Intravenous immunoglobulins modulate neutrophil activation and vascular injury through fcγRIII and SHP-1

Circulation Research

Volumn 110, Issue 8, 2012, Pages 1057-1066

  Jang, Jung Eun ^a,b   Hidalgo, Andrés ^c   Frenette, Paul S ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

adhesion molecules; endothelial cells; Fc; inflammation; intravenous immunoglobulin; neutrophils; RIII; Src homology 2 containing tyrosine phosphatase 1; vascular injury

Indexed keywords

ALBUMIN; CD16 ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G2B; MONOCLONAL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE SHP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; ERYTHROCYTE; FLOW CYTOMETRY; HEMODYNAMIC PARAMETERS; LEUKOCYTE; LEUKOCYTE ACTIVATION; MICROSCOPY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SICKLE CELL ANEMIA; VASCULAR DISEASE; VEIN OCCLUSION; WESTERN BLOTTING; WILD TYPE;

ANEMIA, SICKLE CELL; ANIMALS; CONSTRICTION, PATHOLOGIC; ENDOTHELIAL CELLS; ERYTHROCYTES; IMMUNOGLOBULINS, INTRAVENOUS; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, VIDEO; MUSCLE, SMOOTH; NEUTROPHIL ACTIVATION; NEUTROPHILS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, IGG; TIME FACTORS; VASCULAR DISEASES; VENULES;

EID: 84859913621     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.266411     Document Type: Article

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