메뉴 건너뛰기




Volumn 19, Issue 2, 2012, Pages 92-101

Biology of bone metastases

Author keywords

[No Author keywords available]

Indexed keywords

ATRASENTAN; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; DENOSUMAB; ENDOTHELIN 1; IBANDRONIC ACID; ODANACATIB; OSTEOCLAST DIFFERENTIATION FACTOR; PAMIDRONIC ACID; PARATHYROID HORMONE RELATED PROTEIN; PLACEBO; ZOLEDRONIC ACID;

EID: 84859455517     PISSN: 10732748     EISSN: 15262359     Source Type: Journal    
DOI: 10.1177/107327481201900203     Document Type: Review
Times cited : (90)

References (70)
  • 1
    • 0004754144 scopus 로고    scopus 로고
    • Bone metastases: Incidence and complications
    • Rubens RD, Mundy GR, eds., London: Martin Dunitz
    • Rubens RD. Bone metastases: incidence and complications. In: Rubens RD, Mundy GR, eds. Cancer and the Skeleton. London: Martin Dunitz; 2000:33-42.
    • (2000) Cancer and The Skeleton , pp. 33-42
    • Rubens, R.D.1
  • 2
    • 0042914647 scopus 로고    scopus 로고
    • Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial
    • The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
    • Rosen LS, Gordon D, Tchekmedyian S, et al. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial. The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J Clin Oncol. 2003;21(16):3150-3157.
    • (2003) J Clin Oncol , vol.21 , Issue.16 , pp. 3150-3157
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, S.3
  • 3
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer. 2003;98(8):1735-1744.
    • (2003) Cancer , vol.98 , Issue.8 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 4
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • Roodman GD. Mechanisms of bone metastasis. N Engl J Med. 2004;350(16):1655-1664.
    • (2004) N Engl J Med , vol.350 , Issue.16 , pp. 1655-1664
    • Roodman, G.D.1
  • 5
    • 38549085667 scopus 로고    scopus 로고
    • The bone microenvironment in metastasis; what is special about bone?
    • Bussard KM, Gay CV, Mastro AM. The bone microenvironment in metastasis; what is special about bone? Cancer Metastasis Rev. 2008; 27(1):41-55.
    • (2008) Cancer Metastasis Rev , vol.27 , Issue.1 , pp. 41-55
    • Bussard, K.M.1    Gay, C.V.2    Mastro, A.M.3
  • 6
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer. 2002;2(8):563-572.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    Macdonald, I.C.3
  • 7
    • 0034284054 scopus 로고    scopus 로고
    • Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4) beta(1)-integrin enhances production of osteoclast-stimulating activity
    • Michigami T, Shimizu N, Williams PJ, et al. Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4) beta(1)-integrin enhances production of osteoclast-stimulating activity. Blood. 2000;96(5):1953-1960.
    • (2000) Blood , vol.96 , Issue.5 , pp. 1953-1960
    • Michigami, T.1    Shimizu, N.2    Williams, P.J.3
  • 8
    • 1642515775 scopus 로고    scopus 로고
    • Induction of syndecan-1 expression in stromal fibroblasts promotes proliferation of human breast cancer cells
    • Maeda T, Alexander CM, Friedl A. Induction of syndecan-1 expression in stromal fibroblasts promotes proliferation of human breast cancer cells. Cancer Res. 2004;64(2):612-621.
    • (2004) Cancer Res , vol.64 , Issue.2 , pp. 612-621
    • Maeda, T.1    Alexander, C.M.2    Friedl, A.3
  • 9
    • 79952111427 scopus 로고    scopus 로고
    • Implications of bone metastases and the benefits of bone-targeted therapy
    • Lipton A. Implications of bone metastases and the benefits of bone-targeted therapy. Semin Oncol. 2010;37(suppl 2):S15-S29.
    • (2010) Semin Oncol , vol.37 , Issue.SUPPL. 2
    • Lipton, A.1
  • 10
    • 0029101805 scopus 로고
    • Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
    • Sasaki A, Boyce BF, Story B, et al. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Res. 1995;55(16):3551-3557.
    • (1995) Cancer Res , vol.55 , Issue.16 , pp. 3551-3557
    • Sasaki, A.1    Boyce, B.F.2    Story, B.3
  • 11
    • 0036682211 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer
    • Powles T, Paterson S, Kanis JA, et al. Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer. J Clin Oncol. 2002;20(15):3219-3224.
