메뉴 건너뛰기




Volumn , Issue , 2009, Pages 257-323

Treatment with Open Eyes: Markers-Guided Chronotheranostics

Author keywords

Chronopharmacology and chronotherapy; Markers guided chronotheranostics; Transplantation applications

Indexed keywords


EID: 84859495355     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470498392.ch11     Document Type: Chapter
Times cited : (20)

References (141)
  • 4
    • 0006990327 scopus 로고
    • Resolution from a meeting of the International Society for Research on Civilization Diseases and the Environment (New SIRMCE Confederation), Brussels, Belgium, March 17-18, 1995
    • International Womb-to-Tomb Chronome Initiative Group, Fairy Tale or reality? Medtronic Chronobiology Seminar #8, April, text, 18 figures. Available at
    • Halberg F, Cornélissen G, International Womb-to-Tomb Chronome Initiative Group. Resolution from a meeting of the International Society for Research on Civilization Diseases and the Environment (New SIRMCE Confederation), Brussels, Belgium, March 17-18, 1995. Fairy Tale or reality? Medtronic Chronobiology Seminar #8, April 1995, 12 pp. text, 18 figures. Available at http://www.msi.umn.edu/Bhalberg/.
    • (1995) , pp. 12
    • Halberg, F.1    Cornélissen, G.2
  • 6
    • 0025821959 scopus 로고
    • Drug industry and chronobiology: achievements and prospects
    • Carandente A, Halberg F. Drug industry and chronobiology: achievements and prospects. Ann NY Acad Sci. 1991; 618: 484-489.
    • (1991) Ann NY Acad Sci , vol.618 , pp. 484-489
    • Carandente, A.1    Halberg, F.2
  • 7
    • 0016102773 scopus 로고
    • Protection by timing treatment according to bodily rhythms: an analogy to protection by scrubbing before surgery
    • Halberg F. Protection by timing treatment according to bodily rhythms: an analogy to protection by scrubbing before surgery. Chronobiologia. 1974; 1(suppl 1): 27-68.
    • (1974) Chronobiologia , vol.1 , Issue.SUPPL. 1 , pp. 27-68
    • Halberg, F.1
  • 8
    • 0000361937 scopus 로고
    • Circadian system phase-dependent toxicity and other effects of methopyrapone (SU-4885) in mice
    • Ertel RJ, Halberg F, Ungar F. Circadian system phase-dependent toxicity and other effects of methopyrapone (SU-4885) in mice. J Pharmacol Exp Ther. 1964; 146: 395-399.
    • (1964) J Pharmacol Exp Ther , vol.146 , pp. 395-399
    • Ertel, R.J.1    Halberg, F.2    Ungar, F.3
  • 9
    • 0027768698 scopus 로고
    • Power of Phase 0 chronobiologic trials at different signal-to-noise ratios and sample sizes
    • Bingham C, Cornélissen G, Halberg F. Power of Phase 0 chronobiologic trials at different signal-to-noise ratios and sample sizes. Chronobiologia. 1993; 20: 179-190.
    • (1993) Chronobiologia , vol.20 , pp. 179-190
    • Bingham, C.1    Cornélissen, G.2    Halberg, F.3
  • 10
    • 25044461229 scopus 로고
    • Illustrating power of costeffective ''Phase 0'' chronobiologic trials in endocrinology, psychiatry and oncology
    • In: Cornélissen G, Halberg E, Bakken E, Delmore P, Halberg F, eds. Toward Phase Zero Preclinical and Clinical Trials: Chronobiologic Designs and Illustrative Applications. University of Minnesota Medtronic Chronobiology Seminar Series #6, September
    • Cornélissen G, Bingham C, Wilson D, Halberg F. Illustrating power of costeffective ''Phase 0'' chronobiologic trials in endocrinology, psychiatry and oncology. In: Cornélissen G, Halberg E, Bakken E, Delmore P, Halberg F, eds. Toward Phase Zero Preclinical and Clinical Trials: Chronobiologic Designs and Illustrative Applications. University of Minnesota Medtronic Chronobiology Seminar Series #6, September 1992, pp 138-181.
    • (1992) , pp. 138-181
    • Cornélissen, G.1    Bingham, C.2    Wilson, D.3    Halberg, F.4
  • 12
    • 0003752275 scopus 로고
    • Chronodiagnosis and Chronotherapy of Cardiovascular Diseases
    • 2nd ed. Translation into English from Russian. Moscow: Medicina
    • Zaslavskaya RM. Chronodiagnosis and Chronotherapy of Cardiovascular Diseases, 2nd ed. Translation into English from Russian. Moscow: Medicina; 1993.
    • (1993)
    • Zaslavskaya, R.M.1
  • 13
    • 0000248041 scopus 로고
    • Chronobiology, radiobiology and steps toward the timing of cancer radiotherapy
    • In: Kaiser H, ed. Cancer Growth and Progression, vol 9, chap 19. Dordrecht: Kluwer Academic Publishers
    • Halberg F, Halberg J, Halberg E, Halberg F. Chronobiology, radiobiology and steps toward the timing of cancer radiotherapy. In: Kaiser H, ed. Cancer Growth and Progression, vol 9, chap 19. Dordrecht: Kluwer Academic Publishers; 1989: 227-253.
    • (1989) , pp. 227-253
    • Halberg, F.1    Halberg, J.2    Halberg, E.3    Halberg, F.4
  • 16
    • 0011489682 scopus 로고
    • Duality of optimal designs for model discrimination and parameter estimation
    • Fedorov VV, Khabarov V. Duality of optimal designs for model discrimination and parameter estimation. Biometrika. 1986; 73: 183-190.
    • (1986) Biometrika , vol.73 , pp. 183-190
    • Fedorov, V.V.1    Khabarov, V.2
  • 19
    • 0000464461 scopus 로고
    • Self-starting cusum charts for location and scale
    • Hawkins DM. Self-starting cusum charts for location and scale. Statistician. 1987; 36: 299-315.
