E14-F55 combination in M2 protein: A putative molecular determinant responsible for swine-origin influenza A virus transmission in humans

PLoS Currents

Volumn , Issue SEP, 2009, Pages

  Pan, Chungen ^a   Jiang, Shibo ^a  

^a NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84859523427     PISSN: None     EISSN: 21573999     Source Type: Journal    
DOI: 10.1371/currents.RRN1044     Document Type: Article

References (16)

1. Chen GW, Chang SC, Mok CK et al. Genomic signatures of human versus avian influenza A viruses. Emerg. Infect. Dis. 2006; 12(9):1353-60.
2. Smith GJD, Vijaykrishna D, Bahl J et al. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 2009; 459(7250):1122-5. PubMed PMID: 19516283
3. Itoh Y, Shinya K, Kiso M et al. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature 2009; 460(7258):1021-5.
4. Garten RJ, Davis CT, Russell CA et al. Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 2009; 325(5937):197-201.
5. Chang LY, Shih SR, Shao PL, Huang DT-N, Huang LM. Novel Swine-origin Influenza Virus A (H1N1): The First Pandemic of the 21st Century. J. Formos. Med. Assoc. 2009; 108(7):526-32.
6. Miller MA, Viboud C, Balinska M, Simonsen L. The signature features of influenza pandemics--implications for policy. N. Engl. J. Med. 2009; 360(25):2595-8.
7. Dorans K. Computational tools evolve to reveal patterns in flu data. Nat Med 2009; 15(6):587.
8. Pan C, Wang G, Liao M, Zhang GH, Jiang S. High genetic and antigenic similarity between a swine H3N2 influenza A virus and a prior human influenza vaccine virus: A possible immune pressure-driven cross-species transmission. Biochem. Biophys. Res. Commun. 2009; 385(3):402-7.
9. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997; 25(24):4876-82.
10. Schnell JR, Chou JJ. Structure and mechanism of the M2 proton channel of influenza A virus. Nature 2008; 451(7178):591-5.
11. Ciampor F, Thompson CA, Grambas S, Hay AJ. Regulation of pH by the M2 protein of influenza A viruses. Virus Res. 1992; 22(3):247-58.
12. Betakova T, Hay AJ. Stability and function of the influenza A virus M2 ion channel protein is determined by both extracellular and cytoplasmic domains. Arch. Virol 2009; 154(1):147-51.
13. Schotsaert M, De FM, Fiers W, Saelens X. Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments. Expert. Rev. Vaccines. 2009; 8(4):499-508.
14. Neirynck S, Deroo T, Saelens X, Vanlandschoot P, Jou WM, Fiers W. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat. Med. 1999; 5(10):1157-63.
15. Liu W, Zou P, Ding J, Lu Y, Chen YH. Sequence comparison between the extracellular domain of M2 protein human and avian influenza A virus provides new information for bivalent influenza vaccine design. Microbes. Infect. 2005; 7(2):171-7.
16. Shaw M, Cooper L, Xu X et al. Molecular changes associated with the transmission of avian influenza a H5N1 and H9N2 viruses to humans. J Med Virol 2002; 66(1):107-14.