Antiinflammatory activities of Hungarian Stachys species and their iridoids

Phytotherapy Research

Volumn 26, Issue 4, 2012, Pages 505-509

  Háznagy Radnai, Erzsébet ^a   Balogh, Úgnes ^a   Czigle, Szilvia ^b   Máthé, Imre ^a,c   Hohmann, Judit ^a   Blazsõ, Gábor ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b Physics and Informatics   (Slovakia)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

antiinflammatory activity; carrageenan; iridoid glycosides; Stachys species

Indexed keywords

ACETYLHARPAGIDE; AJUGOSIDE; ANTIINFLAMMATORY AGENT; AUCUBIN; CARRAGEENAN; DICLOFENAC; HARPAGIDE; HARPAGOSIDE; IRIDOID; PLANT EXTRACT; STACHYS ALPINA EXTRACT; STACHYS ANNUA EXTRACT; STACHYS BYZANTHINA EXTRACT; STACHYS EXTRACT; STACHYS GERMANICA EXTRACT; STACHYS GRANDIFLORA EXTRACT; STACHYS OFFICINALIS EXTRACT; STACHYS PALUSTRIS EXTRACT; STACHYS RECTA EXTRACT; STACHYS SYLVATICA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG POTENCY; DRUG STRUCTURE; IN VIVO STUDY; NONHUMAN; PAW EDEMA; RAT; STACHYS ALPINA; STACHYS ANNUA; STACHYS BYZANTHINA; STACHYS GERMANICA; STACHYS GRANDIFLORA; STACHYS OFFICINALIS; STACHYS PALUSTRIS; STACHYS RECTA; STACHYS SYLVATICA;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; DICLOFENAC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EDEMA; GLYCOSIDES; INJECTIONS, INTRAPERITONEAL; IRIDOID GLUCOSIDES; MALE; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PYRANS; RATS; RATS, SPRAGUE-DAWLEY; STACHYS;

RATTUS; STACHYS; STACHYS GERMANICA; STACHYS OFFICINALIS; STACHYS RECTA;

EID: 84859600593     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3582     Document Type: Article

References (28)

1. Allen DE, Hatfield G,. 2004. Medicinal Plants in Folk Tradition-an Ethnobotany of Britain and Ireland. Timber Press: Portland, Cambridge.
2. Ball PW,. 1972. Stachys. In Flora Europaea, Vol. 3, Tutin TG, Heywood VH, Burges NA, et al. (eds). University Press: Cambridge, 151-157.
3. Benito PB, Lanza AMD, Sen AMS, et al,. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Med 66: 324-328.
4. Delazar A, Celik S, Gokturk RS, Unal O, Nahar L, Sarker SD,. 2005. Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity. Pharmazie 60: 878-880.
5. Ebrahimabadi AH, Ebrahimabadi EH, Djafari-Bidgoli Z, Kashi FJ, Mazoochi A, Batooli H,. 2010. Composition and antioxidant and antimicrobial activity of the essential oil and extracts of Stachys inflata Benth from Iran. Food Chem 119: 452-458.
6. Gruenwald J, Brendler T, Jaenicke C,. 2000. PDR for Herbal Medicines. Medical Economics Company: Montvale.
7. Gyurkovska V, Alipieva K, Maciuk A, et al,. 2011. Anti-inflammatory activity of Devil's claw in vitro systems and their active constituents. Food Chem 125: 171-178.
8. Hartwell JL,. 1982. Plants Used Against Cancer. A Survey. Quarterman Publications Inc.: Massachusetts.
9. Háznagy-Radnai E,. 2007. Examination of the volatile and non-volatile components of Hungarian Stachys species. PhD Thesis. University of Szeged, Hungary.
10. Háznagy-Radnai E, Czigle S, Janicsák G, Máthé I,. 2006a. Iridoids of Stachys species growing in Hungary. JPC J Planar Chromat Modern TLC 19: 187-190.
11. Háznagy-Radnai E, Czigle S, Zupkõ I, Falkay G, Máthé I,. 2006b. Comparison of antioxidant activity in enzyme-independent system of six Stachys species. Fitoterapia 77: 521-524.
12. Hegnauer R,. 1989. Chemotaxonomie der Pflanzen Band 8. Birkhauser Verlag: Basel, Boston, Berlin.
13. Kukic J, Dobric S, Petrovic S,. 2007. Influence of some Stachys taxa on carrageenan-induced paw edema in rats. Pharm Biol 45: 560-563.
14. Kukic J, Petrovic S, Niketic M,. 2006. Antioxidant activity of four endemic Stachys taxa. Biol Pharm Bull 29: 725-729.
15. Kupeli E, Tatli II, Akdemir ZS, Yesilada E,. 2007. Bioassay-guided isolation of anti-inflammatory and antinociceptive glycoterpenoids from the flowers of Verbascum lasianthum Boiss. ex Bentham. J Ethnopharmacol 110: 444-450.
16. Maleki N, Garjani A, Nazemiyeh H, et al,. 2001. Potent anti-inflammatory activities of hydroalcoholic extract from aerial parts of Stachys inflata on rats. J Ethnopharmacol 75: 213-218.
17. Matkowski A, Piotrowska M,. 2006. Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. Fitoterapia 77: 346-353.
18. Miyase T, Yamamoto R, Ueno A,. 1996. Betonicosides A-D and betonicolide, diterpenoids from the roots of Stachys officinalis. Chem Pharm Bull 44: 1610-1613.
19. Park KS, Chang I,. 2004. Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264.7 cells. Planta Med 70: 778-779.
20. Recio MC, Giner RM, Mánez S, Ríos JL,. 1994. Structural consideration on the iridoids as anti-inflammatory agents. Planta Med 60: 232-234.
21. Rezazadeh SH, Zaringhalam J, Manaheji H, Kebryaeezadeh A,. 2009. Anti-inflammatory and anti-hyperalgesic activities of Stachys athorecalyx extracts on CFA-induced inflammation. J Med Plant Res 3: 368-376.
22. Shin TY,. 2004. Stachys riederi inhibits mast cell-mediated acute and chronic allergic reactions. Immunopharmacol Immunotoxicol 26: 621-630.
23. Skaltsa HD, Bermejo P, Lazari D, Loukis AE,. 2000. Inhibition of prostaglandin E-4 and leukotriene C-4 in mouse peritoneal macrophages and thromboxane B-2 production in human platelets by flavonoids from Stachys chrysantha and Stachys candida. Biol Pharm Bull 23: 47-53.
24. Skaltsa HD, Demetzos C, Lazari D, Sokovic M,. 2003. Essential oil analysis and antimicrobial activity of eight Stachys species from Greece. Phytochemistry 64: 743-752.
25. Skaltsa H, Georgakopoulos P, Lazari D, et al,. 2007. Flavonoids as chemotaxonomic markers in the polymorphic Stachys swainsonii (Lamiaceae). Biochem Syst Ecol 35: 317-320.
26. Skaltsa HD, Lazari D, Chinon IB, et al,. 1999. Composition and antibacterial activity of the essential oils of Stachys candida and S. chrysantha from Southern Greece. Planta Med 65: 255-256.
27. Villasenor IM,. 2007. Bioactivities of iridoids. Anti-Inflamm Anti-Allergy Agents Med Chem 6: 307-314.
28. Winyard GP, Willoughby DA,. 2003. Inflammation Protocols. Humana Press: Totowa, New Jersey.