VDAC blockage by phosphorothioate oligonucleotides and its implication in apoptosis

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 6, 2012, Pages 1555-1561

  Tan, Wenzhi ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptosis; G3139; Mitochondria; Oligonucleotide; Phosphorothioate; VDAC

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYTOCHROME C; CYTOTOXIC AGENT; OBLIMERSEN; OLIGONUCLEOTIDE; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; PHOSPHOROTHIOIC ACID; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; VOLTAGE DEPENDENT ANION CHANNEL; VOLTAGE DEPENDENT ANION CHANNEL 1;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; CALCIUM TRANSPORT; CHANNEL GATING; CHRONIC LYMPHATIC LEUKEMIA; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CYTOSOL; DOWN REGULATION; DRUG BINDING SITE; HUMAN; LUNG NON SMALL CELL CANCER; MELANOMA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL OUTER MEMBRANE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW;

ANIMALS; APOPTOSIS; HUMANS; ION CHANNEL GATING; MITOCHONDRIA; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84859742112     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.12.032     Document Type: Review

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