ashley RL, Corey L. Virologic characteristics of subclinical and symptomatic genital herpes infections. New Engl J Med 1995; 333 (12): 770-775.
107. Wald A, Zeh J, Selke S, Warren T, Ashley R, Corey L. Genital shedding of herpes simplex virus among men. J Infect Dis 2002; 186: S34-S39.
108. Corey L, Handsfield HH. Genital herpes and public health: addressing a global problem. JAMA 2000; 283 (6): 791-794.
109. Cusini M, Ghislanzoni M. The importance of diagnosing genital herpes. J Antimicrob Chemother 2001; 47: 9-16.
110. Whitley R, Arvin A, Prober C, Corey L, Burchett S, Plotkin S, Starr S, Jacobs R, Powell D, Nahmias A, Sumaya C, Edwards K, Alford C, Caddell G, Soong S-J. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. New Engl J Med 1991; 324 (7): 450-457.
111. Brown ZA, Benedetti J, Selke S, Ashley R, Watts DH, Corey L. Asymptomatic maternal shedding of herpes simplex virus at the onset of labor: relationship to preterm labor. Obstet Gynecol 1996; 87 (4): 483-488.
112. Brown ZA, Selke S, Zeh J, Kopelman J, Maslow A, Ashley RL, Watts H, Berry S, Herd M, Corey L. The acquisition of herpes simplex virus during pregnancy. New Engl J Med 1997; 337 (8): 509-515.
113. Gutierrez KM, Falkovitz Halpern MS, Maldonado Y, Arvin AM. The epidemiology of neonatal herpes simplex virus infections in California from 1985 to 1995. J Infect Dis 1999; 180 (1): 199-202.
114. Whitley R. Neonatal herpes simplex virus infection. Curr Opin Infect Dis 2004; 17 (3): 243-246.
115. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV-2 transmission. Antiviral Res 2004; 63: S27-S35.
116. Keet IPM, Lee FK, van Griensven GJP, Lange JMA, Nahmias A, Coutinho RA. Herpes simplex virus type 2 and other genital ulcerative infections as a risk factor for HIV-1 acquisition. Genitourin Med 1990; 66 (5): 330-333.
117. Wald A, Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 1-seropositive persons: a meta-analysis. J Infect Dis 2002; 185 (1): 45-52.
118. Augenbraun M, Feldman J, Chirgwin K, Zenilman J, Clarke L, DeHovitz J, Landesman S, Minkoff H. Increased genital shedding of herpes simplex virus type 2 in HIV-seropositive women. Ann Intern Med 1995; 123 (11): 845-847.
119. Mostad SB, Kreiss JK, Ryncarz A, Chohan B, Mandaliya K, Ndinya-Achola J, Bwayo JJ, Corey L. Cervical shedding of herpes simplex virus and cytomegalovirus throughout the menstrual cycle in women infected with human immunodeficiency virus type 1. Am J Obstet Gynecol 2000; 183 (4): 948-955.
120. Lowhagen GB, Bergbrant IM, Bergstrom T, Ryd W, Voog E. PCR detection of Epstein-Barr virus, herpes simplex virus and human papillomavirus from the anal mucosa in HIV-seropositive and HIVseronegative homosexual men. Int J STD AIDS 1999; 10 (9): 615-618.
121. Posavad CM, Wald A, Kuntz S, Huang ML, Selke S, Krantz E, Corey L. Frequent reactivation of herpes simplex virus among HIV-1-infected patients treated with highly active antiretroviral therapy. J Infect Dis 2004; 190 (4): 693-696.
122. Schacker T. The role of HSV in the transmission and progression of HIV. Herpes 2001; 8 (2): 46-49.
123. Wald A, Corey L. How does herpes simplex virus type 2 influence human immunodeficiency virus infection and pathogenesis? J Infect Dis 2003; 187 (10): 1509-1512.
124. Ashley RL. Laboratory techniques in the diagnosis of herpes simplex infection. Genitourin Med 1993; 69 (3): 174-183.
