-
1
-
-
19944427292
-
Genetic basis for individual variations in pain perception and the development of a chronic pain condition
-
Diatchenko L, Slade GD, Nackley AG, Bhalang K, Sigurdsson A, Belfer I, Goldman D, Xu K, Shabalina SA, Shagin D, et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet 2005, 14:135-143.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 135-143
-
-
Diatchenko, L.1
Slade, G.D.2
Nackley, A.G.3
Bhalang, K.4
Sigurdsson, A.5
Belfer, I.6
Goldman, D.7
Xu, K.8
Shabalina, S.A.9
Shagin, D.10
-
2
-
-
33847616664
-
Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors
-
10.1016/j.pain.2006.09.022, 1905861, 17084978
-
Nackley AG, Tan KS, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain 2007, 128:199-208. 10.1016/j.pain.2006.09.022, 1905861, 17084978.
-
(2007)
Pain
, vol.128
, pp. 199-208
-
-
Nackley, A.G.1
Tan, K.S.2
Fecho, K.3
Flood, P.4
Diatchenko, L.5
Maixner, W.6
-
3
-
-
78349238506
-
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice
-
10.1111/j.1601-183X.2010.00633.x, 2975805, 20659173
-
Segall SK, Nackley AG, Diatchenko L, Lariviere WR, Lu X, Marron JS, Grabowski-Boase L, Walker JR, Slade G, Gauthier J, et al. Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice. Genes Brain Behav 2010, 9:933-946. 10.1111/j.1601-183X.2010.00633.x, 2975805, 20659173.
-
(2010)
Genes Brain Behav
, vol.9
, pp. 933-946
-
-
Segall, S.K.1
Nackley, A.G.2
Diatchenko, L.3
Lariviere, W.R.4
Lu, X.5
Marron, J.S.6
Grabowski-Boase, L.7
Walker, J.R.8
Slade, G.9
Gauthier, J.10
-
4
-
-
33845899137
-
Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure
-
10.1126/science.1131262, 17185601
-
Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS, Maixner W, Diatchenko L. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 2006, 314:1930-1933. 10.1126/science.1131262, 17185601.
-
(2006)
Science
, vol.314
, pp. 1930-1933
-
-
Nackley, A.G.1
Shabalina, S.A.2
Tchivileva, I.E.3
Satterfield, K.4
Korchynskyi, O.5
Makarov, S.S.6
Maixner, W.7
Diatchenko, L.8
-
5
-
-
0025772611
-
The role of serotonin in analgesia elicited by morphine in the periaqueductal gray matter (PAG)
-
10.1016/0006-8993(91)90849-Q, 1681985
-
Schul R, Frenk H. The role of serotonin in analgesia elicited by morphine in the periaqueductal gray matter (PAG). Brain Res 1991, 553:353-357. 10.1016/0006-8993(91)90849-Q, 1681985.
-
(1991)
Brain Res
, vol.553
, pp. 353-357
-
-
Schul, R.1
Frenk, H.2
-
6
-
-
0021707631
-
5-Hydroxytryptamine and antinociception
-
10.1016/0028-3908(84)90097-2, 6098854
-
Roberts MH. 5-Hydroxytryptamine and antinociception. Neuropharmacology 1984, 23:1529-1536. 10.1016/0028-3908(84)90097-2, 6098854.
-
(1984)
Neuropharmacology
, vol.23
, pp. 1529-1536
-
-
Roberts, M.H.1
-
7
-
-
0026603026
-
Serotonin is a directly-acting hyperalgesic agent in the rat
-
10.1016/0306-4522(92)90508-Y, 1534874
-
Taiwo YO, Levine JD. Serotonin is a directly-acting hyperalgesic agent in the rat. Neuroscience 1992, 48:485-490. 10.1016/0306-4522(92)90508-Y, 1534874.
-
(1992)
Neuroscience
, vol.48
, pp. 485-490
-
-
Taiwo, Y.O.1
Levine, J.D.2
-
8
-
-
0026534030
-
Receptor mediation of 5-HT-induced inflammation and nociception in rats
-
10.1016/0091-3057(92)90058-N, 1531705
-
Sufka KJ, Schomburg FM, Giordano J. Receptor mediation of 5-HT-induced inflammation and nociception in rats. Pharmacol Biochem Behav 1992, 41:53-56. 10.1016/0091-3057(92)90058-N, 1531705.