    • (2002) J Clin Oncol , vol.20 , Issue.15 , pp. 3219-3224
    • Powles, T.1    Paterson, S.2    Kanis, J.A.3
  • 12
    • 0037303203 scopus 로고    scopus 로고
    • Role of endothelin-1 in osteoblastic bone metastases
    • Guise TA, Yin JJ, Mohammad KS. Role of endothelin-1 in osteoblastic bone metastases. Cancer. 2003;97(3 suppl):779-784.
    • (2003) Cancer , vol.97 , Issue.3 SUPPL. , pp. 779-784
    • Guise, T.A.1    Yin, J.J.2    Mohammad, K.S.3
  • 13
    • 0029085123 scopus 로고
    • Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
    • Nelson JB, Hedican SP, George DJ, et al. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med. 1995;1(9):944-949.
    • (1995) Nat Med , vol.1 , Issue.9 , pp. 944-949
    • Nelson, J.B.1    Hedican, S.P.2    George, D.J.3
  • 14
    • 0036468926 scopus 로고    scopus 로고
    • Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer
    • Yi B, Williams PJ, Niewolna M, et al. Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer. Cancer Res. 2002;62(3):917-923.
    • (2002) Cancer Res , vol.62 , Issue.3 , pp. 917-923
    • Yi, B.1    Williams, P.J.2    Niewolna, M.3
  • 15
    • 13444306377 scopus 로고    scopus 로고
    • Crosstalk between cancer cells and bone microenvironment in bone metastasis
    • Yoneda T, Hiraga T. Crosstalk between cancer cells and bone microenvironment in bone metastasis. Biochem Biophys Res Commun. 2005;328(3):679-687.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.3 , pp. 679-687
    • Yoneda, T.1    Hiraga, T.2
  • 16
    • 10144241022 scopus 로고    scopus 로고
    • Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
    • Guise TA, Yin JJ, Taylor SD, et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest. 1996;98(7):1544-1549.
    • (1996) J Clin Invest , vol.98 , Issue.7 , pp. 1544-1549
    • Guise, T.A.1    Yin, J.J.2    Taylor, S.D.3
  • 17
    • 0942279599 scopus 로고    scopus 로고
    • Downregulation of osteopontin and bone sialoprotein II is related to reduced colony formation and metastasis formation of MDA-MB-231 human breast cancer cells
    • Adwan H, Bäuerle TJ, Berger MR. Downregulation of osteopontin and bone sialoprotein II is related to reduced colony formation and metastasis formation of MDA-MB-231 human breast cancer cells. Cancer Gene Ther. 2004;11(2):109-120.
    • (2004) Cancer Gene Ther , vol.11 , Issue.2 , pp. 109-120
    • Adwan, H.1    Bäuerle, T.J.2    Berger, M.R.3
  • 18
    • 40649090942 scopus 로고    scopus 로고
    • Molecular mechanisms and treatment of bone metastasis
    • Clines GA, Guise TA. Molecular mechanisms and treatment of bone metastasis. Expert Rev Mol Med. 2008;10:e7.
    • (2008) Expert Rev Mol Med , vol.e7 , pp. 10
    • Clines, G.A.1    Guise, T.A.2
  • 19
    • 12344290222 scopus 로고    scopus 로고
    • Monitoring of skeletal progression of prostate cancer by GFP imaging, X-ray, and serum OPG and PTHrP
    • Burton DW, Geller J, Yang M, et al. Monitoring of skeletal progression of prostate cancer by GFP imaging, X-ray, and serum OPG and PTHrP. Prostate. 2005;62(3):275-281.
    • (2005) Prostate , vol.62 , Issue.3 , pp. 275-281
    • Burton, D.W.1    Geller, J.2    Yang, M.3
  • 20
    • 67650431302 scopus 로고    scopus 로고
    • Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
    • Fulciniti M, Tassone P, Hideshima T, et al. Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood. 2009;114(2):371-379.
    • (2009) Blood , vol.114 , Issue.2 , pp. 371-379
    • Fulciniti, M.1    Tassone, P.2    Hideshima, T.3
  • 21
    • 19944386284 scopus 로고    scopus 로고
    • Radioisotopes for the palliation of metastatic bone cancer: A systematic review
    • Finlay IG, Mason MD, Shelley M. Radioisotopes for the palliation of metastatic bone cancer: a systematic review. Lancet Oncol. 2005;6(6):392-400.
