Prevalence and antimicrobial susceptibility of methicillin-resistant staphylococcus aureus among pigs in Belgium

Microbial Drug Resistance

Volumn 18, Issue 2, 2012, Pages 125-131

  Crombé, Florence ^a,b   Willems, Glenda ^a,f   Dispas, Marc ^a   Hallin, Marie ^c   Denis, Olivier ^c   Suetens, Carl ^d,g   Gordts, Bart ^e   Struelens, Marc ^c,g   Butaye, Patrick ^a,b  

^a VETERINARY AND AGROCHEMICAL RESEARCH CENTRE   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

^e ZiekenhuisNetwerk Antwerpen   (Belgium)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL ECDC   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CHLORAMPHENICOL; CIPROFLOXACIN; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; KANAMYCIN; LINCOMYCIN; LINCOSAMIDE; LINEZOLID; MACROLIDE; PRISTINAMYCIN; PSEUDOMONIC ACID; QUINOLONE DERIVATIVE; RIFAMPICIN; SULFONAMIDE; TETRACYCLINE; TOBRAMYCIN; TRIMETHOPRIM; TYLOSIN;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATE; BELGIUM; CONTROLLED STUDY; DISK DIFFUSION; EUROPE; FARM ANIMAL; GROUPS BY AGE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SEROPREVALENCE; SOW (SWINE); SPUTUM; SWINE;

ANIMAL HUSBANDRY; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; BELGIUM; DRUG RESISTANCE, BACTERIAL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; PREVALENCE; STAPHYLOCOCCAL INFECTIONS; SWINE; SWINE DISEASES;

IVA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SUIDAE;

EID: 84859599903     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2011.0138     Document Type: Article

References (36)