-
(1992)
Pharmacol Biochem Behav
, vol.41
, pp. 53-56
-
-
Sufka, K.J.1
Schomburg, F.M.2
Giordano, J.3
-
9
-
-
79251562487
-
Serotonin receptor 5-HT2B mediates serotonin-induced mechanical hyperalgesia
-
10.1523/JNEUROSCI.4682-10.2011, 21273425
-
Lin SY, Chang WJ, Lin CS, Huang CY, Wang HF, Sun WH. Serotonin receptor 5-HT2B mediates serotonin-induced mechanical hyperalgesia. J Neurosci 2011, 31:1410-1418. 10.1523/JNEUROSCI.4682-10.2011, 21273425.
-
(2011)
J Neurosci
, vol.31
, pp. 1410-1418
-
-
Lin, S.Y.1
Chang, W.J.2
Lin, C.S.3
Huang, C.Y.4
Wang, H.F.5
Sun, W.H.6
-
10
-
-
0031594975
-
5-HT2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery
-
10.1016/S0304-3959(98)00066-9, 9718253
-
Tokunaga A, Saika M, Senba E. 5-HT2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery. Pain 1998, 76:349-355. 10.1016/S0304-3959(98)00066-9, 9718253.
-
(1998)
Pain
, vol.76
, pp. 349-355
-
-
Tokunaga, A.1
Saika, M.2
Senba, E.3
-
11
-
-
0038287034
-
Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors
-
Mannisto PT, Kaakkola S. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev 1999, 51:593-628.
-
(1999)
Pharmacol Rev
, vol.51
, pp. 593-628
-
-
Mannisto, P.T.1
Kaakkola, S.2
-
12
-
-
52049118327
-
MedusaScore: an accurate force field-based scoring function for virtual drug screening
-
10.1021/ci8001167, 2665000, 18672869
-
Yin S, Biedermannova L, Vondrasek J, Dokholyan NV. MedusaScore: an accurate force field-based scoring function for virtual drug screening. J Chem Inf Model 2008, 48:1656-1662. 10.1021/ci8001167, 2665000, 18672869.
-
(2008)
J Chem Inf Model
, vol.48
, pp. 1656-1662
-
-
Yin, S.1
Biedermannova, L.2
Vondrasek, J.3
Dokholyan, N.V.4
-
13
-
-
77957237749
-
Rapid flexible docking using a stochastic rotamer library of ligands
-
10.1021/ci100218t, 2947618, 20712341
-
Ding F, Yin S, Dokholyan NV. Rapid flexible docking using a stochastic rotamer library of ligands. J Chem Inf Model 2010, 50:1623-1632. 10.1021/ci100218t, 2947618, 20712341.
-
(2010)
J Chem Inf Model
, vol.50
, pp. 1623-1632
-
-
Ding, F.1
Yin, S.2
Dokholyan, N.V.3
-
14
-
-
44649191697
-
Crystal structures of human 108 V and 108 M catechol O-methyltransferase
-
10.1016/j.jmb.2008.04.040, 18486144
-
Rutherford K, Le Trong I, Stenkamp RE, Parson WW. Crystal structures of human 108 V and 108 M catechol O-methyltransferase. J. Mol. Biol. 2008, 380:120-130. 10.1016/j.jmb.2008.04.040, 18486144.
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 120-130
-
-
Rutherford, K.1
Le Trong, I.2
Stenkamp, R.E.3
Parson, W.W.4
-
15
-
-
0021191902
-
Estimation of intrasynaptic norepinephrine concentrations at vascular neuroeffector junctions in vivo
-
10.1007/BF00504372, 6728040
-
Kopin IJ, Zukowska-Grojec Z, Bayorh MA, Goldstein DS. Estimation of intrasynaptic norepinephrine concentrations at vascular neuroeffector junctions in vivo. Naunyn Schmiedebergs Arch Pharmacol 1984, 325:298-305. 10.1007/BF00504372, 6728040.