    • (2005) Lancet Oncol , vol.6 , Issue.6 , pp. 392-400
    • Finlay, I.G.1    Mason, M.D.2    Shelley, M.3
  • 22
    • 0034922587 scopus 로고    scopus 로고
    • A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer
    • Dafermou A, Colamussi P, Giganti M, et al. A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer. Eur J Nucl Med. 2001;28(7):788-798.
    • (2001) Eur J Nucl Med , vol.28 , Issue.7 , pp. 788-798
    • Dafermou, A.1    Colamussi, P.2    Giganti, M.3
  • 23
    • 9044219839 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma
    • Myeloma Aredia Study Group
    • Berenson JR, Lichtenstein A, Porter L, et al. Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. N Engl J Med. 1996;334(8):488-493.
    • (1996) N Engl J Med , vol.334 , Issue.8 , pp. 488-493
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 24
    • 10544228130 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases
    • Protocol 19 Aredia Breast Cancer Study Group
    • Hortobagyi GN, Theriault RL, Porter L, et al. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. N Engl J Med. 1996;335(24):1785-1791.
    • (1996) N Engl J Med , vol.335 , Issue.24 , pp. 1785-1791
    • Hortobagyi, G.N.1    Theriault, R.L.2    Porter, L.3
  • 25
    • 0035463593 scopus 로고    scopus 로고
    • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: a phase III, double-blind, comparative trial. Cancer J. 2001;7(5):377-387.
    • (2001) Cancer J , vol.7 , Issue.5 , pp. 377-387
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 26
    • 0037009822 scopus 로고    scopus 로고
    • A randomized, placebocontrolled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma
    • Saad F, Gleason DM, Murray R, et al. A randomized, placebocontrolled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst. 2002;94(19):1458-1468.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.19 , pp. 1458-1468
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 27
    • 0027531814 scopus 로고
    • Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer
    • Paterson AH, Powles TJ, Kanis JA, et al. Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer. J Clin Oncol. 1993;11(1):59-65.
    • (1993) J Clin Oncol , vol.11 , Issue.1 , pp. 59-65
    • Paterson, A.H.1    Powles, T.J.2    Kanis, J.A.3
  • 28
    • 0029166436 scopus 로고
    • Effect of oral clodronate on metastatic bone pain: A double-blind, placebo-controlled study
    • Robertson AG, Reed NS, Ralston SH. Effect of oral clodronate on metastatic bone pain: a double-blind, placebo-controlled study. J Clin Oncol. 1995;13(9):2427-2430.
    • (1995) J Clin Oncol , vol.13 , Issue.9 , pp. 2427-2430
    • Robertson, A.G.1    Reed, N.S.2    Ralston, S.H.3
  • 29
    • 0032956195 scopus 로고    scopus 로고
    • Double-blind, randomised, placebo-controlled, dose-finding study of oral ibandronate in patients with metastatic bone disease
    • Coleman RE, Purohit OP, Black C, et al. Double-blind, randomised, placebo-controlled, dose-finding study of oral ibandronate in patients with metastatic bone disease. Ann Oncol. 1999;10(3):311-316.
    • (1999) Ann Oncol , vol.10 , Issue.3 , pp. 311-316
    • Coleman, R.E.1    Purohit, O.P.2    Black, C.3
  • 30
    • 1942501727 scopus 로고    scopus 로고
    • Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: Results from two randomised, placebo-controlled phase III studies
    • Body JJ, Diel IJ, Lichinitzer M, et al. Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies. Br J Cancer. 2004;90(6):1133-1137.
    • (2004) Br J Cancer , vol.90 , Issue.6 , pp. 1133-1137
    • Body, J.J.1    Diel, I.J.2    Lichinitzer, M.3
  • 31
    • 77954577009 scopus 로고    scopus 로고
    • Bisphosphonate-induced osteonecrosis of the jaw: A review of 2,400 patient cases
    • Filleul O, Crompot E, Saussez S. Bisphosphonate-induced osteonecrosis of the jaw: a review of 2,400 patient cases. J Cancer Res Clin Oncol. 2010;136(8):1117-1124.
    • (2010) J Cancer Res Clin Oncol , vol.136 , Issue.8 , pp. 1117-1124
    • Filleul, O.1    Crompot, E.2    Saussez, S.3
  • 32
    • 75449117669 scopus 로고    scopus 로고
    • Bisphosphonates and time to osteonecrosis development
    • Palaska PK, Cartsos V, Zavras AI. Bisphosphonates and time to osteonecrosis development. Oncologist. 2009;14(11):1154-1166.
