Domesticated Cats with Active Mycobacteria Infections have Low Serum Vitamin D (25(OH)D) Concentrations

Transboundary and Emerging Diseases

Volumn 59, Issue 3, 2012, Pages 279-281

  Lalor, S M ^a   Mellanby, R J ^a   Friend, E J ^b   Bowlt, K L ^b   Berry, J ^c   Gunn Moore, D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Cats; Mycobacterium; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; DRUG DERIVATIVE; VITAMIN D;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CAT; CAT DISEASE; MYCOBACTERIOSIS;

ANIMALS; CAT DISEASES; CATS; MYCOBACTERIUM INFECTIONS; VITAMIN D;

CORYNEBACTERINEAE; MYCOBACTERIUM;

EID: 84859566168     PISSN: 18651674     EISSN: 18651682     Source Type: Journal    
DOI: 10.1111/j.1865-1682.2011.01265.x     Document Type: Article

References (12)

1. Anand, S. P., and P. Selvaraj, 2009: Effect of 1, 25 dihydroxyvitamin D3 on matrix metalloproteinases MMP-7, MMP-9 and the inhibitor TIMP-1 in pulmonary tuberculosis. Clin. Immunol. 33, 126-131.
2. Gow, A. G., D. J. Gow, R. Bell, J. W. Simpson, M. L. Chandler, H. Evans, J.L. Berry, M.E. Herrtage, and R.J. Mellanby, 2009: Calcium metabolism in eight dogs with hypoadrenocorticism. J. Small Anim. Pract. 50, 426-430.
3. Gunn-Moore, D. A., R. Dean, and S. Shaw, 2010: Mycobacterial disease in the cat. In. Pract. 32, 444-452.
4. Hayes, G., K. Mathews, G. Doig, S. Kruth, S. Boston, S. Nykamp, Z. Poliak, and C. Dewey, 2011: The feline acute patient physiologic and laboratory evaluation (Feline APPLE) score: a severity of illness stratification system for hospitalized cats. J. Vet. Intern. Med. 25, 26-38.
5. Liu, P. T., S. Stenger, H. Li, L. Wenzel, B. H. Tan, S.R. Krutzik, M. T. Ochoa, J. Schauber, K. Wu, C. Meinken, D. L. Kamen, M. Wagner, R. Bals, A. Steinmeyer, U. Zügel, R. L. Gallo, D. Eisenberg, M. Hewison, B.W. Hollis, J.S. Adams, B. R. Bloom, and R. L. Modlin, 2006: Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311, 1770-1773.
6. Marion, C. R., and K. P. High, 2001: Infectious Disease in the Aging: A Clinical Handbook, 2nd edn. Humana Press, New York.
7. Martineau, A. R., K. A. Wilkinson, S. M. Newton, R. A. Floto, A. W. Norman, K. Skolimowska, R. N. Davidson, O. E. Sørensen, B. Kampmann, C. J. Griffiths, and R. J. Wilkinson, 2007: IFN-gamma- and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37. J. Immunol. 178, 7190-7198.
8. Martineau, A. R., P. M. Timms, G. H. Bothamley, Y. Hanifa, K. Islam, A. P. Claxton, G. E. Packe, J. C. Moore-Gillon, M. Darmalingam, R. N. Davidson, H. J Milburn, L. V. Baker, R. D. Barker, N. J. Woodward, T. R. Venton, K. E. Barnes, C. J. Mullett, A. K. Coussens, C. M. Rutterford, C. A Mein, G. R. Davies, R. J. Wilkinson, V. Nikolayevskyy, F. A. Drobniewski, S. M. Eldridge, and C. J. Griffiths, 2011: High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Lancet 377, 242-250.
9. Nnoaham, K. E., and A. Clarke, 2008: Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int. J. Epidemiol. 37, 113-119.
10. Norman, A. W., 1998: Sunlight, season, skin pigmentation, vitamin D, and 25-hydroxyvitamin D: integral components of the vitamin D endocrine system. Am. J. Clin. Nutr. 67, 1108-1110.
11. Rhodes, S. G., T. Gruffydd-Jones, D. A. Gunn-Moore, and K. Jahans, 2008: Interferon-γ test for feline tuberculosis. Vet. Rec. 162, 453-454.
12. WHO, 2010: Global tuberculosis control 2010. Available at (accessed September 17, 2011).