Endocrine disruptors, polychlorinated biphenyls-induced gC1qR-dependent apoptosis in human trophoblast cell line HTR-8/SVneo

Reproductive Sciences

Volumn 19, Issue 2, 2012, Pages 181-189

  Gu, Ping Qing ^a   Gao, Ling Juan ^a   Li, Li ^b   Liu, Zhu ^c   Luan, Fu Qi ^c   Peng, Yu Zhu ^a   Guo, Xi Rong ^a  

^a WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b POLYTECHNIC UNIVERSITY   (United States)

^c Clinical Laboratory   (China)

Author keywords

apoptosis; globular heads of C1q receptor (gC1qR); polychlorinated biphenyls (PCBs)

Indexed keywords

CASPASE 3; COMPLEMENT COMPONENT C1Q; GREEN FLUORESCENT PROTEIN; POLYCHLORINATED BIPHENYL; SMALL INTERFERING RNA;

ADULT; APOPTOSIS; ARTICLE; BLOOD LEVEL; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DECIDUA; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INDUCED ABORTION; MASS FRAGMENTOGRAPHY; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPONTANEOUS ABORTION; TROPHOBLAST; UPREGULATION; WESTERN BLOTTING;

ABORTION, SPONTANEOUS; ADULT; APOPTOSIS; CARRIER PROTEINS; CELL LINE; CHINA; ENDOCRINE DISRUPTORS; FEMALE; HUMANS; MITOCHONDRIAL PROTEINS; POLYCHLORINATED BIPHENYLS; PREGNANCY; PREGNANCY PROTEINS; TROPHOBLASTS;

EID: 84859899969     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111415866     Document Type: Article

References (29)

