The hydroalcoholic extract of Cassia alata (Linn.) leaves and its major compound rhein exhibits antiallergic activity via mast cell stabilization and lipoxygenase inhibition

Journal of Ethnopharmacology

Volumn 141, Issue 1, 2012, Pages 469-473

  Singh, Baljinder ^a,d   Nadkarni, Janhavi R ^b   Vishwakarma, Ram A ^a   Bharate, Sandip B ^a   Nivsarkar, Manish ^c   Anandjiwala, Sheetal ^d  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b Padmashree Dr DY Patil Institute of Biotechnology and Bioinformatics   (India)

^c B V PATEL PHARMACEUTICAL EDUCATION AND RESEARCH DEVELOPMENT PERD CENTRE   (India)

^d NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER AHMEDABAD   (India)

Author keywords

Antiallergic; Asthma; Cassia alata; HPTLC; Lipoxygenase; Mast cells

Indexed keywords

KAEMPFEROL; LIPOXYGENASE; PLANT EXTRACT; RHEIN; SENNA ALATA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIALLERGIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DRUG ACTIVITY; DRUG POTENCY; ENZYME INHIBITION; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL DEGRANULATION; NONHUMAN; PLANT LEAF; RAT; SENNA ALATA;

ANIMALS; ANTHRAQUINONES; ANTI-ALLERGIC AGENTS; CASSIA; CELL DEGRANULATION; CHROMATOGRAPHY, THIN LAYER; DENSITOMETRY; KAEMPFEROLS; LIPOXYGENASE INHIBITORS; MALE; MAST CELLS; METHANOL; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; SHEEP; SOLVENTS;

CAESALPINIOIDEAE; RATTUS; SENNA ALATA;

EID: 84859746769     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.03.012     Document Type: Article

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