-
1
-
-
9144220789
-
Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial
-
Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, et al. (2004) Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA 291: 187-194.
-
(2004)
JAMA
, vol.291
, pp. 187-194
-
-
Wong, B.C.1
Lam, S.K.2
Wong, W.M.3
Chen, J.S.4
Zheng, T.T.5
-
2
-
-
58149393680
-
Exploring the cost-effectiveness of Helicobacter pylori screening to prevent gastric cancer in China in anticipation of clinical trial results
-
Yeh JM, Kuntz KM, Ezzati M, Goldie SJ, (2009) Exploring the cost-effectiveness of Helicobacter pylori screening to prevent gastric cancer in China in anticipation of clinical trial results. Int J Cancer 124: 157-166.
-
(2009)
Int J Cancer
, vol.124
, pp. 157-166
-
-
Yeh, J.M.1
Kuntz, K.M.2
Ezzati, M.3
Goldie, S.J.4
-
3
-
-
30344457320
-
Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis
-
Hatakeyama M, Higashi H, (2005) Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis. Cancer Sci 96: 835-843.
-
(2005)
Cancer Sci
, vol.96
, pp. 835-843
-
-
Hatakeyama, M.1
Higashi, H.2
-
4
-
-
14544295698
-
Characterization of CagA variable region of Helicobacter pylori isolates from Chinese patients
-
Zhu YL, Zheng S, Du Q, Qian KD, Fang PC, (2005) Characterization of CagA variable region of Helicobacter pylori isolates from Chinese patients. World J Gastroenterol 11: 880-884.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 880-884
-
-
Zhu, Y.L.1
Zheng, S.2
Du, Q.3
Qian, K.D.4
Fang, P.C.5
-
5
-
-
56749171378
-
Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA
-
Hatakeyama M, (2008) Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA. Oncogene 27: 7047-7054.
-
(2008)
Oncogene
, vol.27
, pp. 7047-7054
-
-
Hatakeyama, M.1
-
6
-
-
77955292149
-
Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein
-
Murata-Kamiya N, Kikuchi K, Hayashi T, Higashi H, Hatakeyama M, (2010) Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein. Cell Host Microbe 7: 399-411.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 399-411
-
-
Murata-Kamiya, N.1
Kikuchi, K.2
Hayashi, T.3
Higashi, H.4
Hatakeyama, M.5
-
7
-
-
77958016084
-
Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation
-
Tsang YH, Lamb A, Romero-Gallo J, Huang B, Ito K, et al. (2010) Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation. Oncogene 29: 5643-5650.
-
(2010)
Oncogene
, vol.29
, pp. 5643-5650
-
-
Tsang, Y.H.1
Lamb, A.2
Romero-Gallo, J.3
Huang, B.4
Ito, K.5
-
8
-
-
0038780624
-
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
-
Amieva MR, Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, et al. (2003) Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 300: 1430-1434.
-
(2003)
Science
, vol.300
, pp. 1430-1434
-
-
Amieva, M.R.1
Vogelmann, R.2
Covacci, A.3
Tompkins, L.S.4
Nelson, W.J.5
-
9
-
-
0037169076
-
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA Protein
-
Higashi H, Tsutsumi R, Muto S, Sugiyama T, Azuma T, et al. (2002) SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA Protein. Science 295: 683-686.
-
(2002)
Science
, vol.295
, pp. 683-686
-
-
Higashi, H.1
Tsutsumi, R.2
Muto, S.3
Sugiyama, T.4
Azuma, T.5
-
10
-
-
77952410241
-
Helicobacter pylori CagA phosphorylation status determines the gp130- activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells
-
Lee IO, Kim JH, Choi YJ, Pillinger MH, Kim SY, et al. (2010) Helicobacter pylori CagA phosphorylation status determines the gp130- activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. J Biol Chem 285: 16042-16050.
-
(2010)
J Biol Chem
, vol.285
, pp. 16042-16050
-
-
Lee, I.O.1
Kim, J.H.2
Choi, Y.J.3
Pillinger, M.H.4
Kim, S.Y.5
-
11
-
-
4544334936
-
Oncogenic mechanisms of the Helicobacter pylori CagA protein
-
Hatakeyama M, (2004) Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer 4: 688-694.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 688-694
-
-
Hatakeyama, M.1
-
12
-
-
20544440341
-
Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen- activated protein kinase pathway
-
Zhu Y, Zhong X, Zheng S, Du Q, Xu W, (2005) Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen- activated protein kinase pathway. Oncogene 24: 3886-3895.
-
(2005)
Oncogene
, vol.24
, pp. 3886-3895
-
-
Zhu, Y.1
Zhong, X.2
Zheng, S.3
Du, Q.4
Xu, W.5
-
13
-
-
38949199463
-
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
-
Ohnishi N, Yuasa H, Tanaka S, Sawa H, Miura M, et al. (2008) Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci U S A 105: 1003-1008.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1003-1008
-
-
Ohnishi, N.1
Yuasa, H.2
Tanaka, S.3
Sawa, H.4
Miura, M.5
-
14
-
-
34249090814
-
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
-
Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, et al. (2007) Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature 447: 330-333.