1. Vaithinathan S, Saradha B, Mathur PP. Methoxychlor induces apoptosis via mitochondria-and FasL-mediated pathways in adult rat testis. Chem Biol Interact. 2010;185(2):110-118.
2. Eskenazi B, Mocarelli P, Warner M, et al. Maternal serum dioxin level and birth outcomes in women of Seveso, Italy. Environ Health Perspect. 2003;111(7):947-953. (Pubitemid 36790391)
3. Murono EP, Derk RC, Akgul Y. In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol sidechain cleavage activity. Reprod Toxicol. 2006;21(2):148-153. (Pubitemid 43087688)
4. Martinez EM, Swartz WJ. Effects ofmethoxychlor on the reproductive system of the adult female mouse: 2. Ultrastructural observations. Reprod Toxicol. 1992;6(1):93-98.
5. Swartz WJ, Corkern M. Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies. Reprod Toxicol. 1992;6(5):431-437.
6. Wang Q, Zhao XF, Ji YL, et al. Mitochondrial signaling pathway is also involved in bisphenol A induced germ cell apoptosis in testes. Toxicol Lett. 2010;199(2):129-135.
7. Wang T, Wang Y, Fu J, et al. Characteristic accumulation and soil penetration of polychlorinated biphenyls and polybrominated diphenyl ethers in wastewater irrigated farmlands. Chemosphere. 2010;81(8):1045-1051.
8. Storelli MM, Barone G, Storelli A, Marcotrigiano GO. Levels and congener profiles of PCBs and PCDD/Fs in blue shark (Prionace glauca) liver from the South-Eastern Mediterranean Sea (Italy). Chemosphere. 2011;82(1):37-42.
9. Revich B, Aksel E, Ushakova T, et al. Dioxin exposure and public health in Chapaevsk, Russia. Chemosphere. 2001;43(4-7):951-966. (Pubitemid 32405553)
10. Kozul D, Romanic SH. Level and distribution of PCBs and organochlorine pesticides in the air, pine needles, and human milk. Arh Hig Rada Toksikol. 2010;61(3):339-356.
11. Muta T, Kang D, Kitajima S, Fujiwara T, Hamasaki N. P32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J Biol Chem. 1997;272(39): 24363-24370. (Pubitemid 27418642)
12. Rubinstein DB, Stortchevoi A, Boosalis M, et al. Receptor for the globular heads of C1q (gC1q-R; p33; Hyaluronan-binding protein is preferentially expressed by adenocarcinoma cells. Int Cancer Res. 2004;110(5):741-750. (Pubitemid 38746033)
13. Peerschke EI, Petrovan RJ, Ghebrehiwet B, Ruf W. Tissue factor pathway inhibitor-2 (TFPI-2) recognizes the complement and kininogen binding protein gC1qR/p33 (gC1qR): implications for vascular inflammation. Thromb Haemost. 2004;92(4):811-819. (Pubitemid 39386709)
14. Xu L, Xiao N, Liu F, Ren H, Gu J. Inhibition of RIG-I and MDA5- dependent antiviral response by gC1qR at mitochondria. Proc Natl Acad Sci USA. 2009;106(5):1530-1535.
15. Meenakshi J, Anupama SK, Datta K. Constitutive expression of hyaluronan binding protein 1 (HABP1/p32/gC1qR) in normal fibroblast cells perturbs its growth characteristics and induces apoptosis. Biochem Biophys Res Commun. 2003;300(3):686-693. (Pubitemid 36268891)
16. Croley TR, Hughes RJ, Koenig BG, Metcalfe CD, March RE. Mass spectrometry applied to the analysis of estrogens in the environment, Rapid Commun. Mass Spectrom. 2000;14(13): 1087-1093. (Pubitemid 30451250)
17. Small CM, Cheslack-Postava K, Terrell M, et al. Risk of spontaneous abortion among women exposed to polybrominated biphenyls. Environ Res. 2007;105(2):247-255. (Pubitemid 47368183)
18. Glaser SL, Clarke CA, Keegan TH, et al. Attenuation of social class and reproductive risk factor associations for Hodgkin lymphoma due to selection bias in controls. Cancer Causes Control. 2004;15(7):731-739. (Pubitemid 39060934)
19. Bulletti C, Flamigni C, Giacomucci E. Reproductive failure due to spontaneous abortion and recurrent miscarriage. Hum Reprod Update. 1996;2(2):118-136. (Pubitemid 26173039)
20. Law DC, Klebanoff MA, Brock JW, Dunson DB, Longnecker MP. Maternal serum levels of polychlorinated biphenyls and 1, 1-dichloro-2, 2-bis (p-chlorophenyl) ethylene (DDE) and time to pregnancy. Am J Epidemiol. 2005;162(6):523-532. (Pubitemid 41253250)
21. Axmon A, Rylander L, Strömberg U, Jönsson B, Nilsson-Ehle P, Hagmar L. Polychlorinated biphenyls in serum and time to pregnancy. Environ Res. 2004;96(2):186-195. (Pubitemid 39119796)
22. Mallick J, Datta K. HABP1/p32/gC1qR induces aberrant growth and morphology in Schizosaccharomyces pombe through its N-terminal alpha helix. Exp Cell Res. 2005;309(2):250-263. (Pubitemid 41317350)
23. Peerschke EI, Murphy TK, Ghebrehiwet B. Activation-dependent surface expression of gC1qR/p33 on human blood platelets. Thromb Haemost. 2003;89(2):331-339. (Pubitemid 36227285)
24. Peerschke EI, Ghebrehiwet B. The contribution of gC1qR/p33 in infection and inflammation. Immunobiology. 2007;212(4-5):333-342. (Pubitemid 46825239)
25. Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, Ruoslahti E. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol. 2010;30(6):1303-1318.
26. Peerschke EI, Minta JO, Zhou SZ, et al. Expression of gC1q-R/p33 and its major ligands in human atherosclerotic lesions. Mol Immunol. 2004;41(8):759-766. (Pubitemid 38953633)
27. Vandivier RW, Ogden CA, Fadok VA, et al. Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex. J Immunol. 2002;169(7):3978-3986.
28. Chowdhury AR, Ghosh I, Datta K. Excessive reactive oxygen species induces apoptosis in fibroblasts: role of mitochondrially accumulated hyaluronic acid binding protein 1 (HABP1/p32/ gC1qR). Exp Cell Res. 2008;314(3):651-667.
29. Fogal V, Zhang L, Krajewski S, Ruoslahti E. Mitochondrial/ cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res. 2008;68(17):7210-7218.