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Volumn 20, Issue 9, 2012, Pages 3094-3099
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Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs
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Author keywords
Anti cancer agents; Diazeniumdiolate prodrugs; Glutathione; JS K; Nitric oxide
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Indexed keywords
ANTINEOPLASTIC AGENT;
DIAZENIUMDIOLATE DERIVATIVE;
DIAZENIUMDIOLATE SODIUM CHLORIDE;
FLUOROBENZENE DERIVATIVE;
GLUTATHIONE;
NITRIC OXIDE;
PIPERAZINE DERIVATIVE;
PRODRUG;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTINEOPLASTIC ACTIVITY;
ANTIPROLIFERATIVE ACTIVITY;
APOPTOSIS;
ARTICLE;
CELL CULTURE;
CELL METABOLISM;
CELL PROLIFERATION;
CONTROLLED STUDY;
DRUG SCREENING;
DRUG STABILITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELECTRON;
ELECTROPHILICITY;
HALF LIFE TIME;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
IN VIVO STUDY;
MOUSE;
NONHUMAN;
ANIMALS;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
AZO COMPOUNDS;
DRUG STABILITY;
GLUTATHIONE;
HALF-LIFE;
HUMANS;
JNK MITOGEN-ACTIVATED PROTEIN KINASES;
KINETICS;
MICE;
NEOPLASMS;
NITRIC OXIDE;
PRODRUGS;
SIGNAL TRANSDUCTION;
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EID: 84859907055
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.02.045 Document Type: Article |
Times cited : (16)
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References (7)
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