Treatment of endometriosis in different ethnic populations: a meta-analysis of two clinical trials

BMC Women's Health

Volumn 12, Issue , 2012, Pages

  Gerlinger, Christoph ^a   Faustmann, Thomas ^a   Hassall, Jeffrey J ^b   Seitz, Christian ^a  

^a BAYER PHARMA AG   (Germany)

^b South East Asia University   (Singapore)

Author keywords

Dienogest; Endometriosis; Ethnic differences; Europe Japan; GnRH analogue; Progestogen progestin

Indexed keywords

BUSERELIN ACETATE; DIENOGEST; GONADORELIN; LEUPRORELIN;

ADULT; ARTICLE; BONE DENSITY; DRUG EFFICACY; ENDOMETRIOSIS; ETHNIC AND RACIAL GROUPS; ETHNIC DIFFERENCE; EUROPEAN AMERICAN; FEMALE; HUMAN; JAPANESE; LITERATURE; MAJOR CLINICAL STUDY; PHYSIOLOGY; POPULATION RESEARCH; VISUAL ANALOG SCALE;

ASIAN CONTINENTAL ANCESTRY GROUP; BUSERELIN; ENDOMETRIOSIS; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HORMONE ANTAGONISTS; HUMANS; JAPAN; LEUPROLIDE; NANDROLONE; TREATMENT OUTCOME;

EID: 84859861620     PISSN: None     EISSN: 14726874     Source Type: Journal    
DOI: 10.1186/1472-6874-12-9     Document Type: Article

References (54)

