The 3-layered ductal epithelium in gynecomastia

American Journal of Surgical Pathology

Volumn 36, Issue 5, 2012, Pages 762-768

  Kornegoor, Robert ^a   Verschuur Maes, Anoek H J ^a   Buerger, Horst ^b   Van Diest, Paul J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Institute of Pathology   (Germany)

Author keywords

cytokeratin; gynecomastia; immunohistochemistry; male

Indexed keywords

BIOLOGICAL MARKER; TUMOR MARKER;

ARTICLE; BREAST TUMOR; GYNECOMASTIA; HUMAN; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; MALE; MAMMARY GLAND; METABOLISM; PATHOLOGY; TISSUE MICROARRAY;

BIOLOGICAL MARKERS; BREAST NEOPLASMS, MALE; CARCINOMA, INTRADUCTAL, NONINFILTRATING; GYNECOMASTIA; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MAMMARY GLANDS, HUMAN; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84859908267     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31824324e6     Document Type: Article

References (29)

1. Abdel-Fatah TM, Powe DG, Hodi Z, et al. Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family. Am J Surg Pathol. 2008; 32: 513-523. (Pubitemid 351458293)
2. Boecker W, Buerger H. Evidence of progenitor cells of glandular and myoepithelial cell lineages in the human adult female breast epithelium: a new progenitor (adult stem) cell concept. Cell Prolif. 2003; 36(suppl 1): 73-84. (Pubitemid 37521845)
3. Boecker W, Moll R, Dervan P, et al. Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ. J Pathol. 2002; 198: 458-467. (Pubitemid 35446999)
4. Bratton MR, Duong BN, Elliott S, et al. Regulation of ERalphamediated transcription of Bcl-2 by PI3K-AKT crosstalk: implications for breast cancer cell survival. Int J Oncol. 2010; 37: 541-550.
5. Braunstein GD. Clinical practice. Gynecomastia. N Engl J Med. 2007; 357: 1229-1237.
6. Braunstein GD. Gynecomastia. N Engl J Med. 1993; 328: 490-495. (Pubitemid 23056441)
7. Brinton LA, Carreon JD, Gierach GL, et al. Etiologic factors for male breast cancer in the U.S. Veterans Affairs medical care system database. Breast Cancer Res Treat. 2010; 119: 185-192.
8. Callagy GM, Pharoah PD, Pinder SE, et al. Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index. Clin Cancer Res. 2006; 12: 2468-2475.
9. Chang HL, Kish JB, Smith BL, et al. A 16-year-old male with gynecomastia and ductal carcinoma in situ. Pediatr Surg Int. 2008; 24: 1251-1253.
10. Ciocca V, Bombonati A, Gatalica Z, et al. Cytokeratin profiles of male breast cancers. Histopathology. 2006; 49: 365-370. (Pubitemid 44401543)
11. Eckman A, Dobs A. Drug-induced gynecomastia. Expert Opin Drug Saf. 2008; 7: 691-702.
12. Fentiman IS, Fourquet A, Hortobagyi GN. Male breast cancer. Lancet. 2006; 367: 595-604. (Pubitemid 43247575)
13. Ferreira M, Mesquita M, Quaresma M, et al. Prolactin receptor expression in gynaecomastia and male breast carcinoma. Histopathology. 2008; 53: 56-61. (Pubitemid 351861981)
14. Hamady ZZ, Carder PJ, Brennan TG. Atypical ductal hyperplasia in male breast tissue with gynaecomastia. Histopathology. 2005; 47: 111-112. (Pubitemid 40978820)
15. Heller KS, Rosen PP, Schottenfeld D, et al. Male breast cancer: a clinicopathologic study of 97 cases. Ann Surg. 1978; 188: 60-65. (Pubitemid 8373178)
16. Kalekou H, Kostopoulos I, Milias S, et al. Comparative study of CD34, alpha-SMA and h-caldesmon expression in the stroma of gynaecomastia and male breast carcinoma. Histopathology. 2005; 47: 74-81. (Pubitemid 40978816)
17. Kanhai RC, Hage JJ, van Diest PJ, et al. Short-term and long-term histologic effects of castration and estrogen treatment on breast tissue of 14 male-to-female transsexuals in comparison with two chemically castrated men. Am J Surg Pathol. 2000; 24: 74-80. (Pubitemid 30033399)
18. Kono S, Kurosumi M, Simooka H, et al. Immunohistochemical study of the relationship between Ki-67 labeling index of proliferating cells of gynecomastia, histological phase and duration of disease. Pathol Int. 2006; 56: 655-658. (Pubitemid 44570014)
19. Kornegoor R, Verschuur-Maes AH, Buerger H, et al. Molecular subtyping of male breast cancer by immunohistochemistry. Mod Pathol. 2011.
20. Milanezi MF, Saggioro FP, Zanati SG, et al. Pseudoangiomatous hyperplasia of mammary stroma associated with gynaecomastia. J Clin Pathol. 1998; 51: 204-206. (Pubitemid 28216075)
21. Munoz Carrasco R, Alvarez Benito M, Munoz Gomariz E, et al. Mammography and ultrasound in the evaluation of male breast disease. Eur Radiol. 2010; 20: 2797-2805.
22. Prasad V, M King J, McLeay W, et al. Bilateral atypical ductal hyperplasia, an incidental finding in gynaecomastia-case report and literature review. Breast. 2005; 14: 317-321. (Pubitemid 41110194)
23. Rosen PP. Benign proliferative lesions of the male breast. Rosen's Breast Pathology. Philadelphia: Lippincott Williams & Wilkins, a Wolters Kluwer Business; 2009: 777-785.
24. Sasco AJ, Lowenfels AB, Pasker-de Jong P. Review article: epidemiology of male breast cancer. A meta-analysis of published case-control studies and discussion of selected aetiological factors. Int J Cancer. 1993; 53: 538-549. (Pubitemid 23069261)
25. Shoker BS, Jarvis C, Sibson DR, et al. Oestrogen receptor expression in the normal and pre-cancerous breast. J Pathol. 1999; 188: 237-244. (Pubitemid 29317764)
26. Simpson E, Rubin G, Clyne C, et al. The role of local estrogen biosynthesis in males and females. Trends Endocrinol Metab. 2000; 11: 184-188. (Pubitemid 30457139)
27. Subramanian A, Salhab M, Mokbel K. Oestrogen producing enzymes and mammary carcinogenesis: a review. Breast Cancer Res Treat. 2008; 111: 191-202.
28. van der Groep P, van Diest PJ, Menko FH, et al. Molecular profile of ductal carcinoma in situ of the breast in BRCA1 and BRCA2 germline mutation carriers. J Clin Pathol. 2009; 62: 926-930.
29. Yue W, Wang JP, Hamilton CJ, et al. In situ aromatization enhances breast tumor estradiol levels and cellular proliferation. Cancer Res. 1998; 58: 927-932. (Pubitemid 28182460)