1. Argudin, M.A., B.A. Tenhagen, A. Fetsch, J. Sachsenroder, A. Kasbohrer, A. Schroeter, J.A. Hammerl, S. Hertwig, R. Helmuth, J. Braunig, M.C. Mendoza, B. Appel, M.R. Rodicio, and B. Guerra. 2001. Virulence and resistance determinants of German Staphylococcus aureus ST398 isolates from nonhuman sources. Appl. Environ. Microbiol. 77:3052-3060.
2. Battisti, A., A. Franco, G. Merialdi, H. Hasman, M. Iurescia, R. Lorenzetti, F. Feltrin, M. Zini, and F.M. Aarestrup. 2011. Heterogeneity among methicillin-resistant Staphylococcus aureus from Italian pig finishing holdings. Vet. Microbiol. 142:361-366.
3. Broens, E.M., E.A. Graat, P.J. van der Wolf, A.W. van de Giessen, E. van Duijkeren, J.A. Wagenaar, A. van Nes, D.J. Mevius, and M.C. de Jong. 2011. MRSA CC398 in the pig production chain. Prev. Vet. Med. 98:182-189.
4. Broens, E.M., E.A. Graat, B. Engel, R.A. van Oosterom, A.W. van de Giessen, and P.J. van der Wolf. 2011. Comparison of sampling methods used for MRSA-classification of herds with breeding pigs. Vet. Microbiol. 147:440-444.
5. Cuny C., A. Friedrich, S. Kozytska, F. Layer, U. Nubel, K. Ohlsen, B. Strommenger, B. Walther, L. Wieler, and W. Witte. 2010. Emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different animal species. Int. J. Med. Microbiol. 300:109-117.
6. de Neeling, A.J., M.J. van den Broek, E.C. Spalburg, M.G. van Santen-Verheuvel, W.D. Dam-Deisz, H.C. Boshuizen, A.W. van de Giessen, E. van Duijkeren, and X.W. Huijsdens. 2007. High prevalence of methicillin resistant Staphylococcus aureus in pigs. Vet. Microbiol. 122:366-372. (Pubitemid 46756022)
7. Denis, O., J. Magdalena, A. Deplano, C. Nonhoff, E. Hendrickx, and M.J. Struelens. 2002. Molecular epidemiology of resistance to macrolides- lincosamides-streptogramins in methicillin-resistant Staphylococcus aureus (MRSA) causing bloodstream infections in patients admitted to Belgian hospitals. J. Antimicrob. Chemother. 50:755-757. (Pubitemid 35331698)
8. Denis, O., C. Suetens, M. Hallin, B. Catry, I. Ramboer, M. Dispas, G. Willems, B. Gordts, P. Butaye, and M.J. Struelens. 2009. Methicillin-resistant Staphylococcus aureus ST398 in swine farm personnel, Belgium. Emerg. Infect. Dis. 15:1098-1101.
9. Dewaele I., W. Messens, I. De Man, P. Delputte, L. Herman, P. Butaye, M. Heyndrickx and G. Rasschaert. 2011. Sampling, prevalence and characterization of methicillingresistant Staphylococcus aureus on two Belgian pig farms. Vet. Sci. Dev. 1:e1. doi:10.4081/vsd.2011.1.
10. EFSA. 2009. Analysis of the baseline-survey on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in holdings with breeding pigs, in the EU, 2008. Part A: MRSA prevalence estimates; on request from the European Commission. EFSA J. 7:1376, 82 pp. doi:10.2903/j.efsa.2009.1376. Available at www.efsa.europe.eu. (Online.
11. Enright, M.C., N.P.J. Day, C.E. Davies, S.J. Peacock, and B.G. Spratt. 2000. Multilocus Sequence Typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J. Clin. Microbiol. 38:1008-1015. (Pubitemid 30140551)
12. Harmsen, D., H. Claus, W. Witte, J. Rothgaönger, H. Claus, D. Turnwald, and U. Vogel. 2003. Typing of methicillinresistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management. J. Clin. Microbiol. 41:5442-5448. (Pubitemid 37543228)
13. Hallin, M., A. Deplano, O. Denis, R. De Mendonca, R. De Ryck, M.J. Struelens. 2007. Validation of pulsed-field gel electrophoresis and spa typing for long-term, nationwide epidemiological surveillance studies of Staphylococcus aureus infections. J Clin. Microbiol. 45:127-133. (Pubitemid 46106418)
14. Hallin, M., R. De Mendonca, O. Denis, A. Lefort, F. El Garch, P. Butaye, K. Hermans, and M.J. Struelens. 2011. Diversity of accessory genome of human and livestockassociated ST398 methicillin resistant Staphylococcus aureus strains. Infect. Genet. Evol. 11:290-299.
15. Kadlec, K., R. Ehricht, S. Monecke, U. Steinacker, H. Kaspar, J. Mankertz, and S. Schwarz. 2009. Diversity of antimicrobial resistance pheno-and genotypes of methicillinresistant Staphylococcus aureus ST398 from diseased swine. J. Antimicrobial. Chemoth. 64:1156-1164.
16. Kadlec, K., and S. Schwarz. 2009. Novel ABC transporter gene, vga (C), located on a multiresistant plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Anti. Microbial. Antimicrob. Agents Chemother. 53:3589-3591.
17. Lewis, H.C., K. Molbak, C. Reese, F.M. Aarestrup, M. Selchau, M. Sorum, and R.L. Skov. 2008. Pigs as source of methicillin-resistant Staphylococcus aureus CC398 infections in humans, Denmark. Emerg. Infect. Dis. 14:1383-1389.