    • (2009) Oncologist , vol.14 , Issue.11 , pp. 1154-1166
    • Palaska, P.K.1    Cartsos, V.2    Zavras, A.I.3
  • 33
    • 69949108393 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw in breast cancer patients: Recommendations for prevention and treatment
    • Fehm T, Felsenberg D, Krimmel M, et al. Bisphosphonate-associated osteonecrosis of the jaw in breast cancer patients: recommendations for prevention and treatment. Breast. 2009;18(4):213-217.
    • (2009) Breast , vol.18 , Issue.4 , pp. 213-217
    • Fehm, T.1    Felsenberg, D.2    Krimmel, M.3
  • 34
    • 35348897212 scopus 로고    scopus 로고
    • Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases
    • Lipton A, Steger GG, Figueroa J, et al. Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases. J Clin Oncol. 2007;25(28):4431-4437.
    • (2007) J Clin Oncol , vol.25 , Issue.28 , pp. 4431-4437
    • Lipton, A.1    Steger, G.G.2    Figueroa, J.3
  • 35
    • 79551568488 scopus 로고    scopus 로고
    • Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study
    • Stopeck AT, Lipton A, Body JJ, et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol. 2010;28(35):5132-5139.
    • (2010) J Clin Oncol , vol.28 , Issue.35 , pp. 5132-5139
    • Stopeck, A.T.1    Lipton, A.2    Body, J.J.3
  • 36
    • 0034659772 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein as a potential target of therapy for cancer-associated morbidity
    • Ogata E. Parathyroid hormone-related protein as a potential target of therapy for cancer-associated morbidity. Cancer. 2000;88(12 suppl): 2909-2911.
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 2909-2911
    • Ogata, E.1
  • 37
    • 0036853893 scopus 로고    scopus 로고
    • Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo
    • Gallwitz WE, Guise TA, Mundy GR. Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo. J Clin Invest. 2002;110(10):1559-1572.
    • (2002) J Clin Invest , vol.110 , Issue.10 , pp. 1559-1572
    • Gallwitz, W.E.1    Guise, T.A.2    Mundy, G.R.3
  • 38
    • 0032918414 scopus 로고    scopus 로고
    • TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
    • Yin JJ, Selander K, Chirgwin JM, et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest. 1999;103(2):197-206.
    • (1999) J Clin Invest , vol.103 , Issue.2 , pp. 197-206
    • Yin, J.J.1    Selander, K.2    Chirgwin, J.M.3
  • 39
    • 79952278967 scopus 로고    scopus 로고
    • The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: Results of a 4-week, double-blind, randomized, controlled trial
    • Jensen AB, Wynne C, Ramirez G, et al. The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. Clin Breast Cancer. 2010;10(6):452-458.
    • (2010) Clin Breast Cancer , vol.10 , Issue.6 , pp. 452-458
    • Jensen, A.B.1    Wynne, C.2    Ramirez, G.3
  • 40
    • 34250865694 scopus 로고    scopus 로고
    • Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases
    • Zhao Y, Bachelier R, Treilleux I, et al. Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases. Cancer Res. 2007;67(12):5821-5830.
    • (2007) Cancer Res , vol.67 , Issue.12 , pp. 5821-5830
    • Zhao, Y.1    Bachelier, R.2    Treilleux, I.3
  • 41
    • 0141479984 scopus 로고    scopus 로고
    • A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases
    • Yin JJ, Mohammad KS, Käkönen SM, et al. A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proc Natl Acad Sci U S A. 2003;100(19):10954-10959.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.19 , pp. 10954-10959
    • Yin, J.J.1    Mohammad, K.S.2    Käkönen, S.M.3
  • 42
    • 0037441843 scopus 로고    scopus 로고
    • Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: A randomized, phase II, placebocontrolled trial
    • Carducci MA, Padley RJ, Breul J, et al. Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebocontrolled trial. J Clin Oncol. 2003;21(4):679-689.
    • (2003) J Clin Oncol , vol.21 , Issue.4 , pp. 679-689
    • Carducci, M.A.1    Padley, R.J.2    Breul, J.3
  • 43
    • 74949100969 scopus 로고    scopus 로고
    • Pathogenesis of myeloma bone disease
    • Roodman GD. Pathogenesis of myeloma bone disease. J Cell Biochem. 2010;109(2):283-291.
