Optimization of cardiovascular stent design using computational fluid dynamics

Journal of Biomechanical Engineering

Volumn 134, Issue 1, 2012, Pages

  Gundert, Timothy J ^a   Marsden, Alison L ^b   Yang, Weiguang ^b   Ladisa, John F ^a,c,d  

^a Marquette University   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d Children's Hospital of Wisconsin   (United States)

Author keywords

cardiovascular stent; computational fluid dynamics; coronary artery disease; optimization; wall shear stress

Indexed keywords

ANISOTROPIC MESH GENERATION; CARDIOVASCULAR STENTS; CFD SIMULATIONS; CLINICAL OUTCOME; COMPUTATIONAL FLUID DYNAMIC (CFD); CORONARY ARTERY DISEASE; CORONARY STENTS; ENDOTHELIALIZATION; FUTURE APPLICATIONS; NEAR-WALL; NEOINTIMAL HYPERPLASIA; OPTIMAL NUMBER; OPTIMAL VALUES; OPTIMIZATION METHOD; OPTIMIZATION PROCEDURES; PRIMARY FLOW; RESTENOSIS; SOLID MODEL; STENT DESIGN; TIME-AVERAGED; USER INTERVENTION; VESSEL SIZE; WALL SHEAR STRESS;

COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; DESIGN; DISEASES; OPTIMIZATION;

STENTS;

ANISOTROPY; ARTICLE; COMPUTATIONAL FLUID DYNAMICS; CORONARY STENT; EQUIPMENT DESIGN; SHEAR STRESS; SIMULATION; CARDIOVASCULAR SYSTEM; HYDRODYNAMICS; MECHANICAL STRESS; METHODOLOGY; STENT; TIME;

CARDIOVASCULAR SYSTEM; EQUIPMENT DESIGN; HYDRODYNAMICS; STENTS; STRESS, MECHANICAL; TIME FACTORS;

EID: 84859910828     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4005542     Document Type: Article

References (52)