-
(2007)
Nature
, vol.447
, pp. 330-333
-
-
Saadat, I.1
Higashi, H.2
Obuse, C.3
Umeda, M.4
Murata-Kamiya, N.5
-
16
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen CZ, Li L, Lodish HF, Bartel DP, (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303: 83-86.
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
17
-
-
65249093130
-
miR-375 maintains normal pancreatic alpha- and beta-cell mass
-
Poy MN, Hausser J, Trajkovski M, Braun M, Collins S, et al. (2009) miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A 106: 5813-5818.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5813-5818
-
-
Poy, M.N.1
Hausser, J.2
Trajkovski, M.3
Braun, M.4
Collins, S.5
-
18
-
-
28444449496
-
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
-
Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, et al. (2005) The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature 438: 671-674.
-
(2005)
Nature
, vol.438
, pp. 671-674
-
-
Hornstein, E.1
Mansfield, J.H.2
Yekta, S.3
Hu, J.K.4
Harfe, B.D.5
-
19
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, et al. (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138: 592-603.
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
-
20
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K, (2010) STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 39: 493-506.
-
(2010)
Mol Cell
, vol.39
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
Bulyk, M.L.4
Struhl, K.5
-
21
-
-
42449152333
-
MiR-15a and miR-16-1 cluster functions in human leukemia
-
Calin GA, Cimmino A, Fabbri M, Ferracin M, Wojcik SE, et al. (2008) MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A 105: 5166-5171.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5166-5171
-
-
Calin, G.A.1
Cimmino, A.2
Fabbri, M.3
Ferracin, M.4
Wojcik, S.E.5
-
22
-
-
77957748992
-
Up-regulated microRNA-146a negatively modulate Helicobacter pylori- induced inflammatory response in human gastric epithelial cells
-
Liu Z, Xiao B, Tang B, Li B, Li N, et al. (2010) Up-regulated microRNA-146a negatively modulate Helicobacter pylori- induced inflammatory response in human gastric epithelial cells. Microbes Infect 12: 854-863.
-
(2010)
Microbes Infect
, vol.12
, pp. 854-863
-
-
Liu, Z.1
Xiao, B.2
Tang, B.3
Li, B.4
Li, N.5
-
23
-
-
78649575094
-
MicroRNA signatures in Helicobacter pylori-infected gastric mucosa
-
Matsushima K, Isomoto H, Inoue N, Nakayama T, Hayashi T, et al. (2011) MicroRNA signatures in Helicobacter pylori-infected gastric mucosa. Intern J Cancer 128: 361-370.
-
(2011)
Intern J Cancer
, vol.128
, pp. 361-370
-
-
Matsushima, K.1
Isomoto, H.2
Inoue, N.3
Nakayama, T.4
Hayashi, T.5
-
24
-
-
67650421553
-
H.pylori eradication prevents the progression of gastric intestinal metaplasia in reflux esophagitis patients using long-term esomeprazole
-
Yang HB, Sheu BS, Wang ST, Cheng HC, Chang WL, et al. (2009) H.pylori eradication prevents the progression of gastric intestinal metaplasia in reflux esophagitis patients using long-term esomeprazole. Am J Gastroenterol 104: 1642-1649.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1642-1649
-
-
Yang, H.B.1
Sheu, B.S.2
Wang, S.T.3
Cheng, H.C.4
Chang, W.L.5
-
25
-
-
29744467037
-
OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells
-
Almeida R, Almeida J, Shoshkes M, Mendes N, Mesquita P, et al. (2005) OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells. J Pathol 207: 396-401.
-
(2005)
J Pathol
, vol.207
, pp. 396-401
-
-
Almeida, R.1
Almeida, J.2
Shoshkes, M.3
Mendes, N.4
Mesquita, P.5
-
26
-
-
0036892969
-
Helicobacter pylori CagA protein activates serum response element-driven transcription independently of tyrosine phosphorylation
-
Hirata Y, Maeda S, Mitsuno Y, Tateishi K, Yanai A, et al. (2002) Helicobacter pylori CagA protein activates serum response element-driven transcription independently of tyrosine phosphorylation. Gastroenterology 123: 1962-1971.
-
(2002)
Gastroenterology
, vol.123
, pp. 1962-1971
-
-
Hirata, Y.1
Maeda, S.2
Mitsuno, Y.3
Tateishi, K.4
Yanai, A.5
-
27
-
-
67651002855
-
Foxa1 and Foxa2 regulate bile duct development in mice
-
Li Z, White P, Tuteja G, Rubins N, Sackett S, et al. (2009) Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest 119: 1537-1545.
-
(2009)
J Clin Invest
, vol.119
, pp. 1537-1545
-
-
Li, Z.1
White, P.2
Tuteja, G.3
Rubins, N.4
Sackett, S.5
-
28
-
-
17144407948
-
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis
-
Wan H, Dingle S, Xu Y, Besnard V, Kaestner KH, et al. (2005) Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem 280: 13809-13816.