    • (2010) J Cell Biochem , vol.109 , Issue.2 , pp. 283-291
    • Roodman, G.D.1
  • 44
    • 54049156803 scopus 로고    scopus 로고
    • Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
    • Breitkreutz I, Raab MS, Vallet S, et al. Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma. Leukemia. 2008;22(10):1925-1932.
    • (2008) Leukemia , vol.22 , Issue.10 , pp. 1925-1932
    • Breitkreutz, I.1    Raab, M.S.2    Vallet, S.3
  • 45
    • 0032491037 scopus 로고    scopus 로고
    • Reduction in new metastases in breast cancer with adjuvant clodronate treatment
    • Diel IJ, Solomayer EF, Costa SD, et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med. 1998;339(6):357-363.
    • (1998) N Engl J Med , vol.339 , Issue.6 , pp. 357-363
    • Diel, I.J.1    Solomayer, E.F.2    Costa, S.D.3
  • 46
    • 33744828376 scopus 로고    scopus 로고
    • Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
    • Powles T, Paterson A, McCloskey E, et al. Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Res. 2006;8(2):R13.
    • (2006) Breast Cancer Res , vol.8 , Issue.2
    • Powles, T.1    Paterson, A.2    McCloskey, E.3
  • 47
    • 0035148170 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in nodepositive breast cancer patients: 5-year results of a randomized controlled trial
    • Saarto T, Blomqvist C, Virkkunen P, et al. Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in nodepositive breast cancer patients: 5-year results of a randomized controlled trial. J Clin Oncol. 2001;19(1):10-17.
    • (2001) J Clin Oncol , vol.19 , Issue.1 , pp. 10-17
    • Saarto, T.1    Blomqvist, C.2    Virkkunen, P.3
  • 48
    • 9444254706 scopus 로고    scopus 로고
    • Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in nodepositive breast cancer patients
    • Saarto T, Vehmanen L, Virkkunen P, et al. Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in nodepositive breast cancer patients. Acta Oncol. 2004;43(7):650-656.
    • (2004) Acta Oncol , vol.43 , Issue.7 , pp. 650-656
    • Saarto, T.1    Vehmanen, L.2    Virkkunen, P.3
  • 49
    • 72849140888 scopus 로고    scopus 로고
    • Bisphosphonates in the prevention of disease recurrence: Current results and ongoing trials
    • Gnant M. Bisphosphonates in the prevention of disease recurrence: current results and ongoing trials. Curr Cancer Drug Targets. 2009;9(7):824-833.
    • (2009) Curr Cancer Drug Targets , vol.9 , Issue.7 , pp. 824-833
    • Gnant, M.1
  • 50
    • 79958182699 scopus 로고    scopus 로고
    • Safety of zoledronic acid and incidence of osteonecrosis of the jaw (ONJ) during adjuvant therapy in a randomised phase III trial (AZURE: BIG 01-04) for women with stage II/ III breast cancer
    • Coleman R, Woodward E, Brown J, et al. Safety of zoledronic acid and incidence of osteonecrosis of the jaw (ONJ) during adjuvant therapy in a randomised phase III trial (AZURE: BIG 01-04) for women with stage II/ III breast cancer. Breast Cancer Res Treat. 2011;127(2):429-438.
    • (2011) Breast Cancer Res Treat , vol.127 , Issue.2 , pp. 429-438
    • Coleman, R.1    Woodward, E.2    Brown, J.3
  • 51
    • 36549039108 scopus 로고    scopus 로고
    • Emerging strategies in bone health management for the adjuvant patient
    • Coleman RE. Emerging strategies in bone health management for the adjuvant patient. Semin Oncol. 2007;34(6 suppl 4):S11-S16.
    • (2007) Semin Oncol , vol.34 , Issue.6 SUPPL. 4
    • Coleman, R.E.1
  • 52
    • 0023200599 scopus 로고
    • Reduced morbidity from skeletal metastases in breast cancer patients during long-term bisphosphonate (APD) treatment
    • van Holten-Verzantvoort AT, Bijvoet OL, Cleton FJ, et al. Reduced morbidity from skeletal metastases in breast cancer patients during long-term bisphosphonate (APD) treatment. Lancet. 1987;2(8566):983-985.