-
(1984)
Naunyn Schmiedebergs Arch Pharmacol
, vol.325
, pp. 298-305
-
-
Kopin, I.J.1
Zukowska-Grojec, Z.2
Bayorh, M.A.3
Goldstein, D.S.4
-
16
-
-
0033232510
-
Role of norepinephrine in the pathophysiology and treatment of mood disorders
-
10.1016/S0006-3223(99)00127-4, 10560027
-
Ressler KJ, Nemeroff CB. Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biol Psychiatry 1999, 46:1219-1233. 10.1016/S0006-3223(99)00127-4, 10560027.
-
(1999)
Biol Psychiatry
, vol.46
, pp. 1219-1233
-
-
Ressler, K.J.1
Nemeroff, C.B.2
-
17
-
-
0028918413
-
Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme
-
10.1021/bi00013a008, 7703232
-
Lotta T, Vidgren J, Tilgmann C, Ulmanen I, Melen K, Julkunen I, Taskinen J. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995, 34:4202-4210. 10.1021/bi00013a008, 7703232.
-
(1995)
Biochemistry
, vol.34
, pp. 4202-4210
-
-
Lotta, T.1
Vidgren, J.2
Tilgmann, C.3
Ulmanen, I.4
Melen, K.5
Julkunen, I.6
Taskinen, J.7
-
18
-
-
0028025252
-
Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain
-
Garris PA, Ciolkowski EL, Pastore P, Wightman RM. Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain. J Neurosci 1994, 14:6084-6093.
-
(1994)
J Neurosci
, vol.14
, pp. 6084-6093
-
-
Garris, P.A.1
Ciolkowski, E.L.2
Pastore, P.3
Wightman, R.M.4
-
19
-
-
0022552098
-
Estimation of intrasynaptic norepinephrine concentrations in humans
-
10.1161/01.HYP.8.6.471, 3710555
-
Goldstein DS, Zimlichman R, Stull R, Keiser HR, Kopin IJ. Estimation of intrasynaptic norepinephrine concentrations in humans. Hypertension 1986, 8:471-475. 10.1161/01.HYP.8.6.471, 3710555.
-
(1986)
Hypertension
, vol.8
, pp. 471-475
-
-
Goldstein, D.S.1
Zimlichman, R.2
Stull, R.3
Keiser, H.R.4
Kopin, I.J.5
-
20
-
-
5644257549
-
What should we be measuring in behavioral studies of chronic pain in animals?
-
10.1016/j.pain.2004.09.028, 15494180
-
Mogil JS, Crager SE. What should we be measuring in behavioral studies of chronic pain in animals?. Pain 2004, 112:12-15. 10.1016/j.pain.2004.09.028, 15494180.
-
(2004)
Pain
, vol.112
, pp. 12-15
-
-
Mogil, J.S.1
Crager, S.E.2
-
21
-
-
62849090906
-
Animal models of pain: progress and challenges
-
Mogil JS. Animal models of pain: progress and challenges. Nat Rev Neurosci 2009, 10:283-294.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 283-294
-
-
Mogil, J.S.1
-
22
-
-
80755144045
-
Pain sensitivity risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case control study
-
10.1016/j.jpain.2011.08.006, 22074753
-
Greenspan JD, Slade GD, Bair E, Dubner R, Fillingim RB, Ohrbach R, Knott C, Mulkey F, Rothwell R, Maixner W. Pain sensitivity risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case control study. J Pain 2011, 12:T61-74. 10.1016/j.jpain.2011.08.006, 22074753.
-
(2011)
J Pain
, vol.12
-
-
Greenspan, J.D.1
Slade, G.D.2
Bair, E.3
Dubner, R.4
Fillingim, R.B.5
Ohrbach, R.6
Knott, C.7
Mulkey, F.8
Rothwell, R.9
Maixner, W.10
-
23
-
-
70449228544
-
Enzymatic O-methylation of epinephrine and other catechols
-
Axelrod J, Tomchick R. Enzymatic O-methylation of epinephrine and other catechols. J Biol Chem 1958, 233:702-705.
-
(1958)
J Biol Chem
, vol.233
, pp. 702-705
-
-
Axelrod, J.1
Tomchick, R.2
-
24
-
-
0023058914
-
Chromatographic analysis of the chiral and covalent instability of S-adenosyl-L-methionine
-
10.1021/bi00363a041, 3530324
-
Hoffman JL. Chromatographic analysis of the chiral and covalent instability of S-adenosyl-L-methionine. Biochemistry 1986, 25:4444-4449. 10.1021/bi00363a041, 3530324.
