Virulence characteristics and antimicrobial susceptibility of uropathogenic Escherichia coli strains

Genetics and Molecular Research

Volumn 10, Issue 4, 2011, Pages 4114-4125

  Oliveira, F A ^a   Paludo, K S ^b   Arend, L N V S ^c   Farah, S M S S ^c   Pedrosa, F O ^a   Souza, E M ^a   Surek, M ^a   Picheth, G ^a   Fadel Picheth, C M T ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^c Laboratory of Bacteriology   (Brazil)

Author keywords

Antimicrobial resistance; Escherichia coli; UPEC; Urinary tract infection; Uropathogen; Virulence genes

Indexed keywords

ADHESIN; ADHESIN P; ADHESIN S; AEROBACTIN; AFIMBRIAL ADHESIN I; ALPHA HEMOLYSIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; CEFALOTIN; CEFEPIME; CEFOXITIN; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; CYTOTOXIC NECROTIZING FACTOR 1; GENTAMICIN; IMIPENEM; NALIDIXIC ACID; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

AER GENE; AFA GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CNF1 GENE; CONTROLLED STUDY; DISK DIFFUSION; GENE; HLY GENE; LEUKOCYTE COUNT; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PAP GENE; SFA GENE; TRAT GENE; UROPATHOGENIC ESCHERICHIA COLI; BACTERIAL GENE; ESCHERICHIA COLI INFECTION; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; PATHOGENICITY; URINE; VIRULENCE;

DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI INFECTIONS; GENES, BACTERIAL; HUMANS; MULTIPLEX POLYMERASE CHAIN REACTION; UROPATHOGENIC ESCHERICHIA COLI; VIRULENCE; VIRULENCE FACTORS;

EID: 84859606110     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2011.October.31.5     Document Type: Article

References (40)