    • (1987) Lancet , vol.2 , Issue.8566 , pp. 983-985
    • van Holten-Verzantvoort, A.T.1    Bijvoet, O.L.2    Cleton, F.J.3
  • 53
    • 0027512788 scopus 로고
    • Palliative pamidronate treatment in patients with bone metastases from breast cancer
    • van Holten-Verzantvoort AT, Kroon HM, Bijvoet OL, et al. Palliative pamidronate treatment in patients with bone metastases from breast cancer. J Clin Oncol. 1993;11(3):491-498.
    • (1993) J Clin Oncol , vol.11 , Issue.3 , pp. 491-498
    • van Holten-Verzantvoort, A.T.1    Kroon, H.M.2    Bijvoet, O.L.3
  • 54
    • 0025832917 scopus 로고
    • The effect of supportive pamidronate treatment on aspects of quality of life of patients with advanced breast cancer
    • van Holten-Verzantvoort AT, Zwinderman AH, Aaronson NK, et al. The effect of supportive pamidronate treatment on aspects of quality of life of patients with advanced breast cancer. Eur J Cancer. 1991;27(5):544-549.
    • (1991) Eur J Cancer , vol.27 , Issue.5 , pp. 544-549
    • van Holten-Verzantvoort, A.T.1    Zwinderman, A.H.2    Aaronson, N.K.3
  • 55
    • 0029968633 scopus 로고    scopus 로고
    • Does supportive pamidronate treatment prevent or delay the first manifestation of bone metastases in breast cancer patients?
    • van Holten-Verzantvoort AT, Hermans J, Beex LV, et al. Does supportive pamidronate treatment prevent or delay the first manifestation of bone metastases in breast cancer patients? Eur J Cancer. 1996;32A(3):450-454.
    • (1996) Eur J Cancer , vol.32 A , Issue.3 , pp. 450-454
    • van Holten-Verzantvoort, A.T.1    Hermans, J.2    Beex, L.V.3
  • 56
    • 0029782630 scopus 로고    scopus 로고
    • Delay in progression of bone metastases in breast cancer patients treated with intravenous pamidronate: Results from a multinational randomized controlled trial
    • The Aredia Multinational Cooperative Group
    • Conte PF, Latreille J, Mauriac L, et al. Delay in progression of bone metastases in breast cancer patients treated with intravenous pamidronate: results from a multinational randomized controlled trial. The Aredia Multinational Cooperative Group. J Clin Oncol. 1996;14(9):2552-2559.
    • (1996) J Clin Oncol , vol.14 , Issue.9 , pp. 2552-2559
    • Conte, P.F.1    Latreille, J.2    Mauriac, L.3
  • 57
    • 0033050818 scopus 로고    scopus 로고
    • Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial
    • Protocol 18 Aredia Breast Cancer Study Group
    • Theriault RL, Lipton A, Hortobagyi GN, et al. Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. J Clin Oncol. 1999;17(3):846-854.
    • (1999) J Clin Oncol , vol.17 , Issue.3 , pp. 846-854
    • Theriault, R.L.1    Lipton, A.2    Hortobagyi, G.N.3
  • 58
    • 0034162528 scopus 로고    scopus 로고
    • Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials
    • Lipton A, Theriault RL, Hortobagyi GN, et al. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials. Cancer. 2000;88(5):1082-1090.
    • (2000) Cancer , vol.88 , Issue.5 , pp. 1082-1090
    • Lipton, A.1    Theriault, R.L.2    Hortobagyi, G.N.3
  • 59
    • 0035312469 scopus 로고    scopus 로고
    • Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases
    • Berenson JR, Rosen LS, Howell A, et al. Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases. Cancer. 2001;91(7):1191-1200.
    • (2001) Cancer , vol.91 , Issue.7 , pp. 1191-1200
    • Berenson, J.R.1    Rosen, L.S.2    Howell, A.3
  • 60
    • 10744233992 scopus 로고    scopus 로고
    • Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion
    • Rosen LS, Gordon DH, Dugan W Jr, et al. Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion. Cancer. 2004;100(1):36-43.
    • (2004) Cancer , vol.100 , Issue.1 , pp. 36-43
    • Rosen, L.S.1    Gordon, D.H.2    Dugan Jr., W.3
  • 61
    • 35348976664 scopus 로고    scopus 로고
    • Ibandronate is effective in preventing skeletal events in patients with bone metastases from colorectal cancer
    • Heras P, Karagiannis S, Kritikos K, et al. Ibandronate is effective in preventing skeletal events in patients with bone metastases from colorectal cancer. Eur J Cancer Care (Engl). 2007;16(6):539-542.
