The mRNA expression of BRCA1, ERCC1, TUBB3, PRR13 genes and their relationship with clinical chemosensitivity in primary epithelial ovarian cancer

Chinese Journal of Oncology

Volumn 34, Issue 3, 2012, Pages 196-200

  Zhao, Dan ^a   Zhang, Wei ^b   Li, Xiao Guang ^b   Wang, Xiao Bing ^b   Li, Mo ^b   Li, Yan Fen ^b   Tian, Hai Mei ^b   Song, Pei Pei ^b   Liu, Jing ^b   Chang, Qing Yun ^b   Wu, Ling Ying ^b  

^a CANCER HOSPITAL   (China)

^b NONE

Author keywords

Breast cancer susceptibility gene 1; Drug resistance, neoplasm; Excision repair cross complementation group 1; Ovarian neoplasms; Proline rich 13; tubulin III

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; BETA TUBULIN III; BRCA1 PROTEIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MESSENGER RNA; PROLINE RICH 13 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMOSENSITIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; OVARY CANCER; PREDICTIVE VALUE; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84859963037     PISSN: 02533766     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0253-3766.2012.03.008     Document Type: Article

References (9)

1. Aunoble B, Sanches R, Didier E, et al. Major oncogenes and tumor suppressor genes involved in epithelial ovarian cancer (review). Int J Oncol, 2000, 16:567-576.
2. Quinn JE, James CR, Stewart GE, et al. BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy. Clin Cancer Res, 2007, 13:7413-7420.
3. Taron M, Rosell R, Felip E, et al. BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer. Hum Mol Genet, 2004, 13:2443-2449. (Pubitemid 39377848)
4. van Duin M, de Wit J, Odijk H, et al. Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RADIO. Cell, 1986, 44:913-923. (Pubitemid 16045337)
5. Mozzetti S, Ferlini C, Concolino P, et al. Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients. Clin Cancer Res, 2005, 11:298-305. (Pubitemid 40075808)
6. Ohishi Y, Oda Y, Basaki Y, et al. Expression of beta-tubulin isotypes in human primary ovarian carcinoma. Gynecol Oncol, 2007, 105:586-592. (Pubitemid 46734190)
7. Lih CJ, Wei W, Cohen SN. Txrl: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev, 2006, 20:2082-2095. (Pubitemid 44157459)
8. Papadaki C, Mavroudis D, Trypaki M, et al. Tumoral expression of TXR1 and TSP1 predicts overall survival of patients with lung adenocarcinoma treated with first-line docetaxel-gemcitabine regimen. Clin Cancer Res, 2009, 15:3827-3833.