3β-hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species

Journal of Bone and Mineral Metabolism

Volumn 30, Issue 2, 2012, Pages 144-153

  Mirza, Rusella ^a,b   Qiao, Shanlou ^a   Tateyama, Keisuke ^a   Miyamoto, Takeshi ^c   Xiuli, Lu ^d   Seo, Hisao ^a  

^a CHUBU UNIVERSITY   (Japan)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d LIAONING UNIVERSITY   (China)

Author keywords

Bone; Chondrocyte; DHCR24; ROS (reactive oxygen species)

Indexed keywords

ALKALINE PHOSPHATASE; MATRIX METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE; SONIC HEDGEHOG PROTEIN;

3BETA HYDROXYSTEROL DELTA24 REDUCTASE GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL DISRUPTION; CELL ENLARGEMENT; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; ENZYME SYNTHESIS; GENE; GENE EXPRESSION; GENE FUNCTION; GROWTH PLATE; LONG BONE; METATARSAL BONE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACETYLCYSTEINE; ANDROSTENES; ANIMALS; BIOLOGICAL MARKERS; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CHONDROCYTES; CYTOPROTECTION; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; INSULIN; METATARSAL BONES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TISSUE CULTURE TECHNIQUES;

EID: 84859853125     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-011-0303-7     Document Type: Article

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