18. Maes, N., J. Magdalena, S. Rottiers, Y. De Gheldre, and M.J. Struelens. 2002. Evaluation of a triplex PCR assay to discriminate Staphylococcus aureus from coagulase-negative staphylococci and determine methicillin-resistance from blood cultures. J. Clin. Microbiol. 40:1514-1517. (Pubitemid 34279929)
19. Salmenlinna, S., O. Lyytikainen, A. Vainio, A.L. Myllyniemi, S. Raulo, M. Kanerva, M. Rantala, K. Thomson, J. Seppanen, and J. Vuopio. 2010. Human Cases of methicillin-resistant Staphylococcus aureus CC398, Finland. Emerg. Infect. Dis. 16:1626-1629.
20. Schijffelen, M.J., C.H. Boel, J.A. van Strijp, and A.C. Fluit. 2010. Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis. BMC Genomics 11:376.
21. StataCorp. 2005. Stata Statistical Software: Release 9. College Station, StataCorp LP, TX.
22. van Belkum, A., D.C. Melles, J.K. Peeters, W.B. van Leeuwen, et al. 2008. Methicillin-resistant and-susceptible Staphylococcus aureus sequence type 398 in pigs and humans. Emerg. Infect. Dis. 14:479-483. (Pubitemid 351451400)
23. van Cleef, B.A., E.J. Verkade, M.W. Wulf, A.G. Buiting, A. Voss, X.W. Huijsdens, W. van Pelt, M.N. Mulders, and J.A. Kluytmans. 2010. Prevalence of livestock-associated MRSA in communities with high pig-densities in The Netherlands. PLoS One 5:e9385.
24. van Cleef, B.A., D.L. Monnet, A. Voss, K. Krziwanek, F. Allerberger, M. Struelens, H. Zemlickova, R.L. Skov, J. Vuopio-Varkila, C. Cuny, A.W. Friedrich, I. Spiliopoulou, J. Pászti, H. Hardardottir, A. Rossney, A. Pan, A. Pantosti, M. Borg, H. Grundmann, M. Mueller-Premru, B. Olsson-Liljequist,A. Widmer, S.Harbarth,A. Schweiger, S.Unal, and J.A.J.W. Kluytmans. 2011. Livestock-associated methicillinresistant Staphylococcus aureus in Humans, Europe. Emerg. Infect. Dis. 17:502-505.
25. Van den Eede, A., A. Martens, U. Lipinska, M. Struelens, A. Deplano, O. Denis, F. Haesebrouck, F. Gasthuys, and K. Hermans. 2009. High occurrence of methicillin-resistant Staphylococcus aureus ST398 in equine nasal samples. Vet. Microbiol. 133:138-144. (Pubitemid 50235802)
26. Vanderhaeghen, W., K. Hermans, F. Haesebrouck, and P. Butaye. 2010. Methicillin-resistant Staphylococcus aureus (MRSA) in food production animals. Epidemiol. Infect. 138:606-625.
27. Vanderhaeghen, W., T. Cerpentier, C. Adriaensen, J. Vicca, K. Hermans, and P. Butaye. 2010. Methicillin-resistant Staphylococcus aureus (MRSA) ST398 associated with clinical and subclinical mastitis in Belgian cows. Vet. Microbiol. 144:166-171.
28. van Duijkeren, E., R. Ikawaty, M.J. Broekhuizen-Stins, M.D. Jansen, E.C. Spalburg, A.J. de Neeling, J.G. Allaart, A. van Nes, J.A. Wagenaar, and A.C. Fluit. 2008. Transmission of methicillin-resistant Staphylococcus aureus strains between different kinds of pig farms. Vet. Microbiol. 126:383-389. (Pubitemid 350192090)
29. Voss, A., F. Loeffen, J. Bakker, C. Klaassen, and M. Wulf. 2005. Methicillin-resistant Staphylococcus aureus in pig farming. Emerg. Infect. Dis. 11:1965-1966. (Pubitemid 43356102)
30. Wassenberg, M.W., M.C. Bootsma, A. Troelstra, J.A. Kluytmans, and M.J. Bonten. 2011. Transmissibility of livestock-associated methicillin-resistant Staphylococcus aureus (ST398) in Dutch hospitals. Clin. Microbiol. Infect. 17:316-319.
31. Weese, J.S., A. Zwambag, T. Rosendal, R. Reid-Smith, and R. Friendship. 2010. Longitudinal investigation of methicillin-resistant Staphylococcus aureus in piglets. Zoonoses Public Health 58:238-243.
32. Welinder-Olsson, C., K. Floren-Johansson, L. Larsson, S. Oberg, L. Karlsson, and C. Ahren. 2008. Infection with Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus t034. Emerg. Infect. Dis. 14:1271-1272.
33. Wulf, M.W., A. Markestein, F.T. van der Linden, A. Voss, C. Klaassen, and C.M. Verduin. 2008. First outbreak of methicillin-resistant Staphylococcus aureus ST398 in a Dutch hospital, June 2007. Euro. Surveill. 13.
34. Wulf, M.W., M. Sorum, A. van Nes, R. Skov, W.J. Melchers, C.H. Klaassen, and A. Voss. 2008. Prevalence of methicillin-resistant Staphylococcus aureus among veterinarians: An international study. Clin. Microbiol. Infect. 14:29-34. (Pubitemid 350226567)
35. Yu, F., Z. Chen, C. Liu, X. Zhang, X. lin, S. Chi, T. Zhou, Z. Chen, and X. Chen. 2008. Prevalence of Staphylococcus aureus carrying Panton-Valentine leukocidin genes among isolates from hospitalised patients in China. Clin. Microbiol. Infect. 14:381-384. (Pubitemid 351356531)
36. Zhang, K., J.A. McClure, S. Elsayed, T. Louie, and J.M. Conly. 2005. Novel multiplex PCR assay for characterization and concomitant subtyping of staphylococcal cassette chromosome mec types I to V in methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 43:5026-5033. (Pubitemid 41483999)