1. Giudice LC. Endometriosis. N Engl J Med 2010, 362:2389-2398. 10.1056/NEJMcp1000274, 3108065, 20573927.
2. Kennedy S, Bergqvist A, Chapron C, D'Hooghe T, Dunselman G, Greb R, et al. ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 2005, 20:2698-2704. 10.1093/humrep/dei135, 15980014.
3. Eskenazi B, Warner ML. Epidemiology of endometriosis. Obstet Gynecol Clin North Am 1997, 24:235-258. 10.1016/S0889-8545(05)70302-8, 9163765.
4. Arumugam K, Templeton AA. Endometriosis and race. Aust N Z J Obstet Gynaecol 1992, 32:164-165. 10.1111/j.1479-828X.1992.tb01932.x, 1520204.
5. Cramer DW, Missmer SA. The epidemiology of endometriosis. Ann N Y Acad Sci 2002, 955:11-22. 10.1111/j.1749-6632.2002.tb02761.x, 11949940.
6. Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ. Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol 2004, 160:784-796. 10.1093/aje/kwh275, 15466501.
7. Sangi-Haghpeykar H, Poindexter AN. Epidemiology of endometriosis among parous women. Obstet Gynecol 1995, 85:983-992. 10.1016/0029-7844(95)00074-2, 7770271.
8. Montgomery GW, Nyholt DR, Zhao ZZ, Treloar SA, Painter JN, Missmer SA, et al. The search for genes contributing to endometriosis risk. Hum Reprod Update 2008, 14:447-457. 10.1093/humupd/dmn016, 2574950,2574950, 18535005.
9. Kvaskoff M, Bijon A, Mesrine S, Clavel-Chapelon F, Boutron-Ruault MC. Pigmentary traits and risk of endometriosis. Hum Reprod 2010, 25:3157-3158. 10.1093/humrep/deq250, 20884667.
10. Osteen KG, Bruner-Tran KL, Eisenberg E. Reduced progesterone action during endometrial maturation: A potential risk factor for the development of endometriosis [abstract]. Fertil Steril 2005, 83:529-537. 10.1016/j.fertnstert.2004.11.026, 15749474.
11. Trabert B, Peters U, De Roos AJ, Scholes D, Holt VL. Diet and risk of endometriosis in a population-based case-control study. Br J Nutr 2011, 105:459-467. 10.1017/S0007114510003661, 3374872, 20875189.
12. Trabert B, De Roos AJ, Schwartz SM, Peters U, Scholes D, Barr DB, et al. Non-dioxin-like polychlorinated biphenyls and risk of endometriosis. Environ Health Perspect 2010, 118:1280-1285. 10.1289/ehp.0901444, 2944090, 20423815.
13. Oehmke F, Weyand J, Hackethal A, Konrad L, Omwandho C, Tinneberg HR. Impact of endometriosis on quality of life: a pilot study. Gynecol Endocrinol 2009, 25:722-725. 10.3109/09513590903159607, 19903050.
14. Sepulcri RP. do Amaral VF. Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis. Eur J Obstet Gynecol Reprod Biol 2009, 142:53-56. 10.1016/j.ejogrb.2008.09.003, 19010584.
15. Tripoli TM, Sato H, Sartori MG, Fernando DA, Girao MJ, Schor E. Evaluation of quality of life and sexual satisfaction in women suffering from chronic pelvic pain with or without endometriosis. J Sex Med 2011, 8:497-503. 10.1111/j.1743-6109.2010.01976.x, 20722779.
16. endometriosis.org [Internet] Japan Endometriosis Association publishes third national study: endometriosis.org news archive [updated 15 April 2007; cited 20 June 2011].Available from: http://endometriosis.org/news/support-awareness/japan-endometriosis-association-announces-significantly-adverse-effects-of-gnrh-use/, endometriosis.org [Internet].
17. Irahara M, Tetsufumi Y, Masahiko M. Treatment of endometriosis with dienogest - efficacy and countermeasures for adverse drug reactions. Prog Med 2008, 28:1749-1756.
18. Selak V, Farquhar C, Prentice A, Singla A. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst Rev 2007, 4:CD000068.
19. Sitruk-Ware R. Pharmacological profile of progestins. Maturitas 2004, 47:277-283. 10.1016/j.maturitas.2004.01.001, 15063480.
20. Sitruk-Ware R. New progestagens for contraceptive use. Hum Reprod Update 2006, 12:169-178.
21. Kuhl H. Comparative pharmacology of newer progestogens. Drugs 1996, 51:188-215.
22. Yasuda SU, Zhang L, Huang SM. The role of ethnicity in variability in response to drugs: focus on clinical pharmacology studies. Clin Pharmacol Ther 2008, 84:417-423. 10.1038/clpt.2008.141, 18615002.
23. Strowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C. Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Hum Reprod 2010, 25:633-641. 10.1093/humrep/dep469, 20089522.
24. Harada T, Momoeda M, Taketani Y, Aso T, Fukunaga M, Hagino H, et al. Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis - a randomized, double-blind, multicenter, controlled trial. Fertil Steril 2009, 91:675-681. 10.1016/j.fertnstert.2007.12.080, 18653184.
25. Sagsveen M, Farmer JE, Prentice A, Breeze A. Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density. Cochrane Database Syst Rev 2003, 4:CD001297.
26. Sasagawa S, Shimizu Y, Kami H, Takeuchi T, Mita S, Imada K, et al. Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile. Steroids 2008, 73:222-231. 10.1016/j.steroids.2007.10.003, 18061638.
27. Köhler G, Faustmann TA, Gerlinger C, Seitz C, Mueck AO. A dose-ranging study to determine the efficacy and safety of 1, 2, and 4 mg of dienogest daily for endometriosis. Int J Gynaecol Obstet 2010, 108:21-25. 10.1016/j.ijgo.2009.08.020, 19819448.
28. Strowitzki T, Faustmann T, Gerlinger C, Seitz C. Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol 2010, 151:193-198. 10.1016/j.ejogrb.2010.04.002, 20444534.