1. Doyle, B., Rihal, C. S., O'Sullivan, C. J., Lennon, R. J., Wiste, H. J., Bell, M., Bresnahan, J., and Holmes, D. R., 2007, Outcomes of Stent Thrombosis and Restenosis During Extended Follow-Up of Patients Treated With Bare-Metal Coronary Stents., Circulation, 116 (21), pp. 2391-2398. (Pubitemid 350145074)
2. James, S. K., Stenestrand, U., Lindbäck, J., Carlsson, J., Scherstén, F., Nilsson, T., Wallentin, L., Lagerqvist, B., and Group, S. S., 2009, Long-Term Safety and Efficacy of Drug-Eluting Versus Bare-Metal Stents in Sweden., N. Engl. J. Med., 360 (19), pp. 1933-1945.
3. Stone, G. W., Rizvi, A., Sudhir, K., Newman, W., Applegate, R. J., Cannon, L. A., Maddux, J. T., Cutlip, D. E., Simonton, C. A., Sood, P., Kereiakes, D. J., and Investigators, S. I., 2011, Randomized Comparison of Everolimus- and Paclitaxel-Eluting Stents. 2-Year Follow-Up From the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV Trial., J. Am. Coll. Cardiol., 58 (1), pp. 19-25.
4. Leon, M. B., Kandzari, D. E., Eisenstein, E. L., Anstrom, K. J., Mauri, L., Cutlip, D. E., Nikolsky, E., O'Shaughnessy, C., Overlie, P. A., Kirtane, A. J., McLaurin, B. T., Solomon, S. L., Douglas, J. S., Popma, J. J., and Investigators, E. I., 2009, Late Safety, Efficacy, and Cost-Effectiveness of a Zotarolimus-Eluting Stent Compared With a Paclitaxel-Eluting Stent in Patients With De Novo Coronary Lesions: 2-Year Follow-Up From the ENDEAVOR IV Trial (Randomized, Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions). JACC Cardiovasc. Interv., 2 (12), pp. 1208-1218.
5. Finn, A. V., Nakazawa, G., Joner, M., Kolodgie, F. D., Mont, E. K., Gold, H. K., and Virmani, R., 2007, Vascular Responses to Drug Eluting Stents: Importance of Delayed Healing., Arterioscler., Thromb., Vasc. Biol., 27 (7), pp. 1500-1510. (Pubitemid 46986103)
6. Joner, M., Nakazawa, G., Finn, A. V., Quee, S. C., Coleman, L., Acampado, E., Wilson, P. S., Skorija, K., Cheng, Q., Xu, X., Gold, H. K., Kolodgie, F. D., and Virmani, R., 2008, Endothelial Cell Recovery Between Comparator Polymer-Based Drug-Eluting Stents., J. Am. Coll. Cardiol., 52 (5), pp. 333-342. (Pubitemid 352001347)
7. Kotani, J., Awata, M., Nanto, S., Uematsu, M., Oshima, F., Minamiguchi, H., Mintz, G. S., and Nagata, S., 2006, Incomplete Neointimal Coverage of Sirolimus-Eluting Stents: Angioscopic Findings., J. Am. Coll. Cardiol., 47 (10), pp. 2108-2111.
8. LaDisa, J. F., Olson, L. E., Molthen, R. C., Hettrick, D. A., Pratt, P. F., Hardel, M. D., Kersten, J. R., Warltier, D. C., and Pagel, P. S., 2005, Alterations in Wall Shear Stress Predict Sites of Neointimal Hyperplasia After Stent Implantation in Rabbit Iliac Arteries., Am. J. Physiol. Heart Circ. Physiol., 288 (5), pp. H2465-2475.
9. and Liu, S. Q. and Goldman, J., 2001, Role of Blood Shear Stress in the Regulation of Vascular Smooth Muscle Cell Migration., IEEE Trans. Biomed. Eng., 48 (4), pp. 474-483. (Pubitemid 32289881)
10. Sprague, E. A., Luo, J., and Palmaz, J. C., 2000, Endothelial Cell Migration Onto Metal Stent Surfaces Under Static and Flow Conditions., J. Long Term Eff. Med. Implants, 10 (1-2), pp. 97-110. Available at http://dl. begellhouse.com/journals/1bef42082d7a0fdf,10a09db02be3aae4,2689d22927f48a2a. html. (Pubitemid 30387809)
11. LaDisa, J. F., Olson, L. E., Guler, I., Hettrick, D. A., Audi, S. H., Kersten, J. R., Warltier, D., and Pagel, P. S., 2004, Stent Design Properties and Deployment Ratio Influence Indexes of Wall Shear Stress: A Three-Dimensional Computational Fluid Dynamics Investigation Within a Normal Artery., J. Appl. Physiol., 97 (1), pp. 424-430. (Pubitemid 38802547)
12. He, Y., Duraiswamy, N., Frank, A. O., and Moore, J. E., 2005, Blood Flow in Stented Arteries: A Parametric Comparison of Strut Design Patterns in three Dimensions., ASME J. Biomech. Eng., 127 (4), pp. 637-647. (Pubitemid 41116923)
13. Duraiswamy, N., Schoephoerster, R. T., and Moore, J. E., 2009, Comparison of Near-Wall Hemodynamic Parameters in Stented Artery Models., ASME J. Biomech Eng, 131 (6), p. 061006.
14. Murphy, J. B. and Boyle, F. J., 2010, A Full-Range, Multi-Variable, CFD-Based Methodology to Identify Abnormal Near-Wall Hemodynamics in a Stented Coronary Artery., Biorheology, 47 (2), pp. 117-132.
15. LaDisa, J. F., Olson, L. E., Hettrick, D. A., Warltier, D. C., Kersten, J. R., and Pagel, P. S., 2005, Axial Stent Strut Angle Influences Wall Shear Stress After Stent Implantation: Analysis Using 3D Computational Fluid Dynamics Models of Stent Foreshortening., Biomed. Eng. Online, 4, p. 59.