1. Abe CM, Salvador FA, Falsetti IN, Vieira MA, et al. (2008). Uropathogenic Escherichia coli (UPEC) strains may carry virulence properties of diarrhoeagenic E. coli. FEMS Immunol. Med. Microbiol. 52: 397-406.
2. Antão EM, Wieler LH and Ewers C (2009). Adhesive threads of extraintestinal pathogenic Escherichia coli. Gut. Pathog. 1: 22.
3. Aranda KR, Fagundes-Neto U and Scaletsky IC (2004). Evaluation of multiplex PCRs for diagnosis of infection with diarrheagenic Escherichia coli and Shigella spp. J. Clin. Microbiol. 42: 5849-5853.
4. Arslan H, Azap OK, Ergönül Ö and Timurkaynak F (2005). Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-adquired urinary tract infections in Turkey. J. Antimicrob. Chemother. 56: 914-918.
5. Binns MM, Mayden J and Levine RP (1982). Further characterization of complement resistance conferred on Escherichia coli by the plasmid genes traT of R100 and iss of ColV, I-K94. Infect. Immun. 35: 654-659.
6. Blanco M, Blanco JE, Alonso MP, Mora et al. (1997a). Detection of pap, sfa and afa adhesin-encoding operons in uropathogenic Escherichia coli strains: relationship with expression of adhesins and production of toxins. Res. Microbial. 148:745-755.
7. Blanco M, Blanco JE, Rodriguez E, Abalia I, et al. (1997b). Detection of virulence genes in uropathogenic Escherichia coli by polymerase chain reaction (PCR): comparison with results obtained using phenotypic methods. J. Clin. Micro. 31: 37-43.
8. Boehm DF, Welch RA and Snyder IS (1990). Domains of Escherichia coli hemolysin (HlyA) involved in binding of calcium and erythrocyte membranes. Infect. Immun. 58: 1959-1964.
9. Chung A, Arianayagam M and Rashid P (2010). Bacterial cystitis in women. Aust. Fam. Physician. 39: 295-298.
10. CLSI (2010). Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement. Clinical and Laboratory Standards Institute, Wayne.
11. Guyer DM, Kao JS and Mobley HL (1998). Genomic analysis of a pathogenicity island in uropathogenic Escherichia coli CFT073: distribution of homologous sequences among isolates from patients with pyelonephritis, cystitis, and Catheter-associated bacteriuria and from fecal samples. Infect. Immun. 66: 4411-4417.
12. Houdouin V, Bonacorsi S, Bidet P, Bingen-Bidois M, et al. (2006). Phylogenetic background and carriage of pathogenicity island-like domains in relation to antibiotic resistance profiles among Escherichia coli urosepsis isolates. J. Antimicrob. Chemother. 58: 748-751.
13. Johnson JR (1991). Virulence factors in Escherichia coli urinary tract infection. Clin. Microbiol. Rev. 4: 80-128.
14. Johnson JR and Stell AL (2000). Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J. Infect. Dis. 181: 261-272.
15. Johnson JR, Owens K, Gajewski A and Kuskowski MA (2005). Bacterial characteristics in relation to clinical source of Escherichia coli isolates from women with acute cystitis or pyelonephritis and uninfected women. J. Clin. Microbiol. 43: 6064-6072.
16. Kaper JB, Nataro JP and Mobley HL (2004). Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2: 123-140.
17. Korhonen TK, Vaisanen-Rhen V, Rhen M, Pere A, et al. (1984). Escherichia coli fimbriae recognizing sialyl galactosides. J. Bacteriol. 159: 762-766.
18. Lloyd AL, Rasko DA and Mobley HLT (2007). Defining genomic islands and uropathogen-specific genes in uropathogenic Escherichia coli. J. Bacteriol. 189: 3532-3546.
19. Marrs CF, Zhang L, Tallman P, Manning SD, et al. (2002). Variations in 10 putative uropathogen virulence genes among urinary, faecal and peri-urethral Escherichia coli. J. Med. Microbiol. 51: 138-142.
20. Marrs CF, Zhang L and Foxman B (2005). Escherichia coli mediated urinary tract infections: are there distinct uropathogenic E. coli (UPEC) pathotypes? FEMS Microbiol. Lett. 252: 183-190.
21. McIsaac J, Mazzulli T, Moineddin R, Raboud J, et al. (2004). Uropathogen antibiotic resistance in adult women presenting to family physicians with acute uncomplicated cystitis. Can. J. Infect. Dis. Med. Microbiol. 15: 266-270.
22. Mellata M, Dho-Moulin M, Dozois CM, Curtiss R, III, et al. (2003). Role of virulence factors in resistance of avian pathogenic Escherichia coli to serum and in pathogenicity. Infect. Immun. 71: 536-540.
23. Oelschlaeger TA, Dobrindt U and Hacker J (2002). Pathogenicity islands of uropathogenic E. coli and the evolution of virulence. Int. J. Antimicrob. Agents 19: 517-521.
24. Ostolaza H and Goni FM (1995). Interaction of the bacterial protein toxin alpha-haemolysin with model membranes: protein binding does not always lead to lytic activity. FEBS Lett. 371: 303-306.
25. Park HK, Jung YJ, Chae HC, Shin YJ, et al. (2009). Comparison of Escherichia coli uropathogenic genes (kps, usp and ireA) and enteroaggregative genes (aggR and aap) via multiplex polymerase chain reaction from suprapubic urine specimens of young children with fever. Scand. J. Urol. Nephrol. 43: 51-57.
26. Piatti G, Mannini A, Balistreri M and Schito AM (2008). Virulence factors in urinary Escherichia coli strains: phylogenetic background and quinolone and fluoroquinolone resistance. J. Clin. Microbiol. 46: 480-487.
27. Roberts JA, Britt-Inger M, Ilver D, Haslam D, et al. (1994). The Gal(al-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract. Proc. Natl. Acad. Sci. U. S. A. 91: 11889-11893.
28. Russo TA, Carlino UB, Mong A and Jodush ST (1999). Identification of genes in an extraintestinal isolate of Escherichia coli with increased expression after exposure to human urine. Infect. Immun. 67: 5306-5314.
29. Santo E, Macedo C and Marin JM (2006). Virulence factors of uropathogenic Escherichia coli from a university hospital in Ribeirão Preto, São Paulo, Brazil. Rev. Inst. Med. Trop. São Paulo 48: 185-188.
30. Scheffer J, Konig W, Braun V and Goebel W (1988). Comparison of four hemolysin-producing organisms (Escherichia coli, Serratia marcescens, Aeromonas hydrophila, and Listeria monocytogenes) for release of inflammatory mediators from various cells. J. Clin. Microbiol. 26: 544-551.
31. Smith YC, Rasmussen SB, Grande KK, Conran RM, et al. (2008). Hemolysin of uropathogenic Escherichia coli evokes extensive shedding of the uroepithelium and hemorrhage in bladder tissue within the first 24 hours after intraurethral inoculation of mice. Infect. Immun. 76: 2978-2990.
32. Snyder JA, Haugen BJ, Buckles EL, Lockatell CV, et al. (2004). Transcriptome of uropathogenic Escherichia coli during urinary tract infection. Infect. Immun. 72: 6373-6381.
33. Stamm WE (2006). Theodore E. Woodward Award: host-pathogen interactions in community-acquired urinary tract infections. Trans. Am. Clin. Climatol. Assoc. 117: 75-83.
34. Takahashi A, Kanamaru S, Kurazono H, Kunishima Y, et al. (2006). Escherichia coli isolates associated with uncomplicated and complicated cystitis and asymptomatic bacteriuria possess similar phylogenies, virulence genes, and O-serogroup profiles. J. Clin. Microbiol. 44: 4589-4592.
35. Takahashi A, Muratani T, Yasuda M, Takahashi S, et al. (2009). Genetic profiles of fluoroquinolone-resistant Escherichia coli isolates obtained from patients with cystitis: phylogeny, virulence factors, PAIusp subtypes, and mutation patterns. J. Clin. Microbiol. 47: 791-795.
36. Talan DA, Krishnadasan A, Abrahamian FM, Stamm WE, et al. (2008). Prevalence and risk factor analysis of trimethoprim-sulfamethoxazole-and fluoroquinolone-resistant Escherichia coli infection among emergency department patients with pyelonephritis. Clin. Infect. Dis. 47: 1150-1158.
37. Wiles TJ, Dhakal BK, Eto DS and Mulvey MA (2008a). Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins. Mol. Biol. Cell 19: 1427-1438.
38. Wiles TJ, Kulesus RR and Mulvey MA (2008b). Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp. Mol. Pathol. 85: 11-19.
39. Yamamoto S, Terai A, Yuri K, Kurazono H, et al. (1995). Detection of urovirulence factors in Escherichia coli by multiplex polymerase chain reaction. FEMS Immunol. Med. Microbiol. 12: 85-90.
40. Zhang L and Foxman B (2003). Molecular epidemiology of Escherichia coli mediated urinary tract infections. Front Biosci. 8: e235-e244.