29. Momoeda M, Harada T, Terakawa N, Aso T, Fukunaga M, Hagino H, et al. Long-term use of dienogest for the treatment of endometriosis. J Obstet Gynaecol Res 2009, 35:1069-1076. 10.1111/j.1447-0756.2009.01076.x, 20025633.
30. Petraglia F, Hornung D, Seitz C, Faustmann T, Gerlinger C, Luisi S, et al. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment. Arch Gynecol Obstet 2011, 285(1):167-73. 3249203, 21681516.
31. Katayama H, Katayama T, Uematsu K, Hiratsuka M, Kiyomura M, Shimizu Y, et al. Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model. Hum Reprod 2010, 25:2851-2858. 10.1093/humrep/deq241, 20813806.
32. Mueck AO. Dienogest: an oral progestogen for the treatment of endometriosis. Expert Rev Obstet Gynecol 2010, 6:5-15.
33. Katsuki Y, Sasagawa S, Takano Y, Shibutani Y, Aoki D, Udagawa Y, et al. Animal studies on the endocrinological profile of dienogest, a novel synthetic steroid. Drugs Exp Clin Res 1997, 23:45-62.
34. Kitawaki J, Kusuki I, Yamanaka K, Suganuma I. Maintenance therapy with dienogest following gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain. Eur J Obstet Gynecol Reprod Biol 2011, Epub ahead of print.
35. Ichigo S, Takagi H, Matsunami K, Suzuki N, Imai A. Beneficial effects of dienogest on uterine myoma volume: a retrospective controlled study comparing with gonadotropin-releasing hormone agonist. Arch Gynecol Obstet 2011, 284(3):667-70. 10.1007/s00404-010-1732-6, 21052701.
36. McCormack PL. Dienogest: a review of its use in the treatment of endometriosis. Drugs 2010, 70:2073-2088. 10.2165/11206320-000000000-00000, 20964453.
37. Kitawaki J. Maintenance therapy for endometriosis. Nippon Rinsho 2010, 68:163-167.
38. Schindler AE, Christensen B, Henkel A, Oettel M, Moore C. High-dose pilot study with the novel progestogen dienogestin patients with endometriosis. Gynecol Endocrinol 2006, 22:9-17. 10.1080/09513590500431482, 16522528.
39. Cosson M, Querleu D, Donnez J, Madelenat P, Konincks P, Audebert A, et al. Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery: results of a prospective, multicenter, randomized study. Fertil Steril 2002, 77:684-692. 10.1016/S0015-0282(01)03270-8, 11937116.
40. Kozielski J, Kamiński K, Fiegler P, Gabryś J. Endometriosis of the lungs: analysis of diagnosis and therapy. Ginekol Pol 2001, 72:305-307.
41. Kamiński K, Fiegler P, Marr J, Moore C. Treatment of endometriosis with dienogest: preliminary report. Ginekol Pol 2001, 72:299-304.
42. Katsuki Y, Takano Y, Futamura Y, Shibutani Y, Aoki D, Udagawa Y, et al. Effects of dienogest, a synthetic steroid, on experimental endometriosis in rats. Eur J Endocrinol 1998, 138:216-226. 10.1530/eje.0.1380216, 9506869.
43. Gerlinger C, Schumacher U, Faustmann T, Colligs A, Schmitz H, Seitz C. Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials. Health Qual Life Outcomes 2010, 8:138. 10.1186/1477-7525-8-138, 3002916, 21106059.
44. Bergqvist A, Hummelshoj L, Haergerstam G, Ogeus B, Mills DS, Blomberg S, et al. Enhancing quality of life in women and girls with endometriosis-related pain when traditional treatments have failed [Internet]. European Society of Human Reproduction and Embryology (ESHRE); Special interest Group for endometriosis and endometrium [updated 11-12 July 2000; cited 20 June 2011].Available from: http://www.eshre.eu/01/default.aspx?pageid=244.
45. Whitehead A. Meta-Analysis of Controlled Clinical Trials 2002, John Wiley & Sons Inc, Chichester.
46. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003, 327:557-560. 10.1136/bmj.327.7414.557, 192859, 12958120.
47. Institute for Statistics and Mathematics The R Project for Statistical Computing. Vienna University of Economics and Business [2010] [cited 20 June 2011].Available from: http://www.r-project.org/, Institute for Statistics and Mathematics.
48. Schwarzer G. An R package for meta-analysis. R News 2007, 7:40-45.
49. Finkelstein JS, Lee ML, Sowers MF, Ettinger B, Neer RM, Kelsey JL, et al. Ethnic variation in bone density in premenopausal and early perimenopausal women: effects of anthropometric and lifestyle factors. J Clin Endocrinol Metab 2002, 87:3057-3067. 10.1210/jc.87.7.3057, 12107201.
50. Hill P, Wynder EL, Helman P, Hickman R, Rona G, Kuno K. Plasma hormone levels in different ethnic populations of women. Cancer Res 1976, 36(Part 1):2297-2301.
51. Seeman E. Estrogen, androgen, and the pathogenesis of bone fragility in women and men. Curr Osteoporos Rep 2004, 2:90-96. 10.1007/s11914-004-0016-0, 16036088.
52. Popat VB, Calis KA, Vanderhoof VH, Cizza G, Reynolds JC, Sebring N, et al. Bone mineral density in estrogen-deficient young women. J Clin Endocrinol Metab 2009, 94:2277-2283. 10.1210/jc.2008-1878, 2708959, 19401379.
53. Crosignani PG, De Cecco L, Gastaldi A, Venturini PL, Oldani S, Vegetti W, et al. Leuprolide in a 3-monthly versus a monthly depot formulation for the treatment of symptomatic endometriosis: a pilot study. Hum Reprod 1996, 11:2732-2735. 10.1093/oxfordjournals.humrep.a019199, 9021380.
54. Fukushima M, Shindo M, Sato K. Hormone treatment related bone mineral content changes in Japanese women with endometriosis. Asia Oceania J Obstet Gynaecol 1993, 19:299-307.