Integrative responses of neurons in parabrachial nuclei to a nauseogenic gastrointestinal stimulus and vestibular stimulation in vertical planes

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 302, Issue 8, 2012, Pages

  Suzuki, Takeshi ^a   Sugiyama, Yoichiro ^a   Yates, Bill J ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Motion sickness; Nausea; Otolith organ; Semicircular canal; Vomiting

Indexed keywords

COPPER SULFATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY MOVEMENT; CENTRAL INTERMEDIATE SUBSTANCE; GASTROINTESTINAL TRACT; MOTION SICKNESS; NONHUMAN; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; VESTIBULAR STIMULATION; VOMITING;

ANIMALS; CATS; FEMALE; MALE; MOTION SICKNESS; NAUSEA; NEURONS; ORIENTATION; OTOLITHIC MEMBRANE; PONS; SEMICIRCULAR CANALS; VISCERAL AFFERENTS;

EID: 84859762850     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00680.2011     Document Type: Article

References (61)

1. Ariumi H, Saito R, Nago S, Hyakusoku M, Takano Y, Kamiya H. The role of tachykinin NK-1 receptors in the area postrema of ferrets in emesis. Neurosci Lett 286: 123-126, 2000.
2. Baird JP, Travers SP, Travers JB. Integration of gastric distension and gustatory responses in the parabrachial nucleus. Am J Physiol Regul Integr Comp Physiol 281: R1581-R1593, 2001.
3. Balaban CD. Vestibular nucleus projections to the parabrachial nucleus in rabbits: Implications for vestibular influences on the autonomic nervous system. Exp Brain Res 108: 367-381, 1996.
4. Balaban CD, Jacob RG, Furman JM. Neurologic bases for comorbidity of balance disorders, anxiety disorders and migraine: Neurotherapeutic implications. Expert Rev Neurother 11: 379-394, 2011.
5. Balaban CD, McGee DM, Zhou J, Scudder CA. Responses of primate caudal parabrachial nucleus and Kolliker-Fuse nucleus neurons to whole body rotation. J Neurophysiol 88: 3175-3193, 2002.
6. Berkley KJ, Scofield SL. Relays from the spinal cord and solitary nucleus through the parabrachial nucleus to the forebrain in the cat. Brain Res 529: 333-338, 1990.
7. Berman AI. The Brain Stem of the Cat. Madison, WI: University of Wisconsin Press, 1968.
8. Bountra C, Bunce K, Dale T, Gardner C, Jordan C, Twissell D, Ward P. Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets. Eur J Pharmacol 249: R3-R4, 1993.
9. Brizzee KR, Marshall KR. Developmental studies on emetic response to tartar emetic and copper sulfate in the cat. Proc Soc Exp Biol Med 103: 839-842, 1960.
10. Cechetto DF. Central representation of visceral function. Fed Proc 46: 17-23, 1987.
11. Cechetto DF, Calaresu FR. Central pathways relaying cardiovascular afferent information to amygdala. Am J Physiol Regul Integr Comp Physiol 248: R38-R45, 1985.
12. Cechetto DF, Ciriello J, Calaresu FR. Afferent connections to cardiovascular sites in the amygdala: A horseradish peroxidase study in the cat. J Auton Nerv Syst 8: 97-110, 1983.
13. Cho YK, Li CS. Gustatory neural circuitry in the hamster brain stem. J Neurophysiol 100: 1007-1019, 2008.
14. Cohen MI, Shaw CF. Role in the inspiratory off-switch of vagal inputs to rostral pontine inspiratory-modulated neurons. Respir Physiol Neurobiol 143: 127-140, 2004.
15. De Jonghe BC, Horn CC. Chemotherapy agent cisplatin induces 48 h fos expression in the brain of a vomiting species, the house musk shrew (Suncus murinus). Am J Physiol Regul Integr Comp Physiol 296: R902-R911, 2009.
16. Destefino VJ, Reighard DA, Sugiyama Y, Suzuki T, Cotter LA, Larson MG, Gandhi NJ, Barman SM, Yates BJ. Responses of neurons in the rostral ventrolateral medulla (RVLM) to whole-body rotations: Comparisons in decerebrate and conscious cats. J Appl Physiol 110: 1699-1707, 2011.
