Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana district of Ghana

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Ghansah, Anita ^a   Rockett, Kirk A ^b   Clark, Taane G ^c   Wilson, Michael D ^a   Koram, Kwadwo A ^a   Oduro, Abraham R ^d   Amenga Etego, Lucas ^b,d   Anyorigiya, Thomas ^c   Hodgson, Abraham ^d   Milligan, Paul ^c   Rogers, William O ^e   Kwiatkowski, Dominic P ^b,f  

^a University of Ghana   (Ghana)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d NAVRONGO HEALTH RESEARCH CENTRE   (Ghana)

^e US Naval Medical Research Unit No 2 Jakarta   (Indonesia)

^f WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN C; HEMOGLOBIN S; HEMOGLOBIN A; HEMOGLOBIN BETA CHAIN;

ALLELE; ARTICLE; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GENETIC RECOMBINATION; GENETIC SELECTION; GENETIC VARIABILITY; GENOTYPE; GHANA; HAPLOTYPE; HAPLOTYPE MAP; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALARIA; PROTEIN STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; BLOOD; CASE CONTROL STUDY; ETHNIC GROUP; ETHNOLOGY; GENE FREQUENCY; GENE LOCUS; GENETICS; GENOTYPING TECHNIQUE; METHODOLOGY; MOLECULAR EVOLUTION;

ALLELES; BETA-GLOBINS; CASE-CONTROL STUDIES; ETHNIC GROUPS; EVOLUTION, MOLECULAR; GENE FREQUENCY; GENETIC LOCI; GENOTYPING TECHNIQUES; GHANA; HAPLOTYPES; HEMOGLOBIN A; HEMOGLOBIN C; HEMOGLOBIN, SICKLE; HUMANS; MALARIA; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC;

EID: 84859594502     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034565     Document Type: Article

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