In vitro articular cartilage growth with sequential application of IGF-1 and TGF-β1 enhances volumetric growth and maintains compressive properties

Journal of Biomechanical Engineering

Volumn 134, Issue 3, 2012, Pages

  Balcom, Nathan T ^a   Berg Johansen, Britta ^a   Dills, Kristin J ^a   Van Donk, Jennifer R ^a   Williams, Gregory M ^b   Chen, Albert C ^b   Hazelwood, Scott J ^a   Sah, Robert L ^c   Klisch, Stephen M ^a  

^a CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

articular cartilage; confined compression; growth; IGF 1; Poisson's ratio; TGF 1; unconfined compression

Indexed keywords

ARTICULAR CARTILAGES; CONFINED COMPRESSION; IGF-1; POISSON'S RATIO; TGF-1; UNCONFINED COMPRESSION;

CARTILAGE; GEOMETRY; GROWTH (MATERIALS); MAMMALS; PEPTIDES; POISSON RATIO; TISSUE;

BIOMECHANICS;

SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CELL GROWTH; COMPRESSION; FORCE; GEOMETRY; IN VITRO STUDY; MECHANICAL STRESS; NONHUMAN; WATER CONTENT; YOUNG MODULUS; ANIMAL; BIOMECHANICS; CATTLE; COMPRESSIVE STRENGTH; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; TIME; TISSUE CULTURE TECHNIQUE; TRANSPLANTATION;

BOVINAE;

ANIMALS; BIOMECHANICS; CARTILAGE, ARTICULAR; CATTLE; COMPRESSIVE STRENGTH; INSULIN-LIKE GROWTH FACTOR I; TIME FACTORS; TISSUE CULTURE TECHNIQUES; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTS;

EID: 84859910292     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4005851     Document Type: Article

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