-
(1986)
Biochemistry
, vol.25
, pp. 4444-4449
-
-
Hoffman, J.L.1
-
25
-
-
0016907345
-
S-Aristeromycinyl-L-homocysteine, a Potent Inhibitor of S-Adenosylmethionine-Dependent Transmethylations
-
10.1021/jm00223a043, 1246047
-
Borchardt RT, Wu Y. S-Aristeromycinyl-L-homocysteine, a Potent Inhibitor of S-Adenosylmethionine-Dependent Transmethylations. J. Med. Chem. 1976, 19:197-198. 10.1021/jm00223a043, 1246047.
-
(1976)
J. Med. Chem.
, vol.19
, pp. 197-198
-
-
Borchardt, R.T.1
Wu, Y.2
-
26
-
-
0018829577
-
Effects of increasing serotonergic receptor activity in brain on analgesic activity in rats
-
10.1016/0014-4886(80)90108-9, 6966578
-
Lin MT, Chandra A, Chi ML, Kau CL. Effects of increasing serotonergic receptor activity in brain on analgesic activity in rats. Exp Neurol 1980, 68:548-554. 10.1016/0014-4886(80)90108-9, 6966578.
-
(1980)
Exp Neurol
, vol.68
, pp. 548-554
-
-
Lin, M.T.1
Chandra, A.2
Chi, M.L.3
Kau, C.L.4
-
27
-
-
0031743994
-
The analgesic effects of selective serotonin reuptake inhibitors
-
10.1177/026988119801200413, 10065917
-
Smith AJ. The analgesic effects of selective serotonin reuptake inhibitors. J Psychopharmacol 1998, 12:407-413. 10.1177/026988119801200413, 10065917.
-
(1998)
J Psychopharmacol
, vol.12
, pp. 407-413
-
-
Smith, A.J.1
-
28
-
-
0017612986
-
Serotonin-containing neurons: their possible role in pain and analgesia
-
Messing RB, Lytle LD. Serotonin-containing neurons: their possible role in pain and analgesia. Pain 1977, 4:1-21.
-
(1977)
Pain
, vol.4
, pp. 1-21
-
-
Messing, R.B.1
Lytle, L.D.2
-
29
-
-
0035120656
-
Antidepressants as analgesics: a review of randomized controlled trials
-
1408040, 11212591
-
Lynch ME. Antidepressants as analgesics: a review of randomized controlled trials. J Psychiatry Neurosci 2001, 26:30-36. 1408040, 11212591.
-
(2001)
J Psychiatry Neurosci
, vol.26
, pp. 30-36
-
-
Lynch, M.E.1
-
30
-
-
23844432593
-
Mechanism-based treatment in chronic neuropathic pain: the role of antidepressants
-
10.2174/1381612054864993, 16178755
-
Coluzzi F, Mattia C. Mechanism-based treatment in chronic neuropathic pain: the role of antidepressants. Curr Pharm Des 2005, 11:2945-2960. 10.2174/1381612054864993, 16178755.
-
(2005)
Curr Pharm Des
, vol.11
, pp. 2945-2960
-
-
Coluzzi, F.1
Mattia, C.2
-
31
-
-
0035379749
-
Antidepressants in the management of cancer pain
-
10.1007/s11916-001-0036-8, 11309210
-
Mays TA. Antidepressants in the management of cancer pain. Curr Pain Headache Rep 2001, 5:227-236. 10.1007/s11916-001-0036-8, 11309210.
-
(2001)
Curr Pain Headache Rep
, vol.5
, pp. 227-236
-
-
Mays, T.A.1
-
32
-
-
0028113008
-
A double-blind placebo controlled trial of fluoxetine in fibromyalgia
-
10.3109/03009749409103725, 7973479
-
Wolfe F, Cathey MA, Hawley DJ. A double-blind placebo controlled trial of fluoxetine in fibromyalgia. Scand J Rheumatol 1994, 23:255-259. 10.3109/03009749409103725, 7973479.