125. Aurelian L. Herpes simplex viruses, in Specter S, Lancz G, Eds., Clinical Virology Manual, 2nd ed., Amsterdam: Elsevier; 1992. pp. 473-499.
126. Cohen PR. Tests for detecting herpes simplex virus and varicella-zoster virus infections. Dermatol Clin 1994; 12 (1): 51-68.
127. Koutsky LA, Stevens CE, Holmes KK, Ashley RL, Kiviat NB, Critchlow CW, Corey L. Underdiagnosis of genital herpes by current clinical and viral isolation procedures. New Engl J Med 1992; 326 (23): 1533-1539.
128. Warford AL, Levy RA, Rekrut KA. Evaluation of a commercial enzyme-linked immunosorbent assay for detection of herpes simplex virus antigen. J Clin Microbiol 1984; 20 (3): 490-493.
129. Lafferty WE, Krofft S, Remington M, Giddings R, Winter C, Cent A, Corey L. Diagnosis of herpes simplex virus by direct immunofluorescence and viral isolation from samples of external genital lesions in a high-prevalence population. J Clin Microbiol 1987; 25 (2): 323-326.
130. Redfield DC, Richman DD, Albanil S, Oxman MN, Wahl GM. Detection of herpes simplex virus in clinical specimens by DNA hybridization. Diagn Microbiol Infect Dis 1983; 1 (2): 117-128.
131. Cullen AP, Long CD, Lorincz AT. Rapid detection and typing of herpes simplex virus DNA in clinical specimens by the Hybrid Capture II signal amplification probe test. J Clin Microbiol 1997; 35 (9): 2275-2278.
132. Ashley RL. Performance and use of HSV type-specific serology test kits. Herpes 2002; 9 (2): 38-45.
133. Cleary KL, Pare E, Stamilio D, Macones GA. Type-specific screening for asymptomatic herpes infection in pregnancy: a decision analysis. BJOG 2005; 112 (6): 731-736.
134. Sauerbrei A, Wutzler P. Laboratory diagnosis of central nervous system infections caused by herpes viruses. J Clin Virol 2002; 25: S45-S51.
135. Kimura H, Futamura M, Kito H, Ando T, Goto M, Kuzushima K, Shibata M, Morishima T. Detection of viral DNA in neonatal herpes simplex virus infections: frequent and prolonged presence in serum and cerebrospinal fluid. J Infect Dis 1991; 164 (2): 289-293.
136. Rowley AH, Whitley RJ, Lakeman FD, Wolinsky SM. Rapid detection of herpes simplex virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet 1990; 335 (8687): 440-441.
137. Baringer JR, Pisani P. Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 1994; 36 (6): 823-829.
138. Malm G, Forsgren M. Neonatal herpes simplex virus infections: HSV DNA in cerebrospinal fluid and serum. Arch Dis Child Fetal Neonatal Ed 1999; 81 (1): F24-F29.
139. Openshaw H, McNeill JI, Lin XH, Niland J, Cantin EM. Herpes simplex virus DNA in normal corneas: persistence without viral shedding from ganglia. J Med Virol 1995; 46 (1): 75-80.
140. Miura S, Smith CC, Burnett JW, Aurelian L. Detection of viral DNA within skin of healed recurrent herpes simplex infection and erythema multiforme lesions. J Invest Dermatol 1992; 98 (1): 68-72.
141. Wald A, Matson P, Ryncarz A, Corey L. Detection of herpes simplex virus DNA in semen of men with genital HSV-2 infection. Sex Transm Dis 1999; 26 (1): 1-3.
142. Robinson PA, High AS, Hume WJ. Rapid detection of human herpes simplex virus type 1 in saliva. Arch Oral Biol 1992; 37 (10): 797-806.
143. Waldhuber MG, Denham I, Wadey C, Leong-Shaw W, Cross GF. Detection of herpes simplex virus in genital specimens by type-specific polymerase chain reaction. Int J STD AIDS 1999; 10 (2): 89-92.
