Inhibitory activities of pancreatic lipase and phosphodiesterase from Korean medicinal plant extracts

Phytotherapy Research

Volumn 26, Issue 5, 2012, Pages 778-782

  Lee, Yun Mi ^a   Kim, Young Sook ^a   Lee, Youngseop ^a   Kim, Junghyun ^a   Sun, Hang ^b   Kim, Joo Hwan ^c   Kim, Jin Sook ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^b KUNMING INSTITUTE OF BOTANY   (China)

^c Gachon University   (South Korea)

Author keywords

Korean medicinal plants; pancreatic lipase; phosphodiesterase; Sorbus commixta; Viscum album

Indexed keywords

4 NITROPHENOL; ABIES KOREANA EXTRACT; ACER TETARICUM EXTRACT; ACTINIDIA POLYGAMA EXTRACT; AGRIMONIA PILOSA EXTRACT; ANEMARRHENA ASPHODELOIDES EXTRACT; ANGELICA CAPILLARIES EXTRACT; ARTEMISIA CAPILLARIES EXTRACT; ASTER AGERATOIDES EXTRACT; ASTILBE RUBRA EXTRACT; BUTYRIC ACID 4 NITROPHENYL ESTER; CAMELLIA JAPONICA EXTRACT; CASTANEA CRENATA EXTRACT; CATALPA BIGNONIOIDES EXTRACT; CHRYSANTHEMUM INDICUM EXTRACT; METHANOL; PHENOL DERIVATIVE; PHOSPHODIESTERASE; PLANT EXTRACT; SORBUS COMMIXTA EXTRACT; STEPHANANDRA INCISA EXTRACT; TETRAHYDROLIPSTATIN; TEUCRIUM VISCIDUM EXTRACT; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIOLA TAKESIMANA EXTRACT; VISCUM ALBUM EXTRACT; VITEX ROTUNDIFOLIA EXTRACT; WEIGELA SUBSESSILIS EXTRACT; XANTHIUM STRUMARIUM EXTRACT;

ACERACEAE; ACTINIDIACEAE; ARTICLE; BIGNONIACEAE; CAPRIFOLIACEAE; COMPOSITAE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; FAGACEAE; HAEMODORACEAE; IC 50; KOREA; LABIATAE; LORANTHACEAE; MEDICINAL PLANT; NONHUMAN; OBESITY; PINACEAE; PLANT LEAF; PLANT ROOT; POWDER; PROTEIN HYDROLYSIS; ROSACEAE; SAXIFRAGACEAE; STYRACACEAE; THEACEAE; UMBELLIFERAE; VIOLACEAE;

HUMANS; INHIBITORY CONCENTRATION 50; LIPASE; OBESITY; PANCREAS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PLANTS, MEDICINAL; REPUBLIC OF KOREA; SORBUS; VISCUM ALBUM;

SORBUS COMMIXTA; VISCUM ALBUM;

EID: 84859890141     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3644     Document Type: Article

References (18)

1. Ahmed MF, Ahmed MA, Thayyil H, Zameeruddin K, Ibrahim M,. 2008. Antioxidative activity of Melia azedarach Linn leaf extract. Iran J Pharmacol Ther 7: 31-34.
2. Bae JT, Sim GS, Kim JH, Pyo HB, Yun JW, Lee BC,. 2007 Antioxidative activity of the hydrolytic enzyme treated Sorbus commixta Hedl. and its inhibitory effect on matrix metalloproteinase-1 in UV irradiated human dermal fibroblasts. Arch Pharm Res 30: 1116-1123.
3. Bray GA,. 2009. Medications for obesity: mechanisms and applications. Clin Chest Med 30: 525-538, ix.
4. Campbell ML, Mathys ML,. 2001. Pharmacologic options for the treatment of obesity. Am J Health Syst Pharm 58: 1301-1308. (Pubitemid 32656221)
5. Carek PJ, Dickerson LM,. 1999. Current concepts in the pharmacological management of obesity. Drugs 57: 883-904. (Pubitemid 29313201)
6. James PT, Rigby N, Leach R,. 2004. The obesity epidemic, metabolic syndrome and future prevention strategies. Eur J Cardiovasc Prev Rehabil 11: 3-8. (Pubitemid 38388918)
7. Kim HY, Kang MH,. 2005. Screening of Korean medicinal plants for lipase inhibitory activity. Phytother Res 19: 359-361. (Pubitemid 41098134)
8. Kim HY, Oh JH,. 1999. Screening of Korean forest plants for rat lens aldose reductase inhibition. Biosci Biotechnol Biochem 63: 184-188. (Pubitemid 129555256)
9. Kim JH, Kim HJ, Park HW, Youn SH, Choi DY, Shin CS,. 2007. Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment. FEMS Microbiol Lett 276: 93-98. (Pubitemid 47620462)
10. Kim YS, Lee YM, Kim H, et al,. 2010. Anti-obesity effect of Morus bombycis root extract: anti-lipase activity and lipolytic effect. J Ethnopharmacol 130: 621-624.
11. Lee YS, Seo KI, Shim KH,. 1999. Antimicrobial activities of chestnut flower extracts (Castanea crenata). Kor J Postharvest Sci Technol 6: 104-109.
12. Lowe ME,. 1994. Pancreatic triglyceride lipase and colipase: insights into dietary fat digestion. Gastroenterology 107: 1524-1536. (Pubitemid 24328294)
13. Lyu SY, Park WB,. 2006. Mistletoe lectin (Viscum album coloratum) modulates proliferation and cytokine expressions in murine splenocytes. J Biochem Mol Biol 39: 662-670.
14. Na M, Kim BY, Osada H, Ahn JS,. 2009. Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta. J Enzyme Inhib Med Chem 24: 1056-1059.
15. Onodera K, Hanashiro K, Yasumoto T,. 2006. Camellianoside, a novel antioxidant glycoside from the leaves of Camellia japonica. Biosci Biotechnol Biochem 70: 1995-1998. (Pubitemid 44285440)
16. Rahimi R, Ghiasi S, Azimi H, Fakhari S, Abdollahi M,. 2010. A review of the herbal phosphodiesterase inhibitors; future perspective of new drugs. Cytokine 49: 123-129.
17. Sato Y, Akao T, He JX, et al,. 2006. Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3. J Ethnopharmacol 105: 409-414.
18. Sharma N, Sharma VK, Seo SY,. 2005. Screening of some medicinal plants for anti-lipase activity. J Ethnopharmacol 97: 453 - 456. (Pubitemid 40312318)