-
(1994)
Scand J Rheumatol
, vol.23
, pp. 255-259
-
-
Wolfe, F.1
Cathey, M.A.2
Hawley, D.J.3
-
33
-
-
0029956785
-
A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia
-
10.1002/art.1780391111, 8912507
-
Goldenberg D, Mayskiy M, Mossey C, Ruthazer R, Schmid C. A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. Arthritis Rheum 1996, 39:1852-1859. 10.1002/art.1780391111, 8912507.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1852-1859
-
-
Goldenberg, D.1
Mayskiy, M.2
Mossey, C.3
Ruthazer, R.4
Schmid, C.5
-
34
-
-
0037082564
-
A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia
-
10.1016/S0002-9343(01)01089-0, 11893345
-
Arnold LM, Hess EV, Hudson JI, Welge JA, Berno SE, Keck PE. A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. Am J Med 2002, 112:191-197. 10.1016/S0002-9343(01)01089-0, 11893345.
-
(2002)
Am J Med
, vol.112
, pp. 191-197
-
-
Arnold, L.M.1
Hess, E.V.2
Hudson, J.I.3
Welge, J.A.4
Berno, S.E.5
Keck, P.E.6
-
35
-
-
0029062173
-
A randomized controlled trial of citalopram in the treatment of fibromyalgia
-
10.1016/0304-3959(94)00218-4, 7478688
-
Norregaard J, Volkmann H, Danneskiold-Samsoe B. A randomized controlled trial of citalopram in the treatment of fibromyalgia. Pain 1995, 61:445-449. 10.1016/0304-3959(94)00218-4, 7478688.
-
(1995)
Pain
, vol.61
, pp. 445-449
-
-
Norregaard, J.1
Volkmann, H.2
Danneskiold-Samsoe, B.3
-
36
-
-
4444381930
-
A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder
-
10.1002/art.20485, 15457467
-
Arnold LM, Lu Y, Crofford LJ, Wohlreich M, Detke MJ, Iyengar S, Goldstein DJ. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis Rheum 2004, 50:2974-2984. 10.1002/art.20485, 15457467.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2974-2984
-
-
Arnold, L.M.1
Lu, Y.2
Crofford, L.J.3
Wohlreich, M.4
Detke, M.J.5
Iyengar, S.6
Goldstein, D.J.7
-
37
-
-
43549091316
-
Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial
-
10.1016/j.pain.2008.02.024, 18395345
-
Russell IJ, Mease PJ, Smith TR, Kajdasz DK, Wohlreich MM, Detke MJ, Walker DJ, Chappell AS, Arnold LM. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. Pain 2008, 136:432-444. 10.1016/j.pain.2008.02.024, 18395345.
-
(2008)
Pain
, vol.136
, pp. 432-444
-
-
Russell, I.J.1
Mease, P.J.2
Smith, T.R.3
Kajdasz, D.K.4
Wohlreich, M.M.5
Detke, M.J.6
Walker, D.J.7
Chappell, A.S.8
Arnold, L.M.9
-
38
-
-
78149461246
-
A review of SSRIs and SNRIs in neuropathic pain
-
10.1517/14656566.2010.507192, 20642317
-
Lee YC, Chen PP. A review of SSRIs and SNRIs in neuropathic pain. Expert Opin Pharmacother 2010, 11:2813-2825. 10.1517/14656566.2010.507192, 20642317.
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 2813-2825
-
-
Lee, Y.C.1
Chen, P.P.2
-
39
-
-
6344277909
-
The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis
-
10.1073/pnas.0406650101, 524068, 15475574
-
Khare SD, Caplow M, Dokholyan NV. The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2004, 101:15094-15099. 10.1073/pnas.0406650101, 524068, 15475574.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15094-15099
-
-
Khare, S.D.1
Caplow, M.2
Dokholyan, N.V.3
-
40
-
-
6344265879
-
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain
-
10.1086/425589, 1182110, 15457404
-
Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, et al. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 2004, 75:807-821. 10.1086/425589, 1182110, 15457404.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 807-821
-
-
Chen, J.1
Lipska, B.K.2
Halim, N.3
Ma, Q.D.4
Matsumoto, M.5
Melhem, S.6
Kolachana, B.S.7
Hyde, T.M.8
Herman, M.M.9
Apud, J.10
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