144. Wald A, Huang M-L, Carrell D, Selke S, Corey L. Polymerase chain reaction for detection of herpes simplex virus (HSV) DNA on mucosal surfaces: comparison with HSV isolation in cell culture. J Infect Dis 2003; 188 (9): 1345-1351.
145. Cone RW, Hobson AC, Brown Z, Ashley R, Berry S, Winter C, Corey L. Frequent detection of genital herpes simplex virus DNA by polymerase chain reaction among pregnant women. JAMA 1994; 272 (10): 792-796.
146. Hardy DA, Arvin AM, Yasukawa LL, Bronzan RN, Lewinshohn DM, Hensleigh PA, Prober CG. Use of polymerase chain reaction for successful identification of asymptomatic genital infection with herpes simplex virus in pregnant women at delivery. J Infect Dis 1990; 162 (5): 1031-1035.
147. Cone RW, Hobson AC, Palmer J, Remington M, Corey L. Extended duration of herpes simplex virus DNA in genital lesions detected by the polymerase chain reaction. J Infect Dis 1991; 164 (4): 757-760.
148. Kinghorn GR. Genital herpes: natural history and treatment of acute episodes. J Med Virol 1993; Suppl. 1: 33-38.
149. Jerome KR, Huang M-L, Wald A, Selke S, Corey L. Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR. J Clin Microbiol 2002; 40 (7): 2609-2611.
150. Kessler HH, Muhlbauer G, Rinner B, Stelzl E, Berger A, Dorr H-W, Santner B, Marth E, Rabenau H. Detection of herpes simplex virus DNA by real-time PCR. J Clin Microbiol 2000; 38 (7): 2638-2642.
151. Adelson ME, Feola M, Trama J, Tilton RC, Mordechai E. Simultaneous detection of herpes simplex virus types 1 and 2 by real-time PCR and pyrosequencing. J Clin Virol 2005; 33 (1): 25-34.
152. Corey L, Huang M-L, Selke S, Wald A. Differentiation of herpes simplex virus types 1 and 2 in clinical samples by a real-time Taqman PCR assay. J Med Virol 2005; 76 (3): 350-355.
153. Lafferty WE, Coombs RW, Benedetti J, Critchlow C, Corey L. Recurrences after oral and genital herpes simplex virus infection: influence of site of infection and viral type. New Engl J Med 1987; 316 (23): 1444-1449.
154. Kimberlin DW, Whitley RJ. Neonatal herpes: what have we learned. Semin Pediatr Infect Dis 2005; 16 (1): 7-16.
155. Weinberg A, Canto CLM, Pannuti CS, Kwang WN, Garcia SAL, Zugaib M. Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in Sao Paulo, Brazil. Rev Inst Med Trop Sao Paulo 1993; 35 (3): 285-290.
156. Stagno S, Whitley RJ. Herpesvirus infections in neonates and children: cytomegalovirus and herpes simplex virus, in Holmes KK, Mardh P-A, Sparling PF, Lemon SM, Stamm WE, Piot P, Wasserheit JN, Eds., Sexually Transmitted Diseases, 3rd ed., New York: McGraw-Hill; 1999. pp. 1191-1212.
157. Koelle DM, Benedetti J, Langenberg A. Asymptomatic reactivation of herpes simplex virus in women after the first episode of genital herpes. Ann Intern Med 1992; 116 (6): 433-437.
158. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Introduction: is viral shedding a surrogate marker for transmission of genital herpes? Antiviral Res 2004; 63: S3-S10.
159. Barton SE, Munday PE, Patel RJ. Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management. Int J STD AIDS 1996; 7 (4): 229-232.
160. Stanberry LR. Asymptomatic herpes simplex virus shedding and Russian roulette. Clin Infect Dis 2000; 30 (2): 268-269.
161. Atkins JT. HSV PCR for CNS infections: pearls and pitfalls. Pediatr Infect Dis J 1999; 18 (9): 823-824.
162. Burggraf S, Olgemoller B. Simple technique for internal control of real-time amplification assays. Clin Chem 2004; 50 (5): 819-825.
163. Kok T, Wati S, Bayly B, Devonshire-Gill D, Higgins G. Comparison of six nucleic acid extraction methods for detection of viral DNA or RNA sequences in four different non-serum specimen types. J Clin Virol 2000; 16 (2): 59-63.
164. Issa NC, Espy MJ, Uhl JR, Harmsen WS, Mandrekar JN, Gullerud RE, Davis MD, Smith TF. Comparison of specimen processing and nucleic acid extraction by the swab extraction tube system versus the MagNA Pure LC system for laboratory diagnosis of herpes simplex virus infections by LightCycler PCR. J Clin Microbiol 2005; 43 (3): 1059-1063.
165. Vesanen M, Piiparinen H, Kallio A, Vaheri A. Detection of herpes simplex virus DNA in cerebrospinal fluid samples using the polymerase chain reaction and microplate hybridization. J Virol Methods 1996; 59 (1-2): 1-11.
166. Boriskin YS, Rice PS, Stabler RA, Hinds J, Al Ghusein H, Vass K, Butcher PD. DNA microarrays for virus detection in cases of central nervous system infection. J Clin Microbiol 2004; 42 (12): 5811-5818.
167. Diaz-Mitoma F, Ruben M, Sacks S, MacPherson P, Caissie G. Detection of viral DNA to evaluate outcome of antiviral treatment of patients with recurrent genital herpes. J Clin Microbiol 1996; 34 (3): 657-663.
168. Guibinga GH, Coutlee F, Kessous A, Hankins C, Lapointe N, Richer G, Tousignant J. Detection of a transforming fragment of herpes simplex virus type 2 in clinical specimens by PCR. J Clin Microbiol 1996; 34 (7): 1654-1659.
169. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV shedding. Antiviral Res 2004; 63: S19-S26.
170. Kinghorn GR. Limiting the spread of genital herpes. Scand J Infect Dis 1996; 100: 20-25.
171. Bacon TH, Levin MJ, Leary JJ, Sarisky RT, Sutton D. Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy. Clin Microbiol Rev 2003; 16 (1): 114-128.
172. Corey L, Ashley R. Prevention of herpes simplex virus type 2 transmission with antiviral therapy. Herpes 2004; 11:170A-174A.
173. Corey L, Wald A, Patel R, Sacks SL, Tyring SK, Warren T, Douglas JM, Jr., Paavonen J, Morrow RA, Beutner KR, Stratchounsky LS, Mertz G, Keene ON, Watson HA, Tait D, Vargas-Cortes M. Once-daily valacyclovir to reduce the risk of transmission of genital herpes. New Engl J Med 2004; 350 (1): 11-20.
174. Stingley SW, Garcia Ramirez JJ, Aguilar SA, Simmen K, Sandri-Goldin RM, Ghazal P, Wagner EK. Global analysis of herpes simplex virus type 1 transcription using an oligonucleotide-based DNA microarray. J Virol 2000; 74 (21): 9916-9927.
175. Tenorio A, Echevarria JE, Casas I, Echevarria JM, Tabares E. Detection and typing of human herpesviruses by multiplex polymerase chain reaction. J Virol Methods 1993; 44 (2-3): 261-269.
176. Markoulatos P, Georgopoulou A, Kotsovassilis C, Karabogia-Karaphillides P, Spyrou N. Detection and typing of HSV-1, HSV-2, and VZV by a multiplex polymerase chain reaction. J Clin Lab Anal 2000; 14 (5): 214-219.
177. Mitrani-Rosenbaum S, Tsvieli R, Lavie O, Boldes R, Anteby E, Shimonovitch S, Lazarovitch T, Friedmann A. Simultaneous detection of three common sexually transmitted agents by polymerase chain reaction. Am J Obstet Gynecol 1994;1994 (3): 784-790.
178. Koutsky LA, Ault KA, Wheeler CM, Brown DR, Barr E, Alvarez FB, Chiacchierini LM, Jansen KU. A controlled trial of a human papillomavirus type 16 vaccine. New Engl J Med 2002; 347 (21): 1645-1651.
179. Harper DM, Franco EL, Wheeler C, Ferris DG, Jenkins D, Schuind A, Zahaf T, Innis B, Naud P, De Carvalho NS, Roteli-Martins CM, Teixeira J, Blatter MM, Korn AP, Quint W, Dubin G. Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial. Lancet 2004; 364 (9447): 1757-1765.
180. Stanberry LR, Spruance SL, Cunningham AL, Bernstein DI, Mindel A, Sacks S, Tyring S, Aoki FY, Slaoui M, Denis M, Vandepapeliere P, Dubin G. Glycoprotein-D adjuvant vaccine to prevent genital herpes. New Engl J Med 2002; 347 (21): 1652-1661.
181. Flores Y, Bishai D, Lazcano E, Shah K, Lorincz A, Hernandez M, Salmeron J. Improving cervical cancer screening in Mexico: results from the Morelos HPV study. Salud Publica Mex 2003; 45: S388-S398.
182. Kimura H, Shibata M, Kuzushima K, Nishikawa K, Nishiyama Y, Morishima T. Detection and direct typing of herpes simplex virus by polymerase chain reaction. Med Microbiol Immunol (Berl) 1990; 179 (4): 177-184.
183. Rogers BB, Josephson SL, Mak SK, Sweeney PJ. Polymerase chain reaction amplification of herpes simplex virus DNA from clinical samples. Obstet Gynecol 1992; 79 (3): 464-469.
184. Cone RW, Swenson PD, Hobson AC, Remington M, Corey L. Herpes simplex virus detection from genital lesions: a comparative study using antigen detection (HerpChek) and culture. J Clin Microbiol 1993; 31 (7): 1774-1776.
185. Orle KA, Gates CA, Martin DH, Body BA, Weiss JB. Simultaneous PCR detection of Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus types 1 and 2 from genital ulcers. J Clin Microbiol 1996; 34 (1): 49-54.
186. Boggess KA, Watts DH, Hobson AC, Ashley RL, Brown ZA, Corey L. Herpes simplex virus type 2 detection by culture and polymerase chain reaction and relationship to genital symptoms and cervical antibody status during the third trimester of pregnancy. Am J Obstet Gynecol 1997; 176 (2): 443-451.
187. Morse SA, Trees DL, Htun Y, Radebe F, Orle KA, Dangor Y, Beck-Sague CM, Schmid S, Fehler G, Weiss JB, Ballard RC. Comparison of clinical diagnosis and standard laboratory and molecular methods for the diagnosis of genital ulcer disease in Lesotho: association with human immunodeficiency virus infection. J Infect Dis 1997; 175 (3): 583-589.
188. Safrin S, Shaw H, Bolan G, Cuan J, Chiang CS. Comparison of virus culture and the polymerase chain reaction for diagnosis of mucocutaneous herpes simplex virus infection. Sex Transm Dis 1997; 24 (3): 176-180.
189. Slomka MJ, Emery L, Munday PE, Moulsdale M, Brown DWG. A comparison of PCR with virus isolation and direct antigen detection for diagnosis and typing of genital herpes. J Med Virol 1998; 55 (2): 177-183.
190. do Nascimento MC, Sumita LM, de Souza VA, Pannuti CS. Detection and direct typing of herpes simplex virus in perianal ulcers of patients with AIDS by PCR. J Clin Microbiol 1998; 36 (3): 848-849.
191. Beards G, Graham C, Pillay D. Investigation of vesicular rashes for HSV and VZV by PCR. J Med Virol 1998; 54 (3): 155-157.
192. Coyle PV, Desai A, Wyatt D, McCaughey C, O'Neill HJ. A comparison of virus isolation, indirect immunofluorescence and nested multiplex polymerase chain reaction for the diagnosis of primary and recurrent herpes simplex type 1 and type 2 infections. J Virol Methods 1999; 83 (1-2): 75-82.
193. Madhavan HN, Priya K, Anand AR, Therese KL. Detection of herpes simplex virus (HSV) genome using polymerase chain reaction (PCR) in clinical samples: comparison of PCR with standard laboratory methods for the detection of HSV. J Clin Virol 1999; 14 (2): 145-151.
194. Ryncarz AJ, Goddard J, Wald A, Huang M-L, Roizman B, Corey L. Development of a high-throughput quantitative assay for detecting herpes simplex virus DNA in clinical samples. J Clin Microbiol 1999; 37 (6): 1941-1947.
195. Espy MJ, Ross TK, Teo R, Svien KA, Wold AD, Uhl JR, Smith TF. Evaluation of LightCycler PCR for implementation of laboratory diagnosis of herpes simplex virus infections. J Clin Microbiol 2000; 38 (8): 3116-3118.
196. Espy MJ, Uhl JR, Mitchell PS, Thorvilson JN, Svien KA, Wold AD, Smith TF. Diagnosis of herpes simplex virus infections in the clinical laboratory by LightCycler PCR. J Clin Microbiol 2000; 38 (2): 795-799.
197. Bruisten SM, Cairo I, Fennema H, Pijl A, Buimer M, Peerbooms PGH, Van Dyck E, Meijer A, Ossewaarde JM, van Doornum GJJ. Diagnosing genital ulcer disease in a clinic for sexually transmitted diseases in Amsterdam, The Netherlands. J Clin Microbiol 2001; 39 (2): 601-605.
198. Marshall DS, Linfert DR, Draghi A, McCarter YS, Tsongalis GJ. Identification of herpes simplex virus genital infection: comparison of a multiplex PCR assay and traditional viral isolation techniques. Mod Pathol 2001; 14 (3): 152-156.
199. Espy MJ, Rys PN, Wold AD, Uhl JR, Sloan LM, Jenkins GD, Ilstrup DM, Cockerill FR, III, Patel R, Rosenblatt JE, Smith TF. Detection of herpes simplex virus DNA in genital and dermal specimens by LightCycler PCR after extraction using the IsoQuick, MagNA Pure, and BioRobot 9604 methods. J Clin Microbiol 2001; 39 (6): 2233-2236.
200. Burrows J, Nitsche A, Bayly B, Walker E, Higgins G, Kok T. Detection and subtyping of Herpes simplex virus in clinical samples by LightCycler PCR, enzyme immunoassay and cell culture. BMC Microbiology 2002; 2 (1): 12.
201. Druce J, Catton M, Chibo D, Minerds K, Tyssen D, Kostecki R, Maskill B, Leong-Shaw W, Gerrard M, Birch C. Utility of a multiplex PCR assay for detecting herpes virus DNA in clinical samples. J Clin Microbiol 2002; 40 (5): 1728-1732.
202. Scoular A, Gillespie G, Carman WF. Polymerase chain reaction for diagnosis of genital herpes in a genitourinary medicine clinic. Sex Transm Infect 2002; 78 (1): 21-25.
203. van Doornum GJJ, Guldemeester J, Osterhaus ADME, Niesters HGM. Diagnosing herpes virus infections by real-time amplification and rapid culture. J Clin Microbiol 2003; 41 (2): 576-580.
204. Mengelle C, Sandres-Saune K, Miedouge M, Mansuy J-M, Bouquies C, Isopet J. Use of two realtime polymerase chain reactions (PCRs) to detect herpes simplex type 1 and 2-DNA after automated extraction of nucleic acid. J Med Virol 2004; 74 (3): 459-462.
205. Ramaswamy M, McDonald C, Smith M, Thomas D, Maxwell S, Tenant-Flowers M, Geretti AM. Diagnosis of genital herpes by real time PCR in routine clinical practice. Sex Transm Infect 2004; 80 (5): 406-410.