    • (2007) Eur J Cancer Care (Engl) , vol.16 , Issue.6 , pp. 539-542
    • Heras, P.1    Karagiannis, S.2    Kritikos, K.3
  • 62
    • 70350502817 scopus 로고    scopus 로고
    • Efficacy of ibandronate for the treatment of skeletal events in patients with metastatic breast cancer
    • Heras P, Kritikos K, Hatzopoulos A, et al. Efficacy of ibandronate for the treatment of skeletal events in patients with metastatic breast cancer. Eur J Cancer Care (Engl). 2009;18(6):653-656.
    • (2009) Eur J Cancer Care (Engl) , vol.18 , Issue.6 , pp. 653-656
    • Heras, P.1    Kritikos, K.2    Hatzopoulos, A.3
  • 63
    • 9044238068 scopus 로고    scopus 로고
    • Randomized phase II trial comparing different doses of the bisphosphonate ibandronate in the treatment of hypercalcemia of malignancy
    • Pecherstorfer M, Herrmann Z, Body JJ, et al. Randomized phase II trial comparing different doses of the bisphosphonate ibandronate in the treatment of hypercalcemia of malignancy. J Clin Oncol. 1996;14:268-276.
    • (1996) J Clin Oncol , vol.14 , pp. 268-276
    • Pecherstorfer, M.1    Herrmann, Z.2    Body, J.J.3
  • 64
    • 0041733424 scopus 로고    scopus 로고
    • Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: A randomized multicentric comparison to pamidronate
    • Pecherstorfer M, Steinhauer EU, Rizzoli R, et al. Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. Support Care Cancer. 2003;11(8):539-547.
    • (2003) Support Care Cancer , vol.11 , Issue.8 , pp. 539-547
    • Pecherstorfer, M.1    Steinhauer, E.U.2    Rizzoli, R.3
  • 65
    • 17144447171 scopus 로고    scopus 로고
    • Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
    • Body JJ, Diel IJ, Lichinitser MR, et al. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann Oncol. 2003;14(9):1399-1405.
    • (2003) Ann Oncol , vol.14 , Issue.9 , pp. 1399-1405
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 66
    • 0042331464 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial)
    • Dearnaley DP, Sydes MR, Mason MD, et al. A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial). J Natl Cancer Inst. 2003;95(17):1300-1311.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.17 , pp. 1300-1311
    • Dearnaley, D.P.1    Sydes, M.R.2    Mason, M.D.3
  • 67
    • 17444435152 scopus 로고    scopus 로고
    • Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases [Article in French]
    • Tubiana-Hulin M, Beuzeboc P, Mauriac L, et al. Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases [Article in French]. Bull Cancer. 2001;88(7):701-707.
    • (2001) Bull Cancer , vol.88 , Issue.7 , pp. 701-707
    • Tubiana-Hulin, M.1    Beuzeboc, P.2    Mauriac, L.3
  • 68
    • 13144294096 scopus 로고    scopus 로고
    • A double blind randomized study of oral clodronate in the treatment of bone metastases from tumors poorly responsive to chemotherapy
    • Piga A, Bracci R, Ferretti B, et al. A double blind randomized study of oral clodronate in the treatment of bone metastases from tumors poorly responsive to chemotherapy. J Exp Clin Cancer Res. 1998;17(2):213-217.
    • (1998) J Exp Clin Cancer Res , vol.17 , Issue.2 , pp. 213-217
    • Piga, A.1    Bracci, R.2    Ferretti, B.3
  • 69
    • 79952360832 scopus 로고    scopus 로고
    • Denosumab versus zoledronic acid for treatment of bone metastases in men with castrationresistant prostate cancer: A randomised, double-blind study
    • Fizazi K, Carducci M, Smith M, et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castrationresistant prostate cancer: a randomised, double-blind study. Lancet. 2011; 377(9768):813-822.
    • (2011) Lancet , vol.377 , Issue.9768 , pp. 813-822
    • Fizazi, K.1    Carducci, M.2    Smith, M.3
  • 70
    • 63749094012 scopus 로고    scopus 로고
    • Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
    • Fizazi K, Lipton A, Mariette X, et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol. 2009;27(10):1564-1571.
    • (2009) J Clin Oncol , vol.27 , Issue.10 , pp. 1564-1571
    • Fizazi, K.1    Lipton, A.2    Mariette, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.