-
(2005)
J Biol Chem
, vol.280
, pp. 13809-13816
-
-
Wan, H.1
Dingle, S.2
Xu, Y.3
Besnard, V.4
Kaestner, K.H.5
-
29
-
-
33750857693
-
Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation
-
Vatamaniuk MZ, Gupta RK, Lantz KA, Doliba NM, Matschinsky FM, et al. (2006) Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation. Diabetes 55: 2730-2736.
-
(2006)
Diabetes
, vol.55
, pp. 2730-2736
-
-
Vatamaniuk, M.Z.1
Gupta, R.K.2
Lantz, K.A.3
Doliba, N.M.4
Matschinsky, F.M.5
-
30
-
-
24344447360
-
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation
-
Gao N, Ishii K, Mirosevich J, Kuwajima S, Oppenheimer SR, et al. (2005) Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Development 132: 3431-3443.
-
(2005)
Development
, vol.132
, pp. 3431-3443
-
-
Gao, N.1
Ishii, K.2
Mirosevich, J.3
Kuwajima, S.4
Oppenheimer, S.R.5
-
31
-
-
70949092295
-
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice
-
Ye DZ, Kaestner KH, (2009) Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology 137: 2052-2062.
-
(2009)
Gastroenterology
, vol.137
, pp. 2052-2062
-
-
Ye, D.Z.1
Kaestner, K.H.2
-
32
-
-
0035666793
-
Relationship between Helicobacter pylori CagA status and colorectal cancer
-
Shmuely H, Passaro D, Figer A, Niv Y, Pitlik S, et al. (2001) Relationship between Helicobacter pylori CagA status and colorectal cancer. Am J Gastroenterol 96: 3406-3410.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 3406-3410
-
-
Shmuely, H.1
Passaro, D.2
Figer, A.3
Niv, Y.4
Pitlik, S.5
-
33
-
-
78751581958
-
Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma
-
Ueno K, Hirata H, Shahryari V, Chen Y, Zaman MS, et al. (2011) Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma. Br J Cancer 104: 308-315.
-
(2011)
Br J Cancer
, vol.104
, pp. 308-315
-
-
Ueno, K.1
Hirata, H.2
Shahryari, V.3
Chen, Y.4
Zaman, M.S.5
-
34
-
-
77950541769
-
Effect of YB-1 on the regulation of micro RNA expression in drug-sensitive and drug-resistant gastric carcinoma cells
-
Belian E, Kurucz R, Treue D, Lage H, (2010) Effect of YB-1 on the regulation of micro RNA expression in drug-sensitive and drug-resistant gastric carcinoma cells. Anticancer Res 30: 629-633.
-
(2010)
Anticancer Res
, vol.30
, pp. 629-633
-
-
Belian, E.1
Kurucz, R.2
Treue, D.3
Lage, H.4
-
35
-
-
77956435525
-
Increased levels of FoxA1 transcription factor in pluripotent P19 embryonal carcinoma cells stimulate neural differentiation
-
Tan Y, Xie Z, Ding M, Wang Z, Yu Q, et al. (2010) Increased levels of FoxA1 transcription factor in pluripotent P19 embryonal carcinoma cells stimulate neural differentiation. Stem Cells Dev 19: 1365-13674.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 1365-13674
-
-
Tan, Y.1
Xie, Z.2
Ding, M.3
Wang, Z.4
Yu, Q.5
-
36
-
-
77952354898
-
Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells
-
Taube JH, Allton K, Duncan SA, Shen L, Barton MC, (2010) Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem 285: 16135-16144.
-
(2010)
J Biol Chem
, vol.285
, pp. 16135-16144
-
-
Taube, J.H.1
Allton, K.2
Duncan, S.A.3
Shen, L.4
Barton, M.C.5
-
37
-
-
40849085514
-
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
-
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, et al. (2008) FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132: 958-970.
-
(2008)
Cell
, vol.132
, pp. 958-970
-
-
Lupien, M.1
Eeckhoute, J.2
Meyer, C.A.3
Wang, Q.4
Zhang, Y.5
-
38
-
-
0035872426
-
Transforming growth factor beta1 treatment leads to an epithelial- mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation
-
Ellenrieder V, Hendler SF, Boeck W, Seufferlein T, Menke A, et al. (2001) Transforming growth factor beta1 treatment leads to an epithelial- mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. Cancer Res 61: 4222-4228.
-
(2001)
Cancer Res
, vol.61
, pp. 4222-4228
-
-
Ellenrieder, V.1
Hendler, S.F.2
Boeck, W.3
Seufferlein, T.4
Menke, A.5
-
39
-
-
0035185853
-
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
-
Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, et al. (2001) Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol Biol Cell 12: 27-36.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
-
40
-
-
59449090107
-
TGF-β-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S, Derynck R, (2009) TGF-β-induced epithelial to mesenchymal transition. Cell Res 19: 156-172.
-
(2009)
Cell Res
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
|