Analysis of a genome-wide association study-linked locus (CCR6) in Asian rheumatoid arthritis

DNA and Cell Biology

Volumn 31, Issue 4, 2012, Pages 607-610

  Teng, Esther ^a   Leong, Khai Pang ^b   Li, Hui Hua ^a   Thong, Bernard ^b   Koh, Ee Tzun ^b   Loi, Pooi Ling ^a   Zhao, Yi ^a   Tan, Eng King ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b TAN TOCK SENG HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR6;

ADULT; ALLELE; ARTICLE; ASIAN; CASE CONTROL STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SEX RATIO;

ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; LOGISTIC MODELS; MALE; MODELS, GENETIC; ODDS RATIO; RECEPTORS, CCR6; RISK FACTORS; SEX FACTORS;

EID: 84859756829     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1350     Document Type: Article

References (13)

1. Ai, L.S., and Liao, F. (2002). Mutating the four extracellular cysteines in the chemokine receptor CCR6 reveals their differing roles in receptor trafficking, ligand binding, and signaling. Biochemistry 41, 8332-8341.
2. Alamanos, Y., Voulgari, P.V., and Drosos, A.A. (2006). Incidence and prevalence of rheumatoid arthritis based on the 1987 American College of Rheumatology criteria: a systematic review. Semin Arthritis Rheum 36, 182-188.
3. Arnett, F.C., Edworthy, S.M., Bloch, D.A., et al. (1988). The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31, 315-324.
4. Bagos, P.G., and Nikolopoulos, G.K. (2007). A method for metaanalysis of case-control genetic association studies using logistic regression. Stat Appl Genet Mol Biol 6, Article17.
5. Joanna, J.Z., and Andrew, P.M. (2009). Assessment of sexspecific effects in a genome-wide association study of rheumatoid arthritis. BMC Proc 3 Suppl 7, S90.
6. Klareskog, L., Catrina, A.I., and Paget, S. (2009). Rheumatoid arthritis. Lancet 373, 659-672.
7. Kochi, Y., Okada, Y., Suzuki, A., et al. (2010). A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet 42(6), 515-519.
8. MacGregor, A.J., Snieder, H., Rigby, A.S., et al. (2000). Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 43, 30-37.
9. Nanki, T., Takada, K., Komano, Y., et al. (2009). Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis. Arthritis Res Ther 11, R149.
10. Ober, C., Loisel, D.A., and Gilad, Y. (2008). Sex-specific genetic architecture of human disease. Nat Rev Genet 9, 911-922.
11. Raychaudhuri, S., Remmers, E.F., Lee, A.T., et al. (2008). Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet 40, 1216-1223.
12. Silman, A.J., and Pearson, J.E. (2002). Epidemiology and genetics of rheumatoid arthritis. Arthritis Res 4(Suppl 3), S265-S227.
13. Stahl, E.A., Raychaudhuri, S., Remmers, E.F., et al. (2010). Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 42, 508-514.