16. Gundert, T. J., Shadden, S. C., Williams, A. R., Koo, B. K., Feinstein, J. A., and Ladisa, J. F., 2011, A Rapid and Computationally Inexpensive Method to Virtually Implant Current and Next-Generation Stents into Subject-Specific Computational Fluid Dynamics Models., Ann. Biomed. Eng., 39 (5), pp. 1423-1437.
17. Blouza, A., Dumas, L., And M'Baye, I., 2008, Multiobjective Optimization of a Stent in a Fluid-Structure Context., Proceedings of the 2008 GECCO Conference Companion on Genetic and Evolutionary Computation, ACM, Atlanta, GA, USA, pp. 2055-2060.
18. Srinivas, K., Nakayama, T., Ohta, M., Obayashi, S., and Yamaguchi, T., 2008, Studies on Design Optimization of Coronary Stents., ASME J Med. Devices, 2 (1), p. 011004.
19. Atherton, M. A. and Bates, R. A., 2004, Robust Optimization of Cardiovascular Stents: A Comparison of Methods., Eng. Optimiz., 36 (2), pp. 207-217.
20. Garasic, J. M., Edelman, E. R., Squire, J. C., Seifert, P., Williams, M. S., and Rogers, C., 2000, Stent and Artery Geometry Determine Intimal Thickening Independent of Arterial Injury., Circulation, 101 (7), pp. 812-818. Available at http://circ.ahajournals.org/content/101/7/812. (Pubitemid 30100090)
21. LaDisa, J. F., Hettrick, D. A., Olson, L. E., Guler, I., Gross, E. R., Kress, T. T., Kersten, J. R., Warltier, D. C., and Pagel, P. S., 2002, Stent Implantation Alters Coronary Artery Hemodynamics and Wall Shear Stress During Maximal Vasodilation., J. Appl. Physiol., 93 (6), pp. 1939-1946. (Pubitemid 35379317)
22. Vignon-Clementel, I. E., Alberto Figueroa, C., Jansen, K. E., and Taylor, C. A., 2006, Outflow Boundary Conditions for Three-Dimensional Finite Element Modeling of Blood Flow and Pressure in Arteries., Comput. Methods Appl. Mech. Eng., 195 (29-32), pp. 3776-3796.
23. Ellwein, L., Otake, H., Gundert, T., Koo, B.-K., Shinke, T., Honda, Y., Shite, J., and LaDisa, J., 2011, Optical Coherence Tomography for Patient-Specific 3D Artery Reconstruction and Evaluation of Wall Shear Stress in a Left Circumflex Coronary Artery., Cardiovasc. Eng. Technol., 2 (3), pp. 212-227.
24. Williams, A. R., Koo, B. K., Gundert, T. J., Fitzgerald, P. J., and LaDisa, J. F., 2010, Local Hemodynamic Changes Caused by Main Branch Stent Implantation and Subsequent Virtual Side Branch Balloon Angioplasty in A Representative Coronary Bifurcation., J. Appl. Physiol., 109 (2), pp. 532-540.
25. Tang, B., Cheng, C., Draney, M., Wilson, N., Tsao, P., Herfkens, R., and Taylor, C., 2006, Abdominal Aortic Hemodynamics in Young Healthy Adults at Rest and During Lower Limb Exercise: Quantification Using Image-Based Computer Modeling., Am. J. Physiol. Heart Circ. Physiol., 291 (2), pp. H668-H676.
26. Glagov, S., Weisenberg, E., Zarins, C. K., Stankunavicius, R., and Kolettis, G. J., 1987, Compensatory Enlargement of Human Atherosclerotic Coronary Arteries., N. Engl. J. Med., 316 (22), pp. 1371-1375. (Pubitemid 17079680)
27. Kamiya, A. and Togawa, T., 1980, Adaptive Regulation of Wall Shear Stress to Flow Change in the Canine Carotid Artery., Am. J. Physiol. Heart Circ. Physiol., 239 (1), pp. H14-H21. Available at http://ajpheart.physiology.org/ content/239/1/H14.abstract.
28. Booker, A. J., Dennis, J. E., Frank, P. D., Serafini, D. B., Torczon, V., and Trosset, M. W., 1999, A Rigorous Framework for Optimization of Expensive Functions by Surrogates., Struct. Multidiscip. Optimiz., 17 (1), pp. 1-13.
29. Marsden, A. L., Feinstein, J. A., and Taylor, C. A., 2008, A Computational Framework for Derivative-Free Optimization of Cardiovascular Geometries., Comput. Methods Appl. Mech. Eng., 197 (21-24), pp. 1890-1905.
30. Audet, C. and Dennis, J. J. E., 2006, Mesh Adaptive Direct Search Algorithms for Constrained Optimization., SIAM J. Optim., 17 (1), pp. 188-217.
31. Lophaven, S., Nielsen, H., Sndergaard, J., 2002, DACE-A MATLAB Kriging Toolbox Version 2.0., Technical University of Denmark, Copenhagen, Technical Report IMM-TR-2002-12M.
32. McKay, M. D., Beckman, R. J., and Conover, W., 1979, A Comparison of Three Methods for Selecting Values of Input Variables in the Analysis of Output from a Computer Code., Technometrics, 21 (2), pp. 239-245. (Pubitemid 9452235)
33. Rogers, C. and Edelman, E. R., 1995, Endovascular Stent Design Dictates Experimental Restenosis and Thrombosis., Circulation, 91 (12), pp. 2995-3001. Available at http://circ.ahajournals.org/content/91/12/2995.short.
34. Pache, J., Kastrati, A., Mehilli, J., Schühlen, H., Dotzer, F., Hausleiter, J., Fleckenstein, M., Neumann, F. J., Sattelberger, U., Schmitt, C., Müller, M., Dirschinger, J., and Schömig, A., 2003, Intracoronary Stenting and Angiographic Results: Strut Thickness Effect on Restenosis Outcome (ISAR-STEREO-2) Trial., J. Am. Coll. Cardiol., 41 (8), pp. 1283-1288. (Pubitemid 36438988)
35. Finn, A. V., Kolodgie, F. D., Harnek, J., Guerrero, L. J., Acampado, E., Tefera, K., Skorija, K., Weber, D. K., Gold, H. K., and Virmani, R., 2005, Differential Response of Delayed Healing and Persistent Inflammation at Sites of Overlapping Sirolimus- or Paclitaxel-Eluting Stents., Circulation, 112 (2), pp. 270-278. (Pubitemid 40982311)
36. LaDisa, J. F., Guler, I., Olson, L. E., Hettrick, D. A., Kersten, J. R., Warltier, D. C., and Pagel, P. S., 2003, Three-Dimensional Computational Fluid Dynamics Modeling of Alterations in Coronary Wall Shear Stress Produced by Stent Implantation., Ann. Biomed. Eng., 31 (8), pp. 972-980.
37. Balossino, R., Gervaso, F., Migliavacca, F., and Dubini, G., 2008, Effects of Different Stent Designs on Local Hemodynamics in Stented Arteries., J. Biomech., 41 (5), pp. 1053-1061.
38. LaDisa, J. F., Olson, L. E., Guler, I., Hettrick, D. A., Kersten, J. R., Warltier, D. C., and Pagel, P. S., 2005, Circumferential Vascular Deformation After Stent Implantation Alters Wall Shear Stress Evaluated With Time-Dependent 3D Computational Fluid Dynamics Models., J. Appl. Physiol., 98 (3), pp. 947-957. (Pubitemid 40283676)
39. Ku, D. N., Giddens, D. P., Zarins, C. K., and Glagov, S., 1985, Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation. Positive Correlation Between Plaque Location and Low Oscillating Shear Stress., Arteriosclerosis, 5 (3), pp. 293-302. (Pubitemid 15098005)
40. Fletcher, R. and Leyffer, S., 2002, Nonlinear Programming Without a Penalty Function., Math. Program., 91 (2), pp. 239-269. (Pubitemid 44744779)
41. Audet, C. and Dennis, J. J. E., 2004, A Pattern Search Filter Method for Nonlinear Programming Without Derivatives., SIAM J. Optim., 14 (4), pp. 980-1010.
42. Yang, W., Feinstein, J. A., and Marsden, A. L., 2010, Constrained Optimization of an Idealized Y-Shaped Baffle for the Fontan Surgery at Rest and Exercise., Comput. Methods Appl. Mech. Eng., 199 (33-36), pp. 2135-2149.
43. Longest, P. W. and Kleinstreuer, C., 2000, Computational Haemodynamics Analysis and Comparison Study of Arterio-Venous Grafts., J. Med. Eng. Technol., 24 (3), pp. 102-110.
44. Lei, M., Kleinstreuer, C., and Truskey, G. A., 1996, A Focal Stress Gradient-Dependent Mass Transfer Mechanism for Atherogenesis in Branching Arteries., Med. Eng. Phys., 18 (4), pp. 326-332. (Pubitemid 26185100)
45. He, X. and Ku, D. N., 1996, Pulsatile Flow in the Human Left Coronary Artery Bifurcation: Average Conditions., ASME J. Biomech. Eng., 118 (1), pp. 74-82. (Pubitemid 26087285)
46. Zahedmanesh, H. and Lally, C., 2009, Determination of the Influence of Stent Strut Thickness Using the Finite Element Method: Implications for Vascular Injury and In-Stent Restenosis., Med. Biol. Eng. Comput., 47 (4), pp. 385-393.
47. Bedoya, J., Meyer, C. A., Timmins, L. H., Moreno, M. R., and Moore, J. E., 2006, Effects of Stent Design Parameters on Normal Artery Wall Mechanics., ASME J. Biomech. Eng., 128 (5), pp. 757-765. (Pubitemid 44622805)
48. Lally, C., Dolan, F., and Prendergast, P. J., 2005, Cardiovascular Stent Design and Vessel Stresses: A Finite Element Analysis., J. Biomech., 38 (8), pp. 1574-1581. (Pubitemid 40813479)
49. Ako, J., Bonneau, H. N., Honda, Y., and Fitzgerald, P. J., 2007, Design Criteria for the Ideal Drug-Eluting Stent., Am. J. Cardiol., 100 (8B), pp. 3M-9M.
50. Timmins, L. H., Moreno, M. R., Meyer, C. A., Criscione, J. C., Rachev, A., and Moore, J. E., 2007, Stented Artery Biomechanics and Device Design Optimization., Med. Biol. Eng. Comput., 45 (5), pp. 505-513. (Pubitemid 46681624)
51. Balakrishnan, B., Tzafriri, A. R., Seifert, P., Groothuis, A., Rogers, C., and Edelman, E. R., 2005, Strut Position, Blood Flow, and Drug Deposition: Implications for Single and Overlapping Drug-Eluting Stents., Circulation, 111 (22), pp. 2958-2965. (Pubitemid 40814189)
52. Murphy, J. and Boyle, F., 2008, Assessment of the Effects of Increasing Levels of Physiological Realism in the Computational Fluid Dynamics Analyses of Implanted Coronary Stents., IEEE Conf. Proc. Eng. Med. Biol. Soc., 2008, pp. 5906-5909.