17. Di Lorenzo PM. Corticofugal influence on taste responses in the parabrachial pons of the rat. Brain Res 530: 73-84, 1990.
18. Endo T, Nemoto M, Minami M, Yoshioka M, Saito H, Parvez SH. Changes in the afferent abdominal vagal nerve activity induced by cisplatin and copper sulfate in the ferret. Biog Amine 11: 399-407, 1995.
19. Ezure K, Tanaka I, Miyazaki M. Pontine projections of pulmonary slowly adapting receptor relay neurons in the cat. NeuroReport 9: 411-414, 1998.
20. Feldman JL. Neurophysiology of breathing in mammals. In: Handbook of Physiology. The Nervous System. IV. Intrinsic Regulatory Systems of the Brain, edited by Bloom FE. Bethesda, MD: American Physiological Society, 1986, p. 463-524.
21. Fulwiler CE, Saper CB. Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Res 319: 229-259, 1984.
22. Gardner CJ, Armour DR, Beattie DT, Gale JD, Hawcock AB, Kilpatrick GJ, Twissell DJ, Ward P. GR205171: A novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept 65: 45-53, 1996.
23. Geran LC, Travers SP. Bitter-responsive gustatory neurons in the rat parabrachial nucleus. J Neurophysiol 101: 1598-1612, 2009.
24. Gonsalves S, Watson J, Ashton C. Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets. Eur J Pharmacol 305: 181-185, 1996.
25. Granata AR. Ascending and descending convergent inputs to neurons in the nucleus parabrachialis of the rat: An intracellular study. Brain Res 600: 315-321, 1993.
26. Green AM, Angelaki DE. Internal models and neural computation in the vestibular system. Exp Brain Res 200: 197-222, 2010.
27. Han ZS, Gu GB, Sun CQ, Ju G. Convergence of somatosensory and baroreceptive inputs onto parabrachio-subfornical organ neurons in the rat: An electrophysiological study. Brain Res 566: 239-247, 1991.
28. Herbert H, Moga MM, Saper CB. Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol 293: 540-580, 1990.
29. Horn CC, De Jonghe BC, Matyas K, Norgren R. Chemotherapyinduced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat. Am J Physiol Regul Integr Comp Physiol 297: R1375-R1382, 2009.
30. Jhamandas JH, Aippersbach SE, Harris KH. Cardiovascular influences on rat parabrachial nucleus: An electrophysiological study. Am J Physiol Regul Integr Comp Physiol 260: R225-R231, 1991.
31. Jhamandas JH, Harris KH. Influence of nucleus tractus solitaries stimulation and baroreceptor activation on rat parabrachial neurons. Brain Res Bull 28: 565-571, 1992.
32. Jian BJ, Shintani T, Emanuel BA, Yates BJ. Convergence of limb, visceral, and vertical semicircular canal or otolith inputs onto vestibular nucleus neurons. Exp Brain Res 144: 247-257, 2002.
33. King GW. Topology of ascending brainstem projections to nucleus parabrachialis in the cat. J Comp Neurol 191: 615-638, 1980.
34. Kobashi M, Adachi A. Projection of nucleus tractus solitarius units influenced by hepatoportal afferent signal to parabrachial nucleus. J Auton Nerv Syst 16: 153-158, 1986.
35. Lang IM, Medda BK, Shaker R. Differential activation of pontomedullary nuclei by acid perfusion of different regions of the esophagus. Brain Res 1352: 94-107, 2010.
36. Lang IM, Sarna SK, Shaker R. Gastrointestinal motor and myoelectric correlates of motion sickness. Am J Physiol Gastrointest Liver Physiol 277: G642-G652, 1999.
37. Leslie RA, Gwyn DG. Neuronal connections of the area postrema. Fed Proc 43: 2941-2943, 1984.
38. Lipski J, Ezure K, Wong She RB. Identification of neurons receiving input from pulmonary rapidly adapting receptors in the cat. J Physiol 443: 55-77, 1991.
39. McCall AA, Yates BJ. Compensation following bilateral vestibular damage. Front Neurol 2: 88, 2011.
40. McCandless CH, Balaban CD. Parabrachial nucleus neuronal responses to off-vertical axis rotation in macaques. Exp Brain Res 202: 271-290, 2010.
41. Miller AD, Nonaka S, Jakus J. Brain areas essential or non-essential for emesis. Brain Res 647: 255-264, 1994.
42. Miller DM, Cotter LA, Gandhi NJ, Schor RH, Cass SP, Huff NO, Raj SG, Shulman JA, Yates BJ. Responses of caudal vestibular nucleus neurons of conscious cats to rotations in vertical planes, before and after a bilateral vestibular neurectomy. Exp Brain Res 188: 175-186, 2008.
43. Miller DM, Cotter LA, Gandhi NJ, Schor RH, Huff NO, Raj SG, Shulman JA, Yates BJ. Responses of rostral fastigial nucleus neurons of conscious cats to rotations in vertical planes. Neuroscience 155: 317-325, 2008.
44. Mungarndee SS, Lundy RF Jr, Norgren R. Central gustatory lesions and learned taste aversions: Unconditioned stimuli. Physiol Behav 87: 542-551, 2006.
45. Otake K, Ezure K, Lipski J, Wong She RB. Projections from the commissural subnucleus of the nucleus of the solitary tract: An anterograde tracing study in the cat. J Comp Neurol 324: 365-378, 1992.
46. Papas S, Ferguson AV. Electrophysiological characterization of reciprocal connections between the parabrachial nucleus and the area postrema in the rat. Brain Res Bull 24: 577-582, 1990.
47. Porter JD, Balaban CD. Connections between the vestibular nuclei and brain stem regions that mediate autonomic function in the rat. J Vestib Res 7: 63-76, 1997.
48. Reilly S, Trifunovic R. Lateral parabrachial nucleus lesions in the rat: Neophobia and conditioned taste aversion. Brain Res Bull 55: 359-366, 2001.
49. Schor RH, Miller AD, Tomko DL. Responses to head tilt in cat central vestibular neurons. I. Direction of maximum sensitivity. J Neurophysiol 51: 136-146, 1984.
50. Spector AC. Gustatory function in the parabrachial nuclei: Implications from lesion studies in rats. Rev Neurosci 6: 143-175, 1995.
51. Spector AC. Gustatory parabrachial lesions disrupt taste-guided quinine responsiveness in rats. Behav Neurosci 109: 79-90, 1995.
52. Sugiyama Y, Suzuki T, Destefino VJ, Yates BJ. Integrative responses of neurons in nucleus tractus solitarius to visceral afferent stimulation and vestibular stimulation in vertical planes. Am J Physiol Regul Integr Comp Physiol 301: R1380-R1390, 2011.
53. Takeuchi Y, McLean JH, Hopkins DA. Reciprocal connections between the amygdala and parabrachial nuclei: Ultrastructural demonstration by degeneration and axonal transport of horseradish peroxidase in the cat. Brain Res 239: 583-588, 1982.
54. Verbalis JG, Richardson DW, Stricker EM. Vasopressin release in response to nausea-producing agents and cholecystokinin in monkeys. Am J Physiol Regul Integr Comp Physiol 252: R749-R753, 1987.
55. Wang SC, Borison HL. Copper sulphate emesis; a study of afferent pathways from the gastrointestinal tract. Am J Physiol 164: 520-526, 1951.
56. Williams JB, Murphy DM, Reynolds KE, Welch SJ, King MS. Demonstration of a bilateral projection from the rostral nucleus of the solitary tract to the medial parabrachial nucleus in rat. Brain Res 737: 231-237, 1996.
57. Yamamoto T. Neural mechanisms of taste aversion learning. Neurosci Res 16: 181-185, 1993.
58. Yamamoto T, Fujimoto Y, Shimura T, Sakai N. Conditioned taste aversion in rats with excitotoxic brain lesions. Neurosci Res 22: 31-49, 1995.
59. Yates BJ, Jian BJ, Cotter LA, Cass SP. Responses of vestibular nucleus neurons to tilt following chronic bilateral removal of vestibular inputs. Exp Brain Res 130: 151-158, 2000.
60. Yuan CS, Barber WD. Parabrachial nucleus: Neuronal evoked responses to gastric vagal and greater splanchnic nerve stimulation. Brain Res Bull 27: 797-803, 1991.
61. Zimnicka AM, Ivy K, Kaplan JH. Acquisition of dietary copper: A role for anion transporters in intestinal apical copper uptake. Am J Physiol Cell Physiol 300: C588-C599, 2011.