    • (1987) Statistician , vol.36 , pp. 299-315
    • Hawkins, D.M.1
  • 20
    • 0031148205 scopus 로고    scopus 로고
    • Individual assessment of antihypertensive response by self-starting cumulative sums
    • Cornélissen G, Halberg F, Hawkins D, Otsuka K, Henke W. Individual assessment of antihypertensive response by self-starting cumulative sums. J Med Eng Technol. 1997; 21: 111-120.
    • (1997) J Med Eng Technol , vol.21 , pp. 111-120
    • Cornélissen, G.1    Halberg, F.2    Hawkins, D.3    Otsuka, K.4    Henke, W.5
  • 21
    • 8544268430 scopus 로고
    • Graphic monitoring of seizure incidence changes in epileptic patients
    • Johnson EA, Haus E, Halberg F, Wadsworth GL. Graphic monitoring of seizure incidence changes in epileptic patients. Minn Med. 1959; 42: 1250-1257.
    • (1959) Minn Med , vol.42 , pp. 1250-1257
    • Johnson, E.A.1    Haus, E.2    Halberg, F.3    Wadsworth, G.L.4
  • 22
    • 70449325125 scopus 로고
    • Temporal coordination of physiologic function
    • Halberg F. Temporal coordination of physiologic function. Cold Spring Harb Symp Quant Biol. 1960; 25: 289-310.
    • (1960) Cold Spring Harb Symp Quant Biol , vol.25 , pp. 289-310
    • Halberg, F.1
  • 23
    • 0043110561 scopus 로고
    • Biological as well as physical parameters relate to radiology
    • Guest Lecture, Proceedings of the 30th Annual Congress Radiology, January, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
    • Halberg F. Biological as well as physical parameters relate to radiology. Guest Lecture, Proceedings of the 30th Annual Congress Radiology, January 1977, Post-Graduate Institute of Medical Education and Research, Chandigarh, India.
    • (1977)
    • Halberg, F.1
  • 24
    • 33846049655 scopus 로고    scopus 로고
    • Cancer chronomics I: origins of timed cancer treatment: early marker rhythm-guided individualized chronochemotherapy
    • Halberg F, Prem K, Halberg F, Norman C, Cornélissen G. Cancer chronomics I: origins of timed cancer treatment: early marker rhythm-guided individualized chronochemotherapy. J Exp Ther Oncol. 2006; 6: 55-61.
    • (2006) J Exp Ther Oncol , vol.6 , pp. 55-61
    • Halberg, F.1    Prem, K.2    Halberg, F.3    Norman, C.4    Cornélissen, G.5
  • 27
    • 0026784078 scopus 로고
    • From experimental units to unique experiments: chronobiologic pilots complement large trials
    • Halberg F, Cornélissen G, Bingham C, Fujii S, Halberg E. From experimental units to unique experiments: chronobiologic pilots complement large trials. In vivo. 1992; 6: 403-428.
    • (1992) In vivo , vol.6 , pp. 403-428
    • Halberg, F.1    Cornélissen, G.2    Bingham, C.3    Fujii, S.4    Halberg, E.5
  • 28
    • 0003126733 scopus 로고
    • Introduction to Chronobiology. Medtronic Chronobiology Seminar #7
    • April, (Library of Congress Catalog Card #94-060580). Available at
    • Cornélissen G, Halberg F. Introduction to Chronobiology. Medtronic Chronobiology Seminar #7, April 1994. (Library of Congress Catalog Card #94-060580). Available at http://www.msi.umn.edu/Bhalberg.
    • (1994)
    • Cornélissen, G.1    Halberg, F.2
  • 36
    • 0025012539 scopus 로고
    • Ovarian cancer: relationship between in vitro chromosensitivity and clinical response
    • Carenza L, Villani C, Rulli G, Labi FL, Prosperi Port R. Ovarian cancer: relationship between in vitro chromosensitivity and clinical response. Gynecol Oncol. 1990; 36: 13-18.
    • (1990) Gynecol Oncol , vol.36 , pp. 13-18
    • Carenza, L.1    Villani, C.2    Rulli, G.3    Labi, F.L.4    Prosperi Port, R.5
  • 38
    • 0039276846 scopus 로고    scopus 로고
    • A multicenter evaluation of intensified, ambulatory, chronomodulated chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin as initial treatment of patients with metastatic colorectal carcinoma. International Organization for Cancer Chronotherapy
    • Levi F, Zidani R, Brienza S, Dogliotti L, Perpoint B, Rotarski M, Letourneau Y, Llory JF, Chollet P, Le Rol A, Focan C. A multicenter evaluation of intensified, ambulatory, chronomodulated chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin as initial treatment of patients with metastatic colorectal carcinoma. International Organization for Cancer Chronotherapy. Cancer. 1999; 85: 2532-2540.
    • (1999) Cancer , vol.85 , pp. 2532-2540
    • Levi, F.1    Zidani, R.2    Brienza, S.3    Dogliotti, L.4    Perpoint, B.5    Rotarski, M.6    Letourneau, Y.7    Llory, J.F.8    Chollet, P.9    Le Rol, A.10    Focan, C.11
  • 41
    • 0021077124 scopus 로고
    • The clinical application of chronobiology to oncology
    • Hrushesky WJM. The clinical application of chronobiology to oncology. Am J Anat. 1983; 168: 519-542.
    • (1983) Am J Anat , vol.168 , pp. 519-542
    • Hrushesky, W.J.M.1
  • 42
    • 0345453271 scopus 로고
    • Automatic chronotherapy: an integral part of the future of medicine
    • In: Hekkens WTJM, Kerkhof GA, Rietveld WJ, eds. Trends in Chronobiology. Oxford, UK: Pergamon Press
    • Hrushesky WJM. Automatic chronotherapy: an integral part of the future of medicine. In: Hekkens WTJM, Kerkhof GA, Rietveld WJ, eds. Trends in Chronobiology. Oxford, UK: Pergamon Press; 1988: 281-293.
    • (1988) , pp. 281-293
    • Hrushesky, W.J.M.1
  • 43
    • 0344591028 scopus 로고
    • The chronobiologic pilot study with special reference to cancer research: Is chronobiology or, rather, its neglect wasteful?
    • In: Kaiser H, ed. Cancer Growth and Progression, vol 9. chap 9. Dordrecht: Kluwer Academic Publishers;
    • Cornélissen G, Halberg F. The chronobiologic pilot study with special reference to cancer research: Is chronobiology or, rather, its neglect wasteful? In: Kaiser H, ed. Cancer Growth and Progression, vol 9. chap 9. Dordrecht: Kluwer Academic Publishers; 1989: 103-133.
    • (1989) , pp. 103-133
    • Cornélissen, G.1    Halberg, F.2
  • 44
    • 0027731895 scopus 로고
    • A lady and chronobiology
    • Kennedy BJ. A lady and chronobiology. Chronobiologia. 1993; 20: 139-144.
    • (1993) Chronobiologia , vol.20 , pp. 139-144
    • Kennedy, B.J.1
  • 45
    • 0029112909 scopus 로고
    • X-irradiation chronosensitivity and circadian rhythmic proliferation in healthy and sarcomacarrying rats' bone marrow
    • Blank MA, Gushchin VA, Halberg F, Portela A, Cornélissen G. X-irradiation chronosensitivity and circadian rhythmic proliferation in healthy and sarcomacarrying rats' bone marrow. In Vivo. 1995; 9: 395-400.
    • (1995) In Vivo , vol.9 , pp. 395-400
    • Blank, M.A.1    Gushchin, V.A.2    Halberg, F.3    Portela, A.4    Cornélissen, G.5
  • 46
    • 78650247038 scopus 로고    scopus 로고
    • Chronometaanalysis: magnetic storm associated with a reduction in circadian amplitude of rhythm in corneal cell division
    • In: International Conference on the Frontiers of Biomedical Science: Chronobiology, Chengdu, China, September 24-26
    • Halberg F, Cornélissen G, Schwartzkopff O, Katinas GS, Chibisov SM, Khalitskaya EV, Mitsutake G, Otsuka K, Scheving LA, Bakken EE. Chronometaanalysis: magnetic storm associated with a reduction in circadian amplitude of rhythm in corneal cell division. In: International Conference on the Frontiers of Biomedical Science: Chronobiology, Chengdu, China, September 24-26, 2006, pp 40-42.
    • (2006) , pp. 40-42
    • Halberg, F.1    Cornélissen, G.2    Schwartzkopff, O.3    Katinas, G.S.4    Chibisov, S.M.5    Khalitskaya, E.V.6    Mitsutake, G.7    Otsuka, K.8    Scheving, L.A.9    Bakken, E.E.10
  • 47
    • 5644223297 scopus 로고    scopus 로고
    • The hemodepressive effect of irradiation in humans
    • Blank MA, Blank OA, Duke VA. The hemodepressive effect of irradiation in humans. Dokl Biol Sci. 2003; 393: 424-426.
    • (2003) Dokl Biol Sci , vol.393 , pp. 424-426
    • Blank, M.A.1    Blank, O.A.2    Duke, V.A.3
  • 48
    • 27744502968 scopus 로고    scopus 로고
    • Influence of geomagnetic activity on mustophoran hematotoxicity
    • Blank MA, Blank OA, Gershanovich ML. Influence of geomagnetic activity on mustophoran hematotoxicity. Dokl Biol Sci. 2005; 404: 835-838.
    • (2005) Dokl Biol Sci , vol.404 , pp. 835-838
    • Blank, M.A.1    Blank, O.A.2    Gershanovich, M.L.3
  • 49
    • 9844229232 scopus 로고
    • Toward Chronopharmacology
    • New York: Pergamon Press
    • Takahashi R, Halberg F, Walker C, eds. Toward Chronopharmacology. New York: Pergamon Press; 1982 .
    • (1982)
    • Takahashi, R.1    Halberg, F.2    Walker, C.3
  • 50
    • 0009919690 scopus 로고
    • Chronobioavailability of three erythromycin test preparations assessed by each of four indices: time to peak, peak, nadir and area
    • Di Santo A, Chodos D, Halberg F. Chronobioavailability of three erythromycin test preparations assessed by each of four indices: time to peak, peak, nadir and area. Chronobiologia. 1975; 2(suppl 1): 17.
    • (1975) Chronobiologia , vol.2 , Issue.SUPPL. 1 , pp. 17
    • Di Santo, A.1    Chodos, D.2    Halberg, F.3
  • 51
    • 0019783097 scopus 로고
    • Cyclosporin A overview
    • Morris PJ. Cyclosporin A overview. Transplantation. 1981; 32: 349-354.
    • (1981) Transplantation , vol.32 , pp. 349-354
    • Morris, P.J.1
  • 56
    • 0022648584 scopus 로고
    • Organ transplantation and broader chronotherapy with implantable pump and computer programs for marker rhythm assessment
    • Cavallini M, Halberg F, Cornélissen G, Enrichens F, Margarit C. Organ transplantation and broader chronotherapy with implantable pump and computer programs for marker rhythm assessment. J Control Release. 1986; 3: 3-13.
    • (1986) J Control Release , vol.3 , pp. 3-13
    • Cavallini, M.1    Halberg, F.2    Cornélissen, G.3    Enrichens, F.4    Margarit, C.5
  • 57
    • 84914355775 scopus 로고
    • Circaseptan (about 7-day) rhythm in human kidney allograft rejection in different geographic locations
    • In: Reinberg A, Halberg F, eds. Chronopharmacology, Proceedings of the Satellite Symposium of the 7th International Congress on Pharmacology, Paris 1978. New York: Pergamon Press
    • DeVecchi A, Carandente F, Fryd DS, Halberg F, Sutherland DE, Howard RJ, Simmons RL, Najarian JS. Circaseptan (about 7-day) rhythm in human kidney allograft rejection in different geographic locations. In: Reinberg A, Halberg F, eds. Chronopharmacology, Proceedings of the Satellite Symposium of the 7th International Congress on Pharmacology, Paris 1978. New York: Pergamon Press; 1979: 193-202.
    • (1979) , pp. 193-202
    • DeVecchi, A.1    Carandente, F.2    Fryd, D.S.3    Halberg, F.4    Sutherland, D.E.5    Howard, R.J.6    Simmons, R.L.7    Najarian, J.S.8
  • 58
  • 60
    • 0018886401 scopus 로고
    • Chronobiologic study design in everyday life, clinic and laboratory
    • Halberg E, Halberg F. Chronobiologic study design in everyday life, clinic and laboratory. Chronobiologia. 1980; 7: 95-120.
    • (1980) Chronobiologia , vol.7 , pp. 95-120
    • Halberg, E.1    Halberg, F.2
  • 63
    • 0037185446 scopus 로고    scopus 로고
    • Reflections on hypertension control rates: a message from the director of the National Heart, Lung, and Blood Institute
    • Lenfant C. Reflections on hypertension control rates: a message from the director of the National Heart, Lung, and Blood Institute. Arch Intern Med. 2002; 162: 131-132.
    • (2002) Arch Intern Med , vol.162 , pp. 131-132
    • Lenfant, C.1
  • 64
    • 0030021813 scopus 로고    scopus 로고
    • Office, nurse, basal and ambulatory blood pressure as predictors of hypertensive target organ damage in male and female patients
    • Veerman DP, de Blok K, Elemarre BJ, van Montfrans GA. Office, nurse, basal and ambulatory blood pressure as predictors of hypertensive target organ damage in male and female patients. J Hum Hypertens. 1996; 10: 9-15.
    • (1996) J Hum Hypertens , vol.10 , pp. 9-15
    • Veerman, D.P.1    De Blok, K.2    Elemarre, B.J.3    Van Montfrans, G.A.4
  • 65
    • 0029829191 scopus 로고    scopus 로고
    • Impeachment of casual blood pressure measurements and the fixed limits for their interpretation and chronobiologic recommendations
    • Cornélissen G, Halberg F. Impeachment of casual blood pressure measurements and the fixed limits for their interpretation and chronobiologic recommendations. Ann NY Acad Sci. 1996; 783: 24-46.
    • (1996) Ann NY Acad Sci , vol.783 , pp. 24-46
    • Cornélissen, G.1    Halberg, F.2
  • 66
    • 0003156992 scopus 로고
    • Blood pressure and heart rate chronome mapping: a complement to the human genome initiative
    • In: Otsuka K, Cornélissen G, Halberg F, eds. Chronocardiology and Chronomedicine: Humans in Time and Cosmos. Tokyo: Life Science Publishing
    • Cornélissen G, Otsuka K, Halberg F. Blood pressure and heart rate chronome mapping: a complement to the human genome initiative. In: Otsuka K, Cornélissen G, Halberg F, eds. Chronocardiology and Chronomedicine: Humans in Time and Cosmos. Tokyo: Life Science Publishing; 1993: 16-48.
    • (1993) , pp. 16-48
    • Cornélissen, G.1    Otsuka, K.2    Halberg, F.3
  • 67
    • 0020739818 scopus 로고
    • Construction of rhythm-specified reference intervals and regions, with emphasis on ''hybrid'' data, illustrated for plasma cortisol
    • Nelson W, Cornélissen G, Hinkley D, Bingham C, Halberg F. Construction of rhythm-specified reference intervals and regions, with emphasis on ''hybrid'' data, illustrated for plasma cortisol. Chronobiologia. 1983; 10: 179-193.
    • (1983) Chronobiologia , vol.10 , pp. 179-193
    • Nelson, W.1    Cornélissen, G.2    Hinkley, D.3    Bingham, C.4    Halberg, F.5
  • 68
    • 0021751353 scopus 로고
    • Cardiovascular reference data base for recognizing circadian mesor- and amplitude-hypertension in apparently healthy men
    • Halberg F, Drayer JIM, Cornélissen G, Weber MA. Cardiovascular reference data base for recognizing circadian mesor- and amplitude-hypertension in apparently healthy men. Chronobiologia. 1984; 11: 275-298.
    • (1984) Chronobiologia , vol.11 , pp. 275-298
    • Halberg, F.1    Drayer, J.I.M.2    Cornélissen, G.3    Weber, M.A.4
  • 69
    • 0014440909 scopus 로고
    • Chronobiology
    • Halberg F. Chronobiology. Annu Rev Physiol. 1969; 31: 675-725.
    • (1969) Annu Rev Physiol , vol.31 , pp. 675-725
    • Halberg, F.1
  • 70
    • 0000900308 scopus 로고
    • Chronobiology: methodological problems
    • Halberg F. Chronobiology: methodological problems. Acta Med Rom. 1980; 18: 399-440.
    • (1980) Acta Med Rom , vol.18 , pp. 399-440
    • Halberg, F.1
  • 71
    • 27744463398 scopus 로고    scopus 로고
    • Chronomedicine
    • In: Armitage P, Colton T, eds. Encyclopedia of Biostatistics, 2nd ed. Chichester, UK: John Wiley & Sons Ltd
    • Cornélissen G, Halberg F. Chronomedicine In: Armitage P, Colton T, eds. Encyclopedia of Biostatistics, 2nd ed. Chichester, UK: John Wiley & Sons Ltd; 2005: 796-812.
    • (2005) , pp. 796-812
    • Cornélissen, G.1    Halberg, F.2
  • 73
    • 0002353795 scopus 로고
    • Chronobiologic blood pressure assessment from womb to tomb
    • In: Touitou Y, Haus E, eds. Biological Rhythms in Clinical and Laboratory Medicine. Berlin: Springer-Verlag
    • Cornélissen G, Haus E, Halberg F. Chronobiologic blood pressure assessment from womb to tomb. In: Touitou Y, Haus E, eds. Biological Rhythms in Clinical and Laboratory Medicine. Berlin: Springer-Verlag; 1992: 428-452.
    • (1992) , pp. 428-452
    • Cornélissen, G.1    Haus, E.2    Halberg, F.3
  • 74
    • 0026090654 scopus 로고
    • Analysis of ambulatory blood pressure data in antihypertensive drug trials
    • White WB. Analysis of ambulatory blood pressure data in antihypertensive drug trials. J Hypertens. 1991; 9(suppl 1): S27-S32.
    • (1991) J Hypertens. , vol.9 , Issue.SUPPL. 1
    • White, W.B.1
  • 75
    • 0025064672 scopus 로고
    • National High Blood Pressure Education Program Coordinating Committee Working Group Report on Ambulatory Blood Pressure Monitoring
    • National High Blood Pressure Education Program Coordinating Committee Working Group Report on Ambulatory Blood Pressure Monitoring. Arch Intern Med. 1990; 150: 2270-2280.
    • (1990) Arch Intern Med. , vol.150 , pp. 2270-2280
  • 78
    • 0012106933 scopus 로고    scopus 로고
    • Blood pressure and heart rate dynamics during pregnancy and early extra-uterine life: methodology for a chrononeonatology
    • In: Halberg F, Kenner T, Fiser B, eds. Proceedings, Symposium: The Importance of Chronobiology in Diagnosing and Therapy of Internal Diseases. Faculty of Medicine, Masaryk University, Brno, Czech Republic, January 10-13, 2002. Brno: Masaryk University
    • Cornélissen G, Siegelova J, Halberg F. Blood pressure and heart rate dynamics during pregnancy and early extra-uterine life: methodology for a chrononeonatology. In: Halberg F, Kenner T, Fiser B, eds. Proceedings, Symposium: The Importance of Chronobiology in Diagnosing and Therapy of Internal Diseases. Faculty of Medicine, Masaryk University, Brno, Czech Republic, January 10-13, 2002. Brno: Masaryk University; 2002: 58-96.
    • (2002) , pp. 58-96
    • Cornélissen, G.1    Siegelova, J.2    Halberg, F.3
  • 79
    • 31444436871 scopus 로고    scopus 로고
    • Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease
    • Kshirsagar AV, Carpenter M, Bang H, Wyatt SB, Colindres RE. Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease. Am J Med. 2006; 119: 133-141.
    • (2006) Am J Med , vol.119 , pp. 133-141
    • Kshirsagar, A.V.1    Carpenter, M.2    Bang, H.3    Wyatt, S.B.4    Colindres, R.E.5
  • 80
    • 1842734432 scopus 로고    scopus 로고
    • Definition und Klassifikation der Hypertonie
    • Deutsche Hochdruckliga e.V. (DHL) und Deutsche Hypertoniegesellschaft (DHL/DHG). Leitlinien zur Hypertonie. Available at
    • Magometschnigg D. Definition und Klassifikation der Hypertonie. J Hyperton. 2004; 8: 12-13. Deutsche Hochdruckliga e.V. (DHL) und Deutsche Hypertoniegesellschaft (DHL/DHG). Leitlinien zur Hypertonie. Available at http://www.paritaet.org/RR-Liga/Hypertonie-Leitlinien05.pdf.
    • (2004) J Hyperton. , vol.8 , pp. 12-13
    • Magometschnigg, D.1
  • 81
    • 84889374226 scopus 로고    scopus 로고
    • Mayo Clinic Guide to Self-Care: Answers for Everyday Health Problems
    • Hagen P, ed. Mayo Clinic Guide to Self-Care: Answers for Everyday Health Problems. Rochester, MN: Mayo Clinic; 2003: 180-181.
    • (2003) Rochester, MN: Mayo Clinic , pp. 180-181
    • Hagen, P.1
  • 83
    • 0031885332 scopus 로고    scopus 로고
    • Hypertension in women: current understanding of gender differences
    • Hayes SN, Taler SJ. Hypertension in women: current understanding of gender differences. Mayo Clin Proc. 1998; 73: 157-165.
    • (1998) Mayo Clin Proc , vol.73 , pp. 157-165
    • Hayes, S.N.1    Taler, S.J.2
  • 84
    • 0035207735 scopus 로고    scopus 로고
    • Systolic Hypertension in Europe Trial Investigators. Risk and benefit of treatment of isolated hypertension in the elderly: evidence from the Systolic Hypertension in Europe Trial
    • Celis H, Fagard RH, Staessen JA, Thijs L. Systolic Hypertension in Europe Trial Investigators. Risk and benefit of treatment of isolated hypertension in the elderly: evidence from the Systolic Hypertension in Europe Trial. Curr Opin Cardiol. 2001; 16: 342-348.
    • (2001) Curr Opin Cardiol , vol.16 , pp. 342-348
    • Celis, H.1    Fagard, R.H.2    Staessen, J.A.3    Thijs, L.4
  • 85
    • 0023100673 scopus 로고
    • Multicenter Post-Infarction Research Group. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction
    • Kleiger RE, Miller JP, Bigger JT, Moss AJ. Multicenter Post-Infarction Research Group. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol. 1987; 59: 256-262.
    • (1987) Am J Cardiol , vol.59 , pp. 256-262
    • Kleiger, R.E.1    Miller, J.P.2    Bigger, J.T.3    Moss, A.J.4
  • 87
    • 0030031258 scopus 로고    scopus 로고
    • Predictive value of blood pressure dipping and swinging with regard to vascular disease risk
    • Otsuka K, Cornélissen G, Halberg F. Predictive value of blood pressure dipping and swinging with regard to vascular disease risk. Clin Drug Investi. 1996; 11: 20-31.
    • (1996) Clin Drug Investi , vol.11 , pp. 20-31
    • Otsuka, K.1    Cornélissen, G.2    Halberg, F.3
  • 88
    • 1842378596 scopus 로고    scopus 로고
    • Circadian rhythmic fractal scaling of heart rate variability in health and coronary artery disease
    • Otsuka K, Cornélissen G, Halberg F. Circadian rhythmic fractal scaling of heart rate variability in health and coronary artery disease. Clin Cardiol. 1997; 20: 631-638.
    • (1997) Clin Cardiol , vol.20 , pp. 631-638
    • Otsuka, K.1    Cornélissen, G.2    Halberg, F.3
  • 89
    • 0030678578 scopus 로고    scopus 로고
    • Age, gender and fractal scaling in heart rate variability
    • Otsuka K, Cornélissen G, Halberg F. Age, gender and fractal scaling in heart rate variability. Clin Sci. 1997; 93: 299-308.
    • (1997) Clin Sci , vol.93 , pp. 299-308
    • Otsuka, K.1    Cornélissen, G.2    Halberg, F.3
  • 90
    • 0007438523 scopus 로고    scopus 로고
    • Heart rate variability measures and the autonomic nervous function
    • Otsuka K, Cornélissen G, Halberg F. Heart rate variability measures and the autonomic nervous function. Diagn Treatment. 1997; 85: 1500-1506.
    • (1997) Diagn Treatment , vol.85 , pp. 1500-1506
    • Otsuka, K.1    Cornélissen, G.2    Halberg, F.3
  • 91
    • 0031003073 scopus 로고    scopus 로고
    • Excessive circadian amplitude of blood pressure increases risk of ischemic stroke and nephropathy
    • Otsuka K, Cornélissen G, Halberg F, Oehlert G. Excessive circadian amplitude of blood pressure increases risk of ischemic stroke and nephropathy. J Med Eng Technol. 1997; 21: 23-30.
    • (1997) J Med Eng Technol , vol.21 , pp. 23-30
    • Otsuka, K.1    Cornélissen, G.2    Halberg, F.3    Oehlert, G.4
  • 93
    • 0031685798 scopus 로고    scopus 로고
    • Reversed circadian blood pressure rhythm is associated with occurrence of both fatal and nonfatal vascular events in NIDDM subjects
    • Nakano S, Fukuda M, Hotta F, Ito T, Ishii T, Kitazawa M, Nishizawa M, Kigoshi T, Uchida K. Reversed circadian blood pressure rhythm is associated with occurrence of both fatal and nonfatal vascular events in NIDDM subjects. Diabetes. 1998; 47: 1501-1506.
    • (1998) Diabetes , vol.47 , pp. 1501-1506
    • Nakano, S.1    Fukuda, M.2    Hotta, F.3    Ito, T.4    Ishii, T.5    Kitazawa, M.6    Nishizawa, M.7    Kigoshi, T.8    Uchida, K.9
  • 94
    • 27744489174 scopus 로고    scopus 로고
    • Blood pressure (BP), heart rate (HR) and non-insulin-dependent diabetes mellitus (NIDDM) chronobiology. Abstract S8-06, 3rd International Congress on Cardiovascular Disease, Taipei, Taiwan, November 26-28, 2004
    • Sanchez de la Pena S, Gonzalez C, Cornélissen G, Halberg F. Blood pressure (BP), heart rate (HR) and non-insulin-dependent diabetes mellitus (NIDDM) chronobiology. Abstract S8-06, 3rd International Congress on Cardiovascular Disease, Taipei, Taiwan, November 26-28, 2004. Int J Cardiol. 2004; 97(suppl 2): S14.
    • (2004) Int J Cardiol. , vol.97 , Issue.SUPPL. 2
    • Sanchez De La Pena, S.1    Gonzalez, C.2    Cornélissen, G.3    Halberg, F.4
  • 95
    • 33747831087 scopus 로고    scopus 로고
    • Predictive value of blood pressure variability: merits of circadian parameters versus dipping patterns
    • Cornélissen G, Chen CH, Halberg F. Predictive value of blood pressure variability: merits of circadian parameters versus dipping patterns. N Engl J Med. 2006; 355: 850.
    • (2006) N Engl J Med. , vol.355 , pp. 850
    • Cornélissen, G.1    Chen, C.H.2    Halberg, F.3
  • 101
    • 0035184504 scopus 로고    scopus 로고
    • Does overswinging provide an early warning of cardiovascular disease risk when non-dipping may fail? A metaanalysis of 2039 cases
    • Chen CH, Cornélissen G, Siegelova J, Halberg F. Does overswinging provide an early warning of cardiovascular disease risk when non-dipping may fail? A metaanalysis of 2039 cases. Scr Med. 2001; 74: 75-80.
    • (2001) Scr Med , vol.74 , pp. 75-80
    • Chen, C.H.1    Cornélissen, G.2    Siegelova, J.3    Halberg, F.4
  • 102
    • 0035189788 scopus 로고    scopus 로고
    • Vascular disease risk syndromes affecting both MESOR-normotensives and MESOR-hypertensives: a metaanalysis of 2039 cases
    • Cornélissen G, Chen CH, Siegelova J, Halberg F. Vascular disease risk syndromes affecting both MESOR-normotensives and MESOR-hypertensives: a metaanalysis of 2039 cases. Scr Med. 2001; 74: 81-86.
    • (2001) Scr Med , vol.74 , pp. 81-86
    • Cornélissen, G.1    Chen, C.H.2    Siegelova, J.3    Halberg, F.4
  • 104
    • 0029004874 scopus 로고
    • Spectral analysis of blood pressure and heart rate variability in evaluating cardiovascular regulation
    • Parati G, Saul JP, Di Rienzo M, Mancia G. Spectral analysis of blood pressure and heart rate variability in evaluating cardiovascular regulation. Hypertension. 1995; 25: 1276-1286.
    • (1995) Hypertension , vol.25 , pp. 1276-1286
    • Parati, G.1    Saul, J.P.2    Di Rienzo, M.3    Mancia, G.4
  • 107
    • 22144433916 scopus 로고
    • Clinical aspects of blood pressure autorhythmometry
    • In: Scheving LE, Halberg F, Pauly JE, eds. Chronobiology, Proceedings of the International Society for the Study of Biological Rhythms, Little Rock, Arkansas. Tokyo: Igaku Shoin Ltd
    • Levine H, Halberg F. Clinical aspects of blood pressure autorhythmometry. In: Scheving LE, Halberg F, Pauly JE, eds. Chronobiology, Proceedings of the International Society for the Study of Biological Rhythms, Little Rock, Arkansas. Tokyo: Igaku Shoin Ltd; 1974 406-414.
    • (1974) , pp. 406-414
    • Levine, H.1    Halberg, F.2
  • 108
    • 84889456187 scopus 로고
    • Effectiveness of chronotherapy of hypertensive patients with hypotensive drugs
    • In: Tarquini B, ed. Social Diseases and Chronobiology. Bologna: Esculapio
    • Zaslavskaya RM, Varshitsky MG, Teibloom MM. Effectiveness of chronotherapy of hypertensive patients with hypotensive drugs. In: Tarquini B, ed. Social Diseases and Chronobiology. Bologna: Esculapio; 1987: 373-380.
    • (1987) , pp. 373-380
    • Zaslavskaya, R.M.1    Varshitsky, M.G.2    Teibloom, M.M.3
  • 110
    • 0026355431 scopus 로고
    • International Womb-to-Tomb Chronome Study Group. Prophylactic aspirin treatment: the merits of timing
    • Cornélissen G, Halberg F, Prikryl P, Dankova E, Siegelova J, Dusek J. International Womb-to-Tomb Chronome Study Group. Prophylactic aspirin treatment: the merits of timing. JAMA. 1991; 266: 3128-3129.
    • (1991) JAMA , vol.266 , pp. 3128-3129
    • Cornélissen, G.1    Halberg, F.2    Prikryl, P.3    Dankova, E.4    Siegelova, J.5    Dusek, J.6
  • 112
  • 113
    • 0023245236 scopus 로고
    • Day and night aspirin-induced gastric mucosal damage and protection by ranitidine in man
    • Moore JG, Goo RH. Day and night aspirin-induced gastric mucosal damage and protection by ranitidine in man. Chronobiology Int. 1987; 4: 111-116.
    • (1987) Chronobiology Int , vol.4 , pp. 111-116
    • Moore, J.G.1    Goo, R.H.2
  • 114
    • 84889428989 scopus 로고
    • Daily variation of acute gastric mucosal injury after high- and low-dose acetylsalicylic acid
    • Nold G, Drossard W, Lehmann K, Lemmer B. Daily variation of acute gastric mucosal injury after high- and low-dose acetylsalicylic acid. Biol Rhythm Res. 1995; 26: 428.
    • (1995) Biol Rhythm Res. , vol.26 , pp. 428
    • Nold, G.1    Drossard, W.2    Lehmann, K.3    Lemmer, B.4
  • 115
    • 34948868491 scopus 로고
    • Gastric mucosal lesions after morning versus evening application of 75 mg or 1000 mg acetylsalicylic acid (ASA)
    • Nold G, Drossard W, Lehmann K, Lemmer B. Gastric mucosal lesions after morning versus evening application of 75 mg or 1000 mg acetylsalicylic acid (ASA). Naunyn-Schmiedeberg's Arch Pharmacol. 1995; 351: R17.
    • (1995) Naunyn-Schmiedeberg's Arch Pharmacol , vol.351
    • Nold, G.1    Drossard, W.2    Lehmann, K.3    Lemmer, B.4
  • 117
    • 84885621833 scopus 로고    scopus 로고
    • Coenzyme-Q10 effect on blood pressure variability assessed with a chronobiological study design
    • In: Noninvasive Methods in Cardiology, Brno, Czech Republic, September 14, 2005. Brno: Masaryk University
    • Cornélissen G, Halberg F, Schwartzkopff O, Gvozdjakova A, Siegelova J, Fiser B, Dusek J, Mifkova L, Chopra RK, Singh RB. Coenzyme-Q10 effect on blood pressure variability assessed with a chronobiological study design. In: Noninvasive Methods in Cardiology, Brno, Czech Republic, September 14, 2005. Brno: Masaryk University; 2005: 10.
    • (2005) , pp. 10
    • Cornélissen, G.1    Halberg, F.2    Schwartzkopff, O.3    Gvozdjakova, A.4    Siegelova, J.5    Fiser, B.6    Dusek, J.7    Mifkova, L.8    Chopra, R.K.9    Singh, R.B.10
  • 119
    • 0031769003 scopus 로고    scopus 로고
    • Comparison of active treatment and placebo for older Chinese patients with isolated systolic hypertension
    • for the Systolic Hypertension in China (Sys-China) Collaborative Group
    • Liu L, Wang JG, Gong L, Liu G, Staessen JA, for the Systolic Hypertension in China (Sys-China) Collaborative Group. Comparison of active treatment and placebo for older Chinese patients with isolated systolic hypertension. J Hypertens. 1998; 16: 823-1829.
    • (1998) J Hypertens , vol.16 , pp. 823-1829
    • Liu, L.1    Wang, J.G.2    Gong, L.3    Liu, G.4    Staessen, J.A.5
  • 120
    • 10644229466 scopus 로고    scopus 로고
    • Impact of circadian amplitude and chronotherapy: relevance to prevention and treatment of stroke
    • Shinagawa M, Kubo Y, Otsuka K, Ohkawa S, Cornélissen G, Halberg F. Impact of circadian amplitude and chronotherapy: relevance to prevention and treatment of stroke. Biomed Pharmacother. 2001; 55(suppl 1): 125-132.
    • (2001) Biomed Pharmacother , vol.55 , Issue.SUPPL. 1 , pp. 125-132
    • Shinagawa, M.1    Kubo, Y.2    Otsuka, K.3    Ohkawa, S.4    Cornélissen, G.5    Halberg, F.6
  • 126
    • 0032588768 scopus 로고    scopus 로고
    • Overview of the use of CoQ10 in cardiovascular disease
    • Langsjoen PH, Langsjoen AM. Overview of the use of CoQ10 in cardiovascular disease. Biofactors. 1999; 9: 273-284.
    • (1999) Biofactors , vol.9 , pp. 273-284
    • Langsjoen, P.H.1    Langsjoen, A.M.2
  • 128
    • 32744469882 scopus 로고    scopus 로고
    • Different effects of lercanidipine and felodipine on circadian blood pressure and heart rate among hypertensive patients. Abstract 15, HK College of Cardiology, 12th Annual Science Congress
    • Fok BSP, Cornélissen G, Halberg F, Chu TTW, Thomas GN, Tomlinson B. Different effects of lercanidipine and felodipine on circadian blood pressure and heart rate among hypertensive patients. Abstract 15, HK College of Cardiology, 12th Annual Science Congress. J Hong Kong Coll Cardiol. 2004; 12: 33.
    • (2004) J Hong Kong Coll Cardiol. , vol.12 , pp. 33
    • Fok, B.S.P.1    Cornélissen, G.2    Halberg, F.3    Chu, T.T.W.4    Thomas, G.N.5    Tomlinson, B.6
  • 130
    • 0026717142 scopus 로고
    • Usefulness of circadian amplitude of blood pressure in predicting hypertensive cardiac involvement
    • Kumagai Y, Shiga T, Sunaga K, Cornélissen G, Ebihara A, Halberg F. Usefulness of circadian amplitude of blood pressure in predicting hypertensive cardiac involvement. Chronobiologia. 1992; 19: 43-58.
    • (1992) Chronobiologia , vol.19 , pp. 43-58
    • Kumagai, Y.1    Shiga, T.2    Sunaga, K.3    Cornélissen, G.4    Ebihara, A.5    Halberg, F.6
  • 131
    • 0031462437 scopus 로고    scopus 로고
    • Incidence pattern and treatment of a clinical entity, overswinging or circadian hyperamplitudetension (CHAT)
    • Watanabe Y, Cornélissen G, Halberg F, Bingham C, Siegelova J, Otsuka K, Kikuchi T. Incidence pattern and treatment of a clinical entity, overswinging or circadian hyperamplitudetension (CHAT). Scr Medica. 1997; 70: 245-261.
    • (1997) Scr Medica , vol.70 , pp. 245-261
    • Watanabe, Y.1    Cornélissen, G.2    Halberg, F.3    Bingham, C.4    Siegelova, J.5    Otsuka, K.6    Kikuchi, T.7
  • 133
    • 0036850750 scopus 로고    scopus 로고
    • Rapid molecular theranostics in infectious diseases
    • Picard FJ, Bergeron MG. Rapid molecular theranostics in infectious diseases. Drug Discov Today. 2002; 7: 1092-1101.
    • (2002) Drug Discov Today , vol.7 , pp. 1092-1101
    • Picard, F.J.1    Bergeron, M.G.2
  • 135
    • 31044441473 scopus 로고    scopus 로고
    • Pharmacogenetics and the concept of individualized medicine
    • Shastry BS. Pharmacogenetics and the concept of individualized medicine. Pharmacogenomics J. 2006; 6: 16-21.
    • (2006) Pharmacogenomics J , vol.6 , pp. 16-21
    • Shastry, B.S.1
  • 136
    • 26244435220 scopus 로고    scopus 로고
    • Evolution of biomarkers: drug discovery to personalized medicine
    • Mukhtar M. Evolution of biomarkers: drug discovery to personalized medicine. Drug Discov Today. 2005; 10: 1216-1218.
    • (2005) Drug Discov Today , vol.10 , pp. 1216-1218
    • Mukhtar, M.1
  • 137
    • 33845927942 scopus 로고    scopus 로고
    • When averages hide individual differences in clinical trials
    • Kent D, Hayward R. When averages hide individual differences in clinical trials. Am Scientist. 2007; 95: 60-68.
    • (2007) Am Scientist , vol.95 , pp. 60-68
    • Kent, D.1    Hayward, R.2
  • 138
    • 0142163617 scopus 로고
    • Some correlations between chemical structure and maximal eosinopenia in adrenalectomized and hypophysectomized mice
    • Halberg F. Some correlations between chemical structure and maximal eosinopenia in adrenalectomized and hypophysectomized mice. J Pharmacol Exp Ther. 1952; 106: 135-149.
    • (1952) J Pharmacol Exp Ther , vol.106 , pp. 135-149
    • Halberg, F.1
  • 139
    • 4243185373 scopus 로고    scopus 로고
    • One Man's Full Life
    • Minneapolis, MN: Medtronic Inc;
    • Bakken EE. One Man's Full Life. Minneapolis, MN: Medtronic Inc; 1999.
    • (1999)
    • Bakken, E.E.1
  • 140
    • 0025911203 scopus 로고
    • Temporal control of drugs
    • Bakken EE, Heruth K. Temporal control of drugs. Ann NY Acad Sci. 1991; 618: 484-489.
    • (1991) Ann NY Acad Sci , vol.618 , pp. 484-489
    • Bakken, E.E.1    Heruth, K.2
  • 141
    • 0034754281 scopus 로고    scopus 로고
    • Essays on chronomics spawned by transdisciplinary chronobiology: witness in time: Earl Elmer Bakken
    • Halberg F, Cornélissen G, Otsuka K, Katinas G, Schwartzkopff O. Essays on chronomics spawned by transdisciplinary chronobiology: witness in time: Earl Elmer Bakken. Neuroendocrinol Lett. 2001; 22: 359-384.
    • (2001) Neuroendocrinol Lett , vol.22 , pp. 359-384
    • Halberg, F.1    Cornélissen, G.2    Otsuka, K.3    Katinas, G.4    Schwartzkopff, O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.