In silico design, synthesis & pharmacological screening of some quinazolinones as possible GABAA receptor agonists for anticonvulsant activity

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue 2, 2012, Pages 466-469

  Chikhale, Hemant ^a   Lade, Kedar ^a   Joshi, Poorvashree ^a   Kudale, Sneha ^a   Nerkar, Amit ^a   Sawant, Sanjay ^a  

^a STES's Smt Kashibai Navale College of Pharmacy   (India)

Author keywords

Anticonvulsant activity; Biological activity prediction; GABA A receptors; In silico; Quinazolinones

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ANTICONVULSIVE AGENT; DIAZEPAM; ISONIAZID; PLASMA PROTEIN; QUINAZOLINONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BLOOD BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; COMPUTER MODEL; COMPUTER PROGRAM; CONTROLLED STUDY; CONVULSION; DRUG ABSORPTION; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PREDICTION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTITATIVE STRUCTURE BIOLOGICAL ACTIVITY RELATION; SCORING SYSTEM; THIN LAYER CHROMATOGRAPHY;

